(PDF) Red Blood Cell Transfusion in Patients With Autoantibodies: Is It
(PDF) Red blood cell transfusion in sickle cell disease
(PDF) Liberal versus restrictive red blood cell transfusion strategy in
(PDF) Understanding the Association between Red Blood Cell Transfusion
(PDF) Association between red blood cell transfusion and
(PDF) Restrictive versus liberal transfusion strategy for red blood
COMMENTS
Red blood cell transfusion policy: a critical literature review
Abstract. The issue of the most appropriate red blood cell transfusion policy has been addressed by a number of randomised controlled trials, conducted over the last decades, comparing the effects on patients' outcome of restrictive blood transfusion strategies (transfusing when the haemoglobin concentration is less than 7 g/dL to 8 g/dL) vs ...
Red blood cell transfusion policy: a critical literature review
Various systematic reviews and meta-analyses have tried to perform pooled analyses of the data from these randomised controlled trials and their results have been utilised by scientific societies to provide recommendations and guidelines on red blood cell transfusion thresholds. The issue of the most appropriate red blood cell transfusion policy has been addressed by a number of randomised ...
Red Blood Cell Transfusion—AABB Guidelines
Importance Red blood cell transfusion is a common medical intervention with benefits and harms.. Objective To provide recommendations for use of red blood cell transfusion in adults and children.. Evidence Review Standards for trustworthy guidelines were followed, including using Grading of Recommendations Assessment, Development and Evaluation methods, managing conflicts of interest, and ...
Patient Blood Management: a revolutionary approach to transfusion
Patient Blood Management in surgical settings. In association with the improvement of surgical techniques, a number of transfusion and non-transfusion measures have been implemented over the last decades to minimise perioperative blood loss 4.Among PBM-related transfusion strategies, the issue of the most appropriate red blood cell (RBC) transfusion policy is particularly critical.
Blood Transfusion Reactions—A Comprehensive Review of the Literature
No universal definition for massive transfusion (MT) is found in the current literature, but the persistent transfusion requirement of >4 packed red cells (approximately 1000 mL) within 1 h or the transfusion of 10 units of packed red blood cells within a 24 h period is a commonly accepted definition in clinical settings .
Evidence-based practice for red blood cell transfusions
This focus, known as PBM, has led to a critical review of transfusion practices and determination of best practices for evidence-based patient care. PBM is an evidence-based, multidisciplinary approach to optimizing the care of patients who might need a transfusion. 8 Blood management goes beyond transfusions to include alternative treatment ...
Quality of Evidence-Based Guidelines for Transfusion of Red Blood Cells
Quality of Evidence-Based Guidelines for Transfusion of Red Blood Cells and Plasma: A Systematic Review Transfus Med Rev. 2018 Jun 1:S0887-7963 ... described a systematic search strategy, included critical appraisal of the literature and a description of how recommendations were developed. Four to six physicians used AGREE II to appraise each ...
Transfusion thresholds for guiding red blood cell transfusion
The following differences were applied in this 2021 version of the review. We changed the title of the review from "Transfusion thresholds and other strategies for guiding allogeneic red blood cell transfusion" to "Transfusion thresholds for guiding red blood cell transfusion". The authors of the review have changed ‐ two new authors have ...
Red blood cell transfusion to treat or prevent ...
Okusanya 2016Prophylactic versus selective blood transfusion for sickle cell disease in pregnancy . To assess the benefits and harms of a policy of prophylactic versus. selective blood transfusion in pregnant women with SCD. 30 May 2016 /30 May 2016. Prophylactic transfusion: to optimise Hb concentration to a specified level
Efficacy of red blood cell transfusion in the critically ill: a
Abstract. Background: Red blood cell (RBC) transfusions are common in intensive care unit, trauma, and surgical patients. However, the hematocrit that should be maintained in any particular patient because the risks of further transfusion of RBC outweigh the benefits remains unclear. Objective: A systematic review of the literature to determine ...
Implementation of a Comprehensive Patient Blood Management Program for
In 2019, more than 10 million red blood cell (RBC) units, 2 million plasma units, and 2 million platelet units were transfused in the United States, making blood transfusions one of the most common procedures performed during hospitalization. 1 Although the number of transfusions had risen over time to support more advanced treatments and procedures, the rate of growth in the early to mid ...
Pre‐hospital transfusion of red blood cells. Part 1: A scoping review
1 INTRODUCTION. Trauma is a major cause of death and disability. 1, 2 In injured patients, death within 24 hours is primarily attributable to haemorrhage, 3-5 and many of these deaths are potentially preventable. 6-8 To optimise bleeding patients' odds of survival, pre-hospital treatment focuses on early haemorrhage control to avoid hypovolaemic shock and the lethal triad of acidosis ...
Red blood cell transfusion policy: a critical literature review
Abstract. The issue of the most appropriate red blood cell transfusion policy has been addressed by a number of randomised controlled trials, conducted over the last decades, comparing the effects on patients' outcome of restrictive blood transfusion strategies (transfusing when the haemoglobin concentration is less than 7 g/dL to 8 g/dL) vs ...
PDF A Compendium of Transfusion Practice Guidelines
superiority, of restrictive red cell transfusion practices. This is supported by the results of the latest National Blood Collection ... This compendium is a review of the current blood usage guidelines published in English in peer-reviewed journals. Whenever possible, RCTs are included, but where lacking, the discussion is informed by expert ...
Definitions of massive transfusion in adults with critical bleeding: a
Major bleeding requiring blood transfusion can occur in almost any clinical setting and is a medical emergency [].The impact of blood component transfusion and other haemostatic interventions on improving outcomes of bleeding patients has been a topic of increasing research interest, as demonstrated by multiple recent randomised controlled trials (RCT) [2, 3], giving momentum to trials ...
Quality of clinical practice guidelines about red blood cell transfusion
1. INTRODUCTION. Blood transfusion is the infusion of both soluble and cell‐associated forms like RBCs, white blood cells, and platelets into a recipient.1 A blood transfusion is an acute intervention, implemented to solve life and health‐threatening conditions on a short‐term basis.2, 3 However, RBCs and other blood components therapies have been associated with several adverse clinical ...
Red blood cell transfusion policy: A critical literature review
Abstract. The issue of the most appropriate red blood cell transfusion policy has been addressed by a number of randomised controlled trials, conducted over the last decades, comparing the effects ...
A Contemporary Review of Blood Transfusion in Critically Ill Patients
A contemporary review of transfusion practices in ICU patients has constantly evolved and is presented, guided by clinical trials and expert guidelines. Blood transfusion is a common therapeutic intervention in hospitalized patients. There are numerous indications for transfusion, including anemia and coagulopathy with deficiency of single or multiple coagulation components such as platelets ...
The Risks Associated with Red Blood Cell Transfusion ...
This systematic literature review informs the clinician caring for the critically ill patient of the risks associated with red blood cell (RBC) transfusion. Data were extracted from publications between 2008 and 2016 and were reviewed to determine their usefulness in providing evidence associated with the risk of receiving an RBC transfusion.
Clinical Practice Guideline: Red Blood Cell Transfusion in Adult ...
2. To review the evidence regarding risks of RBC transfu-sion in trauma and critical care. 3. To review indications for RBC transfusion in critically ill and injured patients. 4. To review possible alternatives to RBC transfusions. 5. To review practices that have been associated with de-creased need for RBC transfusion. PROCESS
Red cell Alloimmunization and its Correlation with Clinical ...
Background Thalassemia is the most frequent congenital cause of anemia globally, categorized by anomalous hemoglobin production. Lifelong PRBC transfusion with iron chelation therapy is the only therapeutic option available for the majority. Long-term recurrent blood transfusion has its hindrances like RBC alloimmunization. As there is inadequate data on alloimmunization in the pediatric ...
Ways To Enhance Blood Transfusion Safety: A Systematic Review
This systematic review aimed to present factors reducing patient safety during blood transfusion and ways of improving patient safety. For this purpose, electronic databases, including PubMed/MEDLINE, EMBASE, Web of Science, Cochrane CENTRAL, Scopus, and Google Scholar, were systematically searched from 1990 to the end of 2020 using the ...
Effects of red blood cell transfusion on patients undergoing cardiac
Background Packed red blood cell (pRBC) transfusion is a relatively safe and mainstay treatment commonly used in cardiac surgical patients. However, there is limited evidence on clinical effects of transfusing blood nearing end-of shelf life that has undergone biochemical changes during storage. Objective To investigate evidence of associations between morbidity/mortality and transfusion of ...
Markers of Futile Resuscitation in Traumatic Hemorrhage: A Review of
The reduction in the blood supply following the 2019 coronavirus pandemic has been exacerbated by the increased use of balanced resuscitation with blood components including whole blood in urban trauma centers. This reduction of the blood supply has diminished the ability of blood banks to maintain a constant supply to meet the demands associated with periodic surges of urban trauma resuscitation.
Clinical practice guideline: red blood cell transfusion in adult trauma
Objective: To develop a clinical practice guideline for red blood cell transfusion in adult trauma and critical care. Design: Meetings, teleconferences and electronic-based communication to achieve grading of the published evidence, discussion and consensus among the entire committee members. Methods: This practice management guideline was developed by a joint taskforce of EAST (Eastern ...
Recommendations on Red Blood Cell Transfusion Support in Children with
In children with SCD and pulmonary hypertension who are critically ill or at risk for critical illness, there is insufficient evidence to recommend the optimal Hb concentration threshold or percent HbS for RBC transfusion or the method of red cell transfusion. Consensus panel expertise. Voting data (n=35): 97% agreement, median 9, IQR 8-9.
International Prehospital Medicine Institute Literature Review ...
This literature review keeps you up to date with current EMS publications and studies. ... the blood transfusion process but also blood transfusion theory, the physiology of hemorrhagic shock, and ...
Red blood cell transfusion in critically ill children: a narrative review
Abstract. Objective: To review the pathophysiology of anemia, as well as transfusion-related complications and indications for red blood cell (RBC) transfusion, in critically ill children. Although allogeneic blood has become increasingly safer from infectious agents, mounting evidence indicates that RBC transfusions are associated with ...
IMAGES
COMMENTS
Abstract. The issue of the most appropriate red blood cell transfusion policy has been addressed by a number of randomised controlled trials, conducted over the last decades, comparing the effects on patients' outcome of restrictive blood transfusion strategies (transfusing when the haemoglobin concentration is less than 7 g/dL to 8 g/dL) vs ...
Various systematic reviews and meta-analyses have tried to perform pooled analyses of the data from these randomised controlled trials and their results have been utilised by scientific societies to provide recommendations and guidelines on red blood cell transfusion thresholds. The issue of the most appropriate red blood cell transfusion policy has been addressed by a number of randomised ...
Importance Red blood cell transfusion is a common medical intervention with benefits and harms.. Objective To provide recommendations for use of red blood cell transfusion in adults and children.. Evidence Review Standards for trustworthy guidelines were followed, including using Grading of Recommendations Assessment, Development and Evaluation methods, managing conflicts of interest, and ...
Patient Blood Management in surgical settings. In association with the improvement of surgical techniques, a number of transfusion and non-transfusion measures have been implemented over the last decades to minimise perioperative blood loss 4.Among PBM-related transfusion strategies, the issue of the most appropriate red blood cell (RBC) transfusion policy is particularly critical.
No universal definition for massive transfusion (MT) is found in the current literature, but the persistent transfusion requirement of >4 packed red cells (approximately 1000 mL) within 1 h or the transfusion of 10 units of packed red blood cells within a 24 h period is a commonly accepted definition in clinical settings .
This focus, known as PBM, has led to a critical review of transfusion practices and determination of best practices for evidence-based patient care. PBM is an evidence-based, multidisciplinary approach to optimizing the care of patients who might need a transfusion. 8 Blood management goes beyond transfusions to include alternative treatment ...
Quality of Evidence-Based Guidelines for Transfusion of Red Blood Cells and Plasma: A Systematic Review Transfus Med Rev. 2018 Jun 1:S0887-7963 ... described a systematic search strategy, included critical appraisal of the literature and a description of how recommendations were developed. Four to six physicians used AGREE II to appraise each ...
The following differences were applied in this 2021 version of the review. We changed the title of the review from "Transfusion thresholds and other strategies for guiding allogeneic red blood cell transfusion" to "Transfusion thresholds for guiding red blood cell transfusion". The authors of the review have changed ‐ two new authors have ...
Okusanya 2016Prophylactic versus selective blood transfusion for sickle cell disease in pregnancy . To assess the benefits and harms of a policy of prophylactic versus. selective blood transfusion in pregnant women with SCD. 30 May 2016 /30 May 2016. Prophylactic transfusion: to optimise Hb concentration to a specified level
Abstract. Background: Red blood cell (RBC) transfusions are common in intensive care unit, trauma, and surgical patients. However, the hematocrit that should be maintained in any particular patient because the risks of further transfusion of RBC outweigh the benefits remains unclear. Objective: A systematic review of the literature to determine ...
In 2019, more than 10 million red blood cell (RBC) units, 2 million plasma units, and 2 million platelet units were transfused in the United States, making blood transfusions one of the most common procedures performed during hospitalization. 1 Although the number of transfusions had risen over time to support more advanced treatments and procedures, the rate of growth in the early to mid ...
1 INTRODUCTION. Trauma is a major cause of death and disability. 1, 2 In injured patients, death within 24 hours is primarily attributable to haemorrhage, 3-5 and many of these deaths are potentially preventable. 6-8 To optimise bleeding patients' odds of survival, pre-hospital treatment focuses on early haemorrhage control to avoid hypovolaemic shock and the lethal triad of acidosis ...
Abstract. The issue of the most appropriate red blood cell transfusion policy has been addressed by a number of randomised controlled trials, conducted over the last decades, comparing the effects on patients' outcome of restrictive blood transfusion strategies (transfusing when the haemoglobin concentration is less than 7 g/dL to 8 g/dL) vs ...
superiority, of restrictive red cell transfusion practices. This is supported by the results of the latest National Blood Collection ... This compendium is a review of the current blood usage guidelines published in English in peer-reviewed journals. Whenever possible, RCTs are included, but where lacking, the discussion is informed by expert ...
Major bleeding requiring blood transfusion can occur in almost any clinical setting and is a medical emergency [].The impact of blood component transfusion and other haemostatic interventions on improving outcomes of bleeding patients has been a topic of increasing research interest, as demonstrated by multiple recent randomised controlled trials (RCT) [2, 3], giving momentum to trials ...
1. INTRODUCTION. Blood transfusion is the infusion of both soluble and cell‐associated forms like RBCs, white blood cells, and platelets into a recipient.1 A blood transfusion is an acute intervention, implemented to solve life and health‐threatening conditions on a short‐term basis.2, 3 However, RBCs and other blood components therapies have been associated with several adverse clinical ...
Abstract. The issue of the most appropriate red blood cell transfusion policy has been addressed by a number of randomised controlled trials, conducted over the last decades, comparing the effects ...
A contemporary review of transfusion practices in ICU patients has constantly evolved and is presented, guided by clinical trials and expert guidelines. Blood transfusion is a common therapeutic intervention in hospitalized patients. There are numerous indications for transfusion, including anemia and coagulopathy with deficiency of single or multiple coagulation components such as platelets ...
This systematic literature review informs the clinician caring for the critically ill patient of the risks associated with red blood cell (RBC) transfusion. Data were extracted from publications between 2008 and 2016 and were reviewed to determine their usefulness in providing evidence associated with the risk of receiving an RBC transfusion.
2. To review the evidence regarding risks of RBC transfu-sion in trauma and critical care. 3. To review indications for RBC transfusion in critically ill and injured patients. 4. To review possible alternatives to RBC transfusions. 5. To review practices that have been associated with de-creased need for RBC transfusion. PROCESS
Background Thalassemia is the most frequent congenital cause of anemia globally, categorized by anomalous hemoglobin production. Lifelong PRBC transfusion with iron chelation therapy is the only therapeutic option available for the majority. Long-term recurrent blood transfusion has its hindrances like RBC alloimmunization. As there is inadequate data on alloimmunization in the pediatric ...
This systematic review aimed to present factors reducing patient safety during blood transfusion and ways of improving patient safety. For this purpose, electronic databases, including PubMed/MEDLINE, EMBASE, Web of Science, Cochrane CENTRAL, Scopus, and Google Scholar, were systematically searched from 1990 to the end of 2020 using the ...
Background Packed red blood cell (pRBC) transfusion is a relatively safe and mainstay treatment commonly used in cardiac surgical patients. However, there is limited evidence on clinical effects of transfusing blood nearing end-of shelf life that has undergone biochemical changes during storage. Objective To investigate evidence of associations between morbidity/mortality and transfusion of ...
The reduction in the blood supply following the 2019 coronavirus pandemic has been exacerbated by the increased use of balanced resuscitation with blood components including whole blood in urban trauma centers. This reduction of the blood supply has diminished the ability of blood banks to maintain a constant supply to meet the demands associated with periodic surges of urban trauma resuscitation.
Objective: To develop a clinical practice guideline for red blood cell transfusion in adult trauma and critical care. Design: Meetings, teleconferences and electronic-based communication to achieve grading of the published evidence, discussion and consensus among the entire committee members. Methods: This practice management guideline was developed by a joint taskforce of EAST (Eastern ...
In children with SCD and pulmonary hypertension who are critically ill or at risk for critical illness, there is insufficient evidence to recommend the optimal Hb concentration threshold or percent HbS for RBC transfusion or the method of red cell transfusion. Consensus panel expertise. Voting data (n=35): 97% agreement, median 9, IQR 8-9.
This literature review keeps you up to date with current EMS publications and studies. ... the blood transfusion process but also blood transfusion theory, the physiology of hemorrhagic shock, and ...
Abstract. Objective: To review the pathophysiology of anemia, as well as transfusion-related complications and indications for red blood cell (RBC) transfusion, in critically ill children. Although allogeneic blood has become increasingly safer from infectious agents, mounting evidence indicates that RBC transfusions are associated with ...