importance of control group in an experiment

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What Is a Control Group?

Control Groups vs. Experimental Groups in Psychology Research

Doug Corrance/The Image Bank/Getty Images

Control Group vs. Experimental Group

Types of control groups.

In simple terms, the control group comprises participants who do not receive the experimental treatment. When conducting an experiment, these people are randomly assigned to this group. They also closely resemble the participants who are in the experimental group or the individuals who receive the treatment.

Experimenters utilize variables to make comparisons between an experimental group and a control group. A variable is something that researchers can manipulate, measure, and control in an experiment. The independent variable is the aspect of the experiment that the researchers manipulate (or the treatment). The dependent variable is what the researchers measure to see if the independent variable had an effect.

While they do not receive the treatment, the control group does play a vital role in the research process. Experimenters compare the experimental group to the control group to determine if the treatment had an effect.

By serving as a comparison group, researchers can isolate the independent variable and look at the impact it had.

The simplest way to determine the difference between a control group and an experimental group is to determine which group receives the treatment and which does not. To ensure that the results can then be compared accurately, the two groups should be otherwise identical.

Not exposed to the treatment (the independent variable)

Used to provide a baseline to compare results against

May receive a placebo treatment

Exposed to the treatment

Used to measure the effects of the independent variable

Identical to the control group aside from their exposure to the treatment

Why a Control Group Is Important

While the control group does not receive treatment, it does play a critical role in the experimental process. This group serves as a benchmark, allowing researchers to compare the experimental group to the control group to see what sort of impact changes to the independent variable produced.  

Because participants have been randomly assigned to either the control group or the experimental group, it can be assumed that the groups are comparable.

Any differences between the two groups are, therefore, the result of the manipulations of the independent variable. The experimenters carry out the exact same procedures with both groups with the exception of the manipulation of the independent variable in the experimental group.

There are a number of different types of control groups that might be utilized in psychology research. Some of these include:

• Positive control groups : In this case, researchers already know that a treatment is effective but want to learn more about the impact of variations of the treatment. In this case, the control group receives the treatment that is known to work, while the experimental group receives the variation so that researchers can learn more about how it performs and compares to the control.
• Negative control group : In this type of control group, the participants are not given a treatment. The experimental group can then be compared to the group that did not experience any change or results.
• Placebo control group : This type of control group receives a placebo treatment that they believe will have an effect. This control group allows researchers to examine the impact of the placebo effect and how the experimental treatment compared to the placebo treatment.
• Randomized control group : This type of control group involves using random selection to help ensure that the participants in the control group accurately reflect the demographics of the larger population.
• Natural control group : This type of control group is naturally selected, often by situational factors. For example, researchers might compare people who have experienced trauma due to war to people who have not experienced war. The people who have not experienced war-related trauma would be the control group.

Examples of Control Groups

Control groups can be used in a variety of situations. For example, imagine a study in which researchers example how distractions during an exam influence test results. The control group would take an exam in a setting with no distractions, while the experimental groups would be exposed to different distractions. The results of the exam would then be compared to see the effects that distractions had on test scores.

Experiments that look at the effects of medications on certain conditions are also examples of how a control group can be used in research. For example, researchers looking at the effectiveness of a new antidepressant might use a control group that receives a placebo and an experimental group that receives the new medication. At the end of the study, researchers would compare measures of depression for both groups to determine what impact the new medication had.

After the experiment is complete, researchers can then look at the test results and start making comparisons between the control group and the experimental group.

Uses for Control Groups

Researchers utilize control groups to conduct research in a range of different fields. Some common uses include:

• Psychology : Researchers utilize control groups to learn more about mental health, behaviors, and treatments.
• Medicine : Control groups can be used to learn more about certain health conditions, assess how well medications work to treat these conditions, and assess potential side effects that may result.
• Education : Educational researchers utilize control groups to learn more about how different curriculums, programs, or instructional methods impact student outcomes.
• Marketing : Researchers utilize control groups to learn more about how consumers respond to advertising and marketing efforts.

Malay S, Chung KC. The choice of controls for providing validity and evidence in clinical research . Plast Reconstr Surg. 2012 Oct;130(4):959-965. doi:10.1097/PRS.0b013e318262f4c8

National Cancer Institute. Control group.

Pithon MM. Importance of the control group in scientific research . Dental Press J Orthod. 2013;18(6):13-14. doi:10.1590/s2176-94512013000600003

Karlsson P, Bergmark A. Compared with what? An analysis of control-group types in Cochrane and Campbell reviews of psychosocial treatment efficacy with substance use disorders . Addiction . 2015;110(3):420-8. doi:10.1111/add.12799

Myers A, Hansen C. Experimental Psychology . Belmont, CA: Cengage Learning; 2012.

By Kendra Cherry, MSEd Kendra Cherry, MS, is a psychosocial rehabilitation specialist, psychology educator, and author of the "Everything Psychology Book."

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control group

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• Verywell Mind - What Is a Control Group?
• National Center for Biotechnology Information - PubMed Central - Control Group Design: Enhancing Rigor in Research of Mind-Body Therapies for Depression

control group , the standard to which comparisons are made in an experiment. Many experiments are designed to include a control group and one or more experimental groups; in fact, some scholars reserve the term experiment for study designs that include a control group. Ideally, the control group and the experimental groups are identical in every way except that the experimental groups are subjected to treatments or interventions believed to have an effect on the outcome of interest while the control group is not. Inclusion of a control group greatly strengthens researchers’ ability to draw conclusions from a study. Indeed, only in the presence of a control group can a researcher determine whether a treatment under investigation truly has a significant effect on an experimental group, and the possibility of making an erroneous conclusion is reduced. See also scientific method .

A typical use of a control group is in an experiment in which the effect of a treatment is unknown and comparisons between the control group and the experimental group are used to measure the effect of the treatment. For instance, in a pharmaceutical study to determine the effectiveness of a new drug on the treatment of migraines , the experimental group will be administered the new drug and the control group will be administered a placebo (a drug that is inert, or assumed to have no effect). Each group is then given the same questionnaire and asked to rate the effectiveness of the drug in relieving symptoms . If the new drug is effective, the experimental group is expected to have a significantly better response to it than the control group. Another possible design is to include several experimental groups, each of which is given a different dosage of the new drug, plus one control group. In this design, the analyst will compare results from each of the experimental groups to the control group. This type of experiment allows the researcher to determine not only if the drug is effective but also the effectiveness of different dosages. In the absence of a control group, the researcher’s ability to draw conclusions about the new drug is greatly weakened, due to the placebo effect and other threats to validity. Comparisons between the experimental groups with different dosages can be made without including a control group, but there is no way to know if any of the dosages of the new drug are more or less effective than the placebo.

It is important that every aspect of the experimental environment be as alike as possible for all subjects in the experiment. If conditions are different for the experimental and control groups, it is impossible to know whether differences between groups are actually due to the difference in treatments or to the difference in environment. For example, in the new migraine drug study, it would be a poor study design to administer the questionnaire to the experimental group in a hospital setting while asking the control group to complete it at home. Such a study could lead to a misleading conclusion, because differences in responses between the experimental and control groups could have been due to the effect of the drug or could have been due to the conditions under which the data were collected. For instance, perhaps the experimental group received better instructions or was more motivated by being in the hospital setting to give accurate responses than the control group.

In non-laboratory and nonclinical experiments, such as field experiments in ecology or economics , even well-designed experiments are subject to numerous and complex variables that cannot always be managed across the control group and experimental groups. Randomization, in which individuals or groups of individuals are randomly assigned to the treatment and control groups, is an important tool to eliminate selection bias and can aid in disentangling the effects of the experimental treatment from other confounding factors. Appropriate sample sizes are also important.

A control group study can be managed in two different ways. In a single-blind study, the researcher will know whether a particular subject is in the control group, but the subject will not know. In a double-blind study , neither the subject nor the researcher will know which treatment the subject is receiving. In many cases, a double-blind study is preferable to a single-blind study, since the researcher cannot inadvertently affect the results or their interpretation by treating a control subject differently from an experimental subject.

The Importance of Control Group Analysis in Scientific Research

Explore the crucial role of control groups in scientific research, enhancing validity and ensuring accurate results.

Control groups are a fundamental component of scientific research, serving as a benchmark to measure the effects of experimental treatments. By comparing outcomes between the control group and the experimental group, researchers can attribute changes in the dependent variable to the independent variable, thus ensuring the internal validity of the study. Without control groups, it becomes challenging to draw accurate conclusions and determine the true efficacy of a treatment or intervention.

Key Takeaways

• Control groups are essential for ensuring the internal validity of scientific research.
• They serve as a baseline to compare the effects of the independent variable on the dependent variable.
• Control groups help in avoiding research biases and confounding variables.
• Different types of control groups, such as positive, negative, and placebo, are used depending on the study design.
• Properly designed control groups enhance the reproducibility and reliability of research findings.

The Role of Control Groups in Ensuring Internal Validity

Control groups are critical to the scientific method as they help ensure the internal validity of a study. Without a control group, it’s harder to be certain that the outcome was caused by the experimental treatment and not by other variables. This is essential for drawing accurate conclusions and avoiding research bias.

Defining Internal Validity

Internal validity refers to the extent to which a study can demonstrate a causal relationship between the treatment and the observed outcome. It ensures that the results are due to the independent variable and not other factors. Control groups play a pivotal role in maintaining this validity by providing a baseline for comparison.

How Control Groups Enhance Validity

Control groups help account for the placebo effect, where participants’ beliefs about the treatment can influence their behavior or responses. By comparing the treatment group to the control group, researchers can isolate the effect of the treatment itself. This increases the internal validity of the results and the confidence we can have in the conclusions.

Examples of Validity in Research

Consider a study testing a new medication for ADHD. One group receives the new medication, while the other group receives a placebo. The placebo group serves as the control group, allowing researchers to determine if changes in the treatment group are due to the medication or other variables. This method is crucial for the future of measurement: triangulating MTA, MMM, and incrementality testing . Triangulation offers a holistic view of marketing effectiveness, optimizing resource allocation for brands.

Types of Control Groups in Scientific Research

Control groups are critical to the scientific method as they help ensure the internal validity of a study. Using a control group means that any change in the dependent variable can be attributed to the independent variable. This helps avoid extraneous variables or confounding variables from impacting your work, as well as a few types of research bias, like omitted variable bias.

Positive Control Groups

Positive control groups are used to ensure that the experimental setup is capable of producing results. For example, if you are testing a new drug, a positive control group might receive a treatment that is already known to produce a certain effect. This helps to confirm that the experimental conditions are working as expected.

Negative Control Groups

Negative control groups are used to ensure that no confounding variable has affected the results. In a drug trial, a negative control group might receive a placebo, which is a treatment that has no therapeutic effect. This helps to show that any changes in the experimental group are due to the treatment itself and not some other factor.

Placebo Control Groups

Placebo control groups are a specific type of negative control group used in clinical trials. Participants in the placebo group receive a treatment that looks identical to the experimental treatment but has no active ingredient. This helps to account for the placebo effect, where participants experience changes simply because they believe they are receiving a treatment.

In clinical trials, the use of placebo control groups is essential for determining the true efficacy of a new treatment. Without this control, it would be difficult to distinguish between the actual effects of the treatment and the psychological impact of believing one is being treated.

Designing Experiments with Control Groups

Designing experiments with control groups is a critical aspect of scientific research. It ensures that the results are reliable and can be attributed to the variables being tested. Here, we will discuss the key elements involved in this process.

Random Assignment

Random assignment is the process of assigning participants to different groups using randomization. This method ensures that each participant has an equal chance of being placed in any group, thereby eliminating selection bias. Random assignment is crucial for maintaining the internal validity of an experiment. For example, in a marketing experiment design, participants might be randomly assigned to either a control group or an experimental group to test the effectiveness of a new advertising strategy.

Blinding and Control Groups

Blinding is a technique used to prevent bias in research. In a single-blind experiment, the participants do not know whether they are in the control group or the experimental group. In a double-blind experiment, neither the participants nor the researchers know who is in which group. This method is particularly useful in medical research, where the placebo effect can influence results. For instance, in a study testing a new drug, blinding ensures that neither the patients nor the doctors know who is receiving the actual medication and who is receiving a placebo.

Maintaining Consistency

Maintaining consistency across all groups in an experiment is essential for obtaining valid results. This means that all conditions, except for the variable being tested, should be kept the same for both the control and experimental groups. For example, in geo experiments, researchers might implement geo-based incrementality testing to measure the real impact of a marketing campaign. By keeping all other variables constant, they can accurately determine the effectiveness of the campaign.

In any well-designed experiment, the control group serves as a benchmark, allowing researchers to measure the true effect of the independent variable. This is especially important in fields like marketing budget planning, where understanding the actual impact of different strategies can lead to more informed decisions.

Challenges and Limitations of Control Group Analysis

Ethical considerations.

When conducting Control Group Analysis , researchers must navigate various ethical dilemmas. For instance, withholding a potentially beneficial treatment from the control group can raise ethical concerns. Balancing the need for rigorous scientific methods with ethical responsibilities is crucial. Researchers often use alternative methodologies to address these challenges, such as crossover designs where participants receive both the treatment and control conditions at different times.

Practical Limitations

Implementing control groups can be resource-intensive. Researchers may face constraints related to time, budget, and participant availability. These limitations can impact the scope and scale of the study. Additionally, maintaining consistency across control and treatment groups can be challenging, especially in long-term studies. Practical solutions include using automated systems for data collection and employing robust randomization techniques.

Addressing Confounding Variables

Confounding variables can significantly impact the validity of a study. These are variables that the researcher failed to control or eliminate, which can cause a false association between the treatment and the outcome. To mitigate this, researchers can use techniques like stratified randomization and matching. Identifying and addressing confounding variables is essential for enhancing the reliability of the results.

Ensuring the internal validity of your research often hinges on how well you manage these challenges. By addressing ethical considerations, practical limitations, and confounding variables, you can significantly improve the robustness of your Control Group Analysis.

Case Studies Highlighting the Importance of Control Groups

Medical research examples.

In medical research, control groups are indispensable for determining the effectiveness of new treatments . For instance, in a clinical trial for a new drug, one group receives the drug while the control group receives a placebo. This setup helps in measuring the Incremental Lift in patient recovery rates attributable to the drug, rather than other factors.

Control groups in medical research ensure that the observed effects are due to the treatment and not external variables.

Psychological Studies

Psychological studies often use control groups to understand the impact of various interventions. For example, a study on the effects of cognitive-behavioral therapy (CBT) for depression might have one group undergo CBT while the control group receives no treatment. This helps in isolating the Incremental Contribution of CBT to improvements in mental health.

Social Science Research

In social science research, control groups help in understanding societal trends and behaviors. For example, a study on the impact of educational programs on student performance might have a control group that does not participate in the program. This allows researchers to measure the Conversion Lift in academic performance due to the educational intervention.

Without control groups, it would be challenging to attribute changes in the dependent variable to the independent variable accurately.

Measuring the Effectiveness of Control Groups

Baseline comparisons.

An important factor when measuring the effectiveness of a control group is the uniformity of samples. Ensuring the control group is both random and representative of the entire population will lead to more dependable results. The control group serves as a baseline , enabling researchers to see what impact changes to the independent variable produce and strengthening researchers’ ability to draw conclusions from a study.

Without the presence of a control group, a researcher cannot determine whether a particular treatment truly has an effect on an experimental group.

Statistical Methods

A chi-squared statistic can reveal differences between the observed results and the results you would expect if there was no relationship in the data. For example, the expectation of variations to have zero impact on conversion rate can be tested using this method. Here are some steps to execute this analysis:

• Define the null hypothesis that there is no difference between the control and test groups.
• Collect data from both groups.
• Calculate the chi-squared statistic.
• Compare the calculated value with the critical value from the chi-squared distribution table.
• Draw conclusions based on the comparison.

Interpreting Results

When interpreting results, it is crucial to consider the size of the control group. The tradeoff between confidence levels in the results and the opportunity cost of implementing a more successful variation should not be taken lightly. For instance, if the experiment is run on a population size of only 100 participants, a 5% control group would be only 5 individuals, which would certainly diminish the significance of the results. Therefore, maintaining an adequately sized control group is essential for reliable conclusions.

The Impact of Control Groups on Research Outcomes

Drawing accurate conclusions.

Control groups are essential for drawing accurate conclusions in scientific research. By comparing the treatment group to the control group, researchers can isolate the effect of the independent variable. This helps in determining whether the observed changes are due to the treatment or other external factors. For instance, in medical research , a control group receiving a placebo can help identify the true efficacy of a new drug.

Avoiding Research Bias

Control groups play a crucial role in avoiding research bias. They help mitigate the impact of confounding variables and ensure that the results are not skewed by external influences. This is particularly important in psychological studies , where participant expectations can influence outcomes. By using control groups, researchers can ensure that any observed effects are due to the treatment itself and not other factors.

Enhancing Reproducibility

The use of control groups enhances the reproducibility of research findings. When other researchers can replicate the study and achieve similar results, it strengthens the validity of the original findings. This is vital for the advancement of scientific knowledge. For example, in social science research , control groups help in verifying the impact of interventions across different populations and settings.

Control groups are the backbone of rigorous scientific research, ensuring that findings are both valid and reliable.

• isolate the effect
• medical research
• psychological studies
• social science research

In conclusion, control group analysis is indispensable in scientific research. Control groups serve as a baseline, allowing researchers to attribute changes in the dependent variable directly to the independent variable, thereby ensuring the internal validity of the study. Without control groups, it becomes challenging to determine whether observed changes are due to the treatment or other extraneous variables. By providing a clear comparison, control groups enhance the reliability and credibility of research findings, making them a cornerstone of the scientific method. Therefore, the inclusion of control groups in experimental design is not just beneficial but essential for drawing accurate and meaningful conclusions.

Frequently Asked Questions

What is a control group in scientific research.

A control group is a group of participants in an experiment who do not receive the experimental treatment. They serve as a baseline to compare the results of the experimental group against.

Why are control groups important in scientific research?

Control groups help ensure the internal validity of research by providing a baseline. This allows researchers to determine if changes in the dependent variable are due to the independent variable or other factors.

What are the different types of control groups?

There are several types of control groups, including positive control groups, negative control groups, and placebo control groups. Each type serves a different purpose in validating the results of an experiment.

How do control groups enhance the validity of an experiment?

Control groups enhance validity by isolating the effect of the independent variable. This helps to avoid confounding variables and research biases, ensuring that the observed effects are due to the treatment.

What are some challenges associated with using control groups?

Challenges include ethical considerations, practical limitations, and the need to address confounding variables. Researchers must design their studies carefully to mitigate these issues.

Can you provide an example of a control group in research?

In medical research, a control group might receive a placebo while the experimental group receives the actual medication. This allows researchers to determine if the medication has a real effect compared to no treatment.

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Statistics By Jim

Making statistics intuitive

Control Group in an Experiment

By Jim Frost 3 Comments

A control group in an experiment does not receive the treatment. Instead, it serves as a comparison group for the treatments. Researchers compare the results of a treatment group to the control group to determine the effect size, also known as the treatment effect.

Imagine that a treatment group receives a vaccine and it has an infection rate of 10%. By itself, you don’t know if that’s an improvement. However, if you also have an unvaccinated control group with an infection rate of 20%, you know the vaccine improved the outcome by 10 percentage points.

By serving as a basis for comparison, the control group reveals the treatment’s effect.

Related post : Effect Sizes in Statistics

Using Control Groups in Experiments

Most experiments include a control group and at least one treatment group. In an ideal experiment, the subjects in all groups start with the same overall characteristics except that those in the treatment groups receive a treatment. When the groups are otherwise equivalent before treatment begins, you can attribute differences after the experiment to the treatments.

Randomized controlled trials (RCTs) assign subjects to the treatment and control groups randomly. This process helps ensure the groups are comparable when treatment begins. Consequently, treatment effects are the most likely cause for differences between groups at the end of the study. Statisticians consider RCTs to be the gold standard. To learn more about this process, read my post, Random Assignment in Experiments .

Observational studies either can’t use randomized groups or don’t use them because they’re too costly or problematic. In these studies, the characteristics of the control group might be different from the treatment groups at the start of the study, making it difficult to estimate the treatment effect accurately at the end. Case-Control studies are a specific type of observational study that uses a control group.

For these types of studies, analytical methods and design choices, such as regression analysis and matching, can help statistically mitigate confounding variables. Matching involves selecting participants with similar characteristics. For each participant in the treatment group, the researchers find a subject with comparable traits to include in the control group. To learn more about this type of study and matching, read my post, Observational Studies Explained .

Control groups are key way to increase the internal validity of an experiment. To learn more, read my post about internal and external validity .

Randomized versus non-randomized control groups are just several of the different types you can have. We’ll look at more kinds later!

Related posts : When to Use Regression Analysis

Example of a Control Group

Suppose we want to determine whether regular vitamin consumption affects the risk of dying. Our experiment has the following two experimental groups:

• Control group : Does not consume vitamin supplements
• Treatment group : Regularly consumes vitamin supplements.

In this experiment, we randomly assign subjects to the two groups. Because we use random assignment, the two groups start with similar characteristics, including healthy habits, physical attributes, medical conditions, and other factors affecting the outcome. The intentional introduction of vitamin supplements in the treatment group is the only systematic difference between the groups.

After the experiment is complete, we compare the death risk between the treatment and control groups. Because the groups started roughly equal, we can reasonably attribute differences in death risk at the end of the study to vitamin consumption. By having the control group as the basis of comparison, the effect of vitamin consumption becomes clear!

Types of Control Groups

Researchers can use different types of control groups in their experiments. Earlier, you learned about the random versus non-random kinds, but there are other variations. You can use various types depending on your research goals, constraints, and ethical issues, among other things.

Negative Control Group

The group introduces a condition that the researchers expect won’t have an effect. This group typically receives no treatment. These experiments compare the effectiveness of the experimental treatment to no treatment. For example, in a vaccine study, a negative control group does not get the vaccine.

Positive Control Group

Positive control groups typically receive a standard treatment that science has already proven effective. These groups serve as a benchmark for the performance of a conventional treatment. In this vein, experiments with positive control groups compare the effectiveness of a new treatment to a standard one.

For example, an old blood pressure medicine can be the treatment in a positive control group, while the treatment group receives the new, experimental blood pressure medicine. The researchers want to determine whether the new treatment is better than the previous treatment.

In these studies, subjects can still take the standard medication for their condition, a potentially critical ethics issue.

Placebo Control Group

Placebo control groups introduce a treatment lookalike that will not affect the outcome. Standard examples of placebos are sugar pills and saline solution injections instead of genuine medicine. The key is that the placebo looks like the actual treatment. Researchers use this approach when the recipients’ belief that they’re receiving the treatment might influence their outcomes. By using placebos, the experiment controls for these psychological benefits. The researchers want to determine whether the treatment performs better than the placebo effect.

Learn more about the Placebo Effect .

Blinded Control Groups

If the subject’s awareness of their group assignment might affect their outcomes, the researchers can use a blinded experimental design that does not tell participants their group membership. Typically, blinded control groups will receive placebos, as described above. In a double-blinded control group, both subjects and researchers don’t know group assignments.

Waitlist Control Group

When there is a waitlist to receive a new treatment, those on the waitlist can serve as a control group until they receive treatment. This type of design avoids ethical concerns about withholding a better treatment until the study finishes. This design can be a variation of a positive control group because the subjects might be using conventional medicines while on the waitlist.

Historical Control Group

When historical data for a comparison group exists, it can serve as a control group for an experiment. The group doesn’t exist in the study, but the researchers compare the treatment group to the existing data. For example, the researchers might have infection rate data for unvaccinated individuals to compare to the infection rate among the vaccinated participants in their study. This approach allows everyone in the experiment to receive the new treatment. However, differences in place, time, and other circumstances can reduce the value of these comparisons. In other words, other factors might account for the apparent effects.

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Reader Interactions

December 19, 2021 at 9:17 am

Thank you very much Jim for your quick and comprehensive feedback. Extremely helpful!! Regards, Arthur

December 17, 2021 at 4:46 pm

Thank you very much Jim, very interesting article.

Can I select a control group at the end of intervention/experiment? Currently I am managing a project in rural Cambodia in five villages, however I did not select any comparison/control site at the beginning. Since I know there are other villages which have not been exposed to any type of intervention, can i select them as a control site during my end-line data collection or it will not be a legitimate control? Thank you very much, Arthur

December 18, 2021 at 1:51 am

You might be able to use that approach, but it’s not ideal. The ideal is to have control groups defined at the beginning of the study. You can use the untreated villages as a type of historical control groups that I talk about in this article. Or, if they’re awaiting to receive the intervention, it might be akin to a waitlist control group.

If you go that route, you’ll need to consider whether there was some systematic reason why these villages have not received any intervention. For example, are the villages in question more remote? And, if there is a systematic reason, would that affect your outcome variable? More generally, are they systematically different? How well do the untreated villages represent your target population?

If you had selected control villages at the beginning, you’d have been better able to ensure there weren’t any systematic differences between the villages receiving interventions and those that didn’t.

If the villages that didn’t receive any interventions are systematically different, you’ll need to incorporate that into your interpretation of the results. Are they different in ways that affect the outcomes you’re measuring? Can those differences account for the difference in outcomes between the treated and untreated villages? Hopefully, you’d be able to measure those differences between untreated/treated villages.

So, yes, you can use that approach. It’s not perfect and there will potentially be more things for you to consider and factor into your conclusions. Despite these drawbacks, it’s possible that using a pseudo control group like that is better than not doing that because at least you can make comparisons to something. Otherwise, you won’t know whether the outcomes in the intervention villages represent an improvement! Just be aware of the extra considerations!

Best of luck with your research!

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Understanding Control Groups for Research

Introduction

What are control groups in research, examples of control groups in research, control group vs. experimental group, types of control groups, control groups in non-experimental research.

A control group is typically thought of as the baseline in an experiment. In an experiment, clinical trial, or other sort of controlled study, there are at least two groups whose results are compared against each other.

The experimental group receives some sort of treatment, and their results are compared against those of the control group, which is not given the treatment. This is important to determine whether there is an identifiable causal relationship between the treatment and the resulting effects.

As intuitive as this may sound, there is an entire methodology that is useful to understanding the role of the control group in experimental research and as part of a broader concept in research. This article will examine the particulars of that methodology so you can design your research more rigorously .

Suppose that a friend or colleague of yours has a headache. You give them some over-the-counter medicine to relieve some of the pain. Shortly after they take the medicine, the pain is gone and they feel better. In casual settings, we can assume that it must be the medicine that was the cause of their headache going away.

In scientific research, however, we don't really know if the medicine made a difference or if the headache would have gone away on its own. Maybe in the time it took for the headache to go away, they ate or drank something that might have had an effect. Perhaps they had a quick nap that helped relieve the tension from the headache. Without rigorously exploring this phenomenon , any number of confounding factors exist that can make us question the actual efficacy of any particular treatment.

Experimental research relies on observing differences between the two groups by "controlling" the independent variable , or in the case of our example above, the medicine that is given or not given depending on the group. The dependent variable in this case is the change in how the person suffering the headache feels, and the difference between taking and not taking the medicine is evidence (or lack thereof) that the treatment is effective.

The catch is that, between the control group and other groups (typically called experimental groups), it's important to ensure that all other factors are the same or at least as similar as possible. Things such as age, fitness level, and even occupation can affect the likelihood someone has a headache and whether a certain medication is effective.

Faced with this dynamic, researchers try to make sure that participants in their control group and experimental group are as similar as possible to each other, with the only difference being the treatment they receive.

Experimental research is often associated with scientists in lab coats holding beakers containing liquids with funny colors. Clinical trials that deal with medical treatments rely primarily, if not exclusively, on experimental research designs involving comparisons between control and experimental groups.

However, many studies in the social sciences also employ some sort of experimental design which calls for the use of control groups. This type of research is useful when researchers are trying to confirm or challenge an existing notion or measure the difference in effects.

Workplace efficiency research

How might a company know if an employee training program is effective? They may decide to pilot the program to a small group of their employees before they implement the training to their entire workforce.

If they adopt an experimental design, they could compare results between an experimental group of workers who participate in the training program against a control group who continues as per usual without any additional training.

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Mental health research

Music certainly has profound effects on psychology, but what kind of music would be most effective for concentration? Here, a researcher might be interested in having participants in a control group perform a series of tasks in an environment with no background music, and participants in multiple experimental groups perform those same tasks with background music of different genres. The subsequent analysis could determine how well people perform with classical music, jazz music, or no music at all in the background.

Educational research

Suppose that you want to improve reading ability among elementary school students, and there is research on a particular teaching method that is associated with facilitating reading comprehension. How do you measure the effects of that teaching method?

A study could be conducted on two groups of otherwise equally proficient students to measure the difference in test scores. The teacher delivers the same instruction to the control group as they have to previous students, but they teach the experimental group using the new technique. A reading test after a certain amount of instruction could determine the extent of effectiveness of the new teaching method.

As you can see from the three examples above, experimental groups are the counterbalance to control groups. A control group offers an essential point of comparison. For an experimental study to be considered credible, it must establish a baseline against which novel research is conducted.

Researchers can determine the makeup of their experimental and control groups from their literature review . Remember that the objective of a review is to establish what is known about the object of inquiry and what is not known. Where experimental groups explore the unknown aspects of scientific knowledge, a control group is a sort of simulation of what would happen if the treatment or intervention was not administered. As a result, it will benefit researchers to have a foundational knowledge of the existing research to create a credible control group against which experimental results are compared, especially in terms of remaining sensitive to relevant participant characteristics that could confound the effects of your treatment or intervention so that you can appropriately distribute participants between the experimental and control groups.

There are multiple control groups to consider depending on the study you are looking to conduct. All of them are variations of the basic control group used to establish a baseline for experimental conditions.

No-treatment control group

This kind of control group is common when trying to establish the effects of an experimental treatment against the absence of treatment. This is arguably the most straightforward approach to an experimental design as it aims to directly demonstrate how a certain change in conditions produces an effect.

Placebo control group

In this case, the control group receives some sort of treatment under the exact same procedures as those in the experimental group. The only difference in this case is that the treatment in the placebo control group has already been judged to be ineffective, except that the research participants don't know that it is ineffective.

Placebo control groups (or negative control groups) are useful for allowing researchers to account for any psychological or affective factors that might impact the outcomes. The negative control group exists to explicitly eliminate factors other than changes in the independent variable conditions as causes of the effects experienced in the experimental group.

Positive control group

Contrasted with a no-treatment control group, a positive control group employs a treatment against which the treatment in the experimental group is compared. However, unlike in a placebo group, participants in a positive control group receive treatment that is known to have an effect.

If we were to use our first example of headache medicine, a researcher could compare results between medication that is commonly known as effective against the newer medication that the researcher thinks is more effective. Positive control groups are useful for validating experimental results when compared against familiar results.

Historical control group

Rather than study participants in control group conditions, researchers may employ existing data to create historical control groups. This form of control group is useful for examining changing conditions over time, particularly when incorporating past conditions that can't be replicated in the analysis.

Qualitative research more often relies on non-experimental research such as observations and interviews to examine phenomena in their natural environments. This sort of research is more suited for inductive and exploratory inquiries, not confirmatory studies meant to test or measure a phenomenon.

That said, the broader concept of a control group is still present in observational and interview research in the form of a comparison group. Comparison groups are used in qualitative research designs to show differences between phenomena, with the exception being that there is no baseline against which data is analyzed.

Comparison groups are useful when an experimental environment cannot produce results that would be applicable to real-world conditions. Research inquiries examining the social world face challenges of having too many variables to control, making observations and interviews across comparable groups more appropriate for data collection than clinical or sterile environments.

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Control Group: The Key Elements In Experimental Research

Understand the design and interpretation of control group in research experiments for powerful conclusions

The control group constitutes a baseline for comparison, enabling researchers to assess the true effects of independent variables. Researchers can effectively assess the impact of independent variables and discern causation from correlation, by comparing the results of experimental groups to those of control groups. This article will highlight the significance and implementation of control groups in research experiments, and explain their role in ensuring scientific methodology and reliable findings. We will explore the fundamental principles of control groups, examine their types, and discuss their importance in minimizing biases and confounding factors.

What Is A Control Group?

A control group is a fundamental component of scientific experiments designed to compare and evaluate the effects of an intervention or treatment. It serves as a baseline against which the experimental group is measured. The control group consists of individuals or subjects who do not receive the experimental treatment but are otherwise subjected to the same conditions and procedures as the experimental group. Working with a control group, researchers can assess the specific impact of the intervention by comparing the outcomes between the experimental and control groups.

Related article: The Role Of Experimental Groups In Research

The Role Of A Control Group In Scientific Experiments

A control group plays a crucial role in scientific experiments as it enables researchers to establish a valid cause-and-effect relationship between the experimental treatment and the observed outcomes. By comparing the experimental group’s results with those of the control group, researchers can determine whether any observed effects are due to the treatment or other factors. The control group serves as a standard for comparison, helping to isolate the specific influence of the intervention being tested. It provides a baseline against which experimental group outcomes can be evaluated and allows researchers to draw accurate conclusions about the treatment’s efficacy or the impact of other variables being studied.

Why Is A Control Group Necessary?

Including a control group in scientific experiments is essential for ensuring the reliability and validity of the findings. Without a control group, it becomes challenging to determine whether any observed changes or effects are truly attributable to the intervention or simply a result of chance or other factors. The control group allows researchers to differentiate between the effects of the experimental treatment and background noise or confounding variables because it provides a reference point. A well-designed control group is crucial for generating reliable and meaningful results, intensifying the scientific rigor of the study, and supporting evidence-based decision-making in various fields of research.

Types Of Control Groups

In scientific experiments, different types of control groups are used to ensure accurate and meaningful results. These control groups help researchers compare the effects of an intervention or treatment against a reference point. Four common types of control groups are negative controls, positive controls, placebo controls, and randomized control groups.

Negative Controls

Negative controls are an integral part of scientific experiments, serving as a reference to establish the absence of a specific effect. In these control groups, no treatment is administered, allowing researchers to compare the outcomes with the experimental group. Researchers can identify and account for confounding variables and background effects that may influence the results when they include negative control groups. This ensures the specificity of the treatment and enhances the validity of the study. Negative controls can take various forms, such as placebos or control groups receiving no treatment, depending on the research question.

Positive controls

Positive controls are references to validate the reliability and sensitivity of the experimental setup. In these control groups, a known treatment or condition is applied to generate an expected response or outcome. By including positive controls, researchers can assess whether the experimental conditions and methodology are capable of detecting the desired effect. Positive controls act as a benchmark, providing evidence that the experimental system is functioning properly and capable of producing the anticipated results. This helps researchers ensure the validity and accuracy of their findings by confirming that the experimental conditions are conducive to detecting the intended response.

Placebo controls

Placebo controls play a significant role in medical and clinical research by providing a baseline for comparison and evaluating the effectiveness of a new treatment or intervention. In a placebo control group, participants receive an inactive substance or sham procedure that is indistinguishable from the active treatment being tested. The purpose of the placebo control is to assess the specific effects of the treatment by comparing it to the effects observed in the placebo group. By administering a placebo, researchers can account for the psychological and physiological responses that may occur simply due to the participants’ belief in receiving treatment. This helps determine the true efficacy of the active treatment, as any observed improvements in the treatment group can be attributed to the treatment itself, beyond the placebo effect. Placebo controls are essential in clinical trials and other studies to minimize bias, establish the true therapeutic benefits of treatment, and ensure the reliability of the results.

Randomized Control Group

Randomized control groups are an essential component of research studies as they introduce unpredictability to control factors. By randomly assigning participants to either the control or treatment group, researchers ensure that the variables not specifically tested are evenly distributed. This randomization helps eliminate bias and allows for accurate analysis of the independent variable. By using randomized control groups, researchers can draw reliable conclusions about the impact of the variables being studied. 

Quasi-Experimental Designs And Their Role In Social Policy Studies

Quasi-experimental designs in social policy studies often utilize control groups to assess the impact of interventions or policies on a target population. While these designs do not involve random assignment of participants to groups, they still incorporate a control group to establish a baseline for comparison. The control group consists of individuals who do not receive the intervention or policy being studied, allowing researchers to evaluate the effects of the intervention by comparing outcomes between the treatment group and the control group. This helps control for confounding variables and provides insights into a causal relationship between the intervention and the observed outcomes. 

Implementing Control Groups In Experimental Design And Analysis

Control groups serve as a reference point against which the effects of experimental interventions can be measured. They provide a baseline to compare with the treatment group, allowing researchers to determine the true impact of the variables under investigation. This approach helps establish causal relationships and increases the internal validity of the research. 

Randomized Controlled Experiments (RCTs) For Public Policy Studies

Randomized controlled experiments are widely used in public policy studies. RCTs involve randomly assigning participants to either a treatment group or a control group. The treatment group receives the intervention or policy being tested, while the control group does not. RCTs help ensure that any observed differences between the groups are not due to pre-existing factors, increasing the reliability of the study’s findings. RCTs are particularly valuable in evaluating the impact of public policies and interventions on a large scale.

Non-Experimental Research Vs. Actual Experimentation

When determining the baseline for comparison in research, researchers must consider whether to use non-experimental research or actual experimentation. Non-experimental research involves observing and analyzing existing data without manipulating any variables. This approach is helpful in situations where it is not feasible or ethical to conduct an experiment. On the other hand, actual experimentation involves actively manipulating variables and comparing groups with and without the intervention. While actual experimentation provides stronger causal evidence, non-experimental research can still provide valuable insights when experiments are not possible.

Identifying Confounding Variables And Factors

Confounding variables and factors are extraneous variables that can influence the relationship between the independent and dependent variables in a study. Identifying and controlling for confounding variables is crucial to ensure accurate and valid results. Researchers employ various techniques to address confounding variables, such as random assignment of participants to groups, matching participants based on relevant characteristics, or statistical techniques like regression analysis. By accounting for confounding variables, researchers can strengthen the internal validity of their studies and draw more accurate conclusions about the relationship between variables.

The Vital Role Of The Control Group In Scientific Methodology And Analysis

In experimental studies, the control group serves as a standard against which the effects of a particular intervention or treatment are measured. By keeping all variables constant except for the one being studied, researchers can isolate the true impact of the intervention. This helps to establish causality and determine whether the observed effects are indeed due to the intervention or simply a result of other factors.

In addition to experimental studies, control groups are also essential in observational and epidemiological research. They help researchers account for potential biases and confounding factors when analyzing the relationship between variables. By comparing a group exposed to a certain risk factor or condition with a similar group that is not exposed, researchers can better understand the true impact of the risk factor or condition on the outcome of interest.

Overall, the control group serves as a guide in scientific methodology and analysis. It allows researchers to draw valid and reliable conclusions, enhance the internal validity of their studies, and provide more robust evidence for decision-making in various fields, including medicine, psychology, biology, and social sciences.

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Controlled Experiment

Saul McLeod, PhD

Editor-in-Chief for Simply Psychology

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Saul McLeod, PhD., is a qualified psychology teacher with over 18 years of experience in further and higher education. He has been published in peer-reviewed journals, including the Journal of Clinical Psychology.

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This is when a hypothesis is scientifically tested.

In a controlled experiment, an independent variable (the cause) is systematically manipulated, and the dependent variable (the effect) is measured; any extraneous variables are controlled.

The researcher can operationalize (i.e., define) the studied variables so they can be objectively measured. The quantitative data can be analyzed to see if there is a difference between the experimental and control groups.

What is the control group?

In experiments scientists compare a control group and an experimental group that are identical in all respects, except for one difference – experimental manipulation.

Unlike the experimental group, the control group is not exposed to the independent variable under investigation and so provides a baseline against which any changes in the experimental group can be compared.

Since experimental manipulation is the only difference between the experimental and control groups, we can be sure that any differences between the two are due to experimental manipulation rather than chance.

Randomly allocating participants to independent variable groups means that all participants should have an equal chance of participating in each condition.

The principle of random allocation is to avoid bias in how the experiment is carried out and limit the effects of participant variables.

What are extraneous variables?

The researcher wants to ensure that the manipulation of the independent variable has changed the changes in the dependent variable.

Hence, all the other variables that could affect the dependent variable to change must be controlled. These other variables are called extraneous or confounding variables.

Extraneous variables should be controlled were possible, as they might be important enough to provide alternative explanations for the effects.

In practice, it would be difficult to control all the variables in a child’s educational achievement. For example, it would be difficult to control variables that have happened in the past.

A researcher can only control the current environment of participants, such as time of day and noise levels.

Why conduct controlled experiments?

Scientists use controlled experiments because they allow for precise control of extraneous and independent variables. This allows a cause-and-effect relationship to be established.

Controlled experiments also follow a standardized step-by-step procedure. This makes it easy for another researcher to replicate the study.

Key Terminology

Experimental group.

The group being treated or otherwise manipulated for the sake of the experiment.

Control Group

They receive no treatment and are used as a comparison group.

Ecological validity

The degree to which an investigation represents real-life experiences.

Experimenter effects

These are the ways that the experimenter can accidentally influence the participant through their appearance or behavior.

Demand characteristics

The clues in an experiment lead the participants to think they know what the researcher is looking for (e.g., the experimenter’s body language).

Independent variable (IV)

The variable the experimenter manipulates (i.e., changes) – is assumed to have a direct effect on the dependent variable.

Dependent variable (DV)

Variable the experimenter measures. This is the outcome (i.e., the result) of a study.

Extraneous variables (EV)

All variables that are not independent variables but could affect the results (DV) of the experiment. Extraneous variables should be controlled where possible.

Confounding variables

Variable(s) that have affected the results (DV), apart from the IV. A confounding variable could be an extraneous variable that has not been controlled.

Random Allocation

Randomly allocating participants to independent variable conditions means that all participants should have an equal chance of participating in each condition.

Order effects

Changes in participants’ performance due to their repeating the same or similar test more than once. Examples of order effects include:

(i) practice effect: an improvement in performance on a task due to repetition, for example, because of familiarity with the task;

(ii) fatigue effect: a decrease in performance of a task due to repetition, for example, because of boredom or tiredness.

What is the control in an experiment?

In an experiment , the control is a standard or baseline group not exposed to the experimental treatment or manipulation. It serves as a comparison group to the experimental group, which does receive the treatment or manipulation.

The control group helps to account for other variables that might influence the outcome, allowing researchers to attribute differences in results more confidently to the experimental treatment.

Establishing a cause-and-effect relationship between the manipulated variable (independent variable) and the outcome (dependent variable) is critical in establishing a cause-and-effect relationship between the manipulated variable.

What is the purpose of controlling the environment when testing a hypothesis?

Controlling the environment when testing a hypothesis aims to eliminate or minimize the influence of extraneous variables. These variables other than the independent variable might affect the dependent variable, potentially confounding the results.

By controlling the environment, researchers can ensure that any observed changes in the dependent variable are likely due to the manipulation of the independent variable, not other factors.

This enhances the experiment’s validity, allowing for more accurate conclusions about cause-and-effect relationships.

It also improves the experiment’s replicability, meaning other researchers can repeat the experiment under the same conditions to verify the results.

Why are hypotheses important to controlled experiments?

Hypotheses are crucial to controlled experiments because they provide a clear focus and direction for the research. A hypothesis is a testable prediction about the relationship between variables.

It guides the design of the experiment, including what variables to manipulate (independent variables) and what outcomes to measure (dependent variables).

The experiment is then conducted to test the validity of the hypothesis. If the results align with the hypothesis, they provide evidence supporting it.

The hypothesis may be revised or rejected if the results do not align. Thus, hypotheses are central to the scientific method, driving the iterative inquiry, experimentation, and knowledge advancement process.

What is the experimental method?

The experimental method is a systematic approach in scientific research where an independent variable is manipulated to observe its effect on a dependent variable, under controlled conditions.

Home » experimental control important

What An Experimental Control Is And Why It’s So Important

Daniel Nelson

An experimental control is used in scientific experiments to minimize the effect of variables which are not the interest of the study. The control can be an object, population, or any other variable which a scientist would like to “control.”

You may have heard of experimental control, but what is it? Why is an experimental control important? The function of an experimental control is to hold constant the variables that an experimenter isn’t interested in measuring.

This helps scientists ensure that there have been no deviations in the environment of the experiment that could end up influencing the outcome of the experiment, besides the variable they are investigating. Let’s take a closer look at what this means.

You may have ended up here to understand why a control is important in an experiment. A control is important for an experiment because it allows the experiment to minimize the changes in all other variables except the one being tested.

To start with, it is important to define some terminology.

Terminology Of A Scientific Experiment

Randomization is important as it allows for more non-biased results in experiments. Random numbers generators are often used both in scientific studies as well as on 지노 사이트 to make outcomes fairer.

Scientists use the scientific method to ask questions and come to conclusions about the nature of the world. After making an observation about some sort of phenomena they would like to investigate, a scientist asks what the cause of that phenomena could be. The scientist creates a hypothesis, a proposed explanation that answers the question they asked. A hypothesis doesn’t need to be correct, it just has to be testable.

The hypothesis is a prediction about what will happen during the experiment, and if the hypothesis is correct then the results of the experiment should align with the scientist’s prediction. If the results of the experiment do not align with the hypothesis, then a good scientist will take this data into consideration and form a new hypothesis that can better explain the phenomenon in question.

Independent and Dependent Variables

In order to form an effective hypothesis and do meaningful research, the researcher must define the experiment’s independent and dependent variables . The independent variable is the variable which the experimenter either manipulates or controls in an experiment to test the effects of this manipulation on the dependent variable. A dependent variable is a variable being measured to see if the manipulation has any effect.

Photo: frolicsomepl via Pixabay, CC0

For instance, if a researcher wanted to see how temperature impacts the behavior of a certain gas, the temperature they adjust would be the independent variable and the behavior of the gas the dependent variable.

Control Groups and Experimental Groups

There will frequently be two groups under observation in an experiment, the experimental group, and the control group . The control group is used to establish a baseline that the behavior of the experimental group can be compared to. If two groups of people were receiving an experimental treatment for a medical condition, one would be given the actual treatment (the experimental group) and one would typically be given a placebo or sugar pill (the control group).

Without an experimental control group, it is difficult to determine the effects of the independent variable on the dependent variable in an experiment. This is because there can always be outside factors that are influencing the behavior of the experimental group. The function of a control group is to act as a point of comparison, by attempting to ensure that the variable under examination (the impact of the medicine) is the thing responsible for creating the results of an experiment. The control group is holding other possible variables constant, such as the act of seeing a doctor and taking a pill, so only the medicine itself is being tested.

Why Are Experimental Controls So Important?

Experimental controls allow scientists to eliminate varying amounts of uncertainty in their experiments. Whenever a researcher does an experiment and wants to ensure that only the variable they are interested in changing is changing, they need to utilize experimental controls.

Experimental controls have been dubbed “controls” precisely because they allow researchers to control the variables they think might have an impact on the results of the study. If a researcher believes that some outside variables could influence the results of their research, they’ll use a control group to try and hold that thing constant and measure any possible influence it has on the results. It is important to note that there may be many different controls for an experiment, and the more complex a phenomenon under investigation is, the more controls it is likely to have.

Not only do controls establish a baseline that the results of an experiment can be compared to, they also allow researchers to correct for possible errors. If something goes wrong in the experiment, a scientist can check on the controls of the experiment to see if the error had to do with the controls. If so, they can correct this next time the experiment is done.

A Practical Example

Let’s take a look at a concrete example of experimental control. If an experimenter wanted to determine how different soil types impacted the germination period of seeds , they could set up four different pots. Each pot would be filled with a different soil type, planted with seeds, then watered and exposed to sunlight. Measurements would be taken regarding how long it took for the seeds to sprout in the different soil types.

Photo: Kaz via Pixabay, CC0

A control for this experiment might be to fill more pots with just the different types of soil and no seeds or to set aside some seeds in a pot with no soil. The goal is to try and determine that it isn’t something else other than the soil, like the nature of the seeds themselves, the amount of sun they were exposed to, or how much water they are given, that affected how quickly the seeds sprouted. The more variables a researcher controlled for, the surer they could be that it was the type of soil having an impact on the germination period.

  Not All Experiments Are Controlled

“It doesn’t matter how beautiful your theory is, it doesn’t matter how smart you are. If it doesn’t agree with experiment, it’s wrong.” — Richard P. Feynman

While experimental controls are important , it is also important to remember that not all experiments are controlled. In the real world, there are going to be limitations on what variables a researcher can control for, and scientists often try to record as much data as they can during an experiment so they can compare factors and variables with one another to see if any variables they didn’t control for might have influenced the outcome. It’s still possible to draw useful data from experiments that don’t have controls, but it is much more difficult to draw meaningful conclusions based on uncontrolled data.

Though it is often impossible in the real world to control for every possible variable, experimental controls are an invaluable part of the scientific process and the more controls an experiment has the better off it is.

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Controlled Experiments | Methods & Examples of Control

Published on 19 April 2022 by Pritha Bhandari . Revised on 10 October 2022.

In experiments , researchers manipulate independent variables to test their effects on dependent variables. In a controlled experiment , all variables other than the independent variable are controlled or held constant so they don’t influence the dependent variable.

Controlling variables can involve:

• Holding variables at a constant or restricted level (e.g., keeping room temperature fixed)
• Measuring variables to statistically control for them in your analyses
• Balancing variables across your experiment through randomisation (e.g., using a random order of tasks)

Table of contents

Why does control matter in experiments, methods of control, problems with controlled experiments, frequently asked questions about controlled experiments.

Control in experiments is critical for internal validity , which allows you to establish a cause-and-effect relationship between variables.

• Your independent variable is the colour used in advertising.
• Your dependent variable is the price that participants are willing to pay for a standard fast food meal.

Extraneous variables are factors that you’re not interested in studying, but that can still influence the dependent variable. For strong internal validity, you need to remove their effects from your experiment.

• Design and description of the meal
• Study environment (e.g., temperature or lighting)
• Participant’s frequency of buying fast food
• Participant’s familiarity with the specific fast food brand
• Participant’s socioeconomic status

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You can control some variables by standardising your data collection procedures. All participants should be tested in the same environment with identical materials. Only the independent variable (e.g., advert colour) should be systematically changed between groups.

Other extraneous variables can be controlled through your sampling procedures . Ideally, you’ll select a sample that’s representative of your target population by using relevant inclusion and exclusion criteria (e.g., including participants from a specific income bracket, and not including participants with colour blindness).

By measuring extraneous participant variables (e.g., age or gender) that may affect your experimental results, you can also include them in later analyses.

After gathering your participants, you’ll need to place them into groups to test different independent variable treatments. The types of groups and method of assigning participants to groups will help you implement control in your experiment.

Control groups

Controlled experiments require control groups . Control groups allow you to test a comparable treatment, no treatment, or a fake treatment, and compare the outcome with your experimental treatment.

You can assess whether it’s your treatment specifically that caused the outcomes, or whether time or any other treatment might have resulted in the same effects.

• A control group that’s presented with red advertisements for a fast food meal
• An experimental group that’s presented with green advertisements for the same fast food meal

Random assignment

To avoid systematic differences between the participants in your control and treatment groups, you should use random assignment .

This helps ensure that any extraneous participant variables are evenly distributed, allowing for a valid comparison between groups .

Random assignment is a hallmark of a ‘true experiment’ – it differentiates true experiments from quasi-experiments .

Masking (blinding)

Masking in experiments means hiding condition assignment from participants or researchers – or, in a double-blind study , from both. It’s often used in clinical studies that test new treatments or drugs.

Sometimes, researchers may unintentionally encourage participants to behave in ways that support their hypotheses. In other cases, cues in the study environment may signal the goal of the experiment to participants and influence their responses.

Using masking means that participants don’t know whether they’re in the control group or the experimental group. This helps you control biases from participants or researchers that could influence your study results.

Although controlled experiments are the strongest way to test causal relationships, they also involve some challenges.

Difficult to control all variables

Especially in research with human participants, it’s impossible to hold all extraneous variables constant, because every individual has different experiences that may influence their perception, attitudes, or behaviors.

But measuring or restricting extraneous variables allows you to limit their influence or statistically control for them in your study.

Risk of low external validity

Controlled experiments have disadvantages when it comes to external validity – the extent to which your results can be generalised to broad populations and settings.

The more controlled your experiment is, the less it resembles real world contexts. That makes it harder to apply your findings outside of a controlled setting.

There’s always a tradeoff between internal and external validity . It’s important to consider your research aims when deciding whether to prioritise control or generalisability in your experiment.

Experimental designs are a set of procedures that you plan in order to examine the relationship between variables that interest you.

To design a successful experiment, first identify:

• A testable hypothesis
• One or more independent variables that you will manipulate
• One or more dependent variables that you will measure

When designing the experiment, first decide:

• How your variable(s) will be manipulated
• How you will control for any potential confounding or lurking variables
• How many subjects you will include
• How you will assign treatments to your subjects

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Control Group

Reviewed by: BD Editors

Control Group Definition

In scientific experiments, the control group is the group of subject that receive no treatment or a standardized treatment. Without the control group, there would be nothing to compare the treatment group to. When statistics refer to something being “X times more likely to happen” they are referring to the difference in the measurement between the treatment and control group. The control group provides a baseline in the experiment. The variable that is being studied in the experiment is not changed or is limited to zero in the control group. This insures that the effects of the variable are being studied. Most experiments try to add the variable back in increments to different treatment groups, to really begin to discern the effects of the variable in the system.

Ideally, the control group is subject to the same exact conditions as the treatment groups. This insures that only the effects produced by the variable are being measured. In a study of plants, for instance, all the plants would ideally be in the same room, with the same light and air conditions. In biological studies, it is also important that the organisms in the treatment and control groups come from the same population. Ideally, the organisms would all be clones of each other, to reduce genetic differences. This is the case in many artificially selected lab species, which have been selected to be very similar to each other. This ensures that the results obtained are valid.

Examples of Control Group

Testing enzyme strength.

In a simple biological lab experiment, students can test the effects of different concentrations of enzyme. The student can prepare a stock solution of enzyme by spitting into a beaker. Human spit contains the enzyme amylase, which breaks down starches. The concentration of enzyme can be varied by dividing the stock solution and adding in various amounts of water. Once various solutions of different strength enzyme have been produced, the experiment can begin.

In several treatment beakers are placed the following ingredients: starch, iodine, and the different solutions of enzyme. In the control group, a beaker is filled with starch and iodine, but no enzyme. When iodine is in the presence of starch, it turns black. As the enzyme depletes the starch in each beaker, the solution clears up and is a lighter yellow or brown color. In this way, the student can tell how long the enzymes in each beaker take to completely process the same amount of substrate. The control group is important because it will tell the student if the starch breaks down without the enzyme, which it will, given enough time.

Testing Drugs and the Placebo Effect

When drugs are tested on humans, control groups are also used. Although control groups were just considered good science, they have found an interesting phenomena in drug trials. Oftentimes, control groups in drug trials consist of people who also have the disease or ailment, but who don’t receive the medicine being tested. Instead, to keep the control group the same as the treatment groups, the patients in the control group are also given a pill. This is a sugar pill usually and contains no medicine. This practice of having a control group is important for drug trial, because it validates the results obtained. However, the control groups have also demonstrated an interesting effect, known as the placebo effect

In some drug trials, where the control group is given a fake medicine, patients start to see results. Scientists call this the placebo effect, and as of yet it is mostly unexplained. Some scientists have suggested that people get better simply because they believed they were going to get better, but this theory remains untested. Other scientists claim that unknown variables in the experiment caused the patients to get better. This theory remains unproven, as well.

Related Biology Terms

• Treatment Group – The group that receives the variable, or altered amounts of the variable.
• Variable – The part of the experiment being studied which is changed, or altered, throughout the experiment.
• Scientific Method – The steps scientist follow to ensure their results are valid and reproducible.
• Placebo Effect – A phenomenon when patients in the control group experience the same effects as those in the treatment group, though no treatment was given.

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Control Group: Definition, Examples and Types

Design of Experiments > Control Group

What is a Control Group?

An experiment is split into two groups: the experimental group and the control group. The experimental group is given the experimental treatment and the control group is given either a standard treatment or nothing. For example, let’s say you wanted to know if Gatorade increased athletic performance. Your experimental group would be given the Gatorade and your control group would be given regular water.

The conditions must be exactly the same for all members in the experiment. The only difference between members must be the item or thing you are conducting the experiment to look at. Let’s say you wanted to know if a new fertilizer makes plants grow taller. You must ensure that the lighting, water supply, size of container and other important factors are held constant for every member in every group. The only thing that differs in this case is the type of fertilizer given to the plants.

Types of Control Groups in Medical Experiments

Control groups can be subdivided into the following types (see: FDA ):

• Placebo concurrent control : one group is given the treatment, the other a placebo (“sugar pill”).
• Dose-comparison concurrent control : two different doses are administered, a different one to each group.
• No treatment concurrent control : one group is given the treatment, the other group is given nothing.
• Active treatment concurrent control : one group is given the treatment, the other group is given an existing therapy that is known to be effective.
• Historical control: only one physical group exists experimentally (the experimental group). the control group is compiled from historical data.

Which type of control group you use depends largely on what type of patients you are administering a treatment too. In many cases, it would be unethical to withhold treatment from a control group or provide a placebo.

Next : The Placebo Effect.

Beyer, W. H. CRC Standard Mathematical Tables, 31st ed. Boca Raton, FL: CRC Press, pp. 536 and 571, 2002. Agresti A. (1990) Categorical Data Analysis. John Wiley and Sons, New York. Dodge, Y. (2008). The Concise Encyclopedia of Statistics . Springer. Gonick, L. (1993). The Cartoon Guide to Statistics . HarperPerennial.

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A Common Control Group - Optimising the Experiment Design to Maximise Sensitivity

1 Statistical Science Europe, GlaxoSmithKline Pharmaceuticals, Stevenage, United Kingdom

Natasha A. Karp

2 Mouse Informatics Group, Wellcome Trust Sanger Institute, Cambridge, United Kingdom

Conceived and designed the experiments: STB NK. Performed the experiments: STB NK. Analyzed the data: STB NK. Wrote the paper: STB NK.

Associated Data

The authors confirm that all data underlying the findings are fully available without restriction. All relevant data are within the paper.

Methods for choosing an appropriate sample size in animal experiments have received much attention in the statistical and biological literature. Due to ethical constraints the number of animals used is always reduced where possible. However, as the number of animals decreases so the risk of obtaining inconclusive results increases. By using a more efficient experimental design we can, for a given number of animals, reduce this risk. In this paper two popular cases are considered, where planned comparisons are made to compare treatments back to control and when researchers plan to make all pairwise comparisons. By using theoretical and empirical techniques we show that for studies where all pairwise comparisons are made the traditional balanced design, as suggested in the literature, maximises sensitivity. For studies that involve planned comparisons of the treatment groups back to the control group, which are inherently more sensitive due to the reduced multiple testing burden, the sensitivity is maximised by increasing the number of animals in the control group while decreasing the number in the treated groups.

Introduction

The 3R's, Replacement, Reduction and Refinement, introduced as a framework for achieving the most humane treatment of experimental animals, has been widely accepted as a prerequisite for a successful animal experiment [1] . Attention on the refinement element of the framework has been growing in recent years. Refinement refers to improvements to scientific procedures and husbandry which minimise actual or potential pain, suffering, distress or lasting harm and/or improve animal welfare in situations where the use of animals is unavoidable. In 2009, Kilkenny et al . published a systematic review of published papers involving in vivo experiments and highlighted that many published experiments did not use the most appropriate experimental design. For example, in the survey only 62% of experiments that should have employed a factorial design had in fact done so [2] . Experimental design and statistical analysis fall under the refinement element of the 3R's as they reduce further experimentation and ensure that the animals used fulfil the goals of the experiment. This has led to the publication of the Animal Research: Reporting In Vivo Experiments (ARRIVE) guidelines [3] , a checklist that aims to embed good practice in the experimentation process. The impact of poor experimental design can be profound, as shown by a systematic study that found a lack of concordance between animal experiments and clinical trials [4] . The authors concluded that majority of the animal studies were of poor methodological quality. In practice though poor design and analysis is not restricted to animal experimentation and is thought to be endemic throughout scientific research [5] , [6] .

Frequently, animal researchers conduct experiments that involve multiple treatments and a common control. For example, a survey of recent PLoS ONE papers identified an R&D drug study involving multiple different treatments versus a vehicle control [10] , a study comparing high cholesterol diets to a low cholesterol diet [11] and a study comparing responses at later time points to a baseline group [12] . This type of study design is also commonly used in toxicology and safety assessment where studies are typically performed so that they can compare increasing doses of a treatment back to a control group. For example, Lee et al . [13] describe a repeated oral dose toxicity study in rats to compare three doses of KMS88009 back to a vehicle control. In these experiments comparisons back to the control will be the only comparisons that are of interest, regardless of the experimental results. It is important to note that the researcher plans which comparisons that wish to make in advance – they are examples of so-called planned comparisons [14] , as opposed to general ‘post hoc testing’ which involves making all pairwise comparisons). Planned comparisons are beneficial for two reasons. Firstly, the decision regarding which tests to perform is made before the data is collected and hence is not influenced by the observed results. In theory, this should reduce the risk of inadvertently finding false positive results in a ‘data-trawling’ exercise. Secondly, planned comparisons increase the sensitivity of the experiment as it reduces the multiple testing burden. The multiple testing burden arises because the chance of finding a false positive, for a given significance threshold, accumulates with each statistical test conducted. If all pairwise comparisons are performed, for example using an LSD (Least Significant difference) test [8] , then there is an increased risk of finding false positives. To manage this risk a more stringent threshold is applied; by making a multiple comparison adjustment to the LSD p-values. Consider the scenario with one control group and three treatments. If all groups are compared then the post-hoc testing would involve six separate pairwise statistical comparisons. However, if planned comparisons of treatments back to control are performed then this corresponds to only three separate statistical comparisons and the threshold adjustment would be less. In this paper, we shall consider the implications on the choice of design when the researcher knows in advance which comparisons they wish to make.

When constructing experimental designs that involve a number of treatment groups and a control group, interest rightly focuses on the sample size that is required in each of the experimental (treatment and control) groups. It appears to be standard practice to assign the same number of animals to each of the experimental groups (the so-called ‘balanced’ designs). Such practice is perhaps encouraged by sample size calculation software, where typically one sample size is recommended across all groups [15] , [16] . The statistical test applied also influences the sample size required. A common approach used to analyse data generated from these experiments, assuming the parametric assumptions hold, is to compare the treatment group means to the control group mean, using either t -tests, Analysis of Variance followed by Dunnett's test or applying a multiple comparison adjustment to the LSD p-values. It is therefore common practice to perform a sample size calculation under the assumption that the statistical analysis will be performed using one of these tests [17] .

In this paper, we shall use optimal design theory to investigate the effects of varying the replication of the experimental groups. We shall assume that the data will be analysed using either multiple t -tests or Analysis of Variance followed by a suitable multiple comparison procedure. Crucially we differentiate between the experimental situations where the researcher only plans to compare the treatments back to control and when they plan to make all pairwise comparisons. We will focus on the former case, and highlight how different experimental designs result in different levels of statistical power.

Two approaches are considered in this paper to investigate the effect of varying the control group replication; a theoretical investigation and a power comparison.

Theoretical approach to maximising sensitivity

For the theoretical investigation, we need to make a few assumptions. While restrictive, many animal experiments satisfy these assumptions. We assume that:

• The variability of the responses is the same across all experimental groups. In practice the response may require a transformation in order to satisfy this condition.
• The parametric assumptions hold (for example, the responses are numerical, independent, continuous and the residuals are normally distributed) and hence a parametric test, such as the t -test or Analysis of Variance followed by pairwise comparisons, will be used to compare the experimental groups.

By considering the predicted standard error of the estimates of the comparisons of interest, when using a given experimental design, it is possible to compare and contrast different designs. The more efficient the design, the smaller the predicted standard errors will be and hence the statistical tests will be more sensitive. For a given total number of animals, we use mathematical arguments (see S1 Derivations for more details) to investigate how varying the replication of the control group influences these standard errors.

Power analysis assessment

To highlight the practical implications of using different experimental designs, we investigate the statistical power that can be achieved when comparing all treatments back to a single common control using planned comparisons. The tests within this manuscript are not adjusted for multiplicity, as the adjustment needed varies between the analysis scenarios and adds complexity to the analysis. The absolute level of statistical power is not of direct interest; rather we are interested in investigating how varying the experimental design (control group replication) influences its statistical power.

Using the mathematical arguments given in S1 Derivations we can, for a variety of scenarios, assess the optimal replication in the control group to achieve for maximum sensitivity. We assume that the researcher is running an experiment that satisfies the five conditions discussed in the methods.

The estimates of the pairwise comparisons of interest are as precise as possible if:

In other words, as expected by symmetry, as all groups are involved in the same number of comparisons, the same number of animals should be allocated to each of the experimental groups (treatment groups and the control group).

From consideration of these two scenarios, we can see the optimal design depends on the goal of the experiment. With the defined planned comparisons in Scenario 1, an unbalanced design with more animals allocated to the control group results in comparisons that are estimated more precisely. This gain in sensitivity is at the expense of treatment comparisons that the researcher does not plan to make. In other words, the pairwise comparisons of interest are more precise, everything else being equal, if one design is employed when compared to another. From a less mathematical point of view, these results make sense as the control group is used more often than the other treatment means, and hence it is important to have a precise estimate of the control group mean.

Power analysis assessment for Scenario 1

We shall now consider Scenario 1 in more detail. The previous analysis identified the optimal design to maximise sensitivity and we now focus on quantifying the impact on the statistical power of the various designs.

The variability of the responses is fixed at 2.25. Three strategies for selecting the size of the control group were considered: (i) Optimal, according to the theoretical derivation, (ii) Equal to the treatment groups and (iii) Less than, where the control group replication is less than the treatment groups.

The difference between the treatment and control groups is fixed at 2. Three strategies for selecting the size of the control group were considered: (i) Optimal, according to the theoretical derivation, (ii) Equal to the treatment groups and (iii) Less than, where the control group replication is less than the treatment groups.

From Tables 1 and ​ and2 2 it can be seen that, in the situations considered, a gain in statistical power of between 0.16% and 7.02% (with a median of 3.12%) can be achieved when using the mathematically optimal replication of controls, compared to replicating all groups equally. This benefit is reduced if the statistical power obtained when using both designs approaches 100%. While such improvements are perhaps of marginal practical importance, especially in suitably powered experiments, it is still the case that a slight change to the experimental design can result in more sensitive statistical tests without increasing the total number of animals used.

Perhaps more strikingly, from Table 1 and ​ and2 2 it can be seen that there is a significant drop in statistical power if the number of animals in the control group is less than the number in the treatment groups. For example, if a design is required to compare four treatments with a control, the size of biologically relevant effect is 2 and the variability of the responses is 2.25, then a 30% increase in power can be achieved if the optimal replication of animals is used, when compared to a design where there are fewer animals in the control group compared to the treated groups.

Conclusions

A review of the literature seems to imply the researcher should use a balanced design with the same number of animals allocated to each experimental group. For example, Ruxton and Colegrave [19] state “Always aim to balance your experiment, unless you have a very good reason not to”. In many statistical texts the sample size calculation is performed when the experimental design consists of only two groups. In this case the balanced design is usually a sensible choice. Unfortunately designs used in practice are rarely so straightforward, and hence the orthodox strategy may not always be appropriate.

Another strategy that researchers may follow when designing their experiments is to reduce the number of animals in the control group compared to the treatment groups. This approach is usually taken because the researcher has access to historical control data and feels that this knowledge implies fewer concurrent controls are needed. There has been much written about the benefit of using historical control data when assessing the effect of treatments [20] though it does not replace concurrent controls. Prior knowledge, perhaps obtained from a historical control database, can also be incorporated into the statistical analysis using a Bayesian analysis paradigm. This approach has been successfully applied in clinical research, although such studies usually involve comparing a single treatment to a control or placebo [21] . While there are certain benefits to comparing multiple treatments to a historical control group, this work highlights that a study with both concurrent and historic controls does not necessarily imply that fewer animals can be included in a concurrent control. When treatments are compared using the popular statistical analysis approaches discussed in the methods section, we have demonstrated that having more animals in the treatment groups, compared to the control group, can lead to a significant reduction in statistical power regardless of the benefits of using historical control information.

In this paper we have assumed that the variability is the same in all experimental groups. In practice this assumption may not hold. For example, in biological responses it is common for the variability to increase with the size of the response. Furthermore, responses that are bounded (e.g. percentages which cannot go below 0 or above 100) tend to be less variable as a boundary is approached. In such cases, there are statistical analysis strategies that can be applied, but they are beyond the scope of this paper. An alternative strategy, commonly recommended [8] , [14] , [22] , is to investigate the use of non-linear data transformations to “correct” the data which then allow application of the methods discussed within this paper. For example, the arcsine transformation for percentage data, square root transformation for count data and log transformation if the variability increases as the response increases.

The arguments presented in this paper, also assume that any attrition due to experimental procedures is expected to be the same across all groups. If the researcher believes, for example, that they are likely to lose more animals in the treated groups, then they may wish to adjust the initial sample sizes so that the sample sizes achieved at the end of the study should result in a design that is close to the optimal design.

In practice, if the experiment is to be successful, many considerations should be taken into account when constructing a design. Issues such as practical constraints on the experimental material, financial pressures and ethical issues should be taken into account alongside optimal statistical design theory. In this paper we have aimed to highlight what a theoretically optimal experimental design, all things being equal, would be. The researcher should use this knowledge, in conjunction with other constraints, when planning their experiment.

Supporting Information

S1 derivations.

Determining the optimum control group replication.

S2 Derivations

Determining the statistical power.

Acknowledgments

We would like to dedicate this paper to the late Robert Kempson who brought this problem and solution to our attention.

Funding Statement

This work was supported by the National Institutes of Health ( www.nih.gov ), grant number 1 U54 HG006370-01 (Natasha Karp). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

Data Availability

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Understanding Control Groups in Testing

• Published on September 18, 2018
• Views 87.58k

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Scientists have a method to their madness, conveniently known as the scientific method. Any experimenter worth their salt will metaphorically season their experiment with what we in the business call a control group. So, what is a control group, scientifically speaking? A control group is a statistically significant portion of participants in an experiment that are shielded from exposure to variables. In a pharmaceutical drug study, for example, the control group receives a placebo, which has no effect on the body. 1 Since there is a lot of room for error within the scientific method, having a control group present is vital for accurate analysis. One common source of error within experimentation is confirmation bias. Confirmation bias is the tendency for experimenters to give their expected outcome too much weight when measuring results, leading to inaccurate findings. This may lead you to wonder, how are control groups used in fields other than the physical sciences? And, how does a control group help combat biases? Learn more about what a control group is or jump to our infographic for a visual guide to use control groups in A/B testing. 

Control Group Example

Control Groups in A/B Testing

Usually, an A/B test compares two variations of an advertisement, feature, message, or other user experience. A control group is one aspect of A/B testing that is often overlooked. It’s almost as if A/B testing should really have been called A/B/C testing, the “C” standing for the control group. Any software business seeking the winning solution for a new implementation should use A/B testing, absolutely. But where businesses fail in this process is to measure against a benchmark. In the case of software testing, a control group would be that benchmark. Almost a precursor to the axiom, “if it ain’t broke, don’t fix it,” a control group will determine if it indeed “ain’t broken.”

Control Groups in Multivariate Tests

Why Use a Control Group? (Hint: It’s Important)

Control Group vs. Control Variable

When testing marketing campaigns, it’s not uncommon for people to confuse a control group with a control variable. As you now know, a control group is a segment of participants (users) who are not exposed to any variables being tested. A control variable , on the other hand, is the aspect of the actual experiment that does not change. 3 As an easy example of a control variable, let us assume researchers on the marketing team are interested in finding the best call to action copy for their exit intent popup message. Best practice for testing variables is to keep all other variables constant, otherwise known as controlled variables. Images, colors, and buttons would all remain the same while each copy variation is tested, increasing the accuracy of results.

Control Group Segmentation

Measuring Control Group Effectiveness

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What Is a Control Variable? Definition and Examples

A control variable is any factor that is controlled or held constant during an experiment . For this reason, it’s also known as a controlled variable or a constant variable. A single experiment may contain many control variables . Unlike the independent and dependent variables , control variables aren’t a part of the experiment, but they are important because they could affect the outcome. Take a look at the difference between a control variable and control group and see examples of control variables.

Importance of Control Variables

Remember, the independent variable is the one you change, the dependent variable is the one you measure in response to this change, and the control variables are any other factors you control or hold constant so that they can’t influence the experiment. Control variables are important because:

• They make it easier to reproduce the experiment.
• The increase confidence in the outcome of the experiment.

For example, if you conducted an experiment examining the effect of the color of light on plant growth, but you didn’t control temperature, it might affect the outcome. One light source might be hotter than the other, affecting plant growth. This could lead you to incorrectly accept or reject your hypothesis. As another example, say you did control the temperature. If you did not report this temperature in your “methods” section, another researcher might have trouble reproducing your results. What if you conducted your experiment at 15 °C. Would you expect the same results at 5 °C or 35 5 °C? Sometimes the potential effect of a control variable can lead to a new experiment!

Sometimes you think you have controlled everything except the independent variable, but still get strange results. This could be due to what is called a “ confounding variable .” Examples of confounding variables could be humidity, magnetism, and vibration. Sometimes you can identify a confounding variable and turn it into a control variable. Other times, confounding variables cannot be detected or controlled.

Control Variable vs Control Group

A control group is different from a control variable. You expose a control group to all the same conditions as the experimental group, except you change the independent variable in the experimental group. Both the control group and experimental group should have the same control variables.

Control Variable Examples

Anything you can measure or control that is not the independent variable or dependent variable has potential to be a control variable. Examples of common control variables include:

• Duration of the experiment
• Size and composition of containers
• Temperature
• Sample volume
• Experimental technique
• Chemical purity or manufacturer
• Species (in biological experiments)

For example, consider an experiment testing whether a certain supplement affects cattle weight gain. The independent variable is the supplement, while the dependent variable is cattle weight. A typical control group would consist of cattle not given the supplement, while the cattle in the experimental group would receive the supplement. Examples of control variables in this experiment could include the age of the cattle, their breed, whether they are male or female, the amount of supplement, the way the supplement is administered, how often the supplement is administered, the type of feed given to the cattle, the temperature, the water supply, the time of year, and the method used to record weight. There may be other control variables, too. Sometimes you can’t actually control a control variable, but conditions should be the same for both the control and experimental groups. For example, if the cattle are free-range, weather might change from day to day, but both groups have the same experience. When you take data, be sure to record control variables along with the independent and dependent variable.

• Box, George E.P.; Hunter, William G.; Hunter, J. Stuart (1978). Statistics for Experimenters : An Introduction to Design, Data Analysis, and Model Building . New York: Wiley. ISBN 978-0-471-09315-2.
• Giri, Narayan C.; Das, M. N. (1979). Design and Analysis of Experiments . New York, N.Y: Wiley. ISBN 9780852269145.
• Stigler, Stephen M. (November 1992). “A Historical View of Statistical Concepts in Psychology and Educational Research”. American Journal of Education . 101 (1): 60–70. doi: 10.1086/444032

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What Is a Controlled Experiment?

Definition and Example

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• Ph.D., Biomedical Sciences, University of Tennessee at Knoxville
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A controlled experiment is one in which everything is held constant except for one variable . Usually, a set of data is taken to be a control group , which is commonly the normal or usual state, and one or more other groups are examined where all conditions are identical to the control group and to each other except for one variable.

Sometimes it's necessary to change more than one variable, but all of the other experimental conditions will be controlled so that only the variables being examined change. And what is measured is the variables' amount or the way in which they change.

Controlled Experiment

• A controlled experiment is simply an experiment in which all factors are held constant except for one: the independent variable.
• A common type of controlled experiment compares a control group against an experimental group. All variables are identical between the two groups except for the factor being tested.
• The advantage of a controlled experiment is that it is easier to eliminate uncertainty about the significance of the results.

Example of a Controlled Experiment

Let's say you want to know if the type of soil affects how long it takes a seed to germinate, and you decide to set up a controlled experiment to answer the question. You might take five identical pots, fill each with a different type of soil, plant identical bean seeds in each pot, place the pots in a sunny window, water them equally, and measure how long it takes for the seeds in each pot to sprout.

This is a controlled experiment because your goal is to keep every variable constant except the type of soil you use. You control these features.

Why Controlled Experiments Are Important

The big advantage of a controlled experiment is that you can eliminate much of the uncertainty about your results. If you couldn't control each variable, you might end up with a confusing outcome.

For example, if you planted different types of seeds in each of the pots, trying to determine if soil type affected germination, you might find some types of seeds germinate faster than others. You wouldn't be able to say, with any degree of certainty, that the rate of germination was due to the type of soil. It might as well have been due to the type of seeds.

Or, if you had placed some pots in a sunny window and some in the shade or watered some pots more than others, you could get mixed results. The value of a controlled experiment is that it yields a high degree of confidence in the outcome. You know which variable caused or did not cause a change.

Are All Experiments Controlled?

No, they are not. It's still possible to obtain useful data from uncontrolled experiments, but it's harder to draw conclusions based on the data.

An example of an area where controlled experiments are difficult is human testing. Say you want to know if a new diet pill helps with weight loss. You can collect a sample of people, give each of them the pill, and measure their weight. You can try to control as many variables as possible, such as how much exercise they get or how many calories they eat.

However, you will have several uncontrolled variables, which may include age, gender, genetic predisposition toward a high or low metabolism, how overweight they were before starting the test, whether they inadvertently eat something that interacts with the drug, etc.

Scientists try to record as much data as possible when conducting uncontrolled experiments, so they can see additional factors that may be affecting their results. Although it is harder to draw conclusions from uncontrolled experiments, new patterns often emerge that would not have been observable in a controlled experiment.

For example, you may notice the diet drug seems to work for female subjects, but not for male subjects, and this may lead to further experimentation and a possible breakthrough. If you had only been able to perform a controlled experiment, perhaps on male clones alone, you would have missed this connection.

• Box, George E. P., et al.  Statistics for Experimenters: Design, Innovation, and Discovery . Wiley-Interscience, a John Wiley & Soncs, Inc., Publication, 2005. 
• Creswell, John W.  Educational Research: Planning, Conducting, and Evaluating Quantitative and Qualitative Research . Pearson/Merrill Prentice Hall, 2008.
• Pronzato, L. "Optimal experimental design and some related control problems". Automatica . 2008.
• Robbins, H. "Some Aspects of the Sequential Design of Experiments". Bulletin of the American Mathematical Society . 1952.
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