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In a randomized and controlled psychology experiment , the researchers are examining the impact of an experimental condition on a group of participants (does the independent variable 'X' cause a change in the dependent variable 'Y'?). To determine cause and effect, there must be at least two groups to compare, the experimental group and the control group.
The participants who are in the experimental condition are those who receive the treatment or intervention of interest. The data from their outcomes are collected and compared to the data from a group that did not receive the experimental treatment. The control group may have received no treatment at all, or they may have received a placebo treatment or the standard treatment in current practice.
Comparing the experimental group to the control group allows researchers to see how much of an impact the intervention had on the participants.
Imagine that you want to do an experiment to determine if listening to music while working out can lead to greater weight loss. After getting together a group of participants, you randomly assign them to one of three groups. One group listens to upbeat music while working out, one group listens to relaxing music, and the third group listens to no music at all. All of the participants work out for the same amount of time and the same number of days each week.
In this experiment, the group of participants listening to no music while working out is the control group. They serve as a baseline with which to compare the performance of the other two groups. The other two groups in the experiment are the experimental groups. They each receive some level of the independent variable, which in this case is listening to music while working out.
In this experiment, you find that the participants who listened to upbeat music experienced the greatest weight loss result, largely because those who listened to this type of music exercised with greater intensity than those in the other two groups. By comparing the results from your experimental groups with the results of the control group, you can more clearly see the impact of the independent variable.
When it comes to using experimental groups in a psychology experiment, there are a few important things to know:
Experiments play an important role in the research process and allow psychologists to investigate cause-and-effect relationships between different variables. Having one or more experimental groups allows researchers to vary different levels or types of the experimental variable and then compare the effects of these changes against a control group. The goal of this experimental manipulation is to gain a better understanding of the different factors that may have an impact on how people think, feel, and act.
Byrd-Bredbenner C, Wu F, Spaccarotella K, Quick V, Martin-Biggers J, Zhang Y. Systematic review of control groups in nutrition education intervention research . Int J Behav Nutr Phys Act. 2017;14(1):91. doi:10.1186/s12966-017-0546-3
Steingrimsdottir HS, Arntzen E. On the utility of within-participant research design when working with patients with neurocognitive disorders . Clin Interv Aging. 2015;10:1189-1200. doi:10.2147/CIA.S81868
Oberste M, Hartig P, Bloch W, et al. Control group paradigms in studies investigating acute effects of exercise on cognitive performance—An experiment on expectation-driven placebo effects . Front Hum Neurosci. 2017;11:600. doi:10.3389/fnhum.2017.00600
Kim H. Statistical notes for clinical researchers: Analysis of covariance (ANCOVA) . Restor Dent Endod . 2018;43(4):e43. doi:10.5395/rde.2018.43.e43
Bate S, Karp NA. A common control group — Optimising the experiment design to maximise sensitivity . PLoS ONE. 2014;9(12):e114872. doi:10.1371/journal.pone.0114872
Myers A, Hansen C. Experimental Psychology . 7th Ed. Cengage Learning; 2012.
By Kendra Cherry, MSEd Kendra Cherry, MS, is a psychosocial rehabilitation specialist, psychology educator, and author of the "Everything Psychology Book."
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Methodology
Published on April 19, 2021 by Pritha Bhandari . Revised on June 22, 2023.
In experiments , researchers manipulate independent variables to test their effects on dependent variables. In a controlled experiment , all variables other than the independent variable are controlled or held constant so they don’t influence the dependent variable.
Controlling variables can involve:
Why does control matter in experiments, methods of control, problems with controlled experiments, other interesting articles, frequently asked questions about controlled experiments.
Control in experiments is critical for internal validity , which allows you to establish a cause-and-effect relationship between variables. Strong validity also helps you avoid research biases , particularly ones related to issues with generalizability (like sampling bias and selection bias .)
Extraneous variables are factors that you’re not interested in studying, but that can still influence the dependent variable. For strong internal validity, you need to remove their effects from your experiment.
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You can control some variables by standardizing your data collection procedures. All participants should be tested in the same environment with identical materials. Only the independent variable (e.g., ad color) should be systematically changed between groups.
Other extraneous variables can be controlled through your sampling procedures . Ideally, you’ll select a sample that’s representative of your target population by using relevant inclusion and exclusion criteria (e.g., including participants from a specific income bracket, and not including participants with color blindness).
By measuring extraneous participant variables (e.g., age or gender) that may affect your experimental results, you can also include them in later analyses.
After gathering your participants, you’ll need to place them into groups to test different independent variable treatments. The types of groups and method of assigning participants to groups will help you implement control in your experiment.
Controlled experiments require control groups . Control groups allow you to test a comparable treatment, no treatment, or a fake treatment (e.g., a placebo to control for a placebo effect ), and compare the outcome with your experimental treatment.
You can assess whether it’s your treatment specifically that caused the outcomes, or whether time or any other treatment might have resulted in the same effects.
To test the effect of colors in advertising, each participant is placed in one of two groups:
To avoid systematic differences and selection bias between the participants in your control and treatment groups, you should use random assignment .
This helps ensure that any extraneous participant variables are evenly distributed, allowing for a valid comparison between groups .
Random assignment is a hallmark of a “true experiment”—it differentiates true experiments from quasi-experiments .
Masking in experiments means hiding condition assignment from participants or researchers—or, in a double-blind study , from both. It’s often used in clinical studies that test new treatments or drugs and is critical for avoiding several types of research bias .
Sometimes, researchers may unintentionally encourage participants to behave in ways that support their hypotheses , leading to observer bias . In other cases, cues in the study environment may signal the goal of the experiment to participants and influence their responses. These are called demand characteristics . If participants behave a particular way due to awareness of being observed (called a Hawthorne effect ), your results could be invalidated.
Using masking means that participants don’t know whether they’re in the control group or the experimental group. This helps you control biases from participants or researchers that could influence your study results.
You use an online survey form to present the advertisements to participants, and you leave the room while each participant completes the survey on the computer so that you can’t tell which condition each participant was in.
Although controlled experiments are the strongest way to test causal relationships, they also involve some challenges.
Especially in research with human participants, it’s impossible to hold all extraneous variables constant, because every individual has different experiences that may influence their perception, attitudes, or behaviors.
But measuring or restricting extraneous variables allows you to limit their influence or statistically control for them in your study.
Controlled experiments have disadvantages when it comes to external validity —the extent to which your results can be generalized to broad populations and settings.
The more controlled your experiment is, the less it resembles real world contexts. That makes it harder to apply your findings outside of a controlled setting.
There’s always a tradeoff between internal and external validity . It’s important to consider your research aims when deciding whether to prioritize control or generalizability in your experiment.
If you want to know more about statistics , methodology , or research bias , make sure to check out some of our other articles with explanations and examples.
Research bias
In a controlled experiment , all extraneous variables are held constant so that they can’t influence the results. Controlled experiments require:
Depending on your study topic, there are various other methods of controlling variables .
An experimental group, also known as a treatment group, receives the treatment whose effect researchers wish to study, whereas a control group does not. They should be identical in all other ways.
Experimental design means planning a set of procedures to investigate a relationship between variables . To design a controlled experiment, you need:
When designing the experiment, you decide:
Experimental design is essential to the internal and external validity of your experiment.
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What is a control group in an experiment.
A control group is a set of subjects in an experiment who are not exposed to the independent variable. The purpose of a control group is to serve as a baseline for comparison. By having a group that is not exposed to the treatment, researchers can compare the results of the experimental group and determine whether the independent variable had an impact.
In some cases, there may be more than one control group. This is often done when there are multiple treatments or when researchers want to compare different groups of subjects. Having multiple control groups allows researchers to isolate the effect of each treatment and better understand how each one works.
Control groups are an important part of any experiment, as they help ensure that the results are accurate and reliable. Without a control group, it would be difficult to determine whether the results of an experiment are due to the independent variable or other factors.
When designing an experiment, it is important to carefully consider what kind of control group you will need. There are many different ways to set up a control group, and the best approach will depend on the specific goals of your research.
A control group is a group in an experiment that does not receive the experimental treatment. The purpose of a control group is to provide a baseline against which to compare the experimental group results.
An experimental group is a group in an experiment that receives the experimental treatment. The purpose of an experimental group is to test whether or not the experimental treatment has an effect.
The differences between control and experimental groups are important to consider when designing an experiment. The most important difference is that the control group provides a comparison for the results of the experimental group. This comparison is essential in order to determine whether or not the experimental treatment had an effect. Without a control group, it would be impossible to know if the results of the experiment are due to the treatment or not.
Another important difference between a control group and an experimental group is that the experimental group is the only group that receives the experimental treatment. This is necessary in order to ensure that any results seen in the experimental group can be attributed to the treatment and not to other factors.
Control groups and experimental groups are both essential parts of experiments. Without a control group, it would be impossible to know if the results of an experiment are due to the treatment or not. Without an experimental group, it would be impossible to test whether or not a treatment has an effect.
The purpose of a control group is to serve as a baseline for comparison. By having a group that is not exposed to the treatment, researchers can compare the results of the experimental group and determine whether the independent variable had an impact.
A control group is an essential part of any experiment. It is a group of subjects who are not exposed to the independent variable being tested. The purpose of a control group is to provide a baseline against which the results from the treatment group can be compared.
Without a control group, it would be impossible to determine whether the results of an experiment are due to the treatment or some other factor. For example, imagine you are testing the effects of a new drug on patients with high blood pressure. If you did not have a control group, you would not know if the decrease in blood pressure was due to the drug or something else, such as the placebo effect.
A control group must be carefully designed to match the treatment group in all important respects, except for the one factor that is being tested. This ensures that any differences in the results can be attributed to the independent variable and not to other factors.
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How science REALLY works...
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The “scientific method” is traditionally presented in the first chapter of science textbooks as a simple, linear, five- or six-step procedure for performing scientific investigations. Although the Scientific Method captures the core logic of science (testing ideas with evidence), it misrepresents many other aspects of the true process of science — the dynamic, nonlinear, and creative ways in which science is actually done. In fact, the Scientific Method more accurately describes how science is summarized after the fact — in textbooks and journal articles — than how scientific research is actually performed. Teachers may ask that students use the format of the scientific method to write up the results of their investigations (e.g., by reporting their question, background information, hypothesis, study design, data analysis, and conclusion ), even though the process that students went through in their investigations may have involved many iterations of questioning, background research, data collection, and data analysis and even though the students’ “conclusions” will always be tentative ones. To learn more about how science really works and to see a more accurate representation of this process, visit The real process of science .
Scientists often seem tentative about their explanations because they are aware that those explanations could change if new evidence or perspectives come to light. When scientists write about their ideas in journal articles, they are expected to carefully analyze the evidence for and against their ideas and to be explicit about alternative explanations for what they are observing. Because they are trained to do this for their scientific writing, scientist often do the same thing when talking to the press or a broader audience about their ideas. Unfortunately, this means that they are sometimes misinterpreted as being wishy-washy or unsure of their ideas. Even worse, ideas supported by masses of evidence are sometimes discounted by the public or the press because scientists talk about those ideas in tentative terms. It’s important for the public to recognize that, while provisionality is a fundamental characteristic of scientific knowledge, scientific ideas supported by evidence are trustworthy. To learn more about provisionality in science, visit our page describing how science builds knowledge . To learn more about how this provisionality can be misinterpreted, visit a section of the Science toolkit .
Peer review helps assure the quality of published scientific work: that the authors haven’t ignored key ideas or lines of evidence, that the study was fairly-designed, that the authors were objective in their assessment of their results, etc. This means that even if you are unfamiliar with the research presented in a particular peer-reviewed study, you can trust it to meet certain standards of scientific quality. This also saves scientists time in keeping up-to-date with advances in their fields by weeding out untrustworthy studies. Peer-reviewed work isn’t necessarily correct or conclusive, but it does meet the standards of science. To learn more, visit Scrutinizing science .
In an experiment, the independent variables are the factors that the experimenter manipulates. The dependent variable is the outcome of interest—the outcome that depends on the experimental set-up. Experiments are set-up to learn more about how the independent variable does or does not affect the dependent variable. So, for example, if you were testing a new drug to treat Alzheimer’s disease, the independent variable might be whether or not the patient received the new drug, and the dependent variable might be how well participants perform on memory tests. On the other hand, to study how the temperature, volume, and pressure of a gas are related, you might set up an experiment in which you change the volume of a gas, while keeping the temperature constant, and see how this affects the gas’s pressure. In this case, the independent variable is the gas’s volume, and the dependent variable is the pressure of the gas. The temperature of the gas is a controlled variable. To learn more about experimental design, visit Fair tests: A do-it-yourself guide .
In scientific testing, a control group is a group of individuals or cases that is treated in the same way as the experimental group, but that is not exposed to the experimental treatment or factor. Results from the experimental group and control group can be compared. If the control group is treated very similarly to the experimental group, it increases our confidence that any difference in outcome is caused by the presence of the experimental treatment in the experimental group. For an example, visit our side trip Fair tests in the field of medicine .
A negative control group is a control group that is not exposed to the experimental treatment or to any other treatment that is expected to have an effect. A positive control group is a control group that is not exposed to the experimental treatment but that is exposed to some other treatment that is known to produce the expected effect. These sorts of controls are particularly useful for validating the experimental procedure. For example, imagine that you wanted to know if some lettuce carried bacteria. You set up an experiment in which you wipe lettuce leaves with a swab, wipe the swab on a bacterial growth plate, incubate the plate, and see what grows on the plate. As a negative control, you might just wipe a sterile swab on the growth plate. You would not expect to see any bacterial growth on this plate, and if you do, it is an indication that your swabs, plates, or incubator are contaminated with bacteria that could interfere with the results of the experiment. As a positive control, you might swab an existing colony of bacteria and wipe it on the growth plate. In this case, you would expect to see bacterial growth on the plate, and if you do not, it is an indication that something in your experimental set-up is preventing the growth of bacteria. Perhaps the growth plates contain an antibiotic or the incubator is set to too high a temperature. If either the positive or negative control does not produce the expected result, it indicates that the investigator should reconsider his or her experimental procedure. To learn more about experimental design, visit Fair tests: A do-it-yourself guide .
In a correlational study, a scientist looks for associations between variables (e.g., are people who eat lots of vegetables less likely to suffer heart attacks than others?) without manipulating any variables (e.g., without asking a group of people to eat more or fewer vegetables than they usually would). In a correlational study, researchers may be interested in any sort of statistical association — a positive relationship among variables, a negative relationship among variables, or a more complex one. Correlational studies are used in many fields (e.g., ecology, epidemiology, astronomy, etc.), but the term is frequently associated with psychology. Correlational studies are often discussed in contrast to experimental studies. In experimental studies, researchers do manipulate a variable (e.g., by asking one group of people to eat more vegetables and asking a second group of people to eat as they usually do) and investigate the effect of that change. If an experimental study is well-designed, it can tell a researcher more about the cause of an association than a correlational study of the same system can. Despite this difference, correlational studies still generate important lines of evidence for testing ideas and often serve as the inspiration for new hypotheses. Both types of study are very important in science and rely on the same logic to relate evidence to ideas. To learn more about the basic logic of scientific arguments, visit The core of science .
Deductive reasoning involves logically extrapolating from a set of premises or hypotheses. You can think of this as logical “if-then” reasoning. For example, IF an asteroid strikes Earth, and IF iridium is more prevalent in asteroids than in Earth’s crust, and IF nothing else happens to the asteroid iridium afterwards, THEN there will be a spike in iridium levels at Earth’s surface. The THEN statement is the logical consequence of the IF statements. Another case of deductive reasoning involves reasoning from a general premise or hypothesis to a specific instance. For example, based on the idea that all living things are built from cells, we might deduce that a jellyfish (a specific example of a living thing) has cells. Inductive reasoning, on the other hand, involves making a generalization based on many individual observations. For example, a scientist who samples rock layers from the Cretaceous-Tertiary (KT) boundary in many different places all over the world and always observes a spike in iridium may induce that all KT boundary layers display an iridium spike. The logical leap from many individual observations to one all-inclusive statement isn’t always warranted. For example, it’s possible that, somewhere in the world, there is a KT boundary layer without the iridium spike. Nevertheless, many individual observations often make a strong case for a more general pattern. Deductive, inductive, and other modes of reasoning are all useful in science. It’s more important to understand the logic behind these different ways of reasoning than to worry about what they are called.
Scientific theories are broad explanations for a wide range of phenomena, whereas hypotheses are proposed explanations for a fairly narrow set of phenomena. The difference between the two is largely one of breadth. Theories have broader explanatory power than hypotheses do and often integrate and generalize many hypotheses. To be accepted by the scientific community, both theories and hypotheses must be supported by many different lines of evidence. However, both theories and hypotheses may be modified or overturned if warranted by new evidence and perspectives.
A null hypothesis is usually a statement asserting that there is no difference or no association between variables. The null hypothesis is a tool that makes it possible to use certain statistical tests to figure out if another hypothesis of interest is likely to be accurate or not. For example, if you were testing the idea that sugar makes kids hyperactive, your null hypothesis might be that there is no difference in the amount of time that kids previously given a sugary drink and kids previously given a sugar-substitute drink are able to sit still. After making your observations, you would then perform a statistical test to determine whether or not there is a significant difference between the two groups of kids in time spent sitting still.
Ockham’s razor is an idea with a long philosophical history. Today, the term is frequently used to refer to the principle of parsimony — that, when two explanations fit the observations equally well, a simpler explanation should be preferred over a more convoluted and complex explanation. Stated another way, Ockham’s razor suggests that, all else being equal, a straightforward explanation should be preferred over an explanation requiring more assumptions and sub-hypotheses. Visit Competing ideas: Other considerations to read more about parsimony.
Rigorous and well controlled scientific investigations 1 have examined these topics and have found no evidence supporting their usual interpretations as natural phenomena (i.e., ghosts as apparitions of the dead, ESP as the ability to read minds, and astrology as the influence of celestial bodies on human personalities and affairs) — although, of course, different people interpret these topics in different ways. Science can investigate such phenomena and explanations only if they are thought to be part of the natural world. To learn more about the differences between science and astrology, visit Astrology: Is it scientific? To learn more about the natural world and the sorts of questions and phenomena that science can investigate, visit What’s natural ? To learn more about how science approaches the topic of ESP, visit ESP: What can science say?
Knowledge generated by science has had many effects that most would classify as positive (e.g., allowing humans to treat disease or communicate instantly with people half way around the world); it also has had some effects that are often considered negative (e.g., allowing humans to build nuclear weapons or pollute the environment with industrial processes). However, it’s important to remember that the process of science and scientific knowledge are distinct from the uses to which people put that knowledge. For example, through the process of science, we have learned a lot about deadly pathogens. That knowledge might be used to develop new medications for protecting people from those pathogens (which most would consider a positive outcome), or it might be used to build biological weapons (which many would consider a negative outcome). And sometimes, the same application of scientific knowledge can have effects that would be considered both positive and negative. For example, research in the first half of the 20th century allowed chemists to create pesticides and synthetic fertilizers. Supporters argue that the spread of these technologies prevented widespread famine. However, others argue that these technologies did more harm than good to global food security. Scientific knowledge itself is neither good nor bad; however, people can choose to use that knowledge in ways that have either positive or negative effects. Furthermore, different people may make different judgments about whether the overall impact of a particular piece of scientific knowledge is positive or negative. To learn more about the applications of scientific knowledge, visit What has science done for you lately?
1 For examples, see:
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Where randomized experiments aren’t possible, researchers have a new statistical tool, based on the research of kathleen li.
Whether they’re studying vaccine adoption rates or consumer preferences, randomized experiments are the gold standard in the world of research.
In such experiments, researchers split study participants into groups by chance. One group undergoes an intervention. The other — the control group — does not. Then, researchers can say with confidence whether a certain intervention made an impact.
In the real world, though, randomized experiments are not always possible, says Texas McCombs Assistant Professor of Marketing Kathleen Li. “In many situations, you simply can’t, because you can’t convince companies to do it, or maybe it’s against the law. It’s still important, however, to know an intervention’s effect.”
In new research, with Venkatesh Shankar of Texas A&M University, Li creates a statistical tool for such situations. Called two-step synthetic control, it can help researchers get meaningful results when randomized trials are not feasible.
“Our framework allows managers and policymakers to estimate effects they previously weren’t able to estimate accurately,” Li says. “They get a more precise estimate that can help them make more informed decisions.”
A More Flexible Approach
Li’s tool adapts an existing research workaround, known as the synthetic control method. As the name implies, it creates synthetic control groups from the data, in place of real ones. The groups are weighted statistically and compared with a group undergoing an intervention.
But the synthetic control method doesn’t perfectly apply to all situations, especially ones in which the intervention group is very different from its control groups. In these scenarios, the method could lead to less accurate results.
One problem, says Li, is that the method is somewhat inflexible. The control groups that make up its weighted combination must add up to 100%. For example, researchers could decide that one group accounts for 20% and another 80%.
A more flexible method might lead to more accurate results, the researchers say, and they’ve devised one. Their two-step synthetic control approach goes through two stages:
· First, it determines whether the traditional synthetic control method applies to a given case.
· If it does not, the second step uses a more flexible framework that allows weighted controls to differ from 100% or to shift the control group up and down.
“This approach balances the tradeoff,” Li says. “We first want to get an accurate effect, but at the same time, we also want to be as precise as possible in order to provide the most informative information to key decision makers.”
Accuracy, she adds, is about how close a measurement is to the true value. Precision, on the other hand, refers to the tightness of the numerical band the measurement is thought to fall in.
Measuring Tampon Sales
To test their new method on a real-world situation, Li and Shankar looked at sales of tampons: how they responded in 2016, when New York repealed a sales tax on them.
Sales taxes on tampons have been a contentious issue worldwide, and many countries — including Australia, Germany, and India — have abolished or reduced them. Proponents of repeal argue that feminine hygiene products are basic necessities and should not be taxed.
But by 2019, only 13 states in the U.S. had repealed the tax, with opponents arguing that repeal would decrease state revenues. One key point of contention for policymakers has been how repeal would affect tampon sales.
To find out, Li and Shankar gathered 52 weeks of sales data before New York’s repeal and 17 weeks after. Their control group was 35 states that did not repeal the tax.
In their first step, the researchers applied the traditional synthetic control method to the data. They found the traditional method probably overestimated the actual increase in weekly sales, showing a 2.5% rise in New York.
In the second step, the researchers applied a more flexible method. It estimated that New York’s repeal caused a more modest increase in weekly tampon sales, of only 2.08%. That estimate probably is more accurate, as the more flexible method matches the actual sales figures before the intervention better.
Any market or public policy researcher can use the new method, Li says. In fact, she and Shankar will be making it available online for all to use.
But she offers one caution: More flexible methods tend to be less precise, with wider bands of uncertainty.
“That’s the trade-off,” Li says. “You want to be able to use the method that’s just as flexible as you need it. It’s why having this tool to see how flexible you can go and still be precise is critical.”
“A Two-Step Synthetic Control Approach for Estimating Causal Effects of Marketing Events” is forthcoming, online in Management Science.
Story by Deborah Lynn Blumberg
BMC Medical Education volume 24 , Article number: 860 ( 2024 ) Cite this article
Metrics details
This study aimed to assess the effectiveness of the BOPPPS model (bridge-in, learning objective, pre-test, participatory learning, post-test, and summary) in otolaryngology education for five-year undergraduate students.
A non-randomized controlled trial was conducted with 167 five-year undergraduate students from Anhui Medical University, who were allocated to an experimental group and a control group. The experimental group received instruction using the BOPPPS model, while the control group underwent traditional teaching methods. The evaluation of the teaching effectiveness was performed through an anonymous questionnaire based on the course evaluation questionnaire. Students’ perspectives and self-evaluations were quantified using a five-point Likert scale. Furthermore, students’ comprehension of the course content was measured through a comprehensive final examination at the end of the semester.
Students in the experimental group reported significantly higher scores in various competencies compared to the control group: planning work (4.27 ± 0.676 vs. 4.03 ± 0.581, P < 0.05), problem-solving skills (4.31 ± 0.624 vs. 4.03 ± 0.559, P < 0.01), teamwork abilities (4.19 ± 0.704 vs. 3.87 ± 0.758, P < 0.05), and analytical skills (4.31 ± 0.719 vs. 4.05 ± 0.622, P < 0.05). They also reported higher motivation for learning (4.48 ± 0.618 vs. 4.09 ± 0.582, P < 0.01). Additionally, students in the experimental group felt more confident tackling unfamiliar problems (4.21 ± 0.743 vs. 3.95 ± 0.636, P < 0.05), had a clearer understanding of teachers’ expectations (4.31 ± 0.552 vs. 4.08 ± 0.555, P < 0.05), and perceived more effort from teachers to understand their difficulties (4.42 ± 0.577 vs. 4.13 ± 0.59, P < 0.01). They emphasized comprehension over memorization (3.65 ± 1.176 vs. 3.18 ± 1.065, P < 0.05) and received more helpful feedback (4.40 ± 0.574 vs. 4.08 ± 0.585, P < 0.01). Lecturers were rated better at explaining concepts (4.42 ± 0.539 vs. 4.08 ± 0.619, P < 0.01) and making subjects interesting (4.50 ± 0.546 vs. 4.08 ± 0.632, P < 0.01). Overall, the experimental group expressed higher course satisfaction (4.56 ± 0.542 vs. 4.34 ± 0.641, P < 0.05). In terms of examination performance, the experimental group scored higher on the final examination (87.7 ± 6.7 vs. 84.0 ± 7.7, P < 0.01) and in noun-interpretation (27.0 ± 1.6 vs. 26.1 ± 2.4, P < 0.01).
The BOPPPS model emerged as an effective and innovative teaching method, particularly in enhancing students’ competencies in otolaryngology education. Based on the findings of this study, educators and institutions were encouraged to consider incorporating the BOPPPS model into their curricula to enhance the learning experiences and outcomes of students.
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Otolaryngology is a distinctive clinical discipline characterized by its unique professional attributes that focus on the diagnosis and treatment of disorders affecting the ears, nose, throat, head and neck regions. Otolaryngologists frequently encounter various clinical manifestations associated with systemic diseases, requiring advanced clinical reasoning and complex problem-solving abilities [ 1 ]. Undergraduate otolaryngology education encompasses a wide range of knowledge areas and emphasizes the integration of theory and practice to train a highly qualified cadre of doctors [ 2 ]. The challenge of this specialized education lies in providing effective teaching modalities that ensure competency in the diagnosis and management of otolaryngologic disorders within a standardized framework [ 2 , 3 , 4 ].
In medical curricula, the traditional teaching prevalent in the current evidence relies on lecture-based instruction and emphasizes the delivery of syllabi and concepts [ 4 ]. However, the term “traditional” is not clearly defined and may vary depending on the individual teacher. In this format, students first receive reading materials, including textbooks and the course syllabus, and then passively absorb knowledge through face-to-face classroom sessions, while teachers impart theoretical knowledge, answer questions, and repeat any knowledge points that students had not been fully understood in the class, via PowerPoint slides and handouts [ 5 , 6 ]. This model often results in unsatisfactory learning outcomes as medical students acquire knowledge passively from instructors with little interaction, resulting in decreased motivation to study and innovate. Moreover, otolaryngology experience and training in medical schools have been gradually declining at undergraduate medical education worldwide [ 7 , 8 ]. As a consequence, undergraduate students and primary care practitioners often exhibit low competency in managing ear, nose, and throat problems, such as difficulty in accurately diagnosing common conditions, limited proficiency in performing basic examinations, and insufficient knowledge of appropriate treatment protocols [ 4 , 9 , 10 , 11 , 12 ]. Thus, it is crucial to restructure the current educational approach from conventional didactic learning, aiming to enhance students’ competencies by incorporating focused teaching and skills training [ 3 ].
The BOPPPS (bridge-in, learning objective, pre-test, participatory learning, post-test, and summary) model was a six-stage framework which was originally developed by the Center for Teaching and Academic Development, University of British Columbia, Canada [ 13 ]. It offered a comprehensive and coherent teaching process and theoretical foundation to achieve learning objectives [ 5 ]. Moreover, it clearly organized the teaching process and creates a closed-loop teaching unit with an integrated system that emphasizes the effectiveness of learning outcomes and the diversity of teaching methods [ 5 ]. Several studies have demonstrated that the BOPPPS model is more effective than traditional instruction in enhancing students’ skills and knowledge, as well as improving their self-learning ability, academic performance, and learning satisfaction across various disciplines, such as ophthalmology, thoracic surgery and gynecology [ 5 , 14 , 15 , 16 , 17 , 18 ]. However, the application of the BOPPPS model in otolaryngology education has not been fully explored.
In fact, we first applied the single BOPPPS teaching to integration cases in the spring of 2021 for the students of Class 2017, and then in 2022 for Class 2018. Unlike traditional teaching, the BOPPPS model encouraged active engagement from students through participatory learning activities, fostering deeper understanding, critical thinking, and application of knowledge. Moreover, while traditional teaching may focus primarily on content delivery, the BOPPPS model emphasized the integration of theoretical concepts with practical clinical scenarios, thereby promoting a more holistic approach to learning [ 6 , 18 ]. In this study, we conducted a preliminary evaluation of the effectiveness of the BOPPPS model for otolaryngology education among five-year undergraduates.
This study was a non-randomized controlled trial conducted at Anhui Medical University between April 1, 2023, and May 30, 2023. We recruited 167 students majoring in clinical medicine from Anhui Medical University who were undergraduate students studying otolaryngology in their eighth semester. Informed consent was obtained from each participant prior to enrolment in the study. Each participant voluntarily agreed to take part in this study. The students were from almost all regions of China and approximately half of them were residents of Anhui province. They all received systematic pre-college education under the same guideline and using the same textbooks after passing the requirements of the entrance examination. The students were divided into 4 sections to be taught separately. Each section was usually taught by one teacher throughout the entire Otolaryngology course. All teachers had at least 10 years’ experience of teaching and met the standard requirements of teaching after group rehearsal of the course contents. We assigned them to two groups: an experimental group that used the BOPPPS model and a control group that used the traditional instructional approach.
The study conducted over two months, focusing on the effectiveness of the BOPPPS model in teaching otolaryngology. The experimental group applied the BOPPPS model, while the control group received traditional lecture-based instruction. Both groups covered a total of 49 topics related to otolaryngology, with chronic sinusitis being one example. The course comprised 27 sessions with 45 min per session. The study included 169 five-year undergraduate students from Anhui Medical University, with 49 students in the experimental group and 118 students in the control group. Students were allocated to these groups based on their class schedules and availability. The same curriculum was used as the teaching content for both groups of students. The teaching processes were completed within the same duration for the experimental group and the control group. The control group received mainly traditional teaching [ 19 ]. In the traditional lecture-based format, teachers delivered theoretical knowledge through PowerPoint slides, handouts, and lectures. Students passively received information and took notes. The traditional teaching sessions involved the following steps: Reading Material : Students first received the reading material, including textbooks and the course syllabus. Classroom Instruction : Teachers used overhead projectors and PowerPoint slides to deliver the content face-to-face, with minimal student interaction. Teaching Materials : Students had access to teaching materials and reference book. Question and Answer : Teachers answered students’ questions and repeated any points that were not fully understood.
The experimental group applied the BOPPPS model for teaching, using the topic on chronic sinusitis as an example. The BOPPPS model is composed of six parts [ 6 , 20 ]: Bridge-in : Before class, the teacher introduces two problems of chronic sinusitis from online searching platforms ( https://pubmed.ncbi.nlm.nih.gov ) to motivate students’ interest in learning clinical diseases characterized by “rhinorrhea” and “headache”. The teacher also provides a clinical case with a framework for understanding the course’s main content by asking students to recall the anatomy and physiology of the paranasal sinuses and the common symptoms of chronic sinusitis. Objective : According to the course syllabus of Anhui Medical University, the teacher clearly states the diagnosis and treatment of chronic sinusitis as the focus of the course. Pre-assessment : The teacher administers a quiz or a poll to assess the students’ prior knowledge and understanding of chronic sinusitis. The teacher also asks students to share their questions or difficulties about the topic. Participatory learning : The teacher divides the students into small groups and assigns each group a clinical case related to chronic sinusitis. The students are instructed to discuss the case in their groups and answer questions based on the pre-assessment such as: what are the possible causes and risk factors of chronic sinusitis? what are the diagnostic tests and criteria for chronic sinusitis? what are the treatment options and goals for chronic sinusitis? how would you educate the patient about prevention and self-care? The teacher facilitates the discussion by providing feedback, guidance and additional information as needed. Post-assessment : The teacher conducts another quiz or a poll to evaluate the students’ learning outcomes and progress after the participatory learning. The teacher also urges students to reflect on their learning experience and identify their strengths and weaknesses. The teacher adjusts the subsequent content to improve teaching efficiency based on the post-assessment. Summary : The teacher summarizes the main points and key concepts of chronic sinusitis. The teacher also reviews the learning objectives and emphasizes the clinical implications and applications of chronic sinusitis. The teacher encourages students to expand their learning beyond the course and seek further learning resources if interested, such as by consulting expert consensus and clinical guidelines (e.g., European Position Paper on Rhinosinusitis and Nasal Polyps, 2020). To ensure clarity and concision, the teaching flowchart is depicted in Fig. 1 .
Flowchart of BOPPPS and traditional instructional teaching using chronic sinusitis as an example. Bridge-in : following the problem introduction or a clinical case, delve into the interest motivation by exploring the symptoms of chronic sinusitis, such as “rhinorrhea” and “headache,” commonly searched online, sparking our curiosity about this condition. Objective : diagnosis and treatment of chronic sinusitis based on the course syllabus. Pre-assessment : a quiz/poll; sharing any questions or areas of difficulty regarding the topic. Participatory learning : students are divided into small groups to analyze clinical cases of chronic sinusitis, discussing causes, diagnostics, treatments, and patient education. Post-assessment : quiz/poll, student reflection on learning experience, and subsequent content adjustment for improved teaching efficiency. Summary : the teacher summarizes key points of chronic sinusitis, reviews learning objectives, underscores clinical implications, and encourages students to explore additional resources for further learning
To evaluate the efficacy of the BOPPPS instructional model, we administered an anonymous questionnaire to the students. The questionnaire was adapted from the course evaluation questionnaire [ 21 ]. The students from both groups filled out the questionnaire after completing the course. We quantified the students’ perspectives and self-evaluations using a five-point Likert-type scale ranging from a score of one for strong disagreement to a score of five for strong agreement.
We also tested the students’ understanding of the course content by administering a comprehensive final examination at the end of the semester. The written examination (with a total score of 100 points) assessed the theoretical knowledge of Otolaryngology. The examination questions consisted of three parts: medical-terms interpretation (28 points), single-choice questions (42 points) and short-answer questions (30 points). They were randomly selected from the examination question bank, which encompassed the students’ skills in Otolaryngology.
Statistical analyses were conducted using SPSS 26.0 (SPSS, Inc., Chicago, IL). The quantitative data were presented as means ± standard deviations and subjected to analysis using the t-test. Meanwhile, categorical data were analysed by the chi-square test. P < 0.05 indicated that the difference was statistically significant.
Table 1 depicted the main demographic features of the two groups of undergraduate students. The experimental group consisted of 49 students (30 males, 19 females) with a mean age of 21.29 years. The control group comprised 118 students (87 males, 31 female) with a mean age of 21.70 years. The two groups were comparable in their general characteristics, such as sex, age, and origin of the students ( P > 0.05). No significant differences were observed between the two groups regarding sex, age, and family background ( P > 0.05).
In Table 2 , we compared students’ perspectives in the control group to those of the experimental group. Students in both groups considered the otolaryngology course to be too heavy (3.56 ± 1.050 vs. 3.39 ± 0.894), overly theoretical and abstract (3.75 ± 1.139 vs. 3.36 ± 1.00) and needed a good memory (4.25 ± 0.700 vs. 4.13 ± 0.461). There was no significant difference in learning pressure (3.40 ± 1.125 vs. 3.20 ± 0.962, P > 0.05), course comprehension (3.42 ± 1.164 vs. 3.30 ± 1.013, P > 0.05), and time spent (3.73 ± 1.086 vs. 3.53 ± 0.910, P > 0.05) between the two groups. More students in the experimental group agreed that BOPPPS model significantly enhanced their ability to plan their own work (4.27 ± 0.676 vs. 4.03 ± 0.581, P < 0.05), developed their problem-solving skills (4.31 ± 0.624 vs. 4.03 ± 0.559, P < 0.01), helped them work as a team member (4.19 ± 0.704 vs.3.87 ± 0.758, P < 0.05), sharpen their analytical skills (4.31 ± 0.719 vs. 4.05 ± 0.622, P < 0.05), and improved their motivation for learning (4.48 ± 0.618 vs. 4.09 ± 0.582, P < 0.01) than the control group. Through the experimental group course, students felt more confident about tackling unfamiliar problems than through the control group course (4.21 ± 0.743 vs. 3.95 ± 0.636, P < 0.05). Compared to those in the control group, students in the experimental group demonstrated a significantly clearer understanding of the teaching staff’s expectations from the start (4.31 ± 0.552 vs. 4.08 ± 0.555, P < 0.05). Furthermore, the experimental group perceived a greater effort from the staff to understand their difficulties (4.42 ± 0.577 vs. 4.13 ± 0.59, P < 0.01), a stronger emphasis on comprehension rather than memorization (3.65 ± 1.176 vs. 3.18 ± 1.065, P < 0.05), and received more helpful feedback from the teaching staff (4.40 ± 0.574 vs.4.08 ± 0.585, P < 0.01). Additionally, students in the experimental group found the lecturers to be significantly better at explaining concepts (4.42 ± 0.539 vs.4.08 ± 0.619, P < 0.01) and perceived a higher level of effort in making the subjects interesting (4.50 ± 0.546 vs. 4.08 ± 0.632, P < 0.01) than those in the control group. Overall, the experimental group was significantly more satisfied with the course than the control group (4.56 ± 0.542 vs. 4.34 ± 0.641, P < 0.05).
The experimental group achieved significantly higher final examination scores compared to the control group (87.7 ± 6.7 vs. 84.0 ± 7.7), and the difference was statistically significant ( P = 0.004). The experimental group also obtained significantly higher scores in noun-interpretation than the control group (27.0 ± 1.6 vs. 26.1 ± 2.4, P = 0.005). However, there was no statistically significant difference in single-choice scores between the two groups (31.8 ± 6.1 vs. 30.0 ± 4.9, P = 0.076), as well as in short-answer scores (28.2 ± 3.3 vs. 28.0 ± 3.4, P = 0.690) (Fig. 2 ).
Comparison of examination scores between experimental and control groups
The evolution of medical education has been driven by advancements in medical knowledge and pedagogy, as well as the need to address the complexities of chronic disease management and adapt to demographic, economic, and organizational changes in the healthcare system [ 22 , 23 ]. In the past few decades, medical education has shifted from a disease-oriented approach to a problem-based approach, and finally to a competency-based approach [ 24 , 25 ]. This transformation signified a crucial shift towards a more holistic and integrated model of otolaryngologic medical education [ 26 , 27 , 28 ]. It recognized the dynamic and complex nature of the field and the changing healthcare environment, where the demands on future otolaryngologists extended far beyond mere anatomical knowledge.
This study was the first application of the BOPPPS model in otolaryngologic education for the fourth year undergraduates in terms of students’ perspectives and examination scores. The findings revealed several positive outcomes. Firstly, the BOPPPS model significantly developed students’ problem-solving skills, improved teamwork, sharpened analytical skills, and increased students’ motivation for learning by engaging students in challenging clinical scenarios and encouraging them to analyse complex situations. Those skills are crucial and essential to make quick and accurate decisions for optimal patient treatment. Several studies demonstrated that the BOPPPS model enhanced clinical practice abilities and increased student satisfaction, and that it better inspired enthusiasm and enhanced comprehensive abilities in clinical teaching practice, which was consistent with our findings [ 6 , 18 ]. Secondly, the model promoted effective communication and cooperation by engaging students in participatory activities and group discussions. This approach enhanced critical thinking abilities during problem-solving exercises, enabling students to assess medical information, interpret diagnostic findings, and explore diverse treatment alternatives. Thirdly, it cultivated a supportive and engaging learning environment, leading to increased confidence and a deeper understanding of the subject matter for students. By prioritizing comprehension over memorization and providing personalized guidance, the model optimized students’ learning strategies. These results were confirmed by a recent meta-analysis, which highlights the significant impact of the BOPPPS model across multiple disciplines in Chinese medical education [ 5 ]. The most crucial outcome was the significantly higher final examination scores achieved by the experimental group. These scores were not only important for evaluating the students’ academic achievement, but also for measuring educational quality in the field [ 6 , 18 ]. The application of the BOPPPS model with or without innovative teaching in medical education demonstrated its effectiveness, fulfilling the requirements of competency-based teaching, equipping future otolaryngologists with the necessary skills to make quick and accurate decisions in patient treatment, and meeting the needs of modern medical education [ 14 , 16 , 29 , 30 ].
Competency-based education was an outcomes-centered approach that focused on mastering specific skills and knowledge required in a field of study, rather than memorizing facts and information [ 31 , 32 , 33 ]. In our study, the BOPPPS model, a six-stage framework, was used to design and deliver effective and engaging instruction for otolaryngology education. Our results demonstrated significant improvements in analytical skills, problem-solving abilities, and motivation, thereby supporting the effectiveness of the BOPPPS model in achieving competency-based educational outcomes. Each stage has a specific purpose and function in the teaching process [ 20 , 34 ].
Bridge-in: This stage aims to capture the students’ attention and interest by linking their prior knowledge and experience to the new topic or concept. This stage can help students activate their existing competencies and connect them to the new learning objectives, as well as motivate them to learn more.
Objective: This stage defines the clear and measurable learning outcomes that the students are expected to achieve by the end of the lesson. This stage can help students concentrate on mastering specific competencies required in their field of study, as well as provide them with clear criteria and expectations for assessment.
Pre-assessment: This stage evaluates the students’ current level of knowledge and skills related to the topic, as well as their learning needs and preferences. This stage can help teachers identify the students’ strengths and weaknesses, as well as tailor their instruction accordingly. This stage can also help students self-assess their competencies and set their own learning goals.
Participatory learning: This stage engages the students in active and collaborative learning activities that help them acquire and apply the new knowledge and skills. This stage can help students develop and enhance their competencies through problem-solving exercises, case studies, simulations, role-plays, and other interactive methods. This stage can also help students practice their critical thinking, communication, teamwork, and other soft skills that are essential for their field of study.
Post-assessment: This stage evaluates the students’ learning outcomes and progress by measuring their achievement of the learning objectives. This stage can help teachers provide feedback and guidance to the students on their performance and improvement. This stage can also help students demonstrate their competencies and reflect on their learning process.
Summary: This stage reviews and reinforces the main points and key concepts of the lesson, as well as provides feedback and guidance for further learning. This stage can help students consolidate their competencies and transfer them to other contexts, as well as identify their areas for further development.
As a result, the BOPPPS model could provide a structured and systematic way to assess and enhance students’ competencies, as well as encourage active participation and collaboration among students [ 6 , 18 , 35 ]. By using the BOPPPS model, teachers could create a meaningful and memorable learning experience for their students, preparing them for real-world challenges in their field of study. By focusing on practical application, personalized feedback, and collaborative learning, the model fostered a transformative learning experience that empowered students to become competent and well-rounded professionals in their chosen field [ 5 , 17 ]. The model’s application provided a comprehensive and in-depth approach to develop students’ abilities, ensuring they were well-prepared for their future careers.
The results of this study suggested that educators and institutions should explore integrating the BOPPPS model into their curricula to optimize the learning experience for aspiring otolaryngologists. The findings also supported the wider adoption of competency-based pedagogy, emphasizing the potential of BOPPPS to enhance students’ perceptions, academic performance, and overall learning experiences in otolaryngology education and beyond, aligning with other studies [ 5 , 17 , 28 , 35 ]. The findings underscored the significance of learner-centered and practice-oriented approaches in medical education, providing useful insights for curriculum design and instructional strategies [ 35 ]. As educators and institutions seeked to optimize learning outcomes and prepared competent healthcare professionals, the BOPPPS model served as a promising and effective tool for shaping the future of otolaryngology medical education [ 6 , 18 ].
All students from the five-year undergraduate program acknowledged the course’s heavy workload and its theoretical and abstract nature. They also recognized the importance of having a good memory for effectively navigating the course material. There were no significant differences between the two groups in terms of learning pressure, course comprehension, and the amount of time spent on the course. These findings indicated that while the BOPPPS model positively influenced some aspects of students’ learning experiences and academic performance, it did not drastically alter their overall perceptions of the course’s demands and challenges. The course’s heavy workload and abstract content may remain inherent challenges of otolaryngology education, regardless of the teaching methodology employed. To further enhance the learning experience, future studies could investigate ways to reduce the perceived heavy workload and abstract nature of the course while continuing to utilize the strengths of the BOPPPS model [ 30 , 36 , 37 ]. Implementing additional interactive and hands-on learning opportunities, incorporating practical case studies, and providing tailored support for memory retention could be potential strategies to adopt. Moving forward, educators and institutions can build upon the strengths of the BOPPPS model while exploring additional strategies to optimize students’ learning experiences in otolaryngology.
While this study offered valuable insights, it was important to recognize certain limitations in its design and scope. Firstly, the research focused on a specific group of fourth year undergraduates, potentially limiting the generalizability of the findings to students at different stages of their medical education. Expanding the study to include a more diverse cohort from various educational levels would provide a more comprehensive understanding of the model’s efficacy. Additionally, the study’s single-institution setting and relatively short duration might restrict the applicability of the results to other medical schools. Conducting future research involving multiple institutional settings, larger sample sizes and a longitudinal investigation extending over multiple years would enhance the external validity and enable a broader assessment of the BOPPPS model’s impact. In this study, the survey was designed to capture general aspects of the learning experience applicable to any teaching method, though we recognize the need for refined questions to better address the nuances of each methodology. While students from different classes had their teaching sessions conducted simultaneously to minimize information sharing, the possibility cannot be entirely eliminated. Furthermore, a crossover design was not feasible due to logistical constraints and the structured curriculum, but future research should incorporate this approach for a more direct comparison and to capture the long-term effects of the BOPPPS model on students’ academic performance and perceptions.
In this study, BOPPPS model increased student satisfaction and improved learning outcomes in otolaryngologic medical education by fostering active learning, problem-solving skills, teamwork, analytical thinking, and motivation. This comprehensive approach showed great promise in effectively cultivating future otolaryngologists. Educators and medical institutions should consider adopting similar innovative teaching methodologies to enhance the learning experiences and academic achievements of medical students.
Data is provided within the manuscript or supplementary information files.
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This work was supported by the Natural Science Foundation of Anhui Provincial Education Department (KJ2021A0315).
Dachuan Fan, Chao Wang, Xiumei Qin and Shiyu Qiu contributed equally to this work.
Department of Otorhinolaryngology Head and Neck Surgery, the Second Affiliated Hospital of Anhui Medical University, Hefei, 230601, Anhui Province, China
Dachuan Fan, Xiumei Qin, Shiyu Qiu, Yan Xu & Yatang Wang
Department of Economics and Trade, School of Economics and Management, Hefei University, No. 99 Jinxiu Avenue, Hefei, 230601, Anhui Province, China
Department of Hematology, the Second Affiliated Hospital of Anhui Medical University, NO. 678, Furong Road, Hefei, 230601, Anhui Province, China
Jinxiao Hou
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DC-F designed the study and drafted the manuscript. C-W designed the course evaluation questionnaire. XM-Q, SY-Q, Y-X, and YT-W collected data and assessed examination scores for eligibility. JX-H performed the statistical analysis and supervised the study. All authors critically reviewed and revised the manuscript. All authors read and approved the final manuscript.
Correspondence to Jinxiao Hou .
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This study was conducted following the guidelines of the Helsinki Declaration, and approved by the local Ethics Committee of the Second Affiliated Hospital of Anhui Medical University (YX2024-034). The Ethics Committee of the Second Affiliated Hospital of Anhui Medical University approved all experimental protocols for this study. Each participant voluntarily took part in this study. Informed consent was obtained from all subjects and/or their legal guardian(s).
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Fan, D., Wang, C., Qin, X. et al. Evaluation of the BOPPPS model on otolaryngologic education for five-year undergraduates. BMC Med Educ 24 , 860 (2024). https://doi.org/10.1186/s12909-024-05868-3
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DOI : https://doi.org/10.1186/s12909-024-05868-3
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A model for accelerated aging in mice was developed: CB6F2 mice aged 39-45 days were exposed to fractionated 4-fold relatively uniform γ-radiation ( 137 Cs, 0.98 Gy/min) at a total dose of 6.8 Gy. Radiation exposure led to delayed active growth, leukopenia, and lymphopenia for over 1 year during the post-radiation period. The death of irradiated males and females occurred significantly earlier than in control group animals. Median lifespans in the experimental group were 35-38% lower than in the control group ( p <0.001). Ionizing radiation exposure led to the early development of hair depigmentation, cachexia, and the development of aging-associated diseases. In irradiated mice, oncological pathology constituted 30-35% in the mortality structure, which is twice as often as in the control group. The developed model can be used to study the pathogenesis of accelerated aging under radiation exposure and the search for means of its prevention and treatment.
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E. A. Yakunchikova, M. N. Yurova, E. A. Radetskaya, K. V. Altukhov, A. L. Semenov, A. V. Panchenko, M. L. Tyndyk, V. N. Bykov & E. I. Fedoros
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E. A. Yakunchikova & I. S. Drachyov
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny , Vol. 177, No. 3, pp. 356-361, March, 2024
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Yakunchikova, E.A., Yurova, M.N., Drachyov, I.S. et al. Model of Accelerated Aging in CB6F2 Mice Induced by Ionizing Radiation. Bull Exp Biol Med (2024). https://doi.org/10.1007/s10517-024-06190-0
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Pictured from left are Ottawa County Commissioner Roger Belknap; Joe Moss, who is chair of the Ottawa County Board of Commissioners; and Sylvia Rhodea, who is vice chair of the Ottawa County Board of Commissioners on Nov. 28, 2023. (MLive.com) Cory Morse | [email protected]
GRAND RAPIDS, MI - In 2003, I was a county government reporter in Florida working late one October night when I heard a lot of commotion on the police scanner about an alligator and a child.
I immediately drove the few minutes to the fish camp. It was an emotional and chaotic scene because a 12-year-old boy died after being attacked and pulled underwater by a 10-foot alligator. He had been swimming in the river, about 30 minutes from Orlando, with a couple buddies.
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A top U.N. counterterrorism official has told the Security Council that a vast stretch of Africa could fall under the control of groups affiliated with the Islamic State group and affiliated terrorist groups
UNITED NATIONS -- A top U.N. counterterrorism official told the Security Council on Thursday that a vast stretch of Africa could fall under the control of the Islamic State group and affiliated terrorist organizations .
There was no known link between an alleged plot to attack Taylor Swift shows in Vienna and the group or its affiliates elsewhere in the world, but both suspects appeared to be inspired by the Islamic State group and al-Qaida, Austrian authorities said Thursday.
In a regular report to the council, Vladimir Voronkov , the undersecretary for counterterrorism, told members that IS group affiliates have “expanded and consolidated their area of operations” in West Africa and the Sahel.
A “vast territory stretching from Mali to northern Nigeria could fall under their effective control” if their influence continues, Voronkov said.
He said that IS group affiliates have also expanded operations in other parts of the continent, including parts of Mozambique, Somalia, and the Democratic Republic of the Congo, which saw a “dramatic increase in terrorist attacks” that killed large numbers of civilians.
Voronkov told the council that ISIS-K, the group’s Afghanistan affiliate, has “improved its financial and logistical capabilities” in the last six months and increased recruitment efforts. He said IS has demonstrated its global intent by claiming responsibility for ISIS-K attacks and increasing operations in Iraq and Syria.
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In an unprecedented scenario, Universal Music Group chairman/CEO Lucian and his ascendant son Elliot will control more than a third of the U.S. market — at competing companies.
If your last name is Grainge, you probably oversee a large chunk of the U.S. music business.
Following Elliot Grainge ’s promotion to CEO of Atlantic Music Group effective Oct. 1, the Grainge family— Elliot and his father, Lucian Grainge , chairman/CEO of Universal Music Group (UMG) — will control roughly 37.6% of the U.S. recorded music market, according to Billboard ’s analysis of data from Luminate.
The younger Grainge, whose record label 10K Projects was acquired by UMG competitor Warner Music Group in 2023, will lead a record label group with about 7.9% of the U.S. market’s equivalent album units (EAUs). That includes Atlantic Records, which had a 5.3% share through Aug. 1, along with the remaining labels that comprise Atlantic Music Group — 300 Elektra Entertainment (which includes the labels 300, Elektra, Fueled By Ramen, Roadrunner, Low Country Sound, DTA and Public Consumption) and 10K Projects — with an estimated 2.6% share.
The Grainge’s father-son CEO dynamic is unprecedented even for an industry that often sees the offspring of heavy hitters follow a parent into the business. There have been many family businesses run by successive generations — music publisher peermusic, for example — but never in modern history have a father and son been CEOs of a global music company and a major label music group simultaneously.
Grainge, age 30, will ascend to CEO of Atlantic Music Group as WMG restructures its organizational chart and Atlantic retools to market music to digital natives (a.k.a. young people). CEO Robert Kyncl is “excited by the prospect of taking Atlantic’s culture making capabilities and adding the 10K Projects founder’s digitally native approach into the mix,” he said during Wednesday’s earnings call.
As Billboard reported in February, Atlantic laid off about two dozen staffers with the intention of “bringing on new and additional skill sets in social media, content creation, community building and audience insights,” with the goal of “dial[ing] up our fan focus and help[ing] artists tell their stories in ways that resonate,” Julie Greenwald , the company’s chairman/CEO, said at the time. Greenwald was to assume the new role of chairman upon Grainge’s promotion but announced her resignation on Tuesday (Aug. 6). She will officially step down at the end of January 2025.
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A positive control group is an experimental control that will produce a known response or the desired effect. A positive control is used to ensure a test's success and confirm an experiment's validity. For example, when testing for a new medication, an already commercially available medication could serve as the positive control.
The control group and experimental group are compared against each other in an experiment. The only difference between the two groups is that the independent variable is changed in the experimental group. The independent variable is "controlled", or held constant, in the control group. A single experiment may include multiple experimental ...
A true experiment (a.k.a. a controlled experiment) always includes at least one control group that doesn't receive the experimental treatment.. However, some experiments use a within-subjects design to test treatments without a control group. In these designs, you usually compare one group's outcomes before and after a treatment (instead of comparing outcomes between different groups).
Experimental and control groups are the two main groups found in an experiment, each serving a slightly different purpose. Experimental groups are being manipulated to try and change the out come ...
A control group is not the same thing as a control variable. A control variableor controlled variable is any factor that is held constant during an experiment. Examples of common control variables include temperature, duration, and sample size. The control variables are the same for both the control and experimental groups.
Control group design is fundamental to psychological research, offering a means to measure the effect of a variable by comparing outcomes between treated and untreated groups. This design can take several forms, including post-test only and pretest-posttest configurations, each with its own advantages in minimizing experimental validity threats. The Solomon Four Group Design further enhances ...
Table of Contents control group, the standard to which comparisons are made in an experiment.Many experiments are designed to include a control group and one or more experimental groups; in fact, some scholars reserve the term experiment for study designs that include a control group. Ideally, the control group and the experimental groups are identical in every way except that the experimental ...
This group typically receives no treatment. These experiments compare the effectiveness of the experimental treatment to no treatment. For example, in a vaccine study, a negative control group does not get the vaccine. Positive Control Group. Positive control groups typically receive a standard treatment that science has already proven effective.
Positive control groups: In this case, researchers already know that a treatment is effective but want to learn more about the impact of variations of the treatment.In this case, the control group receives the treatment that is known to work, while the experimental group receives the variation so that researchers can learn more about how it performs and compares to the control.
To test its effectiveness, you run an experiment with a treatment and two control groups. The treatment group gets the new pill. Control group 1 gets an identical-looking sugar pill (a placebo). Control group 2 gets a pill already approved to treat high blood pressure. Since the only variable that differs between the three groups is the type of ...
A control group is a fundamental component of scientific experiments designed to compare and evaluate the effects of an intervention or treatment. It serves as a baseline against which the experimental group is measured. The control group consists of individuals or subjects who do not receive the experimental treatment but are otherwise ...
A control group in a scientific experiment is a group separated from the rest of the experiment, where the independent variable being tested cannot influence the results. This isolates the independent variable's effects on the experiment and can help rule out alternative explanations of the experimental results. Control groups can also be separated into two other types: positive or negative.
A control group is typically thought of as the baseline in an experiment. In an experiment, clinical trial, or other sort of controlled study, there are at least two groups whose results are compared against each other. The experimental group receives some sort of treatment, and their results are compared against those of the control group ...
The control group and experimental group are two essential components of any research study. The main similarity between these groups is that they are both used to assess the effects of a treatment or intervention. The control group is intended to provide a baseline measurement of the outcomes that are expected in the absence of the intervention.
Treatment and control groups. In the design of experiments, hypotheses are applied to experimental units in a treatment group. [1] In comparative experiments, members of a control group receive a standard treatment, a placebo, or no treatment at all. [2] There may be more than one treatment group, more than one control group, or both.
In an experiment, the control is a standard or baseline group not exposed to the experimental treatment or manipulation.It serves as a comparison group to the experimental group, which does receive the treatment or manipulation. The control group helps to account for other variables that might influence the outcome, allowing researchers to attribute differences in results more confidently to ...
The sample would be split into two groups: experimental (A) and control (B). For example, group 1 does 'A' then 'B,' and group 2 does 'B' then 'A.' This is to eliminate order effects. Although order effects occur for each participant, they balance each other out in the results because they occur equally in both groups. 3.
A true experiment (a.k.a. a controlled experiment) always includes at least one control group that doesn't receive the experimental treatment. However, some experiments use a within-subjects design to test treatments without a control group. In these designs, you usually compare one group's outcomes before and after a treatment (instead of ...
In contrast, the control group is identical in every way to the experimental group, except the independent variable is held constant. It's best to have a large sample size for the control group, too. It's possible for an experiment to contain more than one experimental group. However, in the cleanest experiments, only one variable is changed.
A true experiment (aka a controlled experiment) always includes at least one control group that doesn't receive the experimental treatment. However, some experiments use a within-subjects design to test treatments without a control group. In these designs, you usually compare one group's outcomes before and after a treatment (instead of ...
In this experiment, the group of participants listening to no music while working out is the control group. They serve as a baseline with which to compare the performance of the other two groups. The other two groups in the experiment are the experimental groups. They each receive some level of the independent variable, which in this case is ...
Example: Random assignment To divide your sample into groups, you assign a unique number to each participant. You use a computer program to randomly place each number into either a control group or an experimental group. Because of random assignment, the two groups have comparable participant characteristics of age, gender, socioeconomic status ...
What Is a Control Group in an Experiment. A control group is a set of subjects in an experiment who are not exposed to the independent variable. The purpose of a control group is to serve as a baseline for comparison. By having a group that is not exposed to the treatment, researchers can compare the results of the experimental group and determine whether the independent variable had an impact.
In scientific testing, a control group is a group of individuals or cases that is treated in the same way as the experimental group, but that is not exposed to the experimental treatment or factor. Results from the experimental group and control group can be compared. If the control group is treated very similarly to the experimental group, it ...
The control groups that make up its weighted combination must add up to 100%. For example, researchers could decide that one group accounts for 20% and another 80%. A more flexible method might lead to more accurate results, the researchers say, and they've devised one. Their two-step synthetic control approach goes through two stages:
A non-randomized controlled trial was conducted with 167 five-year undergraduate students from Anhui Medical University, who were allocated to an experimental group and a control group. The experimental group received instruction using the BOPPPS model, while the control group underwent traditional teaching methods.
Median lifespans in the experimental group were 35-38% lower than in the control group (p<0.001). Ionizing radiation exposure led to the early development of hair depigmentation, cachexia, and the development of aging-associated diseases. In irradiated mice, oncological pathology constituted 30-35% in the mortality structure, which is twice as ...
GRAND RAPIDS, MI - In 2003, I was a county government reporter in Florida working late one October night when I heard a lot of commotion on the police scanner about an alligator and a child. I ...
A top U.N. counterterrorism official has told the Security Council that a vast stretch of Africa could fall under the control of groups affiliated with the Islamic State group and affiliated ...
The younger Grainge, whose record label 10K Projects was acquired by UMG competitor Warner Music Group in 2023, will lead a record label group with about 7.9% of the U.S. market's equivalent ...