hudson medical research institute

• Robert Ian McLachlan

Director of Clinical Research Hudson Institute of Medical Research 27-31 Wright Street, Clayton, Aust 3168

Telephone: (Secretary) 61-3-95943553 Email: [email protected]

  Hudson Institute of Medical Research

Improvement of and setting standards for clinical phenotyping, building structures to collect well-phenotyped patient groups, e.g. based on testicular histology.

Clinical and research interests include male reproductive endocrinology & the evaluation & management of male infertility, and androgen physiology and studies on their use and abuse. He has particular interests in the genetics of male infertility, the optimal use of assisted reproduction and the follow up on ART offspring health.

Kimmins S, Anderson RA, Barratt CLR et al (2023) Frequency, morbidity and equity – the case for increased research on male fertility. Nat Rev Urol.

Handelsman DJ, Grossmann M, Yeap BB et al (2023) Long-Term Outcomes of Testosterone Treatment in Men: A T4DM Post-Randomisation Observational Follow-Up Study. J Clin Endocrinol Metab.

Catford SR, Halliday J, Lewis S et al (2022) The metabolic health of young men conceived using intracytoplasmic sperm injection. Hum Reprod. 37(12):2908-2920.

Catford SR, Halliday J, Lewis S et al (2022) Reproductive function in men conceived with in vitro fertilization and intracytoplasmic sperm injection. Fertil Steril. 117(4):727-737.

Björndahl L, Barratt CLR, Mortimer D et al (2022) Standards in semen examination: publishing reproducible and reliable data based on high-quality methodology. Hum Reprod. 37(11):2497-2502.

Nagirnaja L, Lopes AM, Charng WL et al (2022) Diverse monogenic subforms of human spermatogenic failure. Nat Commun. 13(1):7953

O’Donnell L, Rebourcet D, Dagley LF et al (2021) Sperm proteins and cancer-testis antigens are released by the seminiferous tubules in mice and men. FASEB J. 35(3):e21397.

Catford SR, Lewis S, Halliday J, et al (2020) Health and fertility of ICSI-conceived young men: study protocol. Hum Reprod Open.

Novakovic B, Lewis S, Halliday J, et al (2019) Assisted reproductive technologies are associated with limited epigenetic variation at birth that largely resolves by adulthood. Nat Commun 10:3922.

Catford SR, McLachlan RI, O’Bryan MK, Halliday JL (2017) Long-term follow-up of intra-cytoplasmic sperm injection-conceived offspring compared with in vitro fertilization-conceived offspring: a systematic review of health outcomes beyond the neonatal period. Andrology 5:610–621.

Catford SR, McLachlan RI, O’Bryan MK, Halliday JL (2018) Long-term follow-up of ICSI-conceived offspring compared with spontaneously conceived offspring: a systematic review of health outcomes beyond the neonatal period. Andrology 6:635–653.

Oud MS, Ramos L, O’Bryan MK, et al (2017) Validation and application of a novel integrated genetic screening method to a cohort of 1,112 men with idiopathic azoospermia or severe oligozoospermia. Hum Mutat 38:1592–1605.

Catford SR, O’Bryan MK, McLachlan RI, et al (2019) Germ cell arrest associated with aSETX mutation in ataxia oculomotor apraxia type 2. Reprod Biomed Online 38:961–965.

2017-2021 Australian NH&MRC Project Grant #GNT1120356 (CIB) The genetic causes of male infertility

2020-2024 Australian Medical Research Future Fun [MRFF] Emerging Priorities and Consumer Driven Research initiative EPCD000007 Men and Infertility over the life course (MAIL) CIs G Chambers, R McLachlan, J Halliday, M O’Bryan S. Von Saldern $4,600,000

2023-2027 Australian NHMRC Clinical Trials and Cohort Studies GNT2023952 (CID) The use of scrotal cooling to improve semen quality and pregnancy rates within infertile men A$1,165,000

Home » Members » Our Members » Hudson Institute of Medical Research

Hudson Institute of Medical Research

www.hudson.org.au

Hudson Institute of Medical Research is home to more than 450 internationally recognised biomedical researchers and clinician scientists who are dedicated to transforming lives through breakthrough scientific discovery.

With the largest grouping of inflammation researchers in Australia, Hudson Institute has been supporting the global response to the COVID-19 pandemic by rapidly undertaking research to address the dangerous levels of inflammation caused by SARS-CoV-2.

Hudson Institute is located within a major translational research and medical innovation hub in Melbourne’s south-eastern corridor. Our Precinct partners are Monash Health | Monash Children’s’ | Monash Newborn | Monash University.

Hudson Institute has a strong record for research that is highly translational and commercially valuable. In the past three years, the Institute’s business development program has resulted in the spinout of three Biotech companies and a further 40 commercial partnerships with industry.

Principle research areas

• Inflammation
• Infant and child health
• Reproductive health and pregnancy
• Hormones and health.

Director and CEO

Professor Elizabeth Hartland

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Hudson Institute of Medical Research

Hudson Institute is a leading Australian medical research institute recognised internationally for discovery science and translational research into cancer, inflammation, reproductive health and children's health.

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How much creatine is needed for optimal baby growth?

The role of creatine in healthy pregnancies is well established, but how much is enough? A study at Hudson Institute of Medical Research has shown what's needed to ensure healthy growth of your baby.

Jul 18, 2024

Researchers develop new technique for diagnosing disorders of sex development

Disorders/differences of sex development (DSD) are difficult to diagnose because of the multiple phenotypes and genes involved, but a new technique developed at Hudson Institute of Medical Research is set to change all that.

Genetic changes identified as key to childhood lupus

Australian and Chinese researchers have jointly discovered a genetic key to the development of the devastating autoimmune condition childhood lupus.

Jun 3, 2024

Fetal growth restriction found to harm the heart and lungs via the brainstem

Babies affected by fetal growth restriction (FGR) have poor cardiorespiratory control; now Hudson Institute researchers have become the first to show persistent injury in the brainstem of growth-restricted fetuses as the ...

Feb 28, 2024

How does diet before and during pregnancy affect your child?

Every mother wants to have the healthiest child she can, and new research shows that the nutritional status of the mother during pregnancy can affect outcomes for the baby—with male and female offspring affected differently.

Feb 15, 2024

Research finds 'Goldilocks hormone' crucial for male fertility

Correct development of testes in a male fetus—and fertility later in life—depend on a crucial hormone being at just the right level.

Feb 13, 2024

Controlling inflammation to conquer lung infection

The latest studies at Hudson Institute of Medical Research have identified a novel therapy that controls the body's response to the influenza virus, limiting damaging inflammation and promoting recovery from severe infection.

Jan 16, 2024

Researchers study the link between the bacteria H. pylori and stomach cancer

H. pylori—short for Helicobacter pylori—colonizes the stomach and is known to be linked to the development of stomach cancer. It is estimated that over half of the world's population is infected with H. pylori, making ...

Nov 29, 2023

Hedgehog signaling pathway key in treating osteosarcoma: Study

The strangely named hedgehog pathway that's crucial to bone growth has emerged as a key in the fight to treat the bone cancer osteosarcoma.

Nov 28, 2023

Researchers find a clue to fighting fatal influenza

When influenza (or flu) reaches the critical stage, there are no specific treatments available for patients. Now new research has identified a key to this sometimes fatal condition, and opened the door to possible cures.

Nov 27, 2023

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Hudson Institute

Hudson Institute of Medical Research is a not-for-profit, independent medical research institute which resulted from the 2014 merger of two of Australia’s most trusted names in medical research, Monash Institute of Medical Research (MIMR) and Prince Henry’s Institute (PHI).

The Institute drives innovative research programs through its six specialised research centres (Cancer; Genetic diseases; Immunity, inflammation and infectious diseases; Reproductive Health; Fetal, Neonatal, Children’s and Women’s Health; Endocrinology, and Metabolism) which seek to respond to Australia’s key health priorities.

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Displaying 1 - 20 of 21 articles

Here’s what happens to your penis as you age

Rob McLachlan , Hudson Institute ; Jinghang Luo , Hudson Institute , and Tim Moss , Monash University

Problems conceiving are not just about women. Male infertility is behind 1 in 3 IVF cycles

Karin Hammarberg , Monash University ; Georgina Chambers , UNSW Sydney , and Rob McLachlan , Hudson Institute

1 in 10 women are affected by endometriosis. So why does it take so long to diagnose?

Caroline Gargett , Hudson Institute ; Caitlin Filby , Hudson Institute , and Fiona Cousins , Hudson Institute

Being South Asian is as great a risk factor for stillbirth as smoking

Miranda Davies-Tuck , Hudson Institute ; Euan Wallace , Hudson Institute , and Mary-Ann Davey , Monash University

La créatine qui fait les muscles plus forts, est-elle  utile ? Et sans danger ?

Hayley Dickinson , Hudson Institute and Stacey Ellery , Hudson Institute

Creatine: what is it and should we supplement our diets with it?

Why women’s eggs run out and what can be done about it

John (Jock) Kerr Findlay , Hudson Institute ; Karla Hutt , Monash University , and Kate Stern , The University of Melbourne

Gene editing in embryos is fraught with scientific and ethical issues

Patrick Western , Hudson Institute

Here’s what you need to know about testosterone

Rob McLachlan , Hudson Institute

‘Natural’ hormone therapy no panacea for menopause symptoms

Rhonda Garad , Deakin University and Henry Burger , Hudson Institute

Clue in ovarian cancer could mean potential treatment

Sasha Petrova, The Conversation

Nearly two thirds of men over 45 report erectile dysfunction: study

Zoe Ferguson, The Conversation

Glossary: ‘sports science’ drugs

Ian Musgrave , University of Adelaide ; Benjamin Koh , University of Technology Sydney , and Peter Fuller , Hudson Institute

Nutrient in red meat linked to heart disease

Fron Jackson-Webb , The Conversation

Preventing pregnancy and STIs: the quest for the ultra contraceptive

Lois Salamonsen , Hudson Institute

Male contraceptive pill a step closer

Charis Palmer, The Conversation

Contraception: best for women, babies and the planet

Lois Salamonsen , Hudson Institute and Gui-Ying Nie , Hudson Institute

Hormone replacement therapy and cancer? Let’s get the facts straight

Henry Burger , Hudson Institute

Monday’s medical myth: wearing tight undies will make you infertile

Monday’s medical myth: men also go through menopause

Carolyn Allan , Hudson Institute

Ovarian Cancer Research Foundation Fellow, Hudson Institute

Postdoctoral Scientist, Endometrial Stem Cell Biology, Hudson Institute

NHMRC Leadership Fellow and Head of Women's Health Theme, The Ritchie Centre, Hudson Institute of Medical Research, Hudson Institute

Chair professor, Hudson Institute

Postdoctoral Research Scientist, Endometrial Stem Cell Biology, Hudson Institute

Research Group Head, Embryology and Placental Biology, Hudson Institute

Emeritus Director, Hudson Institute

Andrology Fellow, Hudson Institute

Distinguished Scientist, Hudson Institute

Senior Fellow, Hudson Institute

Perinatal Epidemiologist and NHMRC Early Career Research Fellow, Hudson Institute

Research Group Head, Germ Cell Development and Epigenetics, Hudson Institute

Professor of Endocrinology, Hudson Institute

Professor and clinician in fertility medicine, Hudson Institute

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Hudson Institute of Medical Research

Principal Investigators

Clayton, Australia

Institution

A global bioscience medical research leader, Hudson Institute ’s sole focus is on powering breakthrough scientific discoveries into improved healthcare that will transform lives. Our 442 scientists research four areas of medical need - inflammation, cancer, reproductive health and pregnancy, and infant and child health .

The Hudson Monash Paediatric Precision Medicine (HMPPM) Program hopes to significantly improve treatment for childhood cancer patients with the greatest unmet clinical need – those diagnosed with brain cancers and solid tumours.

Clinical experience based on patient need informs Hudson Institute’s research enquiry, and our close ties with medical staff and industry support the translation of our discoveries into new preventative approaches, therapies and devices for patients.

Hudson Institute is located within a major scientific research and medical innovation hub in Melbourne’s south-eastern corridor. With our precinct partners, Monash Health and Monash University, we deliver outstanding healthcare, education and leading research.

Dilru Habarakada| Biospecimen Coordinator

Hudson Institute is a leading Australian medical research institute recognised internationally for discovery science and translational research. They are research leaders in four areas of medical need

Reproductive health and pregnancy  – addressing the challenges of infertility and complications during pregnancy, and progressing women’s health.

Infant and child health  – protecting vulnerable newborns from complications during birth, in the critical early weeks of life and exploring better treatments for childhood diseases.

Inflammation  – exploring how their body responds to infection and tissue damage with inflammation, and using this knowledge to fight infectious diseases, cancer and autoimmune diseases.

Cancer  – investigating the molecular and cellular mechanisms that lead to the development of cancer and how these insights may be used to better diagnose, detect and treat malignancies.

Their history – 75 years leading discovery

Two of Australia’s most trusted names in medical research, Prince Henry’s Institute of Medical Research and Monash Institute of Medical Research, merged in 2014 to form Hudson Institute of Medical Research. Combined, they have more than 75 years’ experience in research discoveries to Australia and beyond.

Their institute is named after Professor Bryan Hudson, the Founding Director of Prince Henry’s Institute and Founding Chair of the Department of Medicine at Monash University.

Type of organization

Company Offices

• 27-31 Wright Street

Isaac Woodhouse , Senior Bioinformatician

• Research Support Staff,  Translational Antigen Discovery
•     [email protected]

Isaac Woodhouse is a member of the Translational Antigen Discovery Research group in the Centre for Cancer Research.

Learn more about my group's research

Areas of interest

Childhood cancer

Research group

Translational Antigen Discovery

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