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Sankara nethralaya (unit of medical research foundation).

Sankara Nethralaya Medical Research Foundation

Sankara Nethralaya was established in 1978 by Dr. S. S. Badrinath to offer quality eye care services to the haves and have-nots regardless of their ability to pay. Our mission is to “Be the center of excellence in delivering total eye care for all and spreading knowledge through Education and Training and carrying India centric Research for alleviating visual morbid.”

About 50% of the out-patient department and 35% of the surgeries are done free of cost to the underprivileged. There are 27 operation theatres equipped with the latest equipment in our branches across India to enable the poor and indigent to receive the quality ophthalmic care they deserve. Over the last 40 odd years, over one million patients have been treated from all over India and Asia, earning the moniker of “mecca of eye care in Asia”.

Sankara Nethralaya also conducts screening camps at schools, eye camps for labourers, skilled and unskilled workers, and visits rural areas to screen remote populations. Patients can also walk into our community eye care facilities in Chennai and Kolkata for COST – FREE treatment.

Contact Information

Sankara Nethralaya hospital College Road Thousand Lights West Nungambakkam Chennai Tamil Nadu India

  • Telephone: : +91-44-4227 1500, +91-44-2827 1616
  • e-mail id: : [email protected]

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Medindia » Healthcare Directory » Hospital » Tamil Nadu » Chennai » Medical Research Foundation

Medical Research Foundation, Chennai - Private Hospital

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Medical Research Foundation

Director : Dr. Badrinath. S. S

Address: 18, College Road, Nungambakkam, Chennai - 600006 Tamil Nadu

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merf (1)

Madras ENT Research Foundation (P) Ltd

No-1, Ist Cross Street, Off. II Main Road, Raja Annamalaipuram, Chennai – 600 028.

Phone : + 91 44-24 311 411 / 412 / 413 / 414 / 415  + 91 44-24 311 416

[email protected]

First NABH Accredited ENT Hospital in Tamil Nadu

nabh logo

24 hrs Emergency ENT Care

For emergency please contact +919840228906

The Implantation Otology Course begins from July 1st 2024 for a period of one year in affiliation with The Dr MGR Medical University. Click here to know more..

Starting with an initial bed strength of a mere 6 beds, Madras ENT Research Foundation (MERF) has grown into one of the biggest ENT hospitals in the country. More than the quantitative growth, what has been gratifying for us has been the qualitative growth. The institution has today facilities which can be the envy of many an ENT center in the most advanced countries. Thus Madras ENT Research Foundation has been in the forefront of the Cochlear Implant Scenario in India and today has one of the largest Cochlear Implant clinics in the world. It has also been a pioneer in introducing lasers in the field of Otorhinolaryngology.  Read more

Excellence is a way of life -

The impossible may take a little longer , merf academics.

MERF has to its credit numerous academic achievements...

nabh

NABH accredited Centre

MERF is one of the first to get NABH accredited ENT Hospital in South India...

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Charitable Trust

MERF, Charitable Trust was formed with the idea of rendering yeoman service...

Our Inspiration

Prof S Kameswaran

Prof Shanmugam Kameswaran (1923-2021)

Professor Shanmugam Kameswaran was born in 1923 and did his MBBS and MS at Madras Medical College, India, under Prof. PV Cherian who later became the Governor of Maharashtra, India. He worked as his assistant and left for the UK in the 1950s along with his wife, Dr Lalitha Kameswaran, who went on to do her PhD at the University of London. He had a very close association with his colleagues in the UK and was trained at the Royal National Throat, Nose and Ear Hospital, Gray’s Inn Road, under Prof Maxwell Ellis in the 1950s. He was a friend and compatriot of eminent ENT surgeons in the UK, such as Sir DFN Harrison and John Ballantyne before returning to India serving as Prof of ENT at Madurai medical college and later as Director of the upgraded Institute of Otorhinolaryngology – Head & Neck Surgery (ORL-HNS) at Madras Medical College.  Read more

ci clinic snipet.jpg

MERF has one of the most advanced & experienced Cochlear Implant Clinics in this part of the...

tncmchis snipet.jpg

We have completed more than 1500 CI & 50 ABI under Tamil Nadu Chief Ministers Comprehensive....

hnc snipet.jpg

The Head & Neck Cancer clinic at MERF provides comprehensive treatment and...

merfish.jpg

Merf Institute of Speech & Hearing The goal is a world class institute providing quality education,...

vertigo clinic.jpg

MERF runs a sophisticated Vestibular laboratory with the latest VideoOculography....

ALLERGY CLINIC.jpg

This clinic aims to offer a comprehensive service to diagnose and treat allergic....

SNORING CLINIC.jpg

This clinic evaluates patients with snoring and suggests appropriate treatment...

VOICE CLINIC.jpg

The voice clinic at Madras ENT Research Foundation is dedicated exclusively to the....

SKULL BASE CLINIC.jpg

Skull base surgery is a unique speciality encompassing multidisciplinary treatment..

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Hotels near Madras ENT Research Foundation....

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Photo gallery of various achievements and awards of our Consultants and Post grad...

VIDEO GALLERY.jpg

Video gallery of various surgeries and lectures...

Upcoming Events

IASSA MERF WSD Walkathon 24 March 2024

The 73rd All India Temporal Bone Workshop is to be held on July 20th and 21st 2024. Details of the registration can be found in the academics webpage. ​ The 74th All India Temporal Bone Workshop is to be held on December 7th and 8th 2024. Details of the registration can be found in the academics webpage.

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Sankara Nethralaya, a not-for-profit charitable hospital, embarked on a relentless journey on September 6, 1978 to provide world-class tertiary eye care in India. Its growth since then has been phenomenal - thanks to the unconditional and generous support received from all quarters of society.

It enjoys accreditation by the national board of accreditation for health care providers, (NABH) the highest quality certification in this category in India.

Sankara Nethralaya has its main campus and 4 centers at Chennai of which one is an exclusive community hospital, two major facilities

Tax Benefits - INDIA
To Support Sankara Nethralaya

Donations to are exempt under Section of the Income Tax Act. are exempt under Section of the Income Tax Act.-->

For Online Donation Click Here All Master/Visa Credit And Debit Cards Accepted

Mrs. Vanmathi was only 38 years old when she developed cataract in her right eye. She works as a housemaid to supplement the household income while her husband, Panjanathan, is an unskilled labourer in the building sector.

For More Information -
To Donate

CSR

Last Updated on : 20-09-2023
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Sankara Netralaya Medical Research Foundation - Admission 2024, Fees, Courses, Placement, Ranking

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  • About Sankara Netralaya Medical Research Foundation

Sankara Nethralaya Academy, located in Chennai, is a renowned educational institution that focuses on providing comprehensive knowledge and training in the field of ophthalmology. With its state-of-the-art campus and world-class facilities, the academy offers a wide range of courses to aspiring students.

The academy offers various courses including Bachelor of Optometry (B.Optom), Master of Optometry (M.Optom), Diploma in Ophthalmic Nursing Assistant (DONA), and Fellowship programs in various specializations. Each course has a limited number of seats available, ensuring personalized attention and quality education.

The campus is equipped with advanced laboratories, well-stocked libraries, modern classrooms, and cutting-edge technology to facilitate effective learning. The academy also provides excellent placement and recruitment opportunities, with tie-ups with leading eye care hospitals and organizations. Students graduating from Sankara Nethralaya Academy have a high employability rate and are highly sought after in the industry.

Additionally, the academy offers scholarships to deserving students based on their academic performance and financial need. These scholarships aim to support and encourage talented individuals to pursue their education in the field of ophthalmology.

The major USPs of Sankara Nethralaya Academy include its prestigious reputation, experienced faculty, strong industry connections, practical training opportunities, and emphasis on research and innovation. The academy is committed to producing skilled professionals who can contribute to the field of eye care and make a positive impact on society.

Table of Contents

Sankara netralaya medical research foundation highlights, sankara netralaya medical research foundation courses and admission 2024, sankara netralaya medical research foundation campus facilities and infrastructure, sankara netralaya medical research foundation scholarships, sankara netralaya medical research foundation eligibility 2024, sankara netralaya medical research foundation related news, explore nearby colleges, fee details of popular colleges, similar colleges.

  • Wide range of academic programs and courses
  • Research opportunities
  • Guest lectures and seminars
  • Workshops and conferences
  • Sports teams and clubs
  • Art and music clubs
  • Drama and theater groups
  • Debating and public speaking clubs
  • Student clubs and organizations
  • Cultural festivals and events
  • Social gatherings and parties
  • Campus events and celebrations
  • Community service projects
  • Volunteer opportunities with local organizations
  • Charity drives and campaigns
  • Service-learning programs
  • Internship placements
  • Job fairs and recruitment events
  • Part-time job opportunities on and off campus
  • Career development workshops
  • Student government and leadership positions
  • Club and organization leadership roles
  • Leadership development programs
  • Mentorship programs
  • International student associations
  • Cultural festivals and showcases
  • Diversity workshops and discussions
  • Language exchange programs
  • Peer tutoring programs
  • Writing and math centers
  • Study groups and study skills workshops
  • Academic advising services
  • Health clinics and counseling services
  • Fitness centers and sports facilities
  • Wellness workshops and programs
  • Yoga and meditation classes
  • Photography and art clubs
  • Gardening and nature clubs
  • Cooking and baking workshops
  • Music and dance groups
  • Networking events and career fairs
  • Alumni mentorship programs
  • Alumni guest speakers and panels
  • Alumni association and chapters
  • Personal growth workshops
  • Leadership training programs
  • Time management and stress reduction workshops
  • Goal-setting and self-reflection activities
  • Concerts and music performances
  • Theater plays and dance performances
  • Movie screenings and film festivals
  • Art exhibitions and cultural showcases
  • Sankara Nethralaya Academy Chennai offers scholarships to its students at various levels.
  • National Scholarships:
  • Central Sector Scheme of Scholarships for College and University Students: This scholarship is awarded by the Ministry of Human Resource Development, Government of India, to meritorious students from low-income families.
  • Post Matric Scholarships Scheme for Minorities: This scholarship is offered by the Ministry of Minority Affairs, Government of India, to students belonging to minority communities.
  • Merit Cum Means Scholarship for Professional and Technical Courses CS: This scholarship is provided by the Ministry of Minority Affairs, Government of India, to students pursuing professional and technical courses.
  • State Scholarships:
  • Tamil Nadu State Government Scholarship: The Government of Tamil Nadu offers various scholarships to students based on their category, such as BC, MBC, SC, ST, and economically weaker sections.
  • Institute Level Scholarships:
  • Sankara Nethralaya Scholarships: The institute offers scholarships to deserving students based on their academic performance and financial need.
  • Merit Scholarships: These scholarships are awarded to students who have excelled in their academic performance.
  • Need-based Scholarships: Sankara Nethralaya provides scholarships to students who come from economically disadvantaged backgrounds.

Sankara Netralaya Medical Research Foundation PGD Eligibility 2024

Sankara Nethralaya Academy in Chennai offers various postgraduate diploma programs in the field of healthcare and eye care. The admission process and eligibility criteria for these programs are as follows:

  • Candidates must have completed their Bachelor's degree in any relevant field from a recognized university.
  • Applicants must have obtained a minimum aggregate score of 50% in their undergraduate studies.
  • For certain specialized programs, specific eligibility criteria may be required, which can be checked on the official website of Sankara Nethralaya Academy.
  • Interested candidates can apply for the postgraduate diploma programs online through the official website of Sankara Nethralaya Academy.
  • Applicants are required to fill out the application form with accurate personal and academic details.
  • Along with the application form, candidates must submit the necessary documents, including mark sheets, certificates, and proof of identity.
  • After the submission of the application, eligible candidates will be shortlisted based on their academic performance and relevant experience, if any.
  • Shortlisted candidates will then be called for a personal interview or entrance examination, depending on the program applied for.
  • Final selection will be based on the candidate's performance in the interview or entrance examination.
  • Selected candidates will be notified through email or post, and they will be required to complete the admission formalities within the given time frame.

It is important for applicants to regularly check the official website of Sankara Nethralaya Academy for any updates or changes in the admission process and eligibility criteria.

Sankara Netralaya Medical Research Foundation MS (Surgery) Eligibility 2024

The admission process and eligibility criteria to take admission in the M.S. (Master of Surgery) program at Sankara Netralaya Medical Research Foundation Chennai are as follows:

Eligibility Criteria:

  • Applicants must have completed their MBBS degree or an equivalent qualification recognized by the Medical Council of India.
  • They must have completed a compulsory rotating internship before the start of the academic year.
  • Candidates must be registered with the State Medical Council or the Medical Council of India.
  • They must have obtained a minimum aggregate score of 50% in their MBBS degree.

Admission Process:

  • Interested candidates need to submit their application forms along with the required documents to the Sankara Nethralaya Academy.
  • Applicants are shortlisted based on their academic qualifications and performance in the entrance examination conducted by the institution.
  • Shortlisted candidates are then called for a personal interview and counseling session.
  • The final selection is based on the candidate's performance in the interview, academic record, and availability of seats.
  • Selected candidates are notified of their admission and are required to complete the necessary admission formalities within the given time frame.

It is important for applicants to carefully review and fulfill the eligibility criteria to increase their chances of admission to the M.S. program at Sankara Netralaya Medical Research Foundation Chennai.

Admission Updates for 2024

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Sankara Netralaya Medical Research Foundation Chennai

Low Fees MBBS Colleges

Find Sankara Netralaya Medical Research Foundation Chennai, Chennai, Tamil Nadu Hostel Facilities, Cut off, Infrastructure, Course Fees, Hospital, Internship, Admission Procedure, Available Courses, Ranking details for NEET Counselling.

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Quick Summary

Established 1982
Institution Type Private
Affiliated University The Tamilnadu Dr. MGR Medical University,Chennai
Post Graduate Courses 1
Super Speciality Courses
Total Beds
Average Patients
Details
Address No 58/159, Sri Rama Building, Greams Rd, near Apollo Heart Hospital, Thousand Lights, Chennai, Tamil Nadu 600006
Official Website
Contact 044 – 28272727, 044 – 42271500

Sankara Netralaya Medical Research Foundation Chennai Building

Introduction

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PG Courses ▼

Admission to Diploma(DIP),Doctor of Medicine(MD), Master of Surgery(MS) available in Sankara Netralaya Medical Research Foundation Chennai are based on the NEET PG entrance exam conducted by NBE .Doctors can take admission through AIQ counselling (50% of MD/MS seats) or through Tamil Nadu counselling (50% MD/MS Seats).

Sankara Netralaya Medical Research Foundation Chennai PG Seats and Tuition Fees

Find Sankara Netralaya Medical Research Foundation Chennai course wise fees seats and ranking for PG course. ■ – Denotes Course Ranking, ■ – Denotes Course Seats, ■ – Denotes Government Fees, ■ – Denotes Management Fees, ■ – Denotes NRI/OCI Fees.

Course Details
MS OPHTHALMOLOGY
4

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Sankara Netralaya Medical Research Foundation Chennai PG Bond Details and Monthly Stipend ▼

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Sankara Nethralaya Medical Research Foundation, Chennai College Chennai

College Name
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Facilities Offered Theatre Laboratory Computer Center Guest House Solar Power
College Type Affiliated College
University Name Tamil Nadu Dr. M.G.R. Medical University , Chennai
University Type State Public University
Established Year 1978
Statutory Body Medical Council of India
Management Private Un-Aided
Specialized medical-others
Location Type Urban
Girls Only No
Staff Quarter 22
Hostel Intake 15
Male Teachers 6
Female Teachers 12
Total Teachers 18
Male Staff 3
Female Staff 2
Total Staff 5
Playground No
Theatre Yes
Laboratory Yes
Health Center No
Indoor Stadium No
Computer Center Yes
Guest House Yes
Solar Power 1
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Provisional Rating 4.7/5 Based on 9 ratings by visitors
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Humidity 58%
Max Temp 36.67 °C
Min Temp 34.99 °C
Sunrise 5:42 AM
Sunset 6:35 PM
Wind Speed 18.504 km/h
Visibility 7 km
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Vision Research Foundation

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+91-44-42271500

[email protected]

medical research foundation chennai

Prof N Angayarkanni, PhD

Professor & Head Department of Biochemistry and Cell Biology

medical research foundation chennai

After my teaching profession for graduate students in Biochemistry for 7 years pursued a research career in Ocular Biochemistry in the Department of Biochemistry and Cell Biology, Vision Research foundation (since 2002).

In addition, acting as Quality Manager in SNSC clinical Laboratory services, Medical Research Foundation at SankaraNethralaya, Chennai (Honorary service).

My research work focuses on delineating mechanistic pathways of ocular diseases using cell based models and clinical studies. This is to understand the etiopathogensis of specific ocular diseases and to identify drug targets for intervention. The work also focusses on characterizing potential therapeutic molecules including ayurvedic principles of Triphala.

medical research foundation chennai

PubMed link

https://www.ncbi.nlm.nih.gov/pubmed/?term=Narayanasamy+Angayarkanni

Education :

M.Sc, M.phil& PhD – Medical Biochemistry, (1996), DR.ALMPGIBMS, University of Madras B.Sc Biochemistry at Avinashilingam Home science college, Coimbatore Publications: 53 Book Chapters: 4 Book: 1 Patent: 1; Filed:1 Guided 5Ph.D students 60 post graduated Dissertations Completed projects: As PI is15 On going :3

Biomarker discovery : Towards diagnostic

  • Tear based clinical proteomics for Biomarker discovery towards early diagnosis and treatment of Dry Eye Syndrome. Currently focusing to characterize candidate biomarkers.
  • Prognostic and early markers for development of Diabetic retinopathy in type 2 Diabetes mellitus

Delineating disease pathogenesis for novel drug targets :

  • Protective role of HDL associated anti-oxidant Paroxonase enzyme in the retinal barrier cell : what happens in AMD?
  • Elastosis defect in understanding the pathology of Pseudoexfoliation syndrome.
  • Steven Johnson syndrome : Inflammatory cytokines and fibrosis in the ocular surface.

Characterization of potential therapeutic Ayurvedic principle compounds / aminoacids

  • Signaling mechanism of Triphala active principles that showed characteristic anti-fibrotic, anti-angiogenic and anti-inflammatory activities based on retinal barrier cell and vascular cell based models.
  • Signaling mechanism of amino acids in potentiating GLUT4 mediated glucose uptake and mechanism of action of amino acids in ameliorating the retinal changes in Diabetic retinopathy.

Google Scholar : Check out this link

  • Rebecca, M., Gayathri, R., Bhuvanasundar, R., Sripriya, K., Shantha, B., & Angayarkanni, N*. (2018). Elastin modulation and modification by homocysteine: a key factor in the pathogenesis of Pseudoexfoliation syndrome?. British Journal of Ophthalmology, bjophthalmol-2018. DOI: 10.1136/2018 - 312088
  • Shanmuganathan, S., & Angayarkanni, N*. (2019). Chebulagic acid and Chebulinic acid inhibit TGF-β1 induced fibrotic changes in the chorio-retinal endothelial cells by inhibiting ERK phosphorylation. Microvascular research, 121, 14-23. DOI: 10.1016/j.mvr.2018.09.001.
  • Iyer, G., Agarwal, S., Srinivasan, B., & Narayanasamy, Angayarkanni. (2018). Isolation of acid from eye drop bottles being used by patients presenting with presumed scleritis. Indian journal of ophthalmology, 66(8), 1084. DOI: 10.4103/ijo.IJO_82_18.
  • Shanmuganathan, S., & Angayarkanni, N*. (2018). Chebulagic acid Chebulinic acid and Gallic acid, the active principles of Triphala, inhibit TNFα induced pro-angiogenic and pro-inflammatory activities in retinal capillary endothelial cells by inhibiting p38, ERK and NFkB phosphorylation. Vascular pharmacology. DOI: 10.1016/j.vph.2018.04.005.
  • Srividya, G., Jain, M., Mahalakshmi, K., Gayathri, S., Raman, R., & Angayarkanni, N*. (2018). A novel and less invasive technique to assess cytokine profile of vitreous in patients of diabetic macular oedema. Eye, 32(4), 820. DOI: 10.1038/eye.2017.285.
  • Muralikumar, S., Vetrivel, U., Narayanasamy, Angayarkanni., & Das, U. N. (2017). Probing the intermolecular interactions of PPARγ-LBD with polyunsaturated fatty acids and their anti-inflammatory metabolites to infer most potential binding moieties. Lipids in health and disease, 16(1), 17. 10.1186/s12944-016-0404-3.
  • Selvi, R., Bhuvanasundar, R., & Angayarkanni, N*. (2017). Amino Acid Mixture Acts as a Potent VEGF Lowering Agent in CHO-K1 Cells Exposed to High Glucose. Archives of medical research, 48(3), 238-246. DOI: 10.1016/j.arcmed.2017.05.001.
  • Gurumurthy, S., Iyer, G., Srinivasan, B., Agarwal, S., & Angayarkanni, N*. (2018). Ocular surface cytokine profile in chronic Stevens-Johnson syndrome and its response to mucous membrane grafting for lid margin keratinisation. British Journal of Ophthalmology, 102(2), 169-176. DOI: 10.1136/bjophthalmol-2017-310373
  • Indhushree, R., Monica, R., Coral, K., Angayarkanni, N., Punitham, R., Subburathinam, B. M., ... & Santanam, P. P. (2016). Visual functions of workers exposed to organic solvents in petrochemical industries. Indian journal of occupational and environmental medicine, 20(3), 133. DOI: 10.4103/0019-5278.203138.
  • Aluru, S. V., Shweta, A., Bhaskar, S., Geetha, K., Sivakumar, R. M., Utpal, T, Prema P, Sivakumar M. & Angayarkanni, N*. (2017). Tear fluid protein changes in dry eye syndrome associated with rheumatoid arthritis: a proteomic approach. The ocular surface, 15(1), 112-129. DOI: 10.1016/j.jtos.2016.09.005.
  • AnandBabu, K., Bharathidevi, S. R., Sripriya, S., Sen, P., Prakash, V. J., Bindu, A.Viswanathan N & Angayarkanni, N*. (2016). Serum Paraoxonase activity in relation to lipid profile in Age-related Macular Degeneration patients. Experimental eye research, 152, 100-112. DOI: 10.1016/j.exer.2016.09.009.
  • Gayathri, R., Coral, K., Sharmila, F., Sripriya, S., Sripriya, K., Manish, P., ... & Narayanasamy, Angayarkanni*. (2016). Correlation of aqueous humor Lysyl oxidase activity with TGF-ß levels and LOXL1 genotype in Pseudoexfoliation. Current eye research, 41(10), 1331-1338. DOI: 10.3109/02713683.2015.1125505.
  • Sivasankar, S., Lavanya, R., Brindha, P., & Angayarkanni, N*. (2015). Aqueous and alcoholic extracts of Triphala and their active compounds chebulagic acid and chebulinic acid prevented epithelial to mesenchymal transition in retinal pigment epithelial cells, by inhibiting SMAD-3 phosphorylation. PloS one, 10(3), e0120512. DOI: 10.4103/ijmr.IJMR_1583_15.
  • Bharathidevi, S. R., Babu, K. A., Jain, N., Muthukumaran, S., Umashankar, V., Biswas, J., & Angayarkanni, N*. (2017). Ocular distribution of antioxidant enzyme paraoxonase & its alteration in cataractous lens & diabetic retina. The Indian journal of medical research, 145(4), 513. DOI: 10.4103/ijmr.IJMR_1284_14..
  • Bharathselvi, M., Biswas, S., Raman, R., Selvi, R., Coral, K., Narayanansamy, Angayarkanni, Ramakrishnan S & Sulochana, K. N. (2016). Homocysteine & its metabolite homocysteine-thiolactone & deficiency of copper in patients with age related macular degeneration-A pilot study. The Indian journal of medical research, 143(6), 756. DOI: 10.4103/0971-5916.192026.
  • Kaviarasan, K., Jithu, M., Mulla, M. A., Sharma, T., Sivasankar, S., Das, U. N., & Angayarkanni, N*. (2015). Low blood and vitreal BDNF, LXA4 and altered Th1/Th2 cytokine balance are potential risk factors for diabetic retinopathy. Metabolism, 64(9), 958-966. DOI: 10.1016/j.metabol.2015.04.005.
  • Bharathi Devi, S. R., Coral, K., Sulochana, K. N., & Angayarkanni, N*. (2015). Free Amino Acids Glycine and Glutamic Acid Inhibit Angiogenesis Induced by AGE in Bovine Retinal Endothelial Cells. J Glycomics Lipidomics 5: 130. doi: 10.4172/2153-0637.1000130 DOI: 10.4172/2153-0637.1000130.
  • Coral, K., Madhavan, J., Pukhraj, R., & Angayarkanni, N*. (2013). High glucose induced differential expression of lysyl oxidase and its isoform in ARPE-19 cells. Current eye research, 38(1), 194-203. DOI: 10.3109/02713683.2012.720341.
  • Arora, B., Narayanasamy Angayarkanni., Nirmal, J., Halder, N., Patnaik, S., Ravi, A. K., & Velpandian, T. (2014). Development and validation of a LC–MS/MS method for homocysteine thiolactone in plasma and evaluation of its stability in plasma samples. Journal of Chromatography B, 944, 49-54. DOI: 10.1016/j.jchromb.2013.11.011.
  • Jasna, J. M., Anandbabu, K., Bharathi, S. R., & Angayarkanni, N*. (2014). Paraoxonase enzyme protects retinal pigment epithelium from chlorpyrifos insult. PloS one, 9(6), e101380. DOI: 10.1371/journal.pone.0101380.
  • Sivasankar, S., Lavanya, R., Brindha, P., & Angayarkanni, N*. (2015). Aqueous and alcoholic extracts of Triphala and their active compounds chebulagic acid and chebulinic acid prevented epithelial to mesenchymal transition in retinal pigment epithelial cells, by inhibiting SMAD-3 phosphorylation. PloS one, 10(3), e0120512. DOI: 10.1371/journal.pone.0120512.
  • Agarwal, S., Angayarkanni, N., Iyer, G., Srinivasan, B., Natarajan, R., Charola, S., ... & Padmanabhan, P. (2014). Clinico-biochemical correlation of the effect of subconjunctival bevacizumab for corneal neovascularization. Cornea, 33(10), 1016-1021. DOI: 10.1097/ICO.0000000000000198.
  • Biswas, J., Ravi, R. K., Naryanasamy, Angayarkanni., Kulandai, L. T., & Madhavan, H. N. (2013). Eales' disease-current concepts in diagnosis and management. Journal of ophthalmic inflammation and infection, 3(1), 11. DOI: 10.1186/1869-5760-3-11.
  • Aluru, Saijyothi. V., Agarwal, S., Srinivasan, B., Iyer, G. K., Rajappa, S. M., Tatu, U, Prema P, Nirmala S & Narayanasamy, Angayarkanni*. (2012). Lacrimal proline rich 4 (LPRR4) protein in the tear fluid is a potential biomarker of dry eye syndrome. PloS one, 7(12), e51979. DOI: 10.1371/journal.pone.0051979.
  • Bharathselvi, M., Biswas, J., Selvi, R., Coral, K., Narayanasamy, Angayarkanni., Ramakrishnan, S., & Sulochana, K. N. (2013). Increased homocysteine, homocysteine-thiolactone, protein homocysteinylation and oxidative stress in the circulation of patients with Eales’ disease. Annals of clinical biochemistry, 50(4), 330-338.
  • Vetrivel, U., Ravichandran, S. B., Kuppan, K., Mohanlal, J., Das, U. N., & Narayanasamy Angayarkanni*. (2012). Agonistic effect of polyunsaturated fatty acids (PUFAs) and its metabolites on brain-derived neurotrophic factor (BDNF) through molecular docking simulation. Lipids in health and disease, 11(1), 109. DOI: 10.1186/1476-511X-11-109.
  • Selvi, R., Bhuvanasundar, R., Saijyothi, A. V., Sulochana, K. N., & Angayarkanni, N*. (2012). Amino acids potentiate insulin signaling in CHO-K1 at high glucose conditions. Archives of medical research, 43(3), 173-182. DOI: 10.1016/j.arcmed.2012.04.008.
  • Devi, S. R. B., Suganeswari, G., Sharma, T., Thennarasu, M., & Angayarkanni, N*. (2012). Homocysteine induces oxidative stress in young adult central retinal vein occlusion. British Journal of Ophthalmology, bjophthalmol-2011. DOI: 10.1136/bjophthalmol-2011-301370.
  • Saijyothi, A. V., Fowjana, J., Madhumathi, S., Rajeshwari, M., Thennarasu, M., Prema, P., & Angayarkanni, N*. (2012). Tear fluid small molecular antioxidants profiling shows lowered glutathione in keratoconus. Experimental eye research, 103, 41-46. DOI: 10.1016/j.exer.2012.07.010.
  • Selvi, R., Angayarkanni, N*., Biswas, J., & Ramakrishnan, S. (2011). Total antioxidant capacity in Eales’ disease, uveitis & cataract. The Indian journal of medical research, 134(1), 83.
  • Barathi, S., Charanya, M., Muthukumaran, S., Angayarkanni, N*., & Umashankar, V. (2010). Comparative modeling of PON2 and analysis of its substrate binding interactions using computational methods. Journal of ocular biology, diseases, and informatics, 3(2), 64-72. DOI: 10.1007/s12177-011-9057-7.
  • Barathi, S., Angayarkanni, N*., & Sumantran, V. N. (2010). GLUT-1 expression in bovine retinal capillary endothelial cells and pericytes exposed to advanced glycation end products. Investigative ophthalmology & visual science, 51(12), 6810-6814. DOI: 10.1167/iovs.10-5312.
  • Saijyothi, A. V., Angayarkanni, N*., Syama, C., Utpal, T., Shweta, A., Bhaskar, S.Thennarasu,M Rajappa S & Prema, P. (2010). Two dimensional electrophoretic analysis of human tears: collection method in dry eye syndrome. Electrophoresis, 31(20), 3420-3427. DOI: 10.1002/elps.201000271.
  • Verma, A., Biswas, J., Radhakrishnan, S., & Narayanasamy, A. (2010). Intra-ocular expression of vascular endothelial growth factor (VEGF) and pigment epithelial-derived factor (PEDF) in a case of Eales’ disease by immunohistochemical analysis: a case report. International ophthalmology, 30(4), 429-434. DOI: 10.1007/s10792-009-9338-3.
  • Selvi, R., Angayarkanni, N*., Asma, B., Seethalakshmi, T., & Vidhya, S. (2010). Amino acids influence the glucose uptake through GLUT4 in CHO-K1 cells under high glucose conditions. Molecular and cellular biochemistry, 344(1-2), 43-53. DOI: 10.1007/s11010-010-0527-1.
  • Barathi, S., Angayarkanni, N*., Pasupathi, A., Natarajan, S. K., Pukraj, R., Dhupper, M., ... & Sivashanmugham, M. (2010). Homocysteinethiolactone and paraoxonase: novel markers of diabetic retinopathy. Diabetes care, 33(9), 2031-2037. DOI: 10.2337/dc10-0132.
  • Angayarkanni, N*., Selvi, R., Pukhraj, R., Biswas, J., Bhavesh, S. J., & Tombran-Tink, J. (2009). Ratio of the vitreous vascular endothelial growth factor and pigment epithelial-derived factor in Eales disease. Journal of ocular biology, diseases, and informatics, 2(1), 20-28. DOI: 10.1007/s12177-009-9017-7.
  • Venkata, S. J. A., Narayanasamy, Angayarkanni*., Srinivasan, V., Iyer, G. K., Sivaramakrishnan, R., Subramanian, M., & Mahadevan, Rajeshwari. (2009). Tear ascorbic acid levels and the total antioxidant status in contact lens wearers: a pilot study. Indian journal of ophthalmology, 57(4), 289. DOI: 10.4103/0301-4738.53054.
  • Jaichandran, V. V., Angayarkanni, N., Karunakaran, C., Bhanulakshmi, I. M., & Jagadeesh, V. (2008). Diffusion of Lidocaine buffered to an optimal pH across the Endotracheal tube cuff-An in-Vitro study. Indian Journal of Anaesthesia, 52(5), 536.
  • Coral, K., Angayarkanni, N*, Gomathy, N., Bharathselvi, M., Pukhraj, R., & Rupak, R. (2009). Homocysteine levels in the vitreous of proliferative diabetic retinopathy and rhegmatogenous retinal detachment: its modulating role on lysyl oxidase. Investigative ophthalmology & visual science, 50(8), 3607-3612. DOI: 10.1167/iovs.08-2667.
  • Coral, K., Angayarkanni, N*., Madhavan, J., Bharathselvi, M., Ramakrishnan, S., Nandi, K., ... & Krishnakumar, S. (2008). Lysyl oxidase activity in the ocular tissues and the role of LOX in proliferative diabetic retinopathy and rhegmatogenous retinal detachment. Investigative ophthalmology & visual science, 49(11), 4746-4752. DOI: 10.1167/iovs.07-1550.
  • Angayarkanni, N*., Barathi, S., Seethalakshmi, T., Punitham, R., Sivaramakrishna, R., Suganeswari, G., & Tarun, S. (2008). Serum PON1 arylesterase activity in relation to hyperhomocysteinaemia and oxidative stress in young adult central retinal venous occlusion patients. Eye, 22(7), 969. DOI: 10.1038/sj.eye.6703062.
  • Selvi, R., Angayarkanni, N., Bharathselvi, M., Sivaramakrishna, R., Anisha, T., Jyotirmoy, B., & Vasanthi, B. (2007). Increase in Fe3+/Fe2+ ratio and iron-induced oxidative stress in Eales disease and presence of ferrous iron in circulating transferrin. Current eye research, 32(7-8), 677-683. DOI: 10.1080/02713680701486402.
  • Barathi, S., Vadhana, P., Angayarkanni, N*., & Ramakrishnan, S. (2007). Estimation of hydrogen sulphide in the human lymphocytes. IJBB 44(3) (2007) 179-182.
  • Narayanasamy, A*., Subramaniam, Barathi., Karunakaran, Coral., Ranganathan, Punitham., Sivaramakrishnan, R., Sharma, T., Vasanthi S & Roy, Joseph. (2007). Hyperhomocysteinemia and low methionine stress are risk factors for central retinal venous occlusion in an Indian population. Investigative ophthalmology & visual science, 48(4), 1441-1446. DOI: 10.1167/iovs.06-0905.
  • Ramakrishnan, S., Sulochana, K. N., Lakshmi, S., Selvi, R., & Angayarkanni, N. (2006). Biochemistry of homocysteine in health and diseases.
  • Coral, K., Raman, R., Rathi, S., Rajesh, M., Sulochana, K. N., Angayarkanni, N., ... & Ramakrishnan, S. (2006). Plasma homocysteine and total thiol content in patients with exudative age-related macular degeneration. Eye, 20(2), 203. DOI: 10.1038/sj.eye.6701853.
  • Sulochana, K. N., Ramprasad, S., Coral, K., Lakshmi, S., Punitham, R., Narayanasamy, Angayarkanni., & Ramakrishnan, S. (2003). Glycation and glycoxidation studies in vitro on isolated human vitreous collagen. Medical Science Monitor, 9(6), BR220-BR224.
  • Angayarkanni, N., & Selvam, R. (1999). Effect of γ-Glutamyl Carboxylation of Renal Microsomes on Calcium Oxalate MonohydrateCrystal Binding in Hyperoxaluria. Nephron, 81(3), 342-346. DOI: 10.1159/000045303.
  • Angayarkanni, N., & Selvam, R. (1998). Enhanced renal vitamin-K-dependent gamma-glutamyl carboxylase activity in experimental rat urolithiasis. European urology, 33(1), 116-120. DOI: 10.1159/000019523.
  • Selvam, R., Angayarkanni, N., & Vijaya, R. (1996). NUCLEAR OXALATE BINDING PROTEINS OF RAT LIVER NUCLEI: A PRELIMINARY REPORT. Medical science research, 24(4). DOI: ..
  • Selvam, R., Subramanian, L., Gayathri, R., & Angayarkanni, N. (1995). The anti-oxidant activity of turmeric (Curcuma longa). Journal of ethnopharmacology, 47(2), 59-67. DOI: 10.1016/0378-8741(95)01250-H.

2011 SwarnalathaPunshi Award for the Best Basic Science Researcher at Vision Research Foundation

2010 ICMR overseas fellowship for Biomedical scientists done at Univ of New Mexico. USA

2013 DBT-CETP Travel fellowship 2013 for attending ARVO meeting at Seattle, USA

2007 Allergan Travel fellowship : ASIA -ARVO 2007 at Singapore

1996 Awarded the Research Associate ship by CSIR

1994 Received the PGIBMS Award-Gold Medal for Best Paper presentation at the Indian Association of Biomedical Scientists

1994 Received Senior Research Fellowship by the CSIR

1993 Young Scientist Award by the Urolithiasis Society of India

1992 Qualified CSIR-UGC National Level Test for eligibility for Lectureship in Life Sciences in University / Colleges

1990 Awarded GATE Scholarship in life sciences ( 91 percentile) as JRF to do Ph.D. in a major project approved by the University Grants Commission (UGC)

Post Doctoral Fellows

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Dr Mani Novartis (current)

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Dr Srivdiya Gurumurthy

Dr Kaviarasan K

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Mr Vignesh ICMR 2018 (current)

Ms Sneha CSIR 2017 (current)

Mr Sivasankar S CSIR 2013

Ms Jasna M ICMR 2010

Mr Jithu M DBT 2010

Ms. Sai jyothi A V DBT 2008

Ms Barathi Devi S ICMR 2006

Ms Selvi R DST 2005, 2009

Ms K Coral DBT 2005

Project JRF

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Ms. Vijayvani DST-SERB 2017 (current)

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Mr. Anandbabu DBT 2011

Mr Sanket C ICMR 2012

Ms Sivasankari

Mr Sivasankar S CSIR 2010

Ms Gayathri R ICMR 2008

INSPIRE Fellow

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Ms.Rebecca M DST Fellowship 2015 (current)

Project Assistant

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Ms.Nandhini Novartis 2018 (current)

On going : PhD students

Mr Anandbabu (SASTRA Univ)

Ms Rebecca (TN MGR Med Univ)

Completed Ph.D

Dr. Coral K BITS Pilani 2008

Dr Barathi Devi S R BITS Pilani 2010

Dr Selvi R BITS Pilani 2012

Dr Saijyothi A V BITS Pilani 2013

Dr Sivasankar S SASTRA Thanjavur 2018

Dr N Angayarkanni, PhD Professor and Head RS Mehta Jain Department of Biochemistry and Cell Biology Vision Research Foundation, 41/18 College Road, Nungambakkam Chennai – 600 006. Ph: +91-(044) 28271616 Extn: 1341 / 1301 Email: [email protected]

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A Disease That Makes Children Age Rapidly Gets Closer to a Cure

Progress in the quest to help progeria patients suggests that gene editing techniques may help treat other ultrarare conditions.

John Tacket sits at a lectern and speaks to reporters during a news conference, wearing a cap on his head as Dr. Francis Collins smiles in the background.

By Gina Kolata

A cure for an ultrarare disease, progeria, could be on the horizon. The disease speeds up aging in children and dramatically shortens their lives. But, until recently, there was no path toward a highly effective treatment.

Now, a small group of academics and government scientists, including Dr. Francis Collins, the former director of the National Institutes of Health, is working with no expectation of financial gain to halt progeria in its tracks with an innovative gene editing technique.

If gene editing is effective in slowing or halting progeria, researchers say, the method may also help to treat other rare genetic diseases that have no treatments or cures and, like progeria, have aroused little interest from drug companies.

After a quarter-century of research, the group is approaching manufacturers and planning to seek approval from regulators for a clinical trial on progeria gene editing.

The project “has merit, but also risk,” said Dr. Kiran Musunuru, a gene editing researcher at the University of Pennsylvania, who also advises a gene editing company. He cautioned that although the editing worked well in mice, there is no guarantee that it will work in human patients.

Dr. Collins first became interested in progeria while he was training in medical genetics at Yale University in 1982, almost three decades before he was appointed to lead the N.I.H. One day, he saw a new patient, Meg Casey . She was less than four feet tall, hairless under her wig and wrinkled like an older woman. She was only in her 20s.

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Postleitzahl 140050 - Kraskowo, Oblast Moskau

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  17. Online Appointment

    Chennai - 600 006, Tamil Nadu , India. Telephone: +91-44-42271500, +91-44-2827 1616 e-mail id: [email protected], [email protected] Sankara Nethralaya JKCN 21, Dr.S.S.Badrinath Road, Chennai - 600 006 Telephone: +91-44-42271500, +91-44-2827 1616 e-mail id : [email protected] Sankara Nethralaya CU Shah Eye Hospital

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    Jagadguru Kanchi Sri Chandrasekarendra Saraswathi Nethra Nilayam (JKCN) is one of the Annexes of SANKARA NETHRALAYA situated at 21 Dr.S.S.Badrinath Road, Chennai - 6. HTP Block: Comprising of six floors is exclusively for paying patients. There are 5 consultants Rooms and 6 work-up rooms. Optometrists, post graduates use the work-up rooms for ...