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Molecular Biosciences Theses and Dissertations

Theses/dissertations from 2024 2024.

Androgen Drives Melanoma Invasiveness and Metastatic Spread by Inducing Tumorigenic Fucosylation , Qian Liu

Theses/Dissertations from 2023 2023

Exploring strain variation and bacteriophage predation in the gut microbiome of Ciona robusta , Celine Grace F. Atkinson

Distinct Nrf2 Signaling Thresholds Mediate Lung Tumor Initiation and Progression , Janine M. DeBlasi

Thermodynamic frustration of TAD2 and PRR contribute to autoinhibition of p53 , Emily Gregory

Utilization of Detonation Nanodiamonds: Nanocarrier for Gene Therapy in Non-Small Cell Lung Cancer , Allan E. Gutierrez

Utilizing neoantigen-specific CD4* T cells and immune checkpoint modulation to advance adoptive cell therapy with tumor-infiltrating lymphocytes for metastatic melanoma patients , Maclean Scott Hall

Role of HLA-DRB1 Fucosylation in Anti-Melanoma Immunity , Daniel K. Lester

Targeting BET Proteins Downregulates miR-33a To Promote Synergy with PIM Inhibitors in CMML , Christopher T. Letson

The Role of the DNA Helicase Rrm3 under Replication Stress , Julius Muellner

Regulated Intramembrane Proteolysis by M82 Peptidases: The Role of PrsS in the Staphylococcus aureus Stress Response , Baylie M. Schott

Histone Deacetylase 8 is a Novel Therapeutic Target for Mantle Cell Lymphoma and Preserves Natural Killer Cell Cytotoxic Function , January M. Watters

Theses/Dissertations from 2022 2022

Ceramide-1-Phosphate: A Novel Regulator of Golgi Fragmentation, Golgi-ER Vesicle Trafficking, and Anaplasma phagocytophilum Pathogenesis , Anika Nayar Ali

Regulation of the Heat Shock Response via Lysine Acetyltransferase CBP-1 and in Neurodegenerative Disease in Caenorhabditis elegans , Lindsey N. Barrett

Establishment of a Melanoma ESC-GEMM Platform and Its Use to Study PTEN Tumor Suppressor Functions , Ilah Bok

Adrenergic Modulation of Precursor Cells of Ovarian Cancer , Sweta Dash

Determining the Role of Dendritic Cells During Response to Treatment with Paclitaxel/Anti-TIM-3 , Alycia Gardner

To be or not to be: A Tale of Staphylococcal GpsB , Lauren R. Hammond

Origin and Epigenetic Regulation of Cutaneous T Cell Lymphoma , Carly M. Harro

Cell-free DNA Methylation Signatures in Cancer Detection and Classification , Jinyong Huang

The Role Of Eicosanoid Metabolism in Mammalian Wound Healing and Inflammation , Kenneth D. Maus

A Holistic Investigation of Acidosis in Breast Cancer , Bryce Ordway

Characterizing the Impact of Postharvest Temperature Stress on Polyphenol Profiles of Red and White-Fruited Strawberry Cultivars , Alyssa N. Smith

Identification of Secondary Structural Elements Contained Within the Intrinsically Disordered N-Terminal Tail of the Bloom’s Syndrome Helicase. , Vivek Somasundaram

Defining the role of Oxidized Mitochondrial DNA in Myelodysplastic Syndromes , Grace Anne Ward

Lord of the Z-rings: Uncovering the Role of MraZ and FtsL in Bacillus subtilis Cell Division , Maria Louise White

Theses/Dissertations from 2021 2021

Multifaceted Approach to Understanding Acinetobacter baumannii Biofilm Formation and Drug Resistance , Jessie L. Allen

Cellular And Molecular Alterations Associated with Ovarian and Renal Cancer Pathophysiology , Ravneet Kaur Chhabra

Ecology and diversity of boletes of the southeastern United States , Arian Farid

CircREV1 Expression in Triple-Negative Breast Cancer , Meagan P. Horton

Microbial Dark Matter: Culturing the Uncultured in Search of Novel Chemotaxonomy , Sarah J. Kennedy

The Multifaceted Role of CCAR-1 in the Alternative Splicing and Germline Regulation in Caenorhabditis elegans , Doreen Ikhuva Lugano

Unraveling the Role of Novel G5 Peptidase Family Proteins in Virulence and Cell Envelope Biogenesis of Staphylococcus aureus , Stephanie M. Marroquin

Cytoplasmic Polyadenylation Element Binding Protein 2 Alternative Splicing Regulates HIF1α During Chronic Hypoxia , Emily M. Mayo

Transcriptomic and Functional Investigation of Bacterial Biofilm Formation , Brooke R. Nemec

A Functional Characterization of the Omega (ω) subunit of RNA Polymerase in Staphylococcus aureus , Shrushti B. Patil

The Role Of Cpeb2 Alternative Splicing In TNBC Metastasis , Shaun C. Stevens

Screening Next-generation Fluorine-19 Probe and Preparation of Yeast-derived G Proteins for GPCR Conformation and Dynamics Study , Wenjie Zhao

Theses/Dissertations from 2020 2020

Understanding the Role of Cereblon in Hematopoiesis Through Structural and Functional Analyses , Afua Adutwumwa Akuffo

To Mid-cell and Beyond: Characterizing the Roles of GpsB and YpsA in Cell Division Regulation in Gram-positive Bacteria , Robert S. Brzozowski

Spatiotemporal Changes of Microbial Community Assemblages and Functions in the Subsurface , Madison C. Davis

New Mechanisms That Regulate DNA Double-Strand Break-Induced Gene Silencing and Genome Integrity , Dante Francis DeAscanis

Regulation of the Heat Shock Response and HSF-1 Nuclear Stress Bodies in C. elegans , Andrew Deonarine

New Mechanisms that Control FACT Histone Chaperone and Transcription-mediated Genome Stability , Angelo Vincenzo de Vivo Diaz

Targeting the ESKAPE Pathogens by Botanical and Microbial Approaches , Emily Dilandro

Succession in native groundwater microbial communities in response to effluent wastewater , Chelsea M. Dinon

Role of ceramide-1 phosphate in regulation of sphingolipid and eicosanoid metabolism in lung epithelial cells , Brittany A. Dudley

Allosteric Control of Proteins: New Methods and Mechanisms , Nalvi Duro

Microbial Community Structures in Three Bahamian Blue Holes , Meghan J. Gordon

A Novel Intramolecular Interaction in P53 , Fan He

The Impact of Myeloid-Mediated Co-Stimulation and Immunosuppression on the Anti-Tumor Efficacy of Adoptive T cell Therapy , Pasquale Patrick Innamarato

Investigating Mechanisms of Immune Suppression Secondary to an Inflammatory Microenvironment , Wendy Michelle Kandell

Posttranslational Modification and Protein Disorder Regulate Protein-Protein Interactions and DNA Binding Specificity of p53 , Robin Levy

Mechanistic and Translational Studies on Skeletal Malignancies , Jeremy McGuire

Novel Long Non-Coding RNA CDLINC Promotes NSCLC Progression , Christina J. Moss

Genome Maintenance Roles of Polycomb Transcriptional Repressors BMI1 and RNF2 , Anthony Richard Sanchez IV

The Ecology and Conservation of an Urban Karst Subterranean Estuary , Robert J. Scharping

Biological and Proteomic Characterization of Cornus officinalis on Human 1.1B4 Pancreatic β Cells: Exploring Use for T1D Interventional Application , Arielle E. Tawfik

Evaluation of Aging and Genetic Mutation Variants on Tauopathy , Amber M. Tetlow

Theses/Dissertations from 2019 2019

Investigating the Proteinaceous Regulome of the Acinetobacter baumannii , Leila G. Casella

Functional Characterization of the Ovarian Tumor Domain Deubiquitinating Enzyme 6B , Jasmin M. D'Andrea

Integrated Molecular Characterization of Lung Adenocarcinoma with Implications for Immunotherapy , Nicholas T. Gimbrone

The Role of Secreted Proteases in Regulating Disease Progression in Staphylococcus aureus , Brittney D. Gimza

Advanced Proteomic and Epigenetic Characterization of Ethanol-Induced Microglial Activation , Jennifer Guergues Guergues

Understanding immunometabolic and suppressive factors that impact cancer development , Rebecca Swearingen Hesterberg

Biochemical and Proteomic Approaches to Determine the Impact Level of Each Step of the Supply Chain on Tomato Fruit Quality , Robert T. Madden

Enhancing Immunotherapeutic Interventions for Treatment of Chronic Lymphocytic Leukemia , Kamira K. Maharaj

Characterization of the Autophagic-Iron Axis in the Pathophysiology of Endometriosis and Epithelial Ovarian Cancers , Stephanie Rockfield

Understanding the Influence of the Cancer Microenvironment on Metabolism and Metastasis , Shonagh Russell

Modeling of Interaction of Ions with Ether- and Ester-linked Phospholipids , Matthew W. Saunders

Novel Insights into the Multifaceted Roles of BLM in the Maintenance of Genome Stability , Vivek M. Shastri

Conserved glycine residues control transient helicity and disorder in the cold regulated protein, Cor15a , Oluwakemi Sowemimo

A Novel Cytokine Response Modulatory Function of MEK Inhibitors Mediates Therapeutic Efficacy , Mengyu Xie

Novel Strategies on Characterizing Biologically Specific Protein-protein Interaction Networks , Bi Zhao

Theses/Dissertations from 2018 2018

Characterization of the Transcriptional Elongation Factor ELL3 in B cells and Its Role in B-cell Lymphoma Proliferation and Survival , Lou-Ella M.m. Alexander

Identification of Regulatory miRNAs Associated with Ethanol-Induced Microglial Activation Using Integrated Proteomic and Transcriptomic Approaches , Brandi Jo Cook

Molecular Phylogenetics of Floridian Boletes , Arian Farid

MYC Distant Enhancers Underlie Ovarian Cancer Susceptibility at the 8q24.21 Locus , Anxhela Gjyshi Gustafson

Quantitative Proteomics to Support Translational Cancer Research , Melissa Hoffman

A Systems Chemical Biology Approach for Dissecting Differential Molecular Mechanisms of Action of Clinical Kinase Inhibitors in Lung Cancer , Natalia Junqueira Sumi

Investigating the Roles of Fucosylation and Calcium Signaling in Melanoma Invasion , Tyler S. Keeley

Synthesis, Oxidation, and Distribution of Polyphenols in Strawberry Fruit During Cold Storage , Katrina E. Kelly

Investigation of Alcohol-Induced Changes in Hepatic Histone Modifications Using Mass Spectrometry Based Proteomics , Crystina Leah Kriss

Off-Target Based Drug Repurposing Using Systems Pharmacology , Brent M. Kuenzi

Investigation of Anemarrhena asphodeloides and its Constituent Timosaponin-AIII as Novel, Naturally Derived Adjunctive Therapeutics for the Treatment of Advanced Pancreatic Cancer , Catherine B. MarElia

The Role of Phosphohistidine Phosphatase 1 in Ethanol-induced Liver Injury , Daniel Richard Martin

Theses/Dissertations from 2017 2017

Changing the Pathobiological Paradigm in Myelodysplastic Syndromes: The NLRP3 Inflammasome Drives the MDS Phenotype , Ashley Basiorka

Modeling of Dynamic Allostery in Proteins Enabled by Machine Learning , Mohsen Botlani-Esfahani

Uncovering Transcriptional Activators and Targets of HSF-1 in Caenorhabditis elegans , Jessica Brunquell

The Role of Sgs1 and Exo1 in the Maintenance of Genome Stability. , Lillian Campos-Doerfler

Mechanisms of IKBKE Activation in Cancer , Sridevi Challa

Discovering Antibacterial and Anti-Resistance Agents Targeting Multi-Drug Resistant ESKAPE Pathogens , Renee Fleeman

Functional Roles of Matrix Metalloproteinases in Bone Metastatic Prostate Cancer , Jeremy S. Frieling

Disorder Levels of c-Myb Transactivation Domain Regulate its Binding Affinity to the KIX Domain of CREB Binding Protein , Anusha Poosapati

Role of Heat Shock Transcription Factor 1 in Ovarian Cancer Epithelial-Mesenchymal Transition and Drug Sensitivity , Chase David Powell

Cell Division Regulation in Staphylococcus aureus , Catherine M. Spanoudis

A Novel Approach to the Discovery of Natural Products From Actinobacteria , Rahmy Tawfik

Non-classical regulators in Staphylococcus aureus , Andy Weiss

Theses/Dissertations from 2016 2016

In Vitro and In Vivo Antioxidant Capacity of Synthetic and Natural Polyphenolic Compounds Identified from Strawberry and Fruit Juices , Marvin Abountiolas

Quantitative Proteomic Investigation of Disease Models of Type 2 Diabetes , Mark Gabriel Athanason

CMG Helicase Assembly and Activation: Regulation by c-Myc through Chromatin Decondensation and Novel Therapeutic Avenues for Cancer Treatment , Victoria Bryant

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This collection of MIT Theses in DSpace contains selected theses and dissertations from all MIT departments. Please note that this is NOT a complete collection of MIT theses. To search all MIT theses, use MIT Libraries' catalog .

MIT's DSpace contains more than 58,000 theses completed at MIT dating as far back as the mid 1800's. Theses in this collection have been scanned by the MIT Libraries or submitted in electronic format by thesis authors. Since 2004 all new Masters and Ph.D. theses are scanned and added to this collection after degrees are awarded.

MIT Theses are openly available to all readers. Please share how this access affects or benefits you. Your story matters.

If you have questions about MIT theses in DSpace, [email protected] . See also Access & Availability Questions or About MIT Theses in DSpace .

If you are a recent MIT graduate, your thesis will be added to DSpace within 3-6 months after your graduation date. Please email [email protected] with any questions.

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Doctoral theses, graduate theses, undergraduate theses, recent submissions.

Transport Properties of Divertor Edge Plasmas Measured with Multi-Spectral Imaging 

Entanglement and Chaos in Quantum Field Theory and Gravity 

Illuminating the Cosmos: dark matter, primordial black holes, and cosmic dawn 

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Biotechnology Undergraduate Major

Undergraduate honors thesis in biotechnology, program description.

The Biotechnology major offers an Honors thesis option for highly motivated undergraduate students who are interested in professional careers in biological research. The series offers students a research experience that integrates hypothesis building, experimental design, experimental execution and written documentation. This option is available to students in any biologically oriented major on campus.

The overall structure of this series closely mimics that of successful graduate programs. Students participating in the thesis program enroll in three courses in addition to those required by their major. The first course, BIT188 Undergraduate research proposal writing, is taken spring quarter, typically the year before the student plans on graduating. In this writing intensive course, students work with the course instructor and individual faculty mentors to develop an experimental plan that addresses fundamental questions relating to the proposed thesis. In some cases the student has previously worked with the mentor on a 199, in other cases the instructor helps the student identify the mentor.

Following successful completion of BIT188, students enroll in BIT189L and undertake the proposed research. BIT189L is a variable unit course similar in format to 199s, the difference being that students in BIT189L have a thesis committee comprised of the faculty mentor, major advisor, and a third faculty member knowledgeable of the proposed research to direct and monitor the student’s progress.

The third component of the series, BIT194H, offers the students an opportunity to write up their research in an undergraduate thesis. This generally takes place the student’s last quarter before graduation. Satisfactory completion of the thesis is at the discretion of the student’s thesis committee.

Students that complete this program will have accomplished a complete research package from experimental design, execution, and write up. Completion of the program will be recognized by a passing grade in BIT194H: Honors Thesis in Biotechnology.  

COURSE DESCRIPTIONS

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Current research in biotechnology: Exploring the biotech forefront

2019, Current Research in Biotechnology

Biotechnology is an evolving research field that covers a broad range of topics. Here we aimed to evaluate the latest research literature, to identify prominent research themes, major contributors in terms of institutions, countries/re-gions, and journals. The Web of Science Core Collection online database was searched to retrieve biotechnology articles published since 2017. In total, 12,351 publications were identified and analyzed. Over 8500 institutions contributed to these biotechnology publications, with the top 5 most productive ones scattered over France, China, the United States of America, Spain, and Brazil. Over 140 countries/regions contributed to the biotechnology research literature, led by the United States of America, China, Germany, Brazil, and India. Journal of Bioscience and Bioengineer-ing was the most productive journal in terms of number of publications. Metabolic engineering was among the most prevalent biotechnology study themes, and Escherichia coli and Saccharomyces cerevisiae were frequently used in biotechnology investigations, including the biosynthesis of useful biomolecules, such as myo-inositol (vitamin B8), mono-terpenes, adipic acid, astaxanthin, and ethanol. Nanoparticles and nanotechnology were identified too as emerging biotechnology research themes of great significance. Biotechnology continues to evolve and will remain a major driver of societal innovation and development.

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Current Developments in Biotechnology and Bioengineering

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Scientists worldwide are continuing to discover unique properties of every day materials at the submicrometer scale. This size domain is better known as nanometer domain and technology concerned with this is known as nanotechnology that involves working with particles at nano level. One of the most important emerging fields of science in this centur y is Nanotechnology. It deals with designing, construction, investigation and utilization of systems at the nanoscale. The interface between nanotechnology and biotechnology is nanobiotechnology, which exploits nanotechnology and biotechnology to analyse a nd create nanobiosystems to meet a wide variety of challenges and develops a wide range of applications. Biotechnology gives us a way to understand biological system and to utilize our knowledge for industrial manufacturing. Nanotechnology has great potent ial and by the help of its application it can enhance the quality of life through in various fields like agriculture and the food system. Around the world, it has become the future of any nation. Important tools used in nanotechnology and application of nanobiotechnology in agriculture sector will be discussed in this review.

Revista Peruana de Biología

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Home > Life Sciences > Microbiology and Molecular Biology > Theses and Dissertations

Microbiology and Molecular Biology Theses and Dissertations

Theses/dissertations from 2024 2024.

Characterization of Cellular Metabolism Regulation by the Transcription Factor Centromere Binding Factor 1 (Cbf1) , Spencer Ellsworth

Connecting HIV-1 Viral Protein R Polymorphisms to Changes in Inflammatory Signals and Efficacy Testing of Essential Oils as Disinfectants Against SARS-CoV-2 , J. Brandon Lopez

The Effects of Combining β-lactam Antibiotics and Mefloquine in Multi-Drug ResistantPseudomonas aeruginosa , Kayla C. Maas

Laying Framework for a Novel In Vitro Eukaryotic System to Measure Rate of Transcription Elongation , John Lucas Ramirez

Theses/Dissertations from 2023 2023

Elucidating the Architecture of the TclIJN Complex that Converts Cysteine to Thiazoles in the Biosynthesis of Micrococcin , Diana G. Calvopina Chavez

Manipulating and Assaying Chromatin Architecture Around Enhancer Elements in vivo , John Lawrence Carter

Using de novo Transcriptomes to Decipher the Relationships in Cutthroat Trout Subspecies (Oncorhynchus clarkii) , Andrea Leena Kokkonen

Characterization of Phage-Host Interactions and its Impact on Tail Fiber Evolution , Jessica Marie Lewis

Halophilic Genes that Impact Plant Growth in Saline Soils , Mckay A. Meinzer

Characterizing Stress Granule Regulation by PAS Kinase, Ataxin-2 and Ptc6 and Investigating the Lifespan of Covid-19 Virus on Currency , Colleen R. Newey

Changes in RNA Expression of HuT78 Cells Resulting From the HIV-1 Viral Protein R R77Q Mutation , Joshua S. Ramsey

Theses/Dissertations from 2022 2022

Biofilm Characterization and the Potential Role of eDNA in Horizontal Gene Transfer in Hospital and Meat Isolates of Staphylococcus aureus and Their Biofilms , Ashley Lynne Ball

Novel Patterns for Nucleosome Positioning: From in vitro to in vivo , David Andrew Bates

The Effects of Polymorphisms of Viral Protein R of HIV-1 on the Induction of Apoptosis in Primary Cells and the Characterization of Twelve Novel Bacillus anthracis Bacteriophage , Jacob D. Fairholm

Analysis of the Cytopathogenic Effect of Different HIV-1 Vpr Isoforms on Primary Human CD4+ T Cells and a Model Cell Line , Jonatan Josue Fierro Nieves

The Role of Chitinase A in Mastitis-Associated Escherichia coli Pathogenesis , Weston D. Hutchison

Big Data Meta-Analyses of Transcriptional Responses of Human Samples to Orthohantavirus Infection and Shotgun Metagenomics From Crohn's Disease Patients. , John L. Krapohl

An Exploration of Factors that Impact Uptake of Human Papillomavirus Vaccines , David Samuel Redd

Genomic Analysis and Therapeutic Development of Bacteriophages to Treat Bacterial Infections and Parasitic Infestations , Daniel W. Thompson

The Use of Nucleotide Salvage Pathway Enzymes as Suitable Tumor Targets for Antibody-Based and Adoptive Cell Therapies , Edwin J. Velazquez

Comparative Sequence Analysis Elucidates the Evolutionary Patterns of Yersinia pestis in New Mexico over Thirty-Two Years , M. Elizabeth Warren

Regulation of T Cell Activation by the CD5 Co-Receptor and Altered Peptides, Characterization of Thymidine Kinase-Specific Antibodies, and Integrating Genomics Education in Society , Kiara Vaden Whitley

Theses/Dissertations from 2021 2021

Evolution and Selection: From Suppression of Metabolic Deficiencies to Bacteriophage Host Range and Resistance , Daniel Kurt Arens

Identifying Sinorhizobium meliloti Genes that Determine Fitness Outcomes , Alexander B. Benedict

Pushing the Limits of SARS-CoV-2 Survival: How SARS-CoV-2 Responds to Quaternary Ammonium Compounds and Wastewater , Benjamin Hawthorne Ogilvie

Mutations in HIV-1 Vpr Affect Pathogenesis in T-Lymphocytes and Novel Strategies to Contain the Current COVID-19 Pandemic , Antonio Solis Leal

Theses/Dissertations from 2020 2020

Staphylococcus aureus Metal Acquisition in Milk and Mammary Gland Tissue , Shalee Killpack Carlson

Antimicrobial Peptide Development: From Massively Parallel Peptide Sequencing to Bioinformatic Motif Identification , Alexander K. Erikson

A Comparison of Chikungunya Virus Infection, Dissemination, and Cytokine Induction in Human and Murine Macrophages and Characterization of RAG2-/-γc-/- Mice as an Animal Model to Study Neurotropic Chikungunya Disease , Israel Guerrero

The Effects of Immune Regulation and Dysregulation: Helper T Cell Receptor Affinity, Systemic Lupus Erythematosus and Cancer Risk, and Vaccine Hesitancy , Deborah K. Johnson

Identification of Genes that Determine Fitness, Virulence, and Disease Outcomes in Mastitis Associated Eschericia coli , Michael Andrew Olson

Theses/Dissertations from 2019 2019

Investigation of Thymidine Kinase 1 in Cancer Progression , Eliza Esther King Bitter

Ribosomally Synthesized and Post-Translationally Modified Peptides as Potential Scaffolds for Peptide Engineering , Devan Bursey

Bioaerosols Associated with Evaporative Cooler Use in Low-Income Homes in Semi-Arid Climates , Ashlin Elaine Cowger

PAS Kinase and TOR, Controllers of Cell Growth and Proliferation , Brooke Jasmyn Cozzens

Regulation of Immune Cell Activation and Functionby the nBMPp2 Protein andthe CD5 Co-Receptor , Claudia Mercedes Freitas

Characterizing Novel Pathways for Regulation and Function of Ataxin-2 , Elise Spencer Melhado

Interactions Between the Organellar Pol1A, Pol1B, and Twinkle DNA Replication Proteins and Their Role in Plant Organelle DNA Replication , Stewart Anthony Morley

SNFing Glucose to PASs Mitochondrial Dysfunction: The Role of Two Sensory Protein Kinases in Metabolic Diseases , Kai Li Ong

Characterizing the Function of PAS kinase in Cellular Metabolism and Neurodegenerative Disease , Jenny Adele Pape

Isolation, Characterization, and Genomic Comparison of Bacteriophages of Enterobacteriales Order , Ruchira Sharma

Isolation, Genetic Characterization and Clinical Application of Bacteriophages of Pathogenic Bacterial Species , Trever Leon Thurgood

Investigation of Therapeutic Immune Cell Metabolism , Josephine Anna Tueller

Theses/Dissertations from 2018 2018

Innate Immune Cell Phenotypes Are Dictated by Distinct Epigenetic Reprogramming , Kevin Douglas Adams

Bacteriophages for Treating American Foulbrood and the Neutralization of Paenibacillus larvae Spores , Thomas Scott Brady

Methods for Detection of and Therapy for Carbapenem-Resistant Enterobacteriaceae , Olivia Tateoka Brown

The Diversity Found Among Carbapenem-Resistant Bacteria , Galen Edward Card

Exploration of Antimicrobial Activity in Natural Peptides and High-Throughput Discovery of Synthetic Peptides , Emma Kay Dallon

Gut Microbiota Regulates the Interplay Between Diet and Genetics to Influence Insulin Resistance , Jeralyn Jones Franson

The Antimicrobial Properties of Honey and Their Effect on Pathogenic Bacteria , Shreena Himanshu Mody

The Ability of Novel Phage to Infect Virulent Bacillus anthracis Isolates , Hyrum Smith Shumway

Galleria Mellonella as an Alternate Infection Model for Burkholderia Species and a Comparison of Suspension and Surface Test Methods for Evaluating Sporicidal Efficacy , Joseph D. Thiriot

The Clinical Significance of HPRT as a Diagnostic and Therapeutic Biomarker for Hematological and Solid Malignancies , Michelle Hannah Townsend

Biomarker Analysis and Clinical Relevance of Thymidine Kinase 1 in Solid and Hematological Malignancies , Evita Giraldez Weagel

Hospital and meat associated Staphylococcus aureus and Their Biofilm Characteristics , Trevor Michael Wienclaw

Theses/Dissertations from 2017 2017

Comparison of Cytokine Expression and Bacterial Growth During Periparturient and Mid Lactation Mastitis in a Mouse Model , Rhonda Nicole Chronis

Influence of Epstein-Barr Virus on Systemic Lupus Erythematosus Disease Development and the Role of Depression on Disease Progression , Caleb Cornaby

The Effects of Nucleosome Positioning and Chromatin Architecture on Transgene Expression , Colton E. Kempton

Phosphate Signaling Through Alternate Conformations of the PstSCAB Phosphate Transporter , Ramesh Krishna Vuppada

Acetobacter fabarum Genes Influencing Drosophila melanogaster Phenotypes , Kylie MaKay White

Theses/Dissertations from 2016 2016

The Path to Understanding Salt Tolerance: Global Profiling of Genes Using Transcriptomics of the Halophyte Suaeda fruticosa , Joann Diray Arce

Genetic and Biochemical Analysis of the Micrococcin Biosynthetic Pathway , Philip Ross Bennallack

Characterizing Interaction Between PASK and PBP1/ ATXN2 to Regulate Cell Growth and Proliferation , Nidhi Rajan Choksi

The Activity of Alkaline Glutaraldehyde Against Bacterial Endospores and Select Non-Enveloped Viruses , Justen Thalmus Despain

The Role of Viral Interleukin-6 in Tumor Development of Kaposi's Sarcoma-Associated Herpesvirus Lymphomas , Rebecca A. Fullwood

The Role of the Transcriptional Antiterminator RfaH in Lipopolysaccharide Synthesis, Resistance to Antimicrobial Peptides, and Virulence of Yersinia pseudotuberculosis and Yersinia pestis , Jared Michael Hoffman

A CryAB Interactome Reveals Clientele Specificity and Dysfunction of Mutants Associated with Human Disease , Whitney Katherine Hoopes

The pmrHFIJKLM Operon in Yersinia pseudotuberculosis Enhances Resistance to CCL28 and Promotes Phagocytic Engulfment by Neutrophils , Lauren Elizabeth Johnson

Characterization of Five Brevibacillus Bacteriophages and Their Genomes , Michael Allen Sheflo

Analysis of Nucleosome Isolation and Recovery: From In Silico Invitrosomes to In Vivo Nucleosomes , Collin Brendan Skousen

Human Herpesvirus 6A Infection and Immunopathogenesis in Humanized Rag2 -/-γc-/- Mice and Relevance to HIV/AIDS and Autoimmunity , Anne Tanner

Theses/Dissertations from 2015 2015

Identifying and Characterizing Yeast PAS Kinase 1 Substrates Reveals Regulation of Mitochondrial and Cell Growth Pathways , Desiree DeMille

The Detection and Molecular Evolution of Francisella tularensis Subspecies , Mark K. Gunnell

Isolation and Host Range of Staphylococcus aureus Bacteriophages and Use for Decontamination of Fomites , Kyle C. Jensen

The Antioxidant and DNA Repair Capacities of Resveratrol, Piceatannol, and Pterostilbene , Justin Ryan Livingston

High Salinity Stabilizes Bacterial Community Composition and Activity Through Time , Tylan Wayne Magnusson

Advancing Phage Genomics and Honeybee Health Through Discovery and Characterization of Paenibacillaceae Bacteriophages , Bryan Douglas Merrill

Specialized Replication Operons Control Rhizobial Plasmid Copy Number in Developing Symbiotic Cells , Clarice Lorraine Perry

Gene Networks Involved in Competitive Root Colonization and Nodulation in the Sinorhizobium meliloti-Medicago truncatula Symbiosis , Ryan D. VanYperen

Theses/Dissertations from 2014 2014

Snf1 Mediated Phosphorylation and Activation of PAS Kinase , Bryan D. Badal

Studies of PhoU in Escherichia coli: Metal Binding, Dimerization,Protein/Protein Interactions, and a Signaling Complex Model , Stewart G. Gardner

Pharmacologic Immunomodulation of Macrophage Activation by Caffeine , Ryan Perry Steck

Analysis of Nucleosome Mobility, Fragility, and Recovery: From Embryonic Stem Cells to Invitrosomes , Ashley Nicolle Wright

Enhancing Protein and Enzyme Stability Through Rationally Engineered Site-Specific Immobilization Utilizing Non-Canonical Amino Acids , Jeffrey Chun Wu

Theses/Dissertations from 2013 2013

Thymidine Kinase 1: Diagnostic and Prognostic Significance in Malignancy , Melissa Marie Alegre

Promoter Polymorphisms in Interferon Regulatory Factor 5 , Daniel N. Clark

Modulators of Symbiotic Outcome in Sinorhizobium meliloti , Matthew B. Crook

Evidences for Protein-Protein Interactions Between PstB and PhoU in the Phosphate Signaling Complex of Escherichia coli , Kristine Dawn Johns

Identification of the Binding Partners for HspB2 and CryAB Reveals Myofibril and Mitochondrial Protein Interactions and Non-Redundant Roles for Small Heat Shock Proteins , Kelsey Murphey Langston

A Quadruplex Real-Time PCR Assay for the Rapid Detection and Differentiation of the Burkholderia pseudomallei Complex: B. mallei , B. pseudomallei , and B. thailandensis , Chinn-woan Lowe

The Role of Nuclear BMP2 in the Cell Cycle and Tumorigenesis , Brandt Alan Nichols

Nuclear BMP2 and the Immune Response , Daniel S. Olsen

Hypersaline Lake Environments Exhibit Reduced Microbial Dormancy , Joshua Christopher Vert

Theses/Dissertations from 2012 2012

Characterization of the Cellular and Organellar Dynamics that Occur with a Partial Depletion of Mitochondrial DNA when Arabidopsis Organellar DNA Polymerase IB is Mutated , John D. Cupp

Effect of Antioxidants and Oxidative Stress on Different Cancer Cell Types , Gaytri Devi Gupta Elera

Effects of Chemical Stimulation and Tumor Co-Incubation on Macrophage Activation and Aggressiveness, Measured Through Phagocytosis and Respiratory Burst , Bo Marcus Gustafsson

Loss of the Lipopolysaccharide Core Biosynthesis rfaD Gene Increases Antimicrobial Chemokine Binding and Bacterial Susceptibility to CCL28 and Polymyxin: A Model for Understanding the Interface of Antimicrobial Chemokines and Bacterial Host Defense Avoidance Mechanisms , Cynthia S. Lew

Partial Characterization of the Antimicrobial Activity of CCL28 , Bin Liu

Characterizing the Role of HspB2 in Cardiac Metabolism and Muscle Structure Using Yeast and Mammalian Systems , Jonathan Paul Neubert

Humanized Mice as a Model to Study Human Viral Pathogenesis and Novel Antiviral Drugs , Freddy Mauricio Sanchez Tumbaco

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Department of Biotechnology and Food Science

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Phd theses - department of biotechnology and food science.

• Analysis and Control of Microbial Systems
• Biopolymers and Biomaterials
• Food Science
• Microbial Biotechnology

• MS Biotechnology (thesis)
• Graduate Programs

The Master’s of Science in Biotechnology program in the College of Medicine will prepare students to function in the industrial biotechnology environment. This program is designed to give students broad knowledge and training in the scientific and practical aspects of biotechnology.

It involved innovative, hands-on and multidisciplinary learning approaches to educate and train students in scientific aspects of biotechnology. The courses and research training required of all students in this program are designed to develop independent thinking, team work and communication skills, which are highly desirable in the biotechnology industry.

Students will be provided an industrial perspective and an understanding of product development at the same time as they are trained in the biotechnology techniques required for such development.

The Master’s of Science in Biotechnology program consists of a minimum of 30 semester credit hours of graduate courses offered by the College of Medicine that includes 21 credit hours minimum of required courses, at least two graduate seminar courses, three credit hours of restricted electives, and six credit hours of thesis research.

Total Credit Hours Required

30 credit hours minimum beyond the Bachelor’s Degree

Thesis Proposal

Students must successfully complete a thesis proposal defense no later than the end of the summer of the first year in the program. The oral thesis defense will consist of a 50 minute presentation of thesis work, a 10 minute free period for questions, and a one hour closed-door examination.

Comprehensive Examination

Students must pass an oral comprehensive examination to test understanding of basic concepts in this field no later than the end of the summer of the first year in the program.

Thesis Defense

An oral thesis defense is required for this program. A final thesis, which consists of a manuscript ready for submission to a journal, but prepared in a thesis format, is required before scheduling the thesis defense. Approval of the final thesis will require consent from the majority of the Thesis Advisory Committee.

Graduates are prepared for careers as:

• Medical Researchers
• Research Scientist
• USDA Research Scientist
• Forensic Technologist
• Laboratory Technicians/ Medical Technicians
• High School/ Community College Teachers
• Biotechnology Industry jobs
• Hospital/Clinical Technicians
• Research Foundation Technologists

Application Requirements

• General UCF graduate application requirements
• One official transcript (in a sealed envelope) from each college/university attended
• Three letters of recommendation
• A written statement of research experience, area of interest, and immediate and long-range goals
• Minimum TOEFL score (if applicable)

Applicants who hold a Bachelor’s degree in unrelated fields are expected to have the equivalent of 16 semester hours of credit in the biotechnology/biological sciences including a course in general microbiology, biochemistry of molecular biology or cell biology, plus one year of organic chemistry, one year of physics, basic university mathematics and statistics, and laboratory skills equivalent to the minimum required of our own undergraduates.

In the Master’s of Biotechnology Thesis track, students may receive financial assistance through fellowships, assistantships, tuition support, or loans. Financial awards are based on available funds and academic merit to highly qualified students.

• Tuition fully covered
• Stipend: $16,000–$20,000/year
• Health Insurance covered

For more information, please visit the graduate catalog here

View the program handbook here

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Master in Biotechnology

Master's thesis.

The master's degree programme concludes with a master's thesis of 35 weeks duration that includes a written report and oral presentation. The topic of the thesis can be chosen according to the student's interests in the field of biotechnology.

The master's thesis must be completed in a different group or company department - and supervised by a different professor - than the research project/internship!

Students completing the master's thesis at ​BSSE: in addition to the registration via myStudies, you are required to inform the Department Administration about your stay at least 2 weeks before the scheduled start via the external page Registration Form .

Home > SSE > BIOTECH > BIOTECH_ETD

Biotechnology Program Theses and Dissertations

Theses/dissertations from 2025 2025.

Functional Dissection of the Periplasmic Domain of RcsD, the Phosphotransfer Protein of Escherichia Coli Rcs System , Abdelraouf Dapour

The Role of GSK-3α Inhibition in Attenuating LPS-Induced Inflammation in RAW 264.7 Cells , Oluwaseyi Oyewole

Theses/Dissertations from 2024 2024

Investigating the Association Between Gut Bacteria and Childhood Neuropsychiatric Disorders , Maha Abdo

Cytotoxicity, Antibacterial and Anti-Inflammatory Properties of A Synthesized Curcumin Analog and One of Its Novel Derivatives , Marian Amir

Integrative Genomic Insights into Coral Resilience: Adaptive and Acclimatory Responses to Seasonal Environmental Shifts , Tasnim Ghanim

Can miRNA be the Missing Link Between Parkinson’s Disease and Pesticides? , fatma gobba

Antibacterial and Anticancer Activities of a Fosmid Clone from Atlantis II Red Sea Brine Pool. , Marina Nabil

Deciphering the Microbial Fingerprint of COVID-19: A Multi-Layered Exploration of the Oral and Gut Microbiome Dysbiosis , Iman Mostafa Sultan

Theses/Dissertations from 2023 2023

Preparation and Characterization of Salvia triloba Extract and Evaluation of Its Cytotoxic Effect on Bone Cancer Cell Line , Basma Hossam Abdelmonem

Computational Identification of Circulating MicroRNAs Associated with the Early Stage of Ovarian Cancer , Ahmed Abdelrahman El Hosseiny

Cytotoxic Activity of Salvia Officinalis Extract Mediated by the Inhibition of JAK2 in Breast Cancer , Salma Alawadi Dawood

Plastivore: Identification and Functional Characterization of Plastic Degrading Lipase and Carboxylesterase Enzyme Families from Galleria mellonella , Joseph Boctor

Terfezia Boudieri and Terfezia Claveryi Inhibit the LPS/IFN-γ-Mediated Inflammation in RAW 264.7 Macrophages Through an Nrf2-Independent Mechanism , Abdelhameed Dawood

Metaproteomics Profiling of Gut Microbiota in Pediatric Acute Lymphoblastic Leukemia Patients , Shahd Ezz El Din

Sperm DNA Integrity in Absolute Teratozoospermia Patients and its Impact on Assisted Reproductive Technology Outcome , Dina Faris

Association of Gut Microbiota Composition with Alzheimer’s-Like Disease in A Rat Model , Hana Heiba

A Review of COVID-19 Lockdown Across Different Countries During 2020: Characterization of Risk Factors and Severity of COVID-19 in Egyptian Patients , Hanya Mohamed

Targeting the Warburg and Q Effect: Novel Strategy to Disrupt Cancer Metabolism , Mahmoud Adel Mohamed

Molecular Diagnosis of Non X-linked Ectodermal Dysplasias Using Next Generation Sequencing , Eman AbdelAlim Rabie

Effects of Date Seed (Phoenix dactylifera) Extract in an Animal Model of Diabetes Mellitus , Sara Refaat

Neuroprotective Effects of Green Tea (Camellia Sinensis) and Broccoli (Brassica Oleracea) Extracts in an In Vitro Model of Multiple Sclerosis , Sara Taha Fathallah

Metabolomics Unveiled: Decoding Platelet Dynamics in Smokers, and Head-Neck Cancer Patients , Anthony Nasr Tanios

Theses/Dissertations from 2022 2022

A Predictive Model for Geographical Location Using Microbiome Composition and COVID-19 Based Analysis , Ahmed Adel Aboushanab

Characterization of Testis-Derived Mesenchymal Cells and the Hunt for Universal Stemness Markers , Myret Ghabriel

Knockdown of MDM2 in HepG2 Cell Line: A Step Towards Understanding the Relation Between miRNA590-3p and its Downstream Target Gene, MDM2, in Hepatocellular Carcinoma , Jihad Mahmoud

MiRNAs levels in a Streptozocin model of Alzheimer’s disease , Nada Moustafa

Selective GSK3β inhibition mediates an Nrf2-independent anti-inflammatory microglial response , Mohamed H. Yousef

Theses/Dissertations from 2021 2021

Optimization of In-Vitro Tissue Culture and Transformation System for Sweet Sorghum Cultivars Using Immature Inflorescence , Logayn Abushal

Identifying MicroRNAs Panel Associated With Hepatocellular Carcinoma in Serum of Chronic Hepatitis C Patients , Areeg Dabbish

Analysis of Single Cell RNA-seq Data Revealed Interferon Gamma Signaling Alteration in Severe COVID patients , Ahmed Elbaz

Herbal Extracts as Neuroprotective Agents in an In-vitro Model of Aluminum Neurotoxicity , Nada Ezzelarab

Anti-angiogenic effects of chemotherapeutic agents and their enhancement with OT-515 and S-NACH , Shimaa Adel Heikal

Autophagic Reprogramming of Bone Marrow-Derived Macrophages , Mayada Mahmoud Zaki Mohamed Mazher

Autophagic Reprogramming of Macrophages Polarization , Mayada Mahmoud Zaki Mohamed Mazher

Evaluation of the Anticancer Potential of Alchemilla vulgaris Extract Against Human Neuroblastoma Cells , Yomna Moqidem

Role of Ataxia Telangiectasia Mutated in the Repair of Magnetite Nanoparticles Induced Double Strand Breaks Associated with Heterochromatin , Mie Mohamed Mounir

Assessment of the Potential Anti-tumour Effect of Salvia triloba and the Combination of Salvia triloba and Paclitaxel on Ovarian Cancer: SKOV3 Cell Line , Naela Saleh

Insights Into Halophilic Microbial Adaptation: Analysis of Integrons and Associated Genomic Structures and Characterization of a Nitrilase in Hypersaline Environments , Sarah Sonbol

Mining Selected Metagenomes/metatranscriptomes for Biosynthetic Gene Clusters and Antimicrobial Resistance Genes , Ahmed Yamany

Theses/Dissertations from 2020 2020

Evaluation of the cytotoxic effect of Salvia triloba on Osteosarcoma (U2OS) cell line , Rowan Bahaa El-din Abd El-bary

The crosstalk between COBRA1 and Wnt/β-catenin signaling in cervical cancer , Omnia Mahmoud Abdelraheem

A patient-specific adaptation of the Living Human Heart Model in application to pulmonary hypertension , Yousof Abdel-Raouf

Analysis of single-cell RNA-Seq reveals dynamic changes during macrophage state transition in atherosclerosis mouse model , Ahmed Safwat Abouhashem

The anti-diabetic potential of the African Adansonia Digitata L. plant extract , Marwa Tawfik Badawy

In-depth analysis of culturable microalgae diversity in the river Nile at different locations , Amal Abouel-Fetouh Badr

Expression Levels of miR-590-3p in Hepatocellular Carcinoma and Osteosarcoma Cell Lines and its Downstream Target Genes , Mennatallah Mohamed Bassem Mahmoud Elfar

Fabrication and characterization of polycaprolactone-based nanofibrous scaffolds for neuronal tissue regeneration , Manar Ahmed Elnaggar

Profiling Genome-Wide DNA Methylation Patterns in Human Aortic and Mitral Valves , Sarah Halawa

Role of Ataxia Telangiectasia mutated in the repair of Magnetite Nanoparticles induced double strand breaks associated with Heterochromatin , Mie Mohamed Mounir

Circulating microRNAs in neuromuscular disorders , Nahla Mousa

Assessment of forage quality Among the sudangrasses, sweet and grain sorghum inbred lines at different cutting time points , Muziri Mugwanya

Novel DNA ligases from the Red Sea brine pools: Cloning, expression, in silico characterization and comparative thermostability , Iyanu Mumeen Oduwole

Role of microRNA-208a as a diagnostic and prognostic marker in patients with ST-elevation myocardial infarction , Abou bakr Mohamed Mohamed Hammad Salama

MiR-590-3p suppresses cellular migration and clonogenicity and epithelial to mesenchymal transition in the HepG2 cell line by targeting MDM2 and SETD7 , Alaa Youssef

Theses/Dissertations from 2019 2019

Modulation of stress response in Rice via genome editing of splicing factors , Dina Abou-Raiya

Fabrication of pomegranate peel extract/honey nanofibers loaded with bee venom as effective antibacterial wound dressings , Sara Abouzekry

Direct conversion of mouse fibroblasts into osteoblasts and investigating COBRA1 expression responce , Walid Almoafy Alasar

Identification, expression and biochemical characterization of AMP phosphorylases from extreme environments , Noha Attallah

Novel antimicrobial peptide with anticancer properties , Sheri Magdy Saleeb Bakheit

Predictions and Computational Analysis of Novel Chromosomal Type II Toxin Antitoxin Systems in the Human Oral Microbiome , Ashraf Abd-el-Raouf Bazan

Fabrication of layer-by-layer ECM/polysaccharides/electrospun composite nanofibrous scaffolds and hydrogels for in-vitro skin cell regeneration , Fatma Nabil El-Shishiny

Evaluating the bioactivity and biocompatibility of nylon coated ultra-high molecular weight polyethylene (UHMWPE) , Nancy Hassanein

Molecular and Functional dissection of IgaA, the negative regulator of the E.coli Rcs system. , Nahla A. Hussein

Growth factor-free and antimicrobial elastic nanocomposites for bone regeneration , Dina Mohsen Ibrahim

The effect of Ephedra foeminea on human bone osteosarcoma U2OS cell viability and migration , Eric Zadok Mpingirika

Genetic diversity comparison among invasive fish populations (Nemipterus randalli and Serranus cabrilla) from Mediterranean and Red Sea coastal waters using cytochrome c oxidase subunit I (COI) , Joel Ogwang

Turmeric/ Oregano extracts as wound healing agents in a diabetic animal model , Diana Guirguis Sami

Mining for specialized metabolism genes in Red Sea brine pool prokaryotic metagenomes for antibacterial and anticancer activities , Laila Ziko

Theses/Dissertations from 2018 2018

HeLa cell line, a model to study the role of cofactor of BRCA1 in cervical cancer , Noha Saad Abd Elhamied

The interplay of genetic variation and regulation of long noncoding RNAs in colorectal cancer , Amany Abdel-Motaleb

Evaluating the efficacy of liposomal delivery of nedaplatin in enhancing cytotoxicity, genotoxicity and DNA damage in lung, breast, and osteosarcoma cancer cell lines , Salma Abdelnaser

Therapeutic potential of curcumin in a spinal cord injury model: Local application versus dietary supplement , Sarah Kamel Farahat Abu hussein

Evaluation of cytotoxic potential of loratadine and the combination of loratadine and cisplatin on hepatocellular carcinoma cell lines , Nouran Adly

Mining the red sea metagenomics libraries for betaine pathways , Sherouk Allam

The effect of adding radiotherapy to the administrated chemotherapy on infants' gut microbiome , Nourhan Elsahly

Cytotoxic activity of the Red Sea anemone entacmaea quadricolor on liver cancer cells , Noha Moataz El Salakawy

Cofactor of BRCA1 promotes epithelial-mesenchymal transition and cell proliferation in intermediate stage hepatocellular carcinoma cell line , Mennatallah Ghouraba

Prevalence and determinants of self-medication with antibiotics in high and low-income areas within Cairo , Shaymaa Mohamed Hassan

Expression analysis of liver-specific circulating micrornas in hcv-induced hepatocellular carcinoma in Egyptian patients , Lobna Mohamed Mourad

Theses/Dissertations from 2017 2017

MicroRNAs as noninvasive biomarkers for the diagnosis and prognosis of liver fibrosis in HCV genotype 4 patients , Amanda Abdel-Al

Development of immuno- nanoparticles for targeting schistosoma parasites , Eman Rabie Abdul-Ghany

Virome of red sea brine pools and other hydrothermal vents , Sherry Kamal Berty Aziz

Impacts of exposure to low concentration of titanium dioxide nanoparticles on cell cycle control and DNA repair in normal, cancer and DNA repair deficient cells. , Nada EL Zahed

Transcriptional response to stressors in arabidopsis thaliana , Aya Abd Elsalam Galal

Analysis of the thermal stability of mercuric reductase from the hot brine environment of Atlantis II in the Red Sea by site-directed mutagenesis: Structural interpretation of thermolabile and enhanced thermostable mutants , Mohamad Maged Galal

Translational profiling of adipocytes within adipose depots and intermuscular adipose tissues , Sara Serag Hassan

Induced pluripotent stem cells derived from mouse germ cells , Nora Khan

Characterization of aggresome formation in choroid plexus carcinoma. , Marwa Mohamed Ali Nassar

Mannose binding lectin in the treatment of imiquimod induced psoriasis mouse model , Hagar Nofal

Molecular adaptation of mercuric reductase to hypersaline environments , Emanbellah Ramadan

Theses/Dissertations from 2016 2016

In silico screening, analysis, and modelling for a novel anticancer peptide , Youssef Abdou

Genome-wide transcriptomic analysis of alternative splicing modulation in Arabidopsis thaliana , Moustafa Ahmed Abohawya

Transcriptomic profiling of the extremophile eutrema salsugineum response to environmental stressors , Diana Abou El Hassan

Analysis of the D1S80 VNTR locus polymorphism in the Nubian population , Soha Rabie Ahmed

Antibiotic resistance in Red Sea brine pools , Ali Hassan Ali Elbehery

Calcified gelatin nanofibers for guided tissue regeneration using water-based benign solvent: An investigation for periodontal applications , Nihal Abdelnabi Elsayed

In silico identification and in Vitro assessment of a potential anticancer peptide sequence retrieved from the red sea metagenomics library , Mona Elradi Imam

Overexpression of cofactor of BRCA1 in HepG2 cells: A step towards understanding the role of COBRA1 in hepatocellular carcinoma , Razan Jamil Masad

The microbiome of The Egyptian Red Sea proper and Gulf of Aqaba , Ghada Alaa El-Din Mustafa

Regulatory networks in non-small cell lung cancer: Connecting differentially expressed genes, miRNAs, and incRNAs , Jasmine Omran

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Master Theses and Research Internships during summer or winter semester

Are you interested to do your master project or a research internship in one of the world-wide leading protein engineering labs? We always offer individual master theses or research internships within our research fields. The direct supervision in the lab is ensured usually by a PhD fellow or a post doc who works in the chosen field of research. The duration of a master thesis is usually six months in full-time, a research internship takes about six to eight weeks in full-time. Both master theses and research internship reports may be written in consultation with the supervisors and examiners in either German or in English.

If we awoke your interest to do your master thesis or a research internship in our institute, please write an e-mail to our secretary Corina Barth with a short letter of motivation, curriculum vitae and certificates or contact directly one of our division leaders in case of specific interests. You can also have a look at the advertised open projects but please consider that not all open projects are advertised on our homepage. After receipt of you short application you'll get a feedback within two weeks.

last updated: 17/08/2022

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• SeSaM Biotech

The Fall 2025 Application will open October 1

Ms in biotechnology.

Biotechnology is fueling advancements in healthcare and beyond. Prepare for the business or science side of this fast-growing field with the comprehensive MS in Biotechnology program at Johns Hopkins University.

MS in Biotechnology Program Overview

Life sciences. Technology. Business.

Biotechnology is about making discoveries that make the world a better place, and about bringing those concepts to life… and into the market. Spanning industries, including pharmaceuticals, agriculture, healthcare, environment, energy, national security, biotechnology covers roles from the R&D lab, product development, and manufacturing to sales, marketing, finance, and law.

This robust graduate program at Johns Hopkins University offers concentrations and elective courses that result in a degree designed to fit your career aspirations.

Study on Your Terms

Designed for both part-time and full-time students, this biotechnology master’s program offers you the flexibility to take classes online or on-campus in the evenings and on weekends.

What It’s Like to Study Biotechnology at AAP

In-Depth Article

Biotechnology Master’s Degree: Career Opportunities & Paths

Biotechnology offers diverse career opportunities ranging from agriculture to healthcare to national security. A master’s in biotechnology can advance your career, allow you to explore new fields, and make a positive impact on the world.

Upcoming Events

Biotechnology Community Social Hour

Ms in regulatory science information session, master of biotechnology enterprise and entrepreneurship info session, ms in bioinformatics information session.

The program provided a solid foundation in biodefense, both from a historical and present-day perspective and has proved invaluable to me in my current position.

Why to Pursue an MS in Biotechnology at Hopkins

Learn From Leading Researchers

Exciting things are happening in the biotechnology labs at Johns Hopkins. You’ll learn from experts who are actively researching, making discoveries, and publishing in an evolving field.

Explore Concentrations and Courses

Customize your program with electives based on your professional and scientific interests. You may also concentrate in one of six areas, including biodefense, regulatory affairs, or drug discovery.

Join a Diverse, Successful Scientific Community

When you enroll at Johns Hopkins, you become part of an international community of biotechnology, research, and medical professionals who work in labs, universities, and companies around the world.

Share Your Discoveries: The Research Symposium

Each May our graduate students are invited to showcase their independent research. The annual event features poster presentations, a notable guest speaker, and more.

MS in Biotechnology and MBA Dual Degree

The MS in Biotechnology/MBA is one of the nation’s first and largest dual graduate degree programs in biotechnology and business. The program allows you to earn two advanced degrees in less time than it takes to earn them separately.

Biotechnology News

Take the Next Step

Prepare yourself with the latest knowledge and experiences to excel across the greater biotechnology industry.

Contact Us for More Information

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Top 100 Biotechnology Dissertation Topics for the Year 2021

• September 14, 2021 September 14, 2021

Biotechnology is one of the major streams of science where students request for our reliable and time-tested assignment help from prestigious universities, colleges, and institutes around the globe. The subject helps us understand how we can effectively utilise biological systems, living organisms, or their parts to develop or create different types of products.

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Apart from genetics, bioengineering and research, the subject offers decent career options in industrial sectors like textiles, food, agriculture, pharmaceutical and animal husbandry.

Introduction

Modern biotechnology has been credited with breakthrough innovations in the field of product development and technologies to help us develop a cleaner and more sustainable world. It is primarily because of biotechnology; we have progressed towards the development of more efficient industrial manufacturing base. Besides, it is helping in the production of cleaner energy, feed more hungry people without leaving much of our environmental footprint, and help mankind combat rare and debilitating diseases.

Our assignment writing services in the field of biotechnology cover all types of subject topics that test and vindicate the skill sets of the students before awarding them with their respective degrees. We help students successfully pass their syllabus in all forms of biotechnology courses. These include medical biotechnology (red), environmental biotechnology (green), marine biotechnology (blue) and industrial biotechnology (white).

What are We Expecting to Gain from All these Efforts?

Our sole objective of preparing this marathon list of top 100 biotechnology assignment topics is to help students decide upon effective time management skills. We have seen an immense numbers of cases where while exploring online assignment help related to topic selection, exploration of information sources, and citing them in correct reference order, students get stuck at different stages. Amongst them, most of the students find it difficult even to pass their topic selection dilemma. That is where we contribute to our efforts to make things easy for the biotech students right in one go. We help our students save time and energy, so that they can prudently use the assigned time to prepare the content of their assignment around the best topics.

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Must read: wish to master dissertation skills in 2 weeks learn from the experts here, top 100 biotechnology dissertation topics trending in the year 2021.

We have prepared the list of top 100 most recommended dissertation topics prepared by our research experts. They have ensured to provide a comprehensive list of topics that are covering all the dimensions of the subject. We fully hope that the list would cover all your dissertation help requirements. So, let us begin with the prepared list of topics one by one –

• Effective management of renewable energy technology to promote a village
• The production of ethanol with the help of molasses as well as its effluent treatment
• Different methods and aspects of evapotranspiration
• The scattering parameters of the circulator biotechnology
• The inactivation of the mammalian TLR2 through an inhibiting antibody
• Number of proteins through Mycobacterium tuberculosis
• The recognition and classification of the genes shaping the plant responses to salinity and drought
• The segment of small signing molecules in the responses of plants to salinity and drought
• Genetic improvement of the plant lenience to salinity and drought
• Pharmacogenomics of the drug transporters
• Pharmacogenomics of the anti-cancer drugs
• Pharmacogenomics of the anti-hypertensive drugs
• Indels genotyping of the African populations
• Y-chromosome genotyping of the African populations
• Profiling of the DNA isolated from the historical crime scenes: Discuss in terms of South African Innocence Project
• Nanotechnology methods in terms of DNA isolation
• Nanotechnology applications in terms of DNA genotyping
• Recognizing heavy metal tolerant along with sensitive genotypes
• Features of genes that participate in the process of heavy metal tolerance
• DNA authentication of the animal species through raw meat products reared commercially
• Molecular based technology in terms of rapid identification and detection of the food borne pathogens with respect to complex food systems
• Making an assessment of cancer specific peptides for successful implementations in the field of cancer diagnosis
• Quantum dot-based detection system development with respect to successful breast cancer diagnosis
• Targeted delivery of the embelin to the cancer cells
• Accessing the role of novel quinone compounds to perform as anti-cancer agents
• Therapeutic approaches to the treatment of HIV and the role of nanotechnology in it
• An assessment of the medicinal value of the natural antioxidants
• An indepth study of the structure of the COVID spike proteins
• An assessment of the immune response of the stem cell therapy
• The use of CRISPR-Cas9 technology for the purpose of genome editing
• Tissue engineering and the drug delivery with the application of Chitosan
• An assessment of therapeutic effects of the cancer vaccines
• Utilization of PacBio sequencing with respect to genome assembly of the model organisms
• Studying the relationship between the mRNA suppression and its impact on the expansion of the stem cell
• Utilizing biomimicry for the identification of the tumor cells
• The sub-classification and characterization of the Yellow enzymes
• The production of the hypoallergenic fermented foods
• The production of the hypoallergenic milk
• The purification process of the thermostable phytase
• Bioconversion of the cellulose to successfully yield the products that are industrially significant
• The examination of the gut microbiota in the model organisms
• The utilization of the fungal enzymes in the production of chemical glue
• An examination of the inhibitors of exocellulase and endocellulase
• Discuss the utility of microorganisms in the recovery of shale gas
• Discuss the in-depth study of the procedure of natural decomposition
• Discuss the process of recycling the bio-wastes
• Enhanced bio-remediation for the cases of oil spills
• The process of gold biosorption with the help of cyanobacterium
• Maintaining a healthy balance between the biotic and the abiotic factors with the help of biotechnological tools
• Labeling the level of mercury in fish with the help of markers
• Exploring out the biotechnological potential of the Jellyfish related microbiome
• What is the potential of marine fungi in the efforts to degrade polymers and plastics?
• Discuss the biotechnological potential that one can fetch out of dinoflagellates
• Tracing out endosulfan residues with the application of biotechnology in the field of agricultural products
• The development of the ELISA technique for the identification of crop viruses
• Boosting the quality of drinking water with the help of E.coli consortium
• The characterization of E.coli isolation from the feces of the zoo animals
• Improving the resistance of the crops against the invasion of the insects
• Reducing the spending on agriculture with the help of effective bio-tools
• What are the most effective steps to reduce soil erosion with the utility of tools derived from biotechnology?
• How biotechnology can help in the improvement the levels of vitamin in GM foods?
• Improving the delivery of pesticide with the help of biotechnology
• Comparing folate biofortification in different kinds of corps
• Discuss the photovoltaic-based production of the ocean crops
• How the application of nanotechnology to improve the activities of the agricultural sector?
• Examining the mechanisms of water stress tolerance in the model plants
• Testing and production of the human immune boosters in the experimental organisms
• Comparing genomic analysis with the utility of tools meant for bioinformatics
• Arabinogalactan protein sequencing and its utility in computational methods
• Evaluating and interpreting gut microbiota in the model organisms
• Different techniques of protein purification: A comparative analysis
• Diagnosing microbes and their role in o ligonucleotide micro-arrays
• The application of different techniques in the field of biomedical research comprising micro-arrays technology
• The application of microbial consortium in producing the greenhouse effect
• Computational assessment of various proteins accessed from marine microbiota
• E.coli gene mapping with the application of various microbial tools
• Enhancing the strains of cyanobacterium with the help of gene sequencing
• Computational assessment and description of the crystallized proteins present in nature
• mTERF protein and its application to terminate the transcription of mitochondrial DNA in algae
• Reverse phase column chromatography and its application in separating proteins
• The study of various proteins present within Mycobacterium leprae
• An assessment of the strategies that are ideally suitable for successful cloning of RNA
• Discuss the common failures of biotechnology in saving the ecology and the environment
• Is there a way to make the medicinal plants free of pests? Discuss
• What are the harms imposed by pest resistant corps on humans and birds?
• What are the diverse fields of biotechnology that still remain unexplored in terms of research?
• What is the future of biotechnology in the field of medicine?
• The application of recombinant DNA technology in the invention of new forms of medicine
• Why is the strain of bacteria used to create vaccine with the help of biotechnology?
• How biotechnology can help in the creation of medicines that are more resistant towards the mutating forms of viruses and bacteria?
• Can there be a permanent cure for cancer in the future? How biotechnology can play a decisive role in it?
• Why it is critical for the students to effectively remember the DNA coding in the field of biotechnology?
• How one can make hybrid seeds with the help from biotechnology?
• How one can generate pest resistant seeds and what are their benefits in the end yielding in agriculture?
• Discuss bio-magnification and its impact on ecology
• What are the reasons due to which the ecologists disapprove the usage of pest resistant seeds, despite their usage in the field of agriculture?
• How biotechnology positively influenced the lives of farmers in the developing economies?
• How biotechnology functions to increase in yield of the crop plants?
• Discuss the role of biotechnology in boosting the output of seasonal crops
• Are there adverse effects of medicines in pharmacology when manufactured with biotechnological principles? Throw some light on the question with real-life cases

Now with that, we have reached the end of this list and fully hope that it would have served the purpose of topic selection requirements. Besides, the inclusion of biotechnology assignment topics has been done in such a manner that it can help us out with our needs related to different other assignment writing formats as well. For instance, all our topic selection requirements related to case study help , essay help , research paper writing help or thesis help can also be met with the topics in the above-mentioned list.

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Must read: top 100 biology dissertation topics for the year 2021.

Biotechnology is a subject that is meant to offer a plethora of research prospects. A successful completion of course in one or more streams of biotechnology will ensure job placement opportunities in different research and development companies dedicated to the field. The objective of recommending this list is to help you make the right topic selection in less amount of time and dedicate more time to assignment research, and adequate content writing. After all, going an extra mile in terms of efforts will ensure that the final submission is good enough to help you earn the grades that can help you beat the competition.

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Biotechnology (MS)

Program at a glance.

• In State Tuition
• Out of State Tuition

Learn more about the cost to attend UCF.

The Master of Science in Biotechnology program in the College of Medicine will prepare students to function in the industrial biotechnology environment. This program is designed to give students broad knowledge and training in the scientific and practical aspects of biotechnology.

It involves innovative, hands-on and multidisciplinary learning approaches to educate and train students in scientific aspects of biotechnology. The courses and research training required of all students in this program are designed to develop independent thinking, teamwork and communication skills, which are highly desirable in the biotechnology industry. Students will be provided an industrial perspective and an understanding of product development at the same time as they are trained in the biotechnology techniques required for such development.

What makes this program unique is the focus on practical training offered to graduate students through master's thesis research in molecular biotechnology to perform jobs in a laboratory environment that require scientific talent.

Application Deadlines

• International

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Program Prerequisites

A bachelor's degree in Biological Sciences or related area.

Applicants who hold a BS degree in unrelated fields are expected to have the equivalent of 16 semester hours in biological sciences including a course in general microbiology, biochemistry or molecular biology or cell biology, plus one year of organic chemistry, one year of physics, basic university mathematics and statistics, and laboratory skills equivalent to the minimum required of our own undergraduates. Minor deficiencies may be remedied after acceptance by enrollment at the first opportunity in an appropriate course.

Degree Requirements

Required courses.

• MCB5722C - Methods in Biotechnology (4)
• BSC6407C - Laboratory Methods in Molecular Biology (3)
• BSC6432 - Biomedical Sciences I (5)
• BSC6431 - Practice of Biomedical Sciences (3)
• PCB5527 - Genetic Engineering and Biotechnology (3)
• BSC5418 - Tissue Engineering (3)
• MCB6417C - Microbial Metabolism (3)
• PCB5025 - Molecular and Cellular Pharmacology (3)
• PCB5815 - Molecular Aspects of Obesity, Diabetes and Metabolism (3)
• PCB5837 - Cellular and Molecular Neuroscience (3)
• PCB5236 - Cancer Biology (3)
• MCB6273 - Advanced Topics in Infectious Processes (3)
• GMS6860 - Statistics for Biomedical Scientists (3)
• Earn at least 2 credits from the following types of courses: Students will participate in at least two graduate seminar courses that will prepare them for making professional presentations with an emphasis in biotechnology. The courses will involve the participation of speakers from the biotechnology industry with emphasis on an industrial perspective on biotechnology applications and product development. Students can take MCB 6314 two times, OR take MCB 6314 and MCB 6938. MCB 6314 - Industrial Perspectives Seminar (can be taken two times at 1 Credit Hour) OR MCB 6938 1 Credit Hour (Can only be taken once)

Elective Courses

• BSC5436 - Biomedical Informatics : Structure Analysis (3)
• IDS5127 - Foundation of Bio-Imaging Science (3)
• MCB5205 - Infectious Processes (3)
• MCB5208 - Cellular Microbiology: Host-Pathogen Interactions (3)
• MCB5209 - Microbial Stress Response (3)
• MCB5225 - Molecular Biology of Disease (3)
• MCB5415 - Cellular Metabolism (3)
• MCB5505 - Molecular Virology (3)
• MCB6226 - Molecular Diagnostics (3)
• PCB5238 - Immunobiology (3)
• PCB5596 - Biomedical Informatics: Sequence Analysis (3)
• PCB5709C - Laboratory Virtual Simulations in Physiology (3)
• PCB5834C - Advanced Human Physiology (4)
• PCB6528 - Plant Molecular Biology (3)
• PCB6595 - Regulation of Gene Expression (3)
• PCB5838 - Cellular and Molecular Basis of Brain Functions (3)
• PCB5265 - Stem Cell Biology (3)
• ZOO5745C - Neuroanatomical Pathways and their Neurotransmitters (4)
• GEB5516 - Technological Entrepreneurship (3)
• Student may choose: MCB 5932 - Current Topics in Molecular Biology VAR Credit Hours, PCB 5937 - Special Topics: Human Endocrinology 3 Credit Hours, MCB 6908: Independent Study - 1-3 Credit Hours (1–2-page written summary required for elective course approval) Others: If approved by the Graduate Committee
• Earn at least 6 credits from the following types of courses: MCB 6971 Students will take a minimum of six credits of thesis research (MCB 6971) to complete their research and submit their thesis specializing in biotechnology research. Students are expected to have an in-depth discussion with at least three faculty members before choosing a laboratory for thesis research. The student and the Thesis Adviser/Major Professor will jointly recommend an advisory committee comprised of at least three members. The committee composition must reflect expertise relevant to the student's thesis research and must be approved by the Graduate Committee. Students switching to change the composition of the Thesis Advisory Committee must also obtain approval from the Graduate Committee.

Thesis Proposal

• The thesis proposal defense requirement should be met and passed successfully no later than the end of the summer of the first year in the program. Students will not be allowed to register for courses for the Fall semester of their second year until this requirement is fulfilled. Should the student fail, a second opportunity will be provided within 2 weeks of the first attempt. A second failure will result in dismissal from the program. Students will be evaluated on the progress in thesis research by the thesis advisory committee for fall and spring. Two consecutive unsatisfactory evaluations will result in dismissal from the program.

Comprehensive Examination

• Students must pass a comprehensive exam to qualify for the Master of Science degree. Students must successfully pass an oral comprehensive examination to test the understanding of the basic concepts in the field and relevant applications. The Comprehensive Examination will be conducted during the thesis proposal defense. The exam will be administered by the thesis committee. Should the student fail this exam, a second opportunity will be provided within 2 weeks of the first attempt. A second failure will result in dismissal from the program.

Independent Learning

• The required thesis allows the student to engage in independent learning.

Grand Total Credits: 30 - 31

Application requirements, financial information.

Graduate students may receive financial assistance through fellowships, assistantships, tuition support, or loans. For more information, see the College of Graduate Studies Funding website, which describes the types of financial assistance available at UCF and provides general guidance in planning your graduate finances. The Financial Information section of the Graduate Catalog is another key resource.

All students receiving assistantships must enroll full time.

Fellowship Information

Fellowships are awarded based on academic merit to highly qualified students. They are paid to students through the Office of Student Financial Assistance, based on instructions provided by the College of Graduate Studies. Fellowships are given to support a student's graduate study and do not have a work obligation. For more information, see UCF Graduate Fellowships, which includes descriptions of university fellowships and what you should do to be considered for a fellowship.

Department of Applied Sciences and Mechatronics

Master - Biotechnology | Bioengineering

In cooperation with the University of Applied Sciences at Weihenstephan-Triesdorf, Department for Bioengineering , the Munich University of Applied Sciences offers the master's course of study Biotechnology | Bioengineering through the Department of Applied Sciences and Mechatronics.

Summary and Benefits:

• Length of study, three semesters with approximately 20 openings each semester,
• Joint competence of both Munich and Weihenstephan,
• Study may begin in either semester,
• Consecutive master's course of study with strong major concentration,
• Both practical and well-rounded,
• Quality guarantied through small groups,
• Outstanding professional opportunities in the life- sciences,
• Good perspectives in the bioregion of Munich,
• Additional professional qualification in this future oriented sector,
• Concentration on practical application with ties to potential employers,
• Internationally recognized degree: Master of Science (M. Sc.),
• Even greater chances to advance the career, for instance through qualification for upper management,
• The opportunity to write a Doctoral Thesis is possible upon completion of the M. Sc. through ties to various universities and research institutes in the area of Munich and globally.

The interdisciplinary master's course of study Biotechnology / Bioengineering is focused on the interface between natural and engineering sciences. This course of study not only provides a thorough grounding in biological processes and their technical application, it also offers a wide spectrum of engineering science, the tools and methods which make it possible for graduates to achieve professional success in many career fields. Such fields include the areas of bioprocess technology, bio-medicine and bio-pharmaceuticals.

The interface between the individual areas of research and development, between production marketing as well as sales is becoming ever more important. The integration of complex systems composed of such subsystems in biology, engineering and IT has become increasingly relevant. Graduates of this course of study have the competence to master these complex tasks.

Thanks to a growing need for professionals in the life-sciences sector, this course of study opens the door for graduates to outstanding future oriented careers. The pharmaceutical, chemical and bioengineering sectors as well as the health industries are all markets in need of this program's graduates.

The consecutive graduate level course of study Biotechnology / Bioengineering is primarily intended for above average graduates in the fields of biotechnology and bioengineering who wish to deepen and greatly advance their competence in this future oriented sector.

Application for Study and Registration

The course of study may be begun in either semester. Approximately twenty students are accepted into the program each semester. Eligibility will also be based upon the GPA of the previous university degree.(Numerus Clausus) .

Registration is through the University of Applied Sciences at Weihenstephan-Triesdorf (only in German).

Further information about graduates studies, registration and matriculation as well as the required forms may be had in the office of general study at the University of Applied Sciences at Weihenstephan-Triesdorf.

Please contact Hochschule Weihenstephan-Triesdorf (only in german)

Prerequisites for the Course of Study

• Successful completion of a B.Sc. in the areas of Bioengineering or Biotechnology at either the Munich University of Applied Sciences or Weihenstephan-Triedsdorf or a comparable such B.Sc.
• A GPA of at least 'good' (please contact the Office of General Studies, below).
• A Completion of a practical internship semester in the undergraduate program or at least eighteen weeks of work in qualifying fields in the industry.
• Foreign applicants whose mother tongue is other than German must demonstrate adequate knowledge of the German language to complete the study successfully.

The regulations and guidelines of the universities as well as the examination board determine all conditions and prerequisites to be admitted to study.

Study objective

The objective of this graduate course of study is to provide graduates with both fundamental knowledge in the central areas of the engineering and life-sciences as well as solid acquaintance with a wide spectrum of technical applications and practice oriented experience.

Alongside the comprehensive study of technology, students are also provided with the knowledge to take on executive positions through a thorough grounding in the science of management as well as a well-rounded basis in the professions of the natural sciences. This can lead to promotion and career success on many levels

Course of study

The Master's Course in Biotechnology / Bioengineering is based on a series of topical and fixed length modules.

The Modules are Composed of Four Groups:

• Required Modules: These modules are to be completed. They comprise the comprehensive foundation for the sector of biotechnology and bioengineering and are the common basis for the course of study.
• Concentration Modules: A catalog of these modules is offered, from which three modules are to be choosen. The student is expected to expand their knowledge through these modules in accordance with their interests and skills.
• Interdisciplinary Modules: A catalog of modules is offered from which one is to be chose. This module serves to provide competence outside of the student's major concentration.
• Sector Specific Modules: A catalog of modules is offered from which one is to be chosen. The modules are drawn from various technologies which are specific to each sector.
• Elective Module: One module is to be chosen from any of the catalogs: Concentration, Interdisciplinary, or Sector Specific.

The third semester is reserved for writing the Master's Thesis.

Further Information about this Master's Course of Study as well as personal assistance at the:

• Prof. Dr. Markus Hilleringmann
• Tel.: (089) 1265 - 1654

University of Applied Sciences Weihenstephan-Triesdorf (HSWT):

• Prof. Dr. Jörg Kleiber
• Tel.: +49 8161 71 4522

The professional opportunities for graduates of the master's course of study Biotechnology / Bioengineering may be considered to be very good. The life-sciences sector, the main branch in which graduates of this course of study will be active, is one of the most modern, dynamic and growing business sectors.

It is worth noting that the area of Munich, wherein this course of study is offered, is one of the most important areas for the biotechnologies in both Germany and Europe. In the year 2009, there were over 22,000 jobs within the field of life-sciences within Bavaria, alone. More than two-thirds within the area of Munich. Additionally, nearly 10,000 professionals are employed in research institutes within this sector throughout Bavaria. It is expected that the number of professionals working in this field will expand considerably in the coming years.

• Examination Board
• Course Catalogue
• Module guide
• Study Regulations (in German)
• Timetable (in German)
• Master's Thesis Registration
• List of previous Thesis (in German)
• Application