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Neonatology articles from across Nature Portfolio

Latest research and reviews, neonatal complications and risk factors associated with assisted vaginal delivery.

  • Saifon Chawanpaiboon
  • Vitaya Titapant
  • Julaporn Pooliam

neonatal research topics 2022

Continuous monitoring using thermography can capture the heat oscillations maintaining body temperature in neonates

  • Aya Morimoto
  • Shinji Nakamura
  • Takashi Kusaka

neonatal research topics 2022

Global longitudinal strain is an informative index of left ventricular performance in neonates receiving intensive care

  • Enrico Petoello
  • Alice Iride Flore
  • Benjamim Ficial

neonatal research topics 2022

Long-term impact of late pulmonary hypertension requiring medication in extremely preterm infants with severe bronchopulmonary dysplasia

  • Yun Sil Chang

neonatal research topics 2022

Application of machine learning algorithms for accurate determination of bilirubin level on in vitro engineered tissue phantom images

  • Jiayao Huang

neonatal research topics 2022

Impact of intrapartum oxytocin administration on neonatal sucking behavior and breastfeeding

  • Machiko Omaru
  • Setsu Kajiwara
  • Seiichi Morokuma

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neonatal research topics 2022

Prenatal treatment for Pompe’s disease

To prevent irreversible organ damage, an infant with early-onset Pompe’s disease was treated in utero; early data suggest improved outcomes and safety of this approach.

  • Karen O’Leary

neonatal research topics 2022

First step to cell therapy for ischemic stroke in newborns

In a first-in-human study, intranasal transplantation of mesenchymal stromal cells was safe and well-tolerated in newborns who had suffered a stroke — laying the foundation for large-scale clinical trials.

neonatal research topics 2022

Genetic testing in the neonatal ICU

First-line whole-genome sequencing may lead to more-focused clinical management for infants with a suspected genetic disease.

Bending the arc for the extremely low gestational age newborn

  • DeWayne M Pursley
  • Marie C McCormick

Hope vs. caution: ethical and regulatory considerations for neonatal stem cell therapies

  • Naomi T Laventhal
  • Scott A Rivkees
  • Valerie P Opipari

Biomarkers for neonatal therapeutic studies: time for a public–private partnership

  • Scott C Denne
  • Jonathan M Davis

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Neonatal Research Publications

Division of neonatology.

Physicians and researchers from the Division of Neonatology at Children's Hospital of Philadelphia are regular contributors to clinical publications. Here, we highlight some of their recent publications.

Padula MA, Naing K, Wenger TL, Ahmad I, Coghill CH III, Wild KT, Rottgers SA, Resnick CM, Goldstein J, Ehsan Z, Watkins D, Deptula N, Lai KC, Lioy J, Gogcu S, Cielo CM. Spectrum of disease in hospitalized newborns with congenital micrognathia: a cohort of 3236 infants at North American tertiary-care intensive care units. [Published online ahead of print Oct. 23, 2023] J Pediatr.

Johng S, Licht DJ, Hedrick HL, Rintoul N, Linn RL, Gebb JS, Xiao R, Massey SL. Prenatal brain maturation is delayed in neonates with congenital diaphragmatic hernia. [Published online ahead of print Sept. 16, 2023] J Pediatr.

Danzer E, Massey SL, Flohr SJ, Mathew L, Hoffman C, Abramson A, Selenski P, Canning CE, Eppley E, Connelly JT, Herkert L, Rintoul NE, Adzick NS, Abend NS, Hedrick HL. Extracorporeal membrane oxygenation for neonates with congenital diaphragmatic hernia: prevalence of seizures and outcomes. Pediatr Crit Care Med. 2023;24(5):e224-e235.

Salazar EG, Montoya-Williams D, Passarella M, McGann C, Paul K, Murosko D, Peña MM, Ortiz R, Burris HH, Lorch SA, Handley SC. County-level maternal vulnerability and preterm birth in the US. JAMA Netw Open. 2023;6(5):e2315306.

Bansal A, Cherbuin N, Leach L, Simmons RA, Nolan CJ. Wildfires and COVID-19: syndemic impact on maternal and child health. [Published online ahead of print Aug. 30, 2023] Trends Endocrinol Metab.

Jensen EA, Wiener LE, Rysavy MA, Dysart KC, Gantz MG, Eichenwald EC, Greenberg RG, Harmon HM, Laughon MM, Watterberg KL, Walsh MC, Yoder BA, Lorch SA, DeMauro SB; Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. Assessment of corticosteroid therapy and death or disability according to pretreatment risk of death or bronchopulmonary dysplasia in extremely preterm infants. JAMA Netw Open. 2023;6(5):e2312277.

Coggins SA, Willis Z, Benjamin DK, Mukhopadhyay S, Laughon M, Greenberg RG, Clark RH, Puopolo K. Early antibiotic exposure in very-low birth weight infants and infection risk at 3-7 days after birth. J Perinatol. 2023;43(9):1158-1165.

Wild KT, Mathew L, Hedrick HL, Rintoul NE, et al. Respiratory function after birth in infants with congenital diaphragmatic hernia. Arch Dis Child Fetal Neonatal Ed. 2023;108(5):535-539.

Dulmovits BM, Wild KT, Flibotte JJ, Lambert MP, Kwiatkowski J, Thom CS. Neonatal thrombocytopenia as a presenting finding in de novo pyruvate kinase deficiency. Neonatology. 2023;120(5):661-665.

Carr LH, Christ L, Ferro DF. The electronic health record as a quality improvement tool: exceptional potential with special considerations. Clin Perinatol. 2023;50(2):473-488.

Bapat R, Duran M, Piazza A, Pallotto EK, Joe P, Chuo J, Mingrone T, Hawes J, Powell M, Falciglia GH, Grover TR, Rintoul N, MacPherson MJ, Rose A, Brozanski B: A multicenter collaborative to improve postoperative pain management in the NICU. Pediatrics. 2023;152(2):e2022059860.

Fraga MV, Dysart KC, Stoller JZ, Huber M, Fedec A, MercerRosa L, Kirpalani H. Echocardiographic assessment of pulmonary arterial hypertension following inhaled nitric oxide in infants with severe bronchopulmonary dysplasia. Neonatology. 2023;120(5):633-641.

Janet Lioy, Mike Padula, and Taylor Wild - Spectrum of disease in hospitalized newborns with congenital micrognathia: a cohort of 3236 infants at North American tertiary-care intensive care units- The Journal of Pediatrics

Thom CS, Davenport P, Fazelinia H, Soule-Albridge E, Liu Z-J, Zhang H, Feldman HA, Ding H, Roof J, Spruce LA, Ischiropoulos H, Sola-Visner M Quantitative label-free mass spectrometry reveals content and signaling differences between neonatal and adult platelets, Journal of Thrombosis and Haemostasis (2024), doi: https://doi.org/10.1016/j.jtha.2023.12.022

Yang N, Quick HS, Melly SJ, Mullin AM, Zhao Y, Edwards J, Clougherty JE, Schinasi LH, Burris HH. Spatial Patterning of Spontaneous and Medically Indicated Preterm Birth in Philadelphia. Am J Epidemiol. 2023 Nov 3:kwad207. doi: 10.1093/aje/kwad207. Online ahead of print. PMID: 37939071 https://pubmed.ncbi.nlm.nih.gov/37939071/

Nelson O, Rintoul NE, Tan JM, Simpao AF, Chuo J, Hedrick HL, Duran MS, Makeneni S, Devine M, Cao L, Stricker PA. Surgical neonates: A retrospective review of procedures and postoperative outcomes at a quaternary children's hospital. Paediatr Anaesth. 2023 Dec 25. doi: 10.1111/pan.14827. Epub ahead of print. PMID: 38146211.

Danzer E, Schreiber JE, Hoffman C, Mathew L, Flohr SJ, Eppley E, Land SD, Herkert L, Rintoul NE, Adzick NS, Hedrick HL. Prevalence and patterns of executive function, adaptive function, and behavioral outcomes in preschool and school age children with congenital diaphragmatic hernia. Early Hum Dev. 2023 Dec 9;188:105914. doi: 10.1016/j.earlhumdev.2023.105914. Epub ahead of print. PMID: 38103310.

Wild KT, Hedrick HL, Ades AM, Fraga MV, Avitabile CM, Gebb JS, Oliver ER, Coletti K, Kesler EM, Van Hoose KT, Panitch HB, Johng S, Ebbert RP, Herkert LM, Hoffman C, Ruble D, Flohr S, Reynolds T, Duran M, Foster A, Isserman RS, Partridge EA, Rintoul NE. Update on Management and Outcomes of Congenital Diaphragmatic Hernia. J Intensive Care Med. 2023 Nov 6:8850666231212874. doi: 10.1177/08850666231212874. Epub ahead of print. PMID: 37933125.

Goldshore M, Land S, Flohr S, Mathew L, Reynolds T, Eppley E, Rintoul N, Gebb J, Howell L, Adzick NS, Hedrick H. The Impact of Comprehensive Fetal Care on Mortality of Children With Congenital Diaphragmatic Hernia when Delivery is Co-located in a Pediatric Hospital. J Pediatr Surg. 2023 Sep 27:S0022-3468(23)00577-8. doi: 10.1016/j.jpedsurg.2023.09.039. Epub ahead of print. PMID: 37914590.

Bose SK, Stratigis JD, Ahn N, Pogoriler J, Hedrick HL, Rintoul NE, Partridge EA, Flake AW, Khalek N, Gebb J, Teefey CP, Soni S, Hamaguchi R, Moldenhauer J, Adzick NS, Peranteau WH. Prenatally Diagnosed Large Lung Lesions: Timing of Resection and Perinatal Outcomes. J Pediatr Surg. 2023 Dec;58(12):2384-2390. doi: 10.1016/j.jpedsurg.2023.09.002. Epub 2023 Sep 9. PMID: 37813715.

Johng S, Licht DJ, Hedrick HL, Rintoul N, Linn RL, Gebb JS, Xiao R, Massey SL. Prenatal Brain Maturation is Delayed in Neonates with Congenital Diaphragmatic Hernia. J Pediatr. 2024 Jan;264:113738. doi: 10.1016/j.jpeds.2023.113738. Epub 2023 Sep 16. PMID: 37722557.

Orlinsky R, Land S, Flohr S, Rintoul N, Goldshore M, Hedrick HL. Birth Admission Length-of-Stay and Hospital Readmission in Children With Congenital Diaphragmatic Hernia. J Pediatr Surg. 2023 Dec;58(12):2368-2374. doi: 10.1016/j.jpedsurg.2023.08.002. Epub 2023 Aug 9. PMID: 37659921.

Linden AF, Howk AA, Billimoria Z, Devine M, DiGeronimo R, Gray B, Hamrick SE, Keene SD, Rintoul N, Mahmood B; Children's Hospitals Neonatal Consortium (CHNC). Neonatal Carotid Artery and Internal Jugular Vein Management Practices at Extracorporeal Membrane Oxygenation Decannulation: No Standard Approach. J Pediatr Surg. 2023 Nov;58(11):2196-2200. doi: 10.1016/j.jpedsurg.2023.07.007. Epub 2023 Jul 24. PMID: 37573253.

Bapat R, Duran M, Piazza A, Pallotto EK, Joe P, Chuo J, Mingrone T, Hawes J, Powell M, Falciglia GH, Grover TR, Rintoul N, MacPherson MJ, Rose A, Brozanski B. A Multicenter Collaborative to Improve Postoperative Pain Management in the NICU. Pediatrics. 2023 Aug 1;152(2):e2022059860. doi: 10.1542/peds.2022-059860. PMID: 37409386.

Avitabile CM, Flohr S, Mathew L, Wang Y, Ash D, Frank DB, Tingo JE, Rintoul NE, Hedrick HL. Quantitative Measures of Right Ventricular Size and Function by Echocardiogram Correlate with Cardiac Catheterization Hemodynamics in Congenital Diaphragmatic Hernia. J Pediatr. 2023 Oct;261:113564. doi: 10.1016/j.jpeds.2023.113564. Epub 2023 Jun 15. PMID: 37329980.

Danzer E, Massey SL, Flohr SJ, Mathew L, Hoffman C, Abramson A, Selenski P, Canning CE, Eppley E, Connelly JT, Herkert L, Rintoul NE, Adzick NS, Abend NS, Hedrick HL. Extracorporeal Membrane Oxygenation for Neonates With Congenital Diaphragmatic Hernia: Prevalence of Seizures and Outcomes. Pediatr Crit Care Med. 2023 May 1;24(5):e224-e235. doi: 10.1097/PCC.0000000000003197. Epub 2023 Feb 22. PMID: 37140337; PMCID: PMC10160669.

De Bie FR, Avitabile CM, Flohr S, Land S, Mathew L, Wang Y, Ash D, Rintoul NE, Hedrick HL. Treprostinil in Neonates with Congenital Diaphragmatic Hernia-Related Pulmonary Hypertension. J Pediatr. 2023 Aug;259:113420. doi: 10.1016/j.jpeds.2023.113420. Epub 2023 Apr 12. PMID: 37059388.

Callaway DA, Wang Y, Lingappan K, Pogoriler JE, Laje P, Nilan K, Kirpalani H, Zhang H. Lung Biopsy in Infants with Severe Bronchopulmonary Dysplasia. Pediatr Pulmonol. 2023 Jul;58(7):2068-2075. doi: 10.1002/ppul.26433. Epub 2023 May 3.PMID: 37133233

Zapatero ZD, Zhang H, Zandifar A, Nilan KA, Calabria AC, Swanson JW, Vossough A, Taylor JA, Lang SS, Bartlett SP. A Novel Phenotype of Calvarial Thickening and Increased Rates of Premature Calvarial Suture Closure in Children with Chronic Lung Disease. J Craniofac Surg. 2023 Jul 11. doi: 10.1097/SCS.0000000000009528. PMID: 37431930

Kather C, Shofer FS, Park JI, Bogen D, Pierce SR, Kording K, Nilan K, Zhang H, Prosser LA and Johnson MJ. Quantifying Interaction with Robotic Toys in Pre-term and Full-term Infants. Front. Pediatr. 11:1153841.doi: 10.3389/fped.2023.1153841

Low Birth Weight Babies and Disability (2023). National Academies of Sciences, Engineering, and Medicine; Health and Medicine Division; Board on Health Care Services; Committee on the Identification and Prognosis of Low Birth Weight Babies in Disability Determinations (Andrews BL, Casteix JA, Caughey AB, Cordero JF, Coster WJ, Devaskar SU, Duncan AF, Gaebler-Spira D, Greene MM, Koop JI, Kuo DZ, Lipkin PH, Monihan HM, Schmidt L). Walter Frontera, Carol Mason Spicer, and Austen Applegate, Editors.

Lapidaire W, Proaño A, Blumenberg C, Loret de Mola C, Delgado CA, Del Castillo D, Wehrmeister FC, Gonçalves H, Gilman RH, Oberhelman RA, Lewandowski AJ, Wells JCK, Miranda JJ. Effect of preterm birth on growth and blood pressure in adulthood in the Pelotas 1993 cohort. Int J Epidemiol. 2023 Dec 25;52(6):1870-1877. doi: 10.1093/ije/dyad084. PMID: 37354551; PMCID: PMC10749774.

Karavite DJ, Harris MC, Grundmeier RW, Srinivasan L, Shaeffer GP, Muthu N. Using a sociotechnical model to understand challenges with sepsis recognition among critically ill infants. ACI Open. 2022;6:e57-e65.

Kosyk MS, Carlson AR, Zapatero ZD, Kalmar CL, Cielo CM, Lioy J, Bartlett SP, Taylor JA, Swanson JW. Mandibular Distraction Osteogenesis for Tongue-Based Airway Obstruction Without Micrognathia. Ann Plast Surg. 2022 Jan 1;88(1):54-58. doi: 10.1097/SAP.0000000000002891. PMID: 34176894.

Mortality, In-Hospital Morbidity, Care Practices, and 2-Year Outcomes for Extremely Preterm Infants in the US, 2013-2018. Bell EF, Hintz SR, Hansen NI, Bann CM, Wyckoff MH, DeMauro SB, Walsh MC, Vohr BR, Stoll BJ, Carlo WA, Van Meurs KP, Rysavy MA, Patel RM, Merhar SL, Sánchez PJ, Laptook AR, Hibbs AM, Cotten CM, D'Angio CT, Winter S, Fuller J, Das A; Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. JAMA. 2022 Jan 18;327(3):248-263. doi: 10.1001/jama.2021.23580. PMID: 35040888

Nic Bamat, Scott Lorch, Eric Eichenwald Association between postmenstrual age and furosemide dosing practices in very preterm infants. Bamat NA, Thompson EJ, Greenberg RG, Lorch SA, Zuppa AF, Eichenwald EC, Tolia VN, Clark RH, Smith PB, Hornik CP, Lang JE, Laughon MM. J Perinatol. 2022 Jan 24. doi: 10.1038/s41372-022-01320-w. Online ahead of print. PMID: 35075306.

Bamat NA, Thompson EJ, Greenberg RG, Lorch SA, Zuppa AF, Eichenwald EC, Tolia VN, Clark RH, Smith PB, Hornik CP, Lang JE, Laughon MM. Association between postmenstrual age and furosemide dosing practices in very preterm infants. [Published online ahead of print Jan. 24, 2022] J Perinatol.

Lee CD, Nelin L, Foglia EE. Neonatal Resuscitation in 22-Week Pregnancies. NEngl J Med. 2022 Jan 27;386(4):391-393. doi: 10.1056/NEJMclde2114954. PMID:35081286.

Mahmood B, Murthy K, Rintoul N, Weems M, Keene S, Brozanski B, DiGeronimo R, Haberman B, Hedrick H, Gien J, Seabrook R, Ali N, Chapman R, Daniel J, Harrison A, Johnson Y, Porta NFM, Uhing M, Zaniletti I, Grover TR; Children's Hospitals Neonatal Consortium: Predicting treatment of pulmonary hypertension at discharge in infants with congenital diaphragmatic hernia. J Perinatol January  2022.

O'Leary EN, Edwards JR, Srinivasan A, Neuhauser MM, Soe MM, Webb AK, Edwards EM, Horbar JD, Soll RF, Roberts J, Hicks LA, Wu H, Zayack D, Braun D, Cali S, Edwards WH, Flannery DD, Fleming-Dutra KE, Guzman-Cottrill JA, Kuzniewicz M, Lee GM, Newland J, Olson J, Puopolo KM, Rogers SP, Schulman J, Septimus E, Pollock DA. National Healthcare Safety Network 2018 Baseline Neonatal Standardized Antimicrobial Administration Ratios. Hosp Pediatr. 2022 Feb 1;12(2):190-198. doi: 10.1542/hpeds.2021-006253. PubMed PMID: 35075483; PubMed Central PMCID: pending

Montoya-Williams D, Wallis KE, Duncan AF. Best practices for the conduct of antiracist research: Time for formal, tailored curriculums. JAMA Pediatr. 2022 Feb 14. doi: 10.1001/jamapediatrics.2021.6315.

Callahan KP, Flibotte J, Skraban C, Wild KT, Joffe S, Munson D, Feudtner C. How neonatologists use genetic testing: findings from a national survey. J Perinatol. 2022 Feb;42(2):260-261. doi: 10.1038/s41372-021-01283-4. Epub 2021 Nov 30. PMID: 34848850; PMCID: PMC8825701.

Yang KC, Hu HH, Ades AM. The Hidden Impact of Neonatology Boot Camp: A Qualitative Study. Simul Healthc. 2022 Aug 1;17(4):256-263. doi: 10.1097/SIH.0000000000000639. Epub 2022 Mar 1. PMID: 35220389.

Mukhopadhyay S, Briker SM, Flannery DD, Dhudasia MB, Coggins SA, Woodford E, Walsh EM. Li S, Puopolo KM, Kuzniewicz MW. Time to Positivity of Blood Cultures in Neonatal Late-Onset Bacteremia. Arch Dis Child – Fetal Neonat Ed. Published Online First: 10 March 2022. doi: 10.1136/archdischild-2021-323416

Salazar E, Handley SC, Greenberg LT, Edwards EM, Lorch SA. “Measuring Quality of Care in Moderate and Late Preterm Infants.” J Perinatology. 2022. Mar 30. doi: 10.1038/s41372-022-01377-7. PMID: 35354940.

Proaño A, Keir A, Campbell DM, Courchia B, Narvey M, Bamat NA. #neoTwitter: evaluation of its use within the neonatal-perinatal community. J Perinatol.2022 Oct;42(10):1409-1411. doi: 10.1038/s41372-022-01373-x. Epub 2022 Mar 31. PubMed PMID: 35361886; PubMed Central PMCID: PMC9522885.

Flannery DD, Puopolo KM, Hansen NI, Gerber JS, Sánchez PJ, Stoll BJ, for the Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. Antimicrobial Susceptibility Profiles Among Neonatal Early-Onset Sepsis Pathogens. Pediatr Infect Dis J. March 2022 Mar; 41(3):263-271/ PMID: 34862339; PubMed Central PMCID: PMC8831448

Puopolo KM, Mukhopadhyay S, Hansen NI, Flannery DD, Greenberg RG, Sanchez PJ, Bell EF, DeMauro SB, Wyckoff MH, Eichenwald EC, Stoll BJ, for the Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. Group B Streptococcal Infection in Extremely Preterm Neonates and Neurodevelopmental Outcomes at 2 Years. Clin Infect Dis. March 2022. PubMed PMID: pending; PubMed Central PMCID: pending. doi:10.1093/CID/CIAC222. Online ahead of print.

Duncan AF, Malleske DT, Maitre NL. Use of Antenatal Corticosteroids for Risk of Preterm Birth-Is Timing Everything? JAMA Pediatr. 2022 Apr 11:e220480. doi: 10.1001/jamapediatrics.2022.0480. Epub ahead of print. PMID: 35404440.61.

Gross I, Clapper T, Ramachandra G, Thomas A, Ades A, Walsh B, Kreuzer F, Elkin R, Wagner M, Whitfill T, Chang T, Duff J, Deutsch E, Loellgen R, Palaganas J, Fayyaz J, Kessler D, Calhoun A. Setting an agenda: Results of a consensus process on research directions in distance simulation. Simul Healthc. 2022 Apr. Online ahead of print.

Conlon TW, Yousef N, Mayordomo-Colunga J, Tissot C, Fraga MV, Bhombal S, Suryawanshi P, Villanueva AM, Siassi B, Singh Y. Establishing a risk assessment framework for point-of-care ultrasound. Eur J Pediatr. 2022 Apr;181(4):1449-1457. doi: 10.1007/s00431-021-04324-4. Epub 2021 Nov 30. PMID: 34846557; PMCID: PMC8964607.

Wild KT, Schindewolf E, Hedrick HL, Rintoul NE, Hartman T, Gebb J, Moldenhauer JS, Zackai EH, Krantz ID: The Genomics of Congenital Diaphragmatic Hernia: A 10-Year Retrospective Review. J Pediatr S0022-3476(22): 00326-2, April 2022 Notes: doi: 10.1016/j.jpeds.2022.04.012. Epub ahead of print.

Kozyak BW, Fraga MV, Juliano CE, Bhombal S, Munson DA, Brandsma E, Stoller JZ, Jain A, Kesman R, Meshkati M, Noh CY, Dewitt AG, Costarino AT, Hehir DA, Groves AM. Real-Time Ultrasound Guidance for Umbilical Venous Cannulation in Neonates With Congenital Heart Disease. Pediatr Crit Care Med. 2022 May 1;23(5):e257-e266. doi: 10.1097/PCC.0000000000002919. Epub 2022 Mar 7. PMID: 35250003.

Herrick HM, Passarella M, Weimer J, Bonafide CP, DeMauro SB. Alarm Burden in Infants With Bronchopulmonary Dysplasia Monitored With Pulse Oximetry at Home. JAMA Netw Open. 2022 Jun 1;5(6):e2218367. doi: 10.1001/jamanetworkopen.2022.18367. PubMed PMID: 35737392; PubMed Central PMCID: PMC9227001

DeMauro SB, Merhar SL, Peralta-Carcelen M, Vohr BR, Duncan AF, Hintz SR. The critical importance of follow-up to school age: Contributions of the NICHD Neonatal Research Network. Semin Perinatol. 2022 Jun 10:151643.

Ramachandran S, Foglia EE, DeMauro SB, Chawla S, Brion LP, Wyckoff MH. Perinatal management: Lessons learned from the neonatal research network. Semin Perinatol. 2022 Nov;46(7):151636. doi: 10.1016/j.semperi.2022.151636. Epub 2022. Jun 10. PMID: 35835614.

Flannery DD, Zevallos Barboza A, Pfeifer MR, Hudak ML, Barnette K, Getzlaff TR, Ellington SR, Woodworth KR, Dhudasia MB, Mukhopadhyay S, Weinberg DD, Foglia EE, Puopolo KM. Perinatal COVID-19 maternal and neonatal outcomes at two academic birth hospitals. J Perinatol. 2022 Oct;42(10):1338-1345. doi: 10.1038/s41372-022-01446-x. Epub 2022 Jul 1. PMID: 35778485; PMCID: PMC9247898.

Herrick HM, Weinberg DD, James J, Murray A, Brown-Jackson L, Chaudhary A, Posencheg MA, Foglia EE. Decreasing Intubation for Ineffective Ventilation after Birth for Very Low Birth Weight Neonates. Pediatr Qual Saf. 2022 Jul-Aug;7(4):e580. doi: 10.1097/pq9.0000000000000580. eCollection 2022 Jul-Aug. PubMed PMID: 35928022; PubMed Central PMCID: PMC9345641.

Foglia EE, Weinberg DD, Te Pas AB, Dekker J, Hsu JY. Reliability of respiratory function monitor interpretation for neonatal resuscitation. Arch Dis Child Fetal Neonatal Ed. 2022 Jul 14:fetalneonatal-2022-324369. doi: 10.1136/archdischild-2022-324369. Epub ahead of print. PMID: 35835540.

Handley SC, Salazar EG, Greenberg LT, Foglia EE, Lorch SA, Edwards EM. “Variation and temporal trends in delivery room management of moderate and late preterm infants.” Pediatrics.2022. Jul 19; e2021055994. doi: 10.1542/peds.2021-055994. PMID 35851607. 

Handley SC, Salazar EG, Greenberg LT, Foglia EE, Lorch SA, Edwards EM. Variation and Temporal Trends in Delivery Room Management of Moderate and Late Preterm Infants. Pediatrics. 2022 Aug 1;150(2):e2021055994. doi: 10.1542/peds.2021-055994. PMID: 35851607; PMCID: PMC9721105.

Herrick HM, Weinberg DD, James J, Murray A, Brown-Jackson L, Chaudhary A, Posencheg MA, Foglia EE. Decreasing Intubation for Ineffective Ventilation after Birth for Very Low Birth Weight Neonates. Pediatr Qual Saf. 2022 Aug 1;7(4):e580. doi: 10.1097/pq9.0000000000000580. PMID: 35928022; PMCID: PMC9345641.

Ron, HA, Scobell R, Strong A, Salazar EG, Ganetzky R. “Congenital adrenal calcifications as the first clinical indication of sphingosine lyase insufficiency syndrome: A case report and review of the literature.” Am J Med Genet A. 2022, Aug 16. doi: 10.1002/ajmg.a.62956. PMID 35972040.

Montoya-Williams D, Duncan AF, Burris HH. Racial and ethnic perinatal and infant disparities: a comprehensive, diverse and actionable compendium [published online ahead of print, 2022 Aug 31]. Semin Perinatol. 2022;151655.

Bamat NA, Vereen RJ, Montoya-Williams D. Disparities in Lung Disease of Prematurity-When Does Exposure to Racism Begin?. JAMA Pediatr. 2022 Sep 1;176(9):845-847. doi: 10.1001/jamapediatrics.2022.2671. PubMed PMID: 35913709.

Salazar E, Paul K, Murosko D, Nguemeni Tiako MJ, Burris HH. “Preterm Birth in Historically Redlined Neighborhoods – Spatial Analysis with Individual and Community Level Factors.” J Perinatology. 2022. Sept 12. doi: 10.1038/s41372-022-01509-z.  

Bamat NA, Orians CM, Abbasi S, Morley CJ, Ross Russell R, Panitch HB, Handley SC, Foglia EE, Posencheg MA, Kirpalani H. Use of ventilation/perfusion mismatch to guide individualised CPAP level selection in preterm infants: a feasibility trial. Arch Dis Child Fetal Neonatal Ed. 2022 Sep 14;. doi: 10.1136/archdischild-2022-324474. [Epub ahead of print] PubMed PMID: 36104165.

Bamat NA, Vedar C, Reilly ME, Moorthy GS, Zuppa AF. A whole blood microsampling furosemide assay: development, validation and use in a pediatric pharmacokinetic study. Bioanalysis. 2022 Aug;14(15):1025-1038. doi: 10.4155/bio-2022-0063. Epub 2022 Sep 27. PubMed PMID: 36165919; PubMed Central PMCID: PMC9540403.

Kuypers KLAM, van Zanten HA, Heesters V, Kamlin O, Springer L, Lista G, Cavigioli F, Vento M, Núñez-Ramiro A, Kuester H, Horn S, Weinberg DD, Foglia EE, Morley CJ, Davis PG, Te Pas AB. Resuscitators' opinions on using a respiratory function monitor during neonatal resuscitation. Acta Paediatr. 2022 Sep 30. doi: 10.1111/apa.16559. Epub ahead of print. PMID: 36177808.

Moussa A, Sawyer T, Puia-Dumitrescu M, Foglia EE, Ades A, Napolitano N, Glass KM, Johnston L, Jung P, Singh N, Quek BH, Barry J, Zenge J, DeMeo S, Mehrem AA, Nadkarni V, Nishisaki A; National Emergency Airway Registry for Neonates (NEARNEOS) investigators. Does videolaryngoscopy improve tracheal intubation first attempt success in the NICUs? A report from the NEAR4NEOS. J Perinatol. 2022 Sep;42(9):1210-1215. doi: 10.1038/s41372-022-01472-9. Epub 2022 Aug 3. PMID: 35922664; PMCID: PMC9362392.

Vyas-Read S, Jensen EA, Bamat N, Lagatta JM, Murthy K, Patel RM. Chronic lung disease-related mortality in the US from 1999-2017: trends and racial disparities. J Perinatol. 2022 Sep;42(9):1244-1245. doi: 10.1038/s41372-022-01468-5. Epub 2022 Jul 29. PubMed PMID: 35906284.

Singh N, Sawyer T, Johnston LC, Herrick HM, Moussa A, Zenge J, Jung P, DeMeo S, Glass K, Howlett A, Shults J, Barry J, Brei BK, Kim JH, Quek BH, Tingay D, Mehrem AA, Napolitano N, Nishisaki A, Foglia EE. Impact of multiple intubation attempts on adverse tracheal intubation associated events in neonates: a report from the NEAR4NEOS. J Perinatol. 2022 Sep;42(9):1221-1227. doi: 10.1038/s41372-022-01484-5. Epub 2022 Aug 18. PubMed PMID: 35982243.

Handley SC, Kumbhat N, Eggleston B, Foglia EE, Davis AS, Van Meurs K, Lakshminrusimha S, Walsh M, Watterberg KL, Wyckoff MH, Das A, DeMauro SB. Exposure to umbilical cord management approaches and death or neurodevelopmental impairment at 22-26 months' corrected age after extremely preterm birth. Arch Dis Child Fetal Neonatal Ed. 2022 Oct 17:fetalneonatal-2022-324565. doi: 10.1136/archdischild-2022-324565. Epub ahead of print. PMID: 36253076.

Triebwasser JE, Dhudasia MB, Mukhopadhyay S, Flannery DD, Gouma S, Hensley SE, Puopolo KM. Assessment of SARS-CoV-2 serostatus and hypertensive disorders of pregnancy. Am J Obstet Gynecol. 2022 Oct;227(4):664-666.e1. doi: 10.1016/j.ajog.2022.06.012. PubMed PMID: 35718110; PubMed Central PMCID: PMC9212257

Hill ME, Aliaga SR, Foglia EE. Learning with digital recording and video review of delivery room resuscitation. Semin Fetal Neonatal Med. 2022 Oct;27(5):101396. doi: 10.1016/j.siny.2022.101396. Epub 2022 Oct 18. PMID: 36457212.

Elsayed Y, Wahab MGA, Mohamed A, Fadel NB, Bhombal S, Yousef N, Fraga MV, Afifi J, Suryawanshi P, Hyderi A, Katheria A, Kluckow M, De Luca D, Singh Y. Point-of-care ultrasound (POCUS) protocol for systematic assessment of the crashing neonate-expert consensus statement of the international crashing neonate working group. Eur J Pediatr. 2022 Oct 14. doi: 10.1007/s00431-022-04636-z. Epub ahead of print. PMID: 36239816.

Foglia EE, Shah BA, Szyld E. Positive pressure ventilation at birth. Semin Perinatol. 2022 Oct;46(6):151623. doi: 10.1016/j.semperi.2022.151623. Epub 2022 May 21. PMID: 35697527.

Nitkin CR, Bamat NA, Lagatta J, DeMauro SB, Lee HC, Patel RM, King B, Slaughter JL, Campbell JP, Richardson T, Lewis T. Pulmonary Hypertension in Preterm Infants Treated With Laser vs Anti-Vascular Endothelial Growth Factor Therapy for Retinopathy of Prematurity. JAMA Ophthalmol. 2022 Nov 1;140(11):1085-1094. doi: 10.1001/jamaophthalmol.2022.3788. PubMed PMID: 36201183; PubMed Central PMCID: PMC9539731.

Wyckoff MH, Greif R, Morley PT, et al. 2022 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations: Summary From the Basic Life Support; Advanced Life Support; Pediatric Life Support; Neonatal Life Support; Education, Implementation, and Teams; and First Aid Task Forces. Circulation. 2022 Nov 3. doi: 10.1161/CIR.0000000000001095. Epub ahead of print. PMID: 36325905.

Ramadurai D, Salazar EG, Reddy A. “The Need to Address Social Determinants of Health During Critical Care Training.” ATS Scholar. 2022. Nov 15. DOI: 10.34197/ats-scholar.2022-0057VL.

Wild KT, Mathew L, Hedrick HL, Rintoul NE, Ades A, Soorikian L, Matthews K, Posencheg MA, Kesler E, Van Hoose KT, Panitch HB, Flibotte J, Foglia EE. Respiratory function after birth in infants with congenital diaphragmatic hernia. hernia. Arch Dis Child Fetal Neonatal Ed. 2022 Nov 18:fetalneonatal-2022-324415. doi: 10.1136/archdischild-2022-324415. Epub ahead of print. PMID: 36400455.

Flannery DD, Puopolo KM. The imperfect science of neonatal sepsis. Pediatr Res. Pediatr Res. 2022 Mar;91(4):733-734. doi: 10.1038/s41390-021-01863-2. Epub 2021 Nov 20. PubMed PMID: 34802037

Flannery DD, Puopolo KM, Hansen NI, Sánchez PJ, Stoll BJ; Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. Neonatal infections: Insights from a multicenter longitudinal research collaborative. Semin Perinatol. 2022 Nov;46(7):151637. doi: 10.1016/j.semperi.2022.151637. Epub 2022 Jun 10. PubMed PMID: 35864010

Montoya-Williams D, Gualy S, Mazur M, Huber M, Peña MM, DeMauro SB, Duncan AF. Impact of COVID-19 on Infants Followed After Discharge from the NICU Using a Telemedicine Model. American Journal of Perinatology. 2022 Nov 30.

Flannery DD, Puopolo KM. Neonatal Early-Onset Sepsis. Neoreviews, American Academy of Pediatrics. 2022 Nov 1;23(11):756-770. doi: 10.1542/neo.23-10-e756. PubMed PMID: 36316253

Myerson JW*, Patel PN*, Rubey KM*, et al. Supramolecular arrangement of protein in nanoparticle structures predicts nanoparticle tropism for neutrophils in acute lung inflammation. Nat Nanotechnol. 2022 Jan;17(1):86-97. doi: 10.1038/s41565-021-00997-y. Epub 2021 Nov 18. PubMed PMID: 34795440; PubMed Central PMCID: PMC8776575.

Stefanovski D, Tapia IE, Lioy J, Sengupta S, Mukhopadhyay S, Corcoran A, Cornaglia MA, Cielo CM. Respiratory indices during sleep in healthy infants: A prospective longitudinal study and meta-analysis. Sleep Med. 2022 Nov;99:49-57. doi: 10.1016/j.sleep.2022.07.010. Epub 2022 Jul 31. PMID: 35963199.

Rahde Bischoff A, Bhombal S, Altman CA, Fraga MV, Punn R, Rohatgi RK, Lopez L, McNamara PJ. Targeted Neonatal Echocardiography in Patients With Hemodynamic Instability. Pediatrics. 2022 Nov 1;150(Suppl 2):e2022056415I. doi: 10.1542/peds.2022-056415I. PMID: 36317979.

Jensen EA, DeMauro SB. Reduction in mechanical ventilation: Necessary but not sufficient to prevent bronchopulmonary dysplasia in extremely preterm infants? [Published online ahead of print Dec. 31, 2021] J Pediatr.

Stewart DL, Elsayed Y, Fraga MV, Coley BD, Annam A, Sarvis Milla S, AAP Committee on Fetus and Newborn and Section on Radiology. Technical Report: Use of Point-of-Care Ultrasonography in the NICU for Diagnostic and Procedural Purposes. Pediatrics. 2022 Dec 150;6:e2022060053.

Karavite D, Harris MC, Grundmeier RW, Srinivasan L, Shaeffer G, Muthu N: Using a Sociotechnical Model to Understand Challenges with Sepsis Recognition among Critically Ill Neonates. ACI Open 00: 1-15, 2022

Waller R, Kornfield SL, White LW, Chaiyachati BH, Barzilay R, Njoroge WF, Parish-Morris J, Duncan AF, Himes MM, Rodriguez Y, Seidlitz J, Riis V, Burris HH, Gur RE, Elovitz. Clinician-reported childbirth outcomes, patient-reported childbirth trauma, and risk for postpartum depression. Arch Womens Ment Health. 2022;25(5):985-993.

Maitre NL, Byrne R, Duncan A, et al. "High-risk for cerebral palsy" designation: A clinical consensus statement. Journal of Pediatric Rehabilitation Medicine. 2022 ;15(1):165-174. DOI: 10.3233/prm-220030. PMID: 35275579.

Kozyak BW, Fraga MV, Juliano CE, Bhombal S, Munson DA, Brandsma E, Stoller JZ, Jain A, Kesman R, Meshkati M, Noh CY, Dewitt AG, Costarino AT, Hehir DA, Groves AM: Real-time Ultrasound Guidance for Umbilical Venous Cannulation in Neonates with Congenital Heart Disease. Pediatric Critical Care Medicine 2022 Notes: Accepted.

Dyess N, Liberio B, Bernstein S, French H, Myers P. A National, Virtual Job Search Series for Neonatal-Perinatal Medicine Fellows. Journal of Graduate Medical Education, 2022; 14(3):337-338. PMID: 35754645.

Johnston L, Sawyer T, Nishisaki A, Whitfill T, Ades A, French H, Glass K, Dadiz R, Bruno C, Levit O, Auerbach M. Comparison of a Dichotomous versus Trichotomous Procedural Skills Checklist for Neonatal Intubation. BMC Medical Education, 2022; 22(1):645. PMID: 36028871.  

Gray MM, Dadiz R, Izatt S, Gillam-Kraukaer M, Carbajal MM, Johnston LC, Payne A, Vasquez MM, Bonachea EM, Karpen H, Falck AJ, Chess PR, Huber M, French H. Comparison of knowledge acquisition and retention following traditional didactic vs. flipped classroom education utilizing a standardized national curriculum: a randomized controlled trial. Journal of Perinatology, 2022; PMID 35660790.

Johnston L, Falck A, Vasquez M, Dadiz R, French H, Izatt S, Bonachea EM, Karpen H, Carbajal M, Payne A, Gillam-Krakauer M, Gray M. Flipping the Teachers: Impact of a Standardized Physiology Curriculum on Neonatology Medical Educators. American Journal of Perinatology, 2022; PMID: 36041469.

Mavis S, Caruso C, Carr CB, Dyess N, French H, Dadiz R, Vasquez M, Johnston L, Gillam-Krakauer M, Chess P, Izatt S, Payne A, Carabajal M, Bonchea E, Gray M. Consensus on an implicit bias and health disparities curriculum in neonatal medicine: a Delphi study. Journal of Perinatology, 2022; PMID 36203083.

Flannery DD, Edwards EM, Coggins SA, Horbar JD, Puopolo KM. Late-onset sepsis among very preterm infants. Pediatrics. 2022. doi: 10.1542/peds.2022-058813.

Rubey KM, et al. Nanoparticle-Induced Augmentation of Neutrophils' Phagocytosis of Bacteria. Front Pharmacol. 2022;13:923814. doi: 10.3389/fphar.2022.923814. eCollection 2022. PubMed PMID: 35860017; PubMed Central PMCID: PMC9289463.

Coggins SA, Glaser K. Updates in Late-Onset Sepsis: Risk Assessment, Therapy, and Outcomes. 2022. Neoreviews. 23(11): 738-755.

Flannery DD, Gouma S, Dhudasia MB, Mukhopadhyay S, Pfeifer MR, Woodford EC, Briker SM, Triebwasser JE, Gerber JS, Morris JS, Weirick ME, McAllister CM, Hensley SE, Puopolo KM. Comparison of Maternal and Neonatal Antibody Levels After COVID-19 Vaccination vs SARS-CoV-2 Infection. JAMA Netw Open. 2022;5(11):e2240993. PubMed PMID: 36350652.

Flannery DD, Edwards EM, Coggins SA, Horbar JD, Puopolo KM. Late-Onset Sepsis Among Very Preterm Infants. Pediatrics. 2022;150(6):e2022058813. PubMed PMID: 36366916.

Flannery, D.D., Zevallos Barboza, A., Pfeifer, M.R. et al. Perinatal COVID-19 maternal and neonatal outcomes at two academic birth hospitals. J Perinatol (2022). https://doi.org/10.1038/s41372-022-01446-x

Flannery DD, Mukhopadhyay S, Morales KH, Dhudasia MB, Passarella M, Gerber JS, Puopolo KM. Delivery Characteristics and the Risk of Early-Onset Neonatal Sepsis. Pediatrics. 2022;149(2):e2021052900. PubMed PMID: 35022750; PubMed Central PMCID: pending doi: 10.1542/peds.2021-052900. Online ahead of print.

Flannery DD, Chiotos K, Gerber JS, Puopolo KM. Neonatal multidrug resistant gram-negative infection: epidemiology, mechanisms of resistance, and management. Pediatr Res. 2022; 91(2):380-391.  PubMed PMID: 34599280; PubMed Central PMCID: PMC8819496

Flannery DD, Passarella M, Mukhopadhyay S, Dhudasia MB, Gerber JS, Lorch SA, Hennessy S, Puopolo KM. Early Childhood Antibiotic Utilization for Infants Discharged from the Neonatal Intensive Care Unit. J Perinatol. 2022. In press.

Burris HH, Mullin AM, Dhudasia MB, Flannery DD, Mukhopadhyay S, Pfeifer MR, Woodford EC, Briker SM, Triebwasser JE, Morris JS, Montoya-Williams D, Gouma S, Hensley SE, Puopolo KM. Neighborhood Characteristics and Racial Disparities in Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Seropositivity in Pregnancy. Obstet Gynecol. 2022. In press.

DeMauro SB, Burkhardt M, Wood A, Nilan K, Jensen EA, Bamat NA, Zhang H, Gibbs K. Early motor development in infants with moderate or severe bronchopulmonary dysplasia. J Neonatal Perinatal Med. 2022;15(1):55-62.

Bell EF, Hintz SR, Hansen NI, Bann CM, Wyckoff MH, DeMauro SB, Walsh MC, Vohr BR, Stoll BJ, Carlo WA, Van Meurs KP, Rysavy MA, Patel RM, Merhar SL, Sanchez PJ, Laptook AR, Hibbs AM, Cotten CM, D’Angio CT, Winter S, Fuller J, Das A; Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. Mortality, in-hospital morbidity, care practices, and 2-year outcomes for extremely preterm infants in the US, 2013-2018. JAMA. 2022;327(3):248-263.

Vyas-Read S, Logan JW, Cuna AC, Machry J, Leeman KT, Rose RS, Mikhael M, Wymore E, Ibrahim JW, DiGeronimo RJ, Yallapragada S, Haberman BE, Padula MA, Porta NF, Murthy K, Nelin LD, Coghill CH, Zaniletti I, Savani RC, Truog W, Engle WA, Lagatta JM. A comparison of newer classifications of bronchopulmonary dysplasia: findings from the Children’s Hospitals Neonatal Consortium Severe BPD Group. J Perinatol. 2022;42(1):58-64.

Lee CD, Nelin L, Foglia EE. Neonatal resuscitation in 22-week pregnancies. N Engl J Med. 2022;386(4):391-393.

Flannery DD, Akinboyo IC, Mukhopadhyay S, Tribble AC, Song L, Chen F, Li Y, Gerber JS, Puopolo, KM. Antibiotic Susceptibility of Escherichia coli Among Infants Admitted to Neonatal Intensive Care Units Across the US from 2009 to 2017. JAMA Pediatr. 2021 Feb 1;175(2):168-175. PubMed PMID: 33165599; PubMed Central PMCID: PMC7653538.

Garber SJ, Dhudasia MB, Flannery DD, Passarella MR, Puopolo KM, Mukhopadhyay S. Delivery-based criteria for empiric antibiotic administration among preterm infants. J Perinatol. 2021 Feb;41(2):255-262. PubMed PMID: 32792629; PubMed Central PMCID: PMC7881045.

Dhudasia MD, Flannery DD, Pfeifer MR, Puopolo KM. Updated Guidance: Prevention and Management of Perinatal Group B Streptococcus Infection. American Academy of Pediatrics NeoReviews 2021 Mar;22(3):e177-e188. PubMed PMID: 33649090.

Flannery DD, Puopolo KM. Perinatal COVID-19: guideline development, implementation, and challenges. Curr Opin Pediatr. 2021 Apr 1;33(2):188-194. PubMed PMID: 33534424. PMCID: PMC8048376

Flannery DD, Jensen EA, Tomlinson LA, Yu Y, Ying GS, Binenbaum G. Poor postnatal weight growth is a late finding after sepsis in very preterm infants. Arch Dis Child Fetal Neonatal Ed. 2021 May;106(3):298-304. PubMed PMID: 33148685; PubMed Central PMCID: PMC8291375.

Should Vitamin A Injections to Prevent Bronchopulmonary Dysplasia or Death Be Reserved for High-Risk Infants?: Reanalysis of the NICHD Neonatal Research Network Randomized Trial.  Rysavy MA, Li L, Tyson JE, Jensen EA, Das A, Ambalavanan N, Laughon MM, Greenberg RG, Patel RM, Pedroza C, Bell EF; Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. J Pediatr. 2021 May 15:S0022-3476(21)00445-5. doi: 10.1016/j.jpeds.2021.05.022. Online ahead of print. PMID: 34004189

Flannery DD, Gouma S, Dhudasia MB, Mukhopadhyay S, Pfeifer MR, Woodford EC, Triebwasser JE, Gerber JS, Morris JS, Weirick ME, McAllister CM, Bolton MJ, Arevalo CP, Anderson EM, Goodwin EC, Hensley SE, Puopolo KM. Assessment of Maternal and Neonatal Cord Blood SARS-CoV-2 Antibodies and Placental Transfer Ratios. JAMA Pediatr. 2021 Jun 1;175(6):594-600. PubMed PMID: 33512440; PubMed Central PMCID: PMC7846944.

Flannery DD, Wade KC. Immunization in the Neonatal Intensive Care Unit. Clin Perinatol. 2021 Jun;48(2):393-412. PubMed PMID: 34030821.

Variably methylated retrotransposons are refractory to a range of environmental perturbations. Bertozzi TM, Becker JL, Blake GET, Bansal A, Nguyen DK, Fernandez-Twinn DS, Ozanne SE, Bartolomei MS, Simmons RA, Watson ED, Ferguson-Smith AC. Nat Genet. 2021 Jul 29. doi: 10.1038/s41588-021-00898-9. Online ahead of print. PMID: 34326545

Human Placental Transcriptome Reveals Critical Alterations in Inflammation and Energy Metabolism with Fetal Sex Differences in Spontaneous Preterm Birth. Lien YC, Zhang Z, Cheng Y, Polyak E, Sillers L, Falk MJ, Ischiropoulos H, Parry S, Simmons RA.Int J Mol Sci. 2021 Jul 23;22(15):7899. doi: 10.3390/ijms22157899. PMID: 34360662 Free PMC article.

A multi-centre randomised controlled trial of respiratory function monitoring during stabilization of very preterm infants at birth. van Zanten HA, L A M Kuypers K, van Zwet EW, van Vonderen JJ, Omar F Kamlin C, Springer L, Lista G, Cavigioli F, Vento M, Núñez-Ramiro A, Oberthuer A, Kribs A, Kuester H, Horn S, Weinberg DD, Foglia EE, Morley CJ, Davis PG, Te Pas AB. Resuscitation. 2021 Jul 21:S0300-9572(21)00263-X. doi: 10.1016/j.resuscitation.2021.07.012. Online ahead of print. PMID: 34302924

A comparison of newer classifications of bronchopulmonary dysplasia: findings from the Children's Hospitals Neonatal Consortium Severe BPD Group. Vyas-Read S, Logan JW, Cuna AC, Machry J, Leeman KT, Rose RS, Mikhael M, Wymore E, Ibrahim JW, DiGeronimo RJ, Yallapragada S, Haberman BE, Padula MA, Porta NF, Murthy K, Nelin LD, Coghill CH, Zaniletti I, Savani RC, Truog W, Engle WA, Lagatta JM. J Perinatol. 2021 Aug 5:1-7. doi: 10.1038/s41372-021-01178-4. Online ahead of print. PMID: 34354227 Free PMC article.

Qualitative indications for tracheostomy and chronic mechanical ventilation in patients with severe bronchopulmonary dysplasia. Yallapragada S, Savani RC, Mūnoz-Blanco S, Lagatta JM, Truog WE, Porta NFM, Nelin LD, Zhang H, Vyas-Read S, DiGeronimo R, Natarajan G, Wymore E, Haberman B, Machry J, Potoka K; Children’s Hospital Neonatal Consortium severe bronchopulmonary dysplasia subgroup, Murthy K. J Perinatol. 2021 Aug 4:1-7. doi: 10.1038/s41372-021-01165-9. Online ahead of print. PMID: 34349231 Free PMC article.

Obesity-related IL-18 Impairs Treg Function and Promotes Lung Ischemia-reperfusion Injury. Akimova T, Zhang T, Christensen LM, Wang Z, Han R, Negorev D, Samanta A, Sasson IE, Gaddapara T, Jiao J, Wang L, Bhatti TR, Levine MH, Diamond JM, Beier UH, Simmons RA, Cantu E, Wilkes DS, Lederer DJ, Anderson M, Christie JD, Hancock WW. Am J Respir Crit Care Med. 2021 Aug 4. doi: 10.1164/rccm.202012-4306OC. Online ahead of print. PMID: 34346860

Assessment of Neonatal Intensive Care Unit Practices, Morbidity, and Mortality Among Very Preterm Infants in China. Cao Y, Jiang S, Sun J, Hei M, Wang L, Zhang H, Ma X, Wu H, Li X, Sun H, Zhou W, Shi Y, Wang Y, Gu X, Yang T, Lu Y, Du L, Chen C, Lee SK, Zhou W; Chinese Neonatal Network. JAMA Netw Open. 2021 Aug 2;4(8):e2118904. doi: 10.1001/jamanetworkopen.2021.18904. PMID: 34338792

Parental protective factors and stress in NICU mothers and fathers. Alina Ivashchuk et al. J Perinatol. 2021 Aug.

Nakhla D, Kushnir A, Ahmed R, Bhandari V, Hunter K, Nakhla T. Reticulocyte Count: The Forgotten Factor in Transfusion Decisions for Extremely Low Birth Weight Infants. Am J Perinatol. 2021 Sep 24. doi: 10.1055/a-1653-4585. Epub ahead of print. PMID: 34560784.

Flannery DD, Edwards EM, Puopolo KM, Horbar JH. Early-Onset Sepsis Among Very Preterm Infants. Pediatrics. 2021 Oct;148(4):e2021052456. PubMed PMID: 34493539; PubMed Central PMCID: pending

Montoya-Williams D, Mullin AM, Handley SC, Flannery DD, Lorch SA, Elovitz MA, Burris HH. Disparities in SARS-CoV-2 positivity among pregnant patients with limited English proficiency. J Perinatol. 2021 Oct;41(10):2564-2565.  PubMed PMID: 34497337; PubMed Central PMCID: PMC8425017.

Flannery DD, Puopolo KM. The imperfect science of neonatal sepsis. Pediatr Res. 2021 Nov 20. PubMed PMID: 34802037; doi: 10.1038/s41390-021-01863-2. Online ahead of print.

2021 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations: Summary From the Basic Life Support; Advanced Life Support; Neonatal Life Support; Education, Implementation, and Teams; First Aid Task Forces; and the COVID-19 Working Group. Wyckoff MH, Singletary EM, Soar J, Olasveengen TM, Greif R, Liley HG, Zideman D, Bhanji F, Andersen LW, Avis SR, Aziz K, Bendall JC, Berry DC, Borra V, Böttiger BW, Bradley R, Bray JE, Breckwoldt J, Carlson JN, Cassan P, Castrén M, Chang WT, Charlton NP, Cheng A, Chung SP, Considine J, Costa-Nobre DT, Couper K, Dainty KN, Davis PG, de Almeida MF, de Caen AR, de Paiva EF, Deakin CD, Djärv T, Douma MJ, Drennan IR, Duff JP, Eastwood KJ, Epstein JL, Escalante R, Fabres JG, Fawke J, Finn JC, Foglia EE, Folke F, Freeman K, Gilfoyle E, Goolsby CA, Grove A, Guinsburg R, Hatanaka T, Hazinski MF, Heriot GS, Hirsch KG, Holmberg MJ, Hosono S, Hsieh MJ, Hung KKC, Hsu CH, Ikeyama T, Isayama T, Kapadia VS, Kawakami M, Kim HS, Kloeck DA, Kudenchuk PJ, Lagina AT, Lauridsen KG, Lavonas EJ, Lockey AS, Malta Hansen C, Markenson D, Matsuyama T, McKinlay CJD, Mehrabian A, Merchant RM, Meyran D, Morley PT, Morrison LJ, Nation KJ, Nemeth M, Neumar RW, Nicholson T, Niermeyer S, Nikolaou N, Nishiyama C, O'Neil BJ, Orkin AM, Osemeke O, Parr MJ, Patocka C, Pellegrino JL, Perkins GD, Perlman JM, Rabi Y, Reynolds JC, Ristagno G, Roehr CC, Sakamoto T, Sandroni C, Sawyer T, Schmölzer GM, Schnaubelt S, Semeraro F, Skrifvars MB, Smith CM, Smyth MA, Soll RF, Sugiura T, Taylor-Phillips S, Trevisanuto D, Vaillancourt C, Wang TL, Weiner GM, Welsford M, Wigginton J, Wyllie JP, Yeung J, Nolan JP, Berg KM; Collaborators. Circulation. 2021 Nov 11:CIR0000000000001017. doi: 10.1161/CIR.0000000000001017. Online ahead of print. PMID: 34813356

Reduction in mechanical ventilation: Necessary but not sufficient to prevent bronchopulmonary dysplasia in extremely preterm infants? Jensen EA, DeMauro SB. J Pediatr. 2021 Dec 30:S0022-3476(21)01275-0. doi: 10.1016/j.jpeds.2021.12.068. Online ahead of print. PMID: 34974061 No abstract available.

Yallapragada S, Savani RC, Mūnoz-Blanco S, Lagatta JM, Truog WE, Porta NFM, Nelin LD, Zhang H, Vyas-Read S, DiGeronimo R, Natarajan G, Wymore E, Haberman B, Machry J, Potoka K; Children’s Hospital Neonatal Consortium severe bronchopulmonary dysplasia subgroup, Murthy K. Qualitative indications for tracheostomy and chronic mechanical ventilation in patients with severe bronchopulmonary dysplasia. J Perinatol. 2021;41(11):2651-2657.

Lien YC, Zhang Z, Cheng Y, Polyak E, Sillers L, Falk MJ, Ischiropoulos H, Parry S, Simmons RA. Human placental transcriptome reveals critical alterations in inflammation and energy metabolism with fetal sex differences in spontaneous preterm birth. Int J Mol Sci. 2021;22(15):7899.

Akimova T, Zhang T, Christensen LM, Wang Z, Han R, Negorev D, Samanta A, Sasson IE, Gaddapara T, Jiao J, Wang L, Bhatti TR, Levine MH, Diamond JM, Beier UH, Simmons RA, Cantu E, Wilkes DS, Lederer DJ, Anderson M, Christie JD, Hancock WW. Obesity-related IL-18 impairs T-regulatory cell function and promotes lung ischemia-reperfusion injury. Am J Respir Crit Care Med. 2021;204(9):1060-1074.

van Zanten HA, L A M Kuypers K, van Zwet EW, van Vonderen JJ, Omar F Kamlin C, Springer L, Lista G, Cavigioli F, Vento M, Núñez-Ramiro A, Oberthuer A, Kribs A, Kuester H, Horn S, Weinberg DD, Foglia EE, Morley CJ, Davis PG, Te Pas AB. A multi-centre randomised controlled trial of respiratory function monitoring during stabilization of very preterm infants at birth. Resuscitation. 2021;167:317-325.

Pawlowski TW, Stoller JZ, Rintoul NE, Hedrick HL, Quartermain MD, Fraga MV: Point-of-care Ultrasound for the Evaluation of Venous Cannula Position in Neonatal Extracorporeal Membrane Oxygenation. Journal of Perinatology 41(7): 1645-1650, 2021.

Stoller JZ, Fraga MV: Real-time ultrasound-guided lumbar puncture in the neonatal intensive care unit. Journal of Perinatology 41(10): 2495-2498, 2021.

Neonatal IL-4 exposure decreases adipogenesis of male rats into adulthood. Ying T, Golden TN, Cheng L, Ishibashi J, Seale P, Simmons RA. Am J Physiol Endocrinol Metab. 2021 Apr 19. doi: 10.1152/ajpendo.00600.2020. Online ahead of print. PMID: 33870712

Loop Diuretics in Severe Bronchopulmonary Dysplasia: Cumulative Use and Associations with Mortality and Age at Discharge. Bamat NA, Nelin TD, Eichenwald EC, Kirpalani H, Laughon MM, Jackson WM, Jensen EA, Gibbs KA, Lorch SA.J Pediatr. 2021 Apr;231:43-49.e3. doi: 10.1016/j.jpeds.2020.10.073. Epub 2020 Nov 3.PMID: 33152371

Access to risk-appropriate hospital care and disparities in neonatal outcomes in racial/ethnic groups and rural-urban populations. Lorch SA, Rogowski J, Profit J, Phibbs CS. Semin Perinatol. 2021 Mar 21:151409. doi: 10.1016/j.semperi.2021.151409. Online ahead of print. PMID: 33931237

Treatment of pulmonary hypertension during initial hospitalization in a multicenter cohort of infants with congenital diaphragmatic hernia (CDH). Seabrook RB, Grover TR, Rintoul N, Weems M, Keene S, Brozanski B, DiGeronimo R, Haberman B, Hedrick H, Gien J, Ali N, Chapman R, Daniel J, Harrison HA, Johnson Y, Porta NFM, Uhing M, Zaniletti I, Murthy K; Children’s Hospitals Neonatal Consortium Congenital Diaphragmatic Hernia Focus Group. J Perinatol. 2021 Mar 1. doi: 10.1038/s41372-021-00923-z. Online ahead of print. PMID: 33649432

Infants Born to Mothers With COVID-19-Making Room for Rooming-in. Kaufman DA, Puopolo KM.JAMA Pediatr. 2021 Mar 1;175(3):240-242. doi: 10.1001/jamapediatrics.2020.5100.PMID: 33284347 No abstract available.

Limitations of Conventional Magnetic Resonance Imaging as a Predictor of Death or Disability Following Neonatal Hypoxic-Ischemic Encephalopathy in the Late Hypothermia Trial. Laptook AR, Shankaran S, Barnes P, Rollins N, Do BT, Parikh NA, Hamrick S, Hintz SR, Tyson JE, Bell EF, Ambalavanan N, Goldberg RN, Pappas A, Huitema C, Pedroza C, Chaudhary AS, Hensman AM, Das A, Wyckoff M, Khan A, Walsh MC, Watterberg KL, Faix R, Truog W, Guillet R, Sokol GM, Poindexter BB, Higgins RD; Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. J Pediatr. 2021 Mar;230:106-111.e6. doi: 10.1016/j.jpeds.2020.11.015. Epub 2020 Nov 13.PMID: 33189747

Neurodevelopmental and Growth Outcomes of Extremely Preterm Infants with Short Bowel Syndrome. Bell M, Cole CR, Hansen NI, Duncan AF, Hintz SR, Adams-Chapman I; Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. J Pediatr. 2021 Mar;230:76-83.e5. doi: 10.1016/j.jpeds.2020.11.026. Epub 2020 Nov 24.PMID: 33246015

Mouse models of growth hormone deficiency. List EO, Basu R, Duran-Ortiz S, Krejsa J, Jensen EA.Rev Endocr Metab Disord. 2021 Mar;22(1):3-16. doi: 10.1007/s11154-020-09601-5. Epub 2020 Oct 9.PMID: 33033978 Review.

Neonatal resuscitation research: closing the gap. Te Pas A, Roehr CC, Foglia EE, Hooper S. Pediatr Res. 2021 Feb 24. doi: 10.1038/s41390-021-01403-y. Online ahead of print. PMID: 33627819 No abstract available.

The Role of Adipocyte Precursors in Development and Obesity. Ying T, Simmons RA.Front Endocrinol (Lausanne). 2021 Feb 19;11:613606. doi: 10.3389/fendo.2020.613606. eCollection 2020.PMID: 33679601 Free PMC article. Review.

Central Line Utilization and Complications in Infants with Congenital Diaphragmatic Hernia. Grover TR, Weems MF, Brozanski B, Daniel J, Haberman B, Rintoul N, Walden A, Hedrick H, Mahmood B, Seabrook R, Murthy K, Zaniletti I, Keene S; Children's Hospitals Neonatal Consortium (CHNC) Congenital Diaphragmatic Hernia Focus Group. Am J Perinatol. 2021 Feb 3. doi: 10.1055/s-0041-1722941. Online ahead of print. PMID: 33535242

Balancing Risks in the Time of COVID-19. Kimberlin DW, Puopolo KM.JAMA Pediatr. 2021 Feb 1;175(2):129-130. doi: 10.1001/jamapediatrics.2020.4304.PMID: 33044485 No abstract available.

Antibiotic Susceptibility of Escherichia coli Among Infants Admitted to Neonatal Intensive Care Units Across the US From 2009 to 2017. Flannery DD, Akinboyo IC, Mukhopadhyay S, Tribble AC, Song L, Chen F, Li Y, Gerber JS, Puopolo KM.JAMA Pediatr. 2021 Feb 1;175(2):168-175. doi: 10.1001/jamapediatrics.2020.4719.PMID: 33165599 Free PMC article.

Reply. Foglia EE, Carper B, Gantz M, Schmidt B.J Pediatr. 2021 Feb;229:311. doi: 10.1016/j.jpeds.2020.11.006. Epub 2020 Nov 9.PMID: 33181196 No abstract available.

Delivery-based criteria for empiric antibiotic administration among preterm infants. Garber SJ, Dhudasia MB, Flannery DD, Passarella MR, Puopolo KM, Mukhopadhyay S.J Perinatol. 2021 Feb;41(2):255-262. doi: 10.1038/s41372-020-00784-y. Epub 2020 Aug 13.PMID: 32792629 Free PMC article.

Cost of clinician-driven tests and treatments in very low birth weight and/or very preterm infants. King BC, Richardson T, Patel RM, Lee HC, Bamat NA, Patrick SW, Gautham KS, Hall M, Slaughter JL.J Perinatol. 2021 Feb;41(2):295-304. doi: 10.1038/s41372-020-00879-6. Epub 2020 Dec 2.PMID: 33268831

Survival and Developmental Outcomes of Neonates Treated with Extracorporeal Membrane Oxygenation: A 10-Year Single-Center Experience. Kim F, Bernbaum J, Connelly J, Gerdes M, Hedrick HL, Hoffman C, Rintoul NE, Ziolkowski K, DeMauro SB. J Pediatr. 2021 Feb;229:134-140.e3. doi: 10.1016/j.jpeds.2020.10.011. Epub 2020 Oct 13.PMID: 33058857

Racial/ethnic differences in maternal resilience and associations with low birthweight. Montoya-Williams D, Passarella M, Grobman WA, Lorch SA.J Perinatol. 2021 Feb;41(2):196-203. doi: 10.1038/s41372-020-00837-2. Epub 2020 Oct 7.PMID: 33028937

Preserved pressure delivery during high-frequency oscillation of bubble CPAP in a premature infant lung model with both normal and abnormal lung mechanics.  Sivieri EM, Rub DM, Abbasi S, Eichenwald EC. Pediatr Pulmonol. 2021 Jan 26. doi: 10.1002/ppul.25267. Online ahead of print. PMID: 33497536.

Neurodevelopmental outcomes following neonatal late-onset sepsis and blood culture-negative conditions.  Mukhopadhyay S, Puopolo KM, Hansen NI, Lorch SA, DeMauro SB, Greenberg RG, Cotten CM, Sanchez PJ, Bell EF, Eichenwald EC, Stoll BJ; NICHD Neonatal Research Network. Arch Dis Child Fetal Neonatal Ed. 2021 Jan 21:fetalneonatal-2020-320664. doi: 10.1136/archdischild-2020-320664. Online ahead of print. PMID: 33478957.

Associations between family presence and neonatal intubation outcomes: a report from the National Emergency Airway Registry for Neonates: NEAR4NEOS. Brei BK, Sawyer T, Umoren R, Gray MM, Krick J, Foglia EE, Ades A, Glass K, Kim JH, Singh N, Jung P, Johnston L, Moussa A, Napolitano N, Barry J, Zenge J, Quek B, DeMeo SD, Shults J, Unrau J, Nadkarni V, Nishisaki A; National Emergency Airway Registry for Neonates (NEAR4NEOS) investigators. Arch Dis Child Fetal Neonatal Ed. 2021 Jan 21:fetalneonatal-2020-319709. doi: 10.1136/archdischild-2020-319709. Online ahead of print. PMID: 33478956

Black-White disparities in maternal in-hospital mortality according to teaching and Black-serving hospital status. Burris HH, Passarella M, Handley SC, Srinivas SK, Lorch SA. Am J Obstet Gynecol. 2021 Jan 13:S0002-9378(21)00027-2. doi: 10.1016/j.ajog.2021.01.004. Online ahead of print. PMID: 33453183

Umbilical Cord Milking vs Delayed Cord Clamping and Associations with In-Hospital Outcomes among Extremely Premature Infants. Kumbhat N, Eggleston B, Davis AS, DeMauro SB, Van Meurs KP, Foglia EE, Lakshminrusimha S, Walsh MC, Watterberg KL, Wyckoff MH, Das A, Handley SC; Generic Database Subcommittee of the National Institute of Child Health and Human Development Neonatal Research Network. J Pediatr. 2021 Jan 5:S0022-3476(20)31582-1. doi: 10.1016/j.jpeds.2020.12.072. Online ahead of print. PMID: 33417919

Rethinking How to Persuade More Parents From Diverse or Disadvantaged Backgrounds to Enroll Infants in Neonatal Clinical Trials. Burris HH, Duncan AF.JAMA Netw Open. 2021 Jan 4;4(1):e2032137. doi: 10.1001/jamanetworkopen.2020.32137.PMID: 33433592 Free article. No abstract available.

The effect of dietary nitrate on exercise capacity in chronic kidney disease: a randomized controlled pilot study. Ramick MG, Kirkman DL, Stock JM, Muth BJ, Farquhar WB, Chirinos JA, Doulias PT, Ischiropoulos H, Edwards DG.Nitric Oxide. 2021 Jan 1;106:17-23. doi: 10.1016/j.niox.2020.10.002. Epub 2020 Oct 17.PMID: 33080411

Neonatal delivery room CPR: An analysis of the Get with the Guidelines®-Resuscitation Registry. Halling C, Raymond T, Brown LS, Ades A, Foglia EE, Allen E, Wyckoff MH; American Heart Association’s Get With The Guidelines–Resuscitation Investigators. Resuscitation. 2021 Jan;158:236-242. doi: 10.1016/j.resuscitation.2020.10.007. Epub 2020 Oct 17.PMID: 33080368

Maternal psychosocial functioning, obstetric health history, and newborn telomere length. Bosquet Enlow M, Petty CR, Hacker MR, Burris HH. Psychoneuroendocrinology. 2021 Jan;123:105043. doi: 10.1016/j.psyneuen.2020.105043. Epub 2020 Nov 4.PMID: 33176222

Development and evaluation of MADDIE: Method to Acquire Delivery Date Information from Electronic health records. Canelón SP, Burris HH, Levine LD, Boland MR.Int J Med Inform. 2021 Jan;145:104339. doi: 10.1016/j.ijmedinf.2020.104339. Epub 2020 Nov 6.PMID: 33232918 Free article.

It Is Time to ACT NOW to Improve Quality for Opioid-Exposed Infants. Patrick SW, Lorch SA.Pediatrics. 2021 Jan;147(1):e2020028340. doi: 10.1542/peds.2020-028340. Epub 2020 Dec 21.PMID: 33386340 No abstract available.

New Strategies to Tackle the Combined Biological and Social Context of Preterm Birth. Montoya-Williams D, Salloum RG, Lorch SA.Am J Perinatol. 2021 Jan;38(2):202-204. doi: 10.1055/s-0039-1695774. Epub 2019 Sep 3.PMID: 31480082

Higher or Lower Hemoglobin Transfusion Thresholds for Preterm Infants. Kirpalani H, Bell EF, Hintz SR, Tan S, Schmidt B, Chaudhary AS, Johnson KJ, Crawford MM, Newman JE, Vohr BR, Carlo WA, D'Angio CT, Kennedy KA, Ohls RK, Poindexter BB, Schibler K, Whyte RK, Widness JA, Zupancic JAF, Wyckoff MH, Truog WE, Walsh MC, Chock VY, Laptook AR, Sokol GM, Yoder BA, Patel RM, Cotten CM, Carmen MF, Devaskar U, Chawla S, Seabrook R, Higgins RD, Das A; Eunice Kennedy Shriver NICHD Neonatal Research Network.N Engl J Med. 2020 Dec 31;383(27):2639-2651. doi: 10.1056/NEJMoa2020248.PMID: 33382931 Clinical Trial.

Retrospective development of a novel resilience indicator using existing cohort data: The adolescent to adult health resilience instrument. Montoya-Williams D, Passarella M, Lorch SA. PLoS One. 2020 Dec 10;15(12):e0243564. doi: 10.1371/journal.pone.0243564. eCollection 2020.PMID: 33301500 Free PMC article.

Changes in Preterm Birth Phenotypes and Stillbirth at 2 Philadelphia Hospitals During the SARS-CoV-2 Pandemic, March-June 2020 . Handley SC, Mullin AM, Elovitz MA, Gerson KD, Montoya-Williams D, Lorch SA, Burris HH. JAMA. 2020 Dec 7. doi: 10.1001/jama.2020.20991. Online ahead of print. PMID: 33284323 No abstract available.

Racial and ethnic representation in epigenomic studies of preterm birth: a systematic review. Collier AY, Ledyard R, Montoya-Williams D, Qiu M, Dereix AE, Farrokhi MR, Hacker MR, Burris HH. Epigenomics. 2020 Dec 2. doi: 10.2217/epi-2020-0007. Online ahead of print. PMID: 33264049

Transcriptomic and Quantitative Proteomic Profiling Reveals Signaling Pathways Critical for Pancreatic Islet Maturation. Lien YC, Won KJ, Simmons RA.Endocrinology. 2020 Dec 1;161(12):bqaa187. doi: 10.1210/endocr/bqaa187.PMID: 33053583

Team Stress and Adverse Events during Neonatal Tracheal Intubations: A Report from NEAR4NEOS. Umoren RA, Sawyer TL, Ades A, DeMeo S, Foglia EE, Glass K, Gray MM, Barry J, Johnston L, Jung P, Kim JH, Krick J, Moussa A, Mulvey C, Nadkarni V, Napolitano N, Quek BH, Singh N, Zenge JP, Shults J, Nishisaki A; National Emergency Airway Registry for Neonates (NEAR4NEOS) Investigators.Am J Perinatol. 2020 Dec;37(14):1417-1424. doi: 10.1055/s-0039-1693698. Epub 2019 Jul 31.PMID: 31365934

Glucose concentrations in enterally fed preterm infants. Barrero-Castillero A, Mao W, Stark AR, Miedema D, Pursley DM, Burris HH. J Perinatol. 2020 Dec;40(12):1834-1840. doi: 10.1038/s41372-020-0754-6. Epub 2020 Aug 5.PMID: 32759957

What is bronchopulmonary dysplasia and does caffeine prevent it? Jensen EA. Semin Fetal Neonatal Med. 2020 Dec;25(6):101176. doi: 10.1016/j.siny.2020.101176. Epub 2020 Nov 2.PMID: 33168465 Review.

Antibiotic stewardship in neonates and in neonatal intensive care units. Mukhopadhyay S. Semin Perinatol. 2020 Dec;44(8):151321. doi: 10.1016/j.semperi.2020.151321. Epub 2020 Oct 13.PMID: 33158601

Role of microbiological tests and biomarkers in antibiotic stewardship. Rub DM, Dhudasia MB, Healy T, Mukhopadhyay S. Semin Perinatol. 2020 Dec;44(8):151328. doi: 10.1016/j.semperi.2020.151328. Epub 2020 Oct 12.PMID: 33158600

Antibiotic stewardship for early-onset sepsis. Kuzniewicz MW, Puopolo KM. Semin Perinatol. 2020 Dec;44(8):151325. doi: 10.1016/j.semperi.2020.151325. Epub 2020 Oct 12.PMID: 33221072

National and international guidelines for neonatal caffeine use: Are they evidenced-based? Eichenwald EC. Semin Fetal Neonatal Med. 2020 Dec;25(6):101177. doi: 10.1016/j.siny.2020.101177. Epub 2020 Nov 4.PMID: 33214064 Review.

Pediatric research priorities in healthcare-associated infections and antimicrobial stewardship. Coffin SE, Abanyie F, Bryant K, Cantey J, Fiore A, Fritz S, Guzman-Cottrill J, Hersh AL, Huskins WC, Kociolek LK, Kronman M, Lautenbach E, Lee G, Linam M, Logan LK, Milstone A, Newland J, Nyquist AC, Palazzi DL, Patel S, Puopolo K, Reddy SC, Saiman L, Sandora T, Shane AL, Smith M, Tamma PD, Zaoutis T, Zerr D, Gerber JS; CDC Prevention Epicenters Program.Infect Control Hosp Epidemiol. 2020 Nov 26:1-4. doi: 10.1017/ice.2020.1267. Online ahead of print. PMID: 33239122

Maternal anxiety and depression in pregnancy and DNA methylation of the NR3C1 glucocorticoid receptor gene. Dereix AE, Ledyard R, Redhunt AM, Bloomquist TR, Brennan KJ, Baccarelli AA, Hacker MR, Burris HH. Epigenomics. 2020 Nov 20. doi: 10.2217/epi-2020-0022. Online ahead of print. PMID: 33215541

Predictive Value of the BSID-II and the Bayley-III for Early School Age Cognitive Function in Very Preterm Infants. Flynn RS, Huber MD, DeMauro SB.Glob Pediatr Health. 2020 Nov 20;7:2333794X20973146. doi: 10.1177/2333794X20973146. eCollection 2020.PMID: 33283025 Free PMC article.

Environmental and Aerosolized Severe Acute Respiratory Syndrome Coronavirus 2 Among Hospitalized Coronavirus Disease 2019 Patients. Binder RA, Alarja NA, Robie ER, Kochek KE, Xiu L, Rocha-Melogno L, Abdelgadir A, Goli SV, Farrell AS, Coleman KK, Turner AL, Lautredou CC, Lednicky JA, Lee MJ, Polage CR, Simmons RA, Deshusses MA, Anderson BD, Gray GC.J Infect Dis. 2020 Nov 9;222(11):1798-1806. doi: 10.1093/infdis/jiaa575.PMID: 32905595 Free PMC article.

Intrauterine Inflammation Alters the Transcriptome and Metabolome in Placenta. Lien YC, Zhang Z, Barila G, Green-Brown A, Elovitz MA, Simmons RA.Front Physiol. 2020 Nov 5;11:592689. doi: 10.3389/fphys.2020.592689. eCollection 2020.PMID: 33250783 Free PMC article.

Poor postnatal weight growth is a late finding after sepsis in very preterm infants. Flannery DD, Jensen EA, Tomlinson LA, Yu Y, Ying GS, Binenbaum G; Postnatal Growth and ROP (G-ROP) Study Group.Arch Dis Child Fetal Neonatal Ed. 2020 Nov 4:fetalneonatal-2020-320221. doi: 10.1136/archdischild-2020-320221. Online ahead of print. PMID: 33148685

Systematic elucidation of neuron-astrocyte interaction in models of amyotrophic lateral sclerosis using multi-modal integrated bioinformatics workflow. Mishra V, Re DB, Le Verche V, Alvarez MJ, Vasciaveo A, Jacquier A, Doulias PT, Greco TM, Nizzardo M, Papadimitriou D, Nagata T, Rinchetti P, Perez-Torres EJ, Politi KA, Ikiz B, Clare K, Than ME, Corti S, Ischiropoulos H, Lotti F, Califano A, Przedborski S.Nat Commun. 2020 Nov 4;11(1):5579. doi: 10.1038/s41467-020-19177-y.PMID: 33149111 Free PMC article.

AMPA Receptor Surface Expression Is Regulated by S-Nitrosylation of Thorase and Transnitrosylation of NSF. Umanah GKE, Ghasemi M, Yin X, Chang M, Kim JW, Zhang J, Ma E, Scarffe LA, Lee YI, Chen R, Tangella K, McNamara A, Abalde-Atristain L, Dar MA, Bennett S, Cortes M, Andrabi SA, Doulias PT, Ischiropoulos H, Dawson TM, Dawson VL.Cell Rep. 2020 Nov 3;33(5):108329. doi: 10.1016/j.celrep.2020.108329.PMID: 33147468 Free PMC article.

Neonatal Opioid Withdrawal Syndrome. Patrick SW, Barfield WD, Poindexter BB; COMMITTEE ON FETUS AND NEWBORN, COMMITTEE ON SUBSTANCE USE AND PREVENTION.Pediatrics. 2020 Nov;146(5):e2020029074. doi: 10.1542/peds.2020-029074.PMID: 33106341 Review.

Neonatal intestinal dysbiosis. Underwood MA, Mukhopadhyay S, Lakshminrusimha S, Bevins CL. J Perinatol. 2020 Nov;40(11):1597-1608. doi: 10.1038/s41372-020-00829-2. Epub 2020 Sep 23.PMID: 32968220 Free PMC article.

Corrective steps to enhance ventilation in the delivery room. Yang KC, Te Pas AB, Weinberg DD, Foglia EE.Arch Dis Child Fetal Neonatal Ed. 2020 Nov;105(6):605-608. doi: 10.1136/archdischild-2019-318579. Epub 2020 Mar 9.PMID: 32152191

Neonatal Life Support 2020 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations. Wyckoff MH, Wyllie J, Aziz K, de Almeida MF, Fabres JW, Fawke J, Guinsburg R, Hosono S, Isayama T, Kapadia VS, Kim HS, Liley HG, McKinlay CJD, Mildenhall L, Perlman JM, Rabi Y, Roehr CC, Schmölzer GM, Szyld E, Trevisanuto D, Velaphi S, Weiner GM; Neonatal Life Support Collaborators. Resuscitation. 2020 Nov;156:A156-A187. doi: 10.1016/j.resuscitation.2020.09.015. Epub 2020 Oct 21.PMID: 33098917

Carbon dioxide clearance using bubble CPAP with superimposed high-frequency oscillations in a premature infant lung model with abnormal lung mechanics. Sivieri EM, Eichenwald EC, Rub D, Abbasi S. Pediatr Pulmonol. 2020 Nov;55(11):3189-3196. doi: 10.1002/ppul.25040. Epub 2020 Sep 2.PMID: 32841540

Routine Neuroimaging of the Preterm Brain. Hand IL, Shellhaas RA, Milla SS; COMMITTEE ON FETUS AND NEWBORN, SECTION ON NEUROLOGY, SECTION ON RADIOLOGY.Pediatrics. 2020 Nov;146(5):e2020029082. doi: 10.1542/peds.2020-029082.PMID: 33106343

Differential gene signature in adipose tissue depots of growth hormone transgenic mice. Duran-Ortiz S, Young JA, Jara A, Jensen EA, Basu R, List EO, Qian Y, Kopchick JJ, Berryman DE .J Neuroendocrinol. 2020 Nov;32(11):e12893. doi: 10.1111/jne.12893. Epub 2020 Oct 12.PMID: 33043505

The Disproportionate Burden of the COVID-19 Pandemic Among Pregnant Black Women. Gur RE, White LK, Waller R, Barzilay R, Moore TM, Kornfield S, Njoroge WFM, Duncan AF, Chaiyachati BH, Parish-Morris J, Maayan L, Himes MM, Laney N, Simonette K, Riis V, Elovitz MA.Psychiatry Res. 2020 Nov;293:113475. doi: 10.1016/j.psychres.2020.113475. Epub 2020 Sep 24.PMID: 33007683 Free PMC article.

Paternal bisphenol A exposure in mice impairs glucose tolerance in female offspring. Rashid CS, Bansal A, Mesaros C, Bartolomei MS, Simmons RA.Food Chem Toxicol. 2020 Nov;145:111716. doi: 10.1016/j.fct.2020.111716. Epub 2020 Sep 3.PMID: 32890688

Subsidize the test, the treatment or both? Results of an individually randomised controlled trial of the management of suspected malaria fevers in the retail sector in western Kenya. Laktabai J, Saran I, Zhou Y, Simmons RA, Turner EL, Visser T, O'Meara W.BMJ Glob Health. 2020 Nov;5(11):e003378. doi: 10.1136/bmjgh-2020-003378.PMID: 33148541 Free PMC article.

Surface mining and low birth weight in central Appalachia. Small DS, Firth DW, Keele LJ, Huber M, Passarella M, Lorch SA, Burris HH. Environ Res. 2020 Oct 22:110340. doi: 10.1016/j.envres.2020.110340. Online ahead of print. PMID: 33098818

Neonatal Life Support: 2020 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations. Wyckoff MH, Wyllie J, Aziz K, de Almeida MF, Fabres J, Fawke J, Guinsburg R, Hosono S, Isayama T, Kapadia VS, Kim HS, Liley HG, McKinlay CJD, Mildenhall L, Perlman JM, Rabi Y, Roehr CC, Schmölzer GM, Szyld E, Trevisanuto D, Velaphi S, Weiner GM; Neonatal Life Support Collaborators. Circulation. 2020 Oct 20;142(16_suppl_1):S185-S221. doi: 10.1161/CIR.0000000000000895. Epub 2020 Oct 21.PMID: 33084392

Withholding or withdrawing life-sustaining treatment in extremely low gestational age neonates. Dworetz AR, Natarajan G, Langer J, Kinlaw K, James JR, Bidegain M, Das A, Poindexter B, Bell EF, Cotten CM, Kirpalani H, Shankaran S, Stoll BJ; Eunice Kennedy Shriver National Institute of Child Health; Human Development Neonatal Research Network.Arch Dis Child Fetal Neonatal Ed. 2020 Oct 20:fetalneonatal-2020-318855. doi: 10.1136/archdischild-2020-318855. Online ahead of print. PMID: 33082153

Effect of a Nonoptimal Cervicovaginal Microbiota and Psychosocial Stress on Recurrent Spontaneous Preterm Birth. Gerson KD, Mccarthy C, Ravel J, Elovitz MA, Burris HH.Am J Perinatol. 2020 Oct 8. doi: 10.1055/s-0040-1717098. Online ahead of print. PMID: 33032329

Supratherapeutic rivaroxaban levels: A persistent drug-drug interaction after discontinuation of amiodarone. Skov K, Falskov B, Jensen EA, Dorff MH.Basic Clin Pharmacol Toxicol. 2020 Oct;127(4):351-353. doi: 10.1111/bcpt.13419. Epub 2020 May 4.PMID: 32336024

The impact of paid family leave in the United States on birth outcomes and mortality in the first year of life. Montoya-Williams D, Passarella M, Lorch SA.Health Serv Res. 2020 Oct;55 Suppl 2(Suppl 2):807-814. doi: 10.1111/1475-6773.13288. Epub 2020 Apr 5.PMID: 32249413 Free PMC article.

STAT3-BDNF-TrkB signalling promotes alveolar epithelial regeneration after lung injury. Paris AJ, Hayer KE, Oved JH, Avgousti DC, Toulmin SA, Zepp JA, Zacharias WJ, Katzen JB, Basil MC, Kremp MM, Slamowitz AR, Jayachandran S, Sivakumar A, Dai N, Wang P, Frank DB, Eisenlohr LC, Cantu E 3rd, Beers MF, Weitzman MD, Morrisey EE, Worthen GS.Nat Cell Biol. 2020 Oct;22(10):1197-1210. doi: 10.1038/s41556-020-0569-x. Epub 2020 Sep 28.PMID: 32989251

Protocol adherence rates in superiority and non-inferiority randomized clinical trials published in high impact medical journals. Bamat NA, Ekhaguere OA, Zhang L, Flannery DD, Handley SC, Herrick HM, Ellenberg SS. Clin Trials. 2020 Oct;17(5):552-559. doi: 10.1177/1740774520941428. Epub 2020 Jul 15.PMID: 32666826 Free PMC article.

Hand Function at 18-22 Months Is Associated with School-Age Manual Dexterity and Motor Performance in Children Born Extremely Preterm. Duncan AF, Bann CM, Maitre NL, Peralta-Carcelen M, Hintz SR; Eunice Kennedy Shriver National Institute of Child Health and Development Neonatal Research Network. J Pediatr. 2020 Oct;225:51-57.e3. doi: 10.1016/j.jpeds.2020.05.048. Epub 2020 May 28.PMID: 32474029

Racial and Ethnic Disparities in the Delayed Diagnosis of Appendicitis Among Children. Goyal MK, Chamberlain JM, Webb M, Grundmeier RW, Johnson TJ, Lorch SA, Zorc JJ, Alessandrini E, Bajaj L, Cook L, Alpern ER; Pediatric Emergency Care Applied Research Network (PECARN).Acad Emerg Med. 2020 Sep 29. doi: 10.1111/acem.14142. Online ahead of print. PMID: 32991770

Cerebral Pulsed Arterial Spin Labeling Perfusion Weighted Imaging Predicts Language and Motor Outcomes in Neonatal Hypoxic-Ischemic Encephalopathy. Zheng Q, Martin-Saavedra JS, Saade-Lemus S, Vossough A, Zuccoli G, Gonçalves FG, Freeman CW, Ouyang M, Singh V, Padula MA, Demauro SB, Flibotte J, Eichenwald EC, Detre JA, Sze RW, Huang H, Hwang M.Front Pediatr. 2020 Sep 25;8:576489. doi: 10.3389/fped.2020.576489. eCollection 2020.PMID: 33102411 Free PMC article.

Statistical properties of Continuous Composite Outcomes: Implications for clinical trial design. Troy JD, Simmons RA. Contemp Clin Trials Commun. 2020 Sep 24;20:100655. doi: 10.1016/j.conctc.2020.100655. eCollection 2020 Dec.PMID: 33024883 Free PMC article.

Locations of Mass Shootings Relative to Schools and Places Frequented by Children. Nance ML, DeSimone JD, Lorch SA, Passarella M, Cronin KM, Kreinces J, Myers SR.JAMA Pediatr. 2020 Sep 8;174(11):1109-10. doi: 10.1001/jamapediatrics.2020.3371. Online ahead of print. PMID: 32897315

Duration of Resuscitation at Birth, Mortality, and Neurodevelopment: A Systematic Review. Foglia EE, Weiner G, de Almeida MFB, Wyllie J, Wyckoff MH, Rabi Y, Guinsburg R; INTERNATIONAL LIAISON COMMITTEE ON RESUSCITATION NEONATAL LIFE SUPPORT TASK FORCE.Pediatrics. 2020 Sep;146(3):e20201449. doi: 10.1542/peds.2020-1449. Epub 2020 Aug 12.PMID: 32788267

Clinical impact of neonatal hypoglycemia screening in the well-baby care. Mukhopadhyay S, Wade KC, Dhudasia MB, Skerritt L, Chou JH, Dukhovny D, Puopolo KM.J Perinatol. 2020 Sep;40(9):1331-1338. doi: 10.1038/s41372-020-0641-1. Epub 2020 Mar 9.PMID: 32152490 Free PMC article.

Resuscitation before cord clamping: the maternal experience. Guttmann K, Martin A, Chaudhary A, Cole J, Foglia EE.Arch Dis Child Fetal Neonatal Ed. 2020 Sep;105(5):569-570. doi: 10.1136/archdischild-2019-318190. Epub 2019 Dec 5.PMID: 31806665 No abstract available.

Strategies for Evaluating Telehealth. Chuo J, Macy ML, Lorch SA.Pediatrics. 2020 Nov;146(5):e20201781. doi: 10.1542/peds.2020-1781. Epub 2020 Aug 18.PMID: 32817398 Free PMC article. No abstract available.

Resilience During Pregnancy by Race, Ethnicity and Nativity: Evidence of a Hispanic Immigrant Advantage. Montoya-Williams D, Ledyard R, Hacker MR, Burris HH. J Racial Ethn Health Disparities. 2020 Aug 17:10.1007/s40615-020-00847-y. doi: 10.1007/s40615-020-00847-y. Online ahead of print. PMID: 32808195

Recorded Flexible Nasolaryngoscopy for Neonatal Vocal Cord Assessment in a Prospective Cohort . Chorney SR, Zur KB, Buzi A, McKenna Benoit MK, Chennupati SK, Kleinman S, DeMauro SB, Elden LM. Ann Otol Rhinol Laryngol. 2020 Aug 14:3489420950370. doi: 10.1177/0003489420950370. Online ahead of print. PMID: 32795099

Neighborhood Violent Crime and Perceived Stress in Pregnancy. Shannon MM, Clougherty JE, McCarthy C, Elovitz MA, Nguemeni Tiako MJ, Melly SJ, Burris HH.Int J Environ Res Public Health. 2020 Aug 3;17(15):5585. doi: 10.3390/ijerph17155585.PMID: 32756321

The Effects of 20-kDa Human Placental GH in Male and Female GH-deficient Mice: An Improved Human GH? List EO, Berryman DE, Basu R, Buchman M, Funk K, Kulkarni P, Duran-Ortiz S, Qian Y, Jensen EA, Young JA, Yildirim G, Yakar S, Kopchick JJ.Endocrinology. 2020 Aug 1;161(8):bqaa097. doi: 10.1210/endocr/bqaa097.PMID: 32556100

Maternal and neonatal response to COVID-19. Golden TN, Simmons RA.Am J Physiol Endocrinol Metab. 2020 Aug 1;319(2):E315-E319. doi: 10.1152/ajpendo.00287.2020. Epub 2020 Jun 23.PMID: 32574110 Free PMC article.

Outcomes associated with surfactant in more mature and larger premature infants with respiratory distress syndrome. Jackson W, Taylor G, Bamat NA, Zimmerman K, Clark R, Benjamin DK, Laughon MM, Greenberg RG, Hornik CP.J Perinatol. 2020 Aug;40(8):1171-1177. doi: 10.1038/s41372-020-0625-1. Epub 2020 Feb 20.PMID: 32080333

Recorded Continuous Oximetry Improves Postdischarge Management of Bronchopulmonary Dysplasia. DeMauro SB.Pediatrics. 2020 Aug;146(2):e2020002774. doi: 10.1542/peds.2020-002774. Epub 2020 Jul 14.PMID: 32665371 No abstract available.

A multiple baseline study of a brief alcohol reduction and family engagement intervention for fathers in Kenya. Giusto A, Green EP, Simmons RA, Ayuku D, Patel P, Puffer ES.J Consult Clin Psychol. 2020 Aug;88(8):708-725. doi: 10.1037/ccp0000559.PMID: 32700954

Crosstalk between the growth hormone/insulin-like growth factor-1 axis and the gut microbiome: A new frontier for microbial endocrinology. Jensen EA, Young JA, Mathes SC, List EO, Carroll RK, Kuhn J, Onusko M, Kopchick JJ, Murphy ER, Berryman DE.Growth Horm IGF Res. 2020 Aug-Oct;53-54:101333. doi: 10.1016/j.ghir.2020.101333. Epub 2020 Jul 18.PMID: 32717585 Free PMC article. Review.

Placental transfusion and short-term outcomes among extremely preterm infants . Kumbhat N, Eggleston B, Davis AS, Van Meurs KP, DeMauro SB, Foglia EE, Lakshminrusimha S, Walsh MC, Watterberg KL, Wyckoff MH, Das A, Handley SC; Generic Database Subcommittee of the NICHD Neonatal Research Network; undefined. Arch Dis Child Fetal Neonatal Ed. 2020 Jul 30:fetalneonatal-2019-318710. doi: 10.1136/archdischild-2019-318710. Online ahead of print. PMID: 32732380

SARS-CoV-2 seroprevalence among parturient women in Philadelphia. Flannery DD, Gouma S, Dhudasia MB, Mukhopadhyay S, Pfeifer MR, Woodford EC, Gerber JS, Arevalo CP, Bolton MJ, Weirick ME, Goodwin EC, Anderson EM, Greenplate AR, Kim J, Han N, Pattekar A, Dougherty J, Kuthuru O, Mathew D, Baxter AE, Vella LA, Weaver J, Verma A, Leite R, Morris JS, Rader DJ, Elovitz MA, Wherry EJ, Puopolo KM, Hensley SE.Sci Immunol. 2020 Jul 29;5(49):eabd5709. doi: 10.1126/sciimmunol.abd5709.PMID: 32727884 Free PMC article.

SARS-CoV-2 Seroprevalence Among Parturient Women. Flannery DD, Gouma S, Dhudasia MB, Mukhopadhyay S, Pfeifer MR, Woodford EC, Gerber JS, Arevalo CP, Bolton MJ, Weirick ME, Goodwin EC, Anderson EM, Greenplate AR, Kim J, Han N, Pattekar A, Dougherty J, Kuthuru O, Mathew D, Baxter AE, Vella LA, Weaver J, Verma A, Leite R, Morris JS, Rader DJ, Elovitz MA, Wherry EJ, Puopolo KM, Hensley SE. medRxiv. 2020 Jul 10:2020.07.08.20149179. doi: 10.1101/2020.07.08.20149179. Preprint. PMID: 32676623 Free PMC article. Updated.

Eric Eichenwald Variation in Car Seat Tolerance Screen Performance in Newborn Nurseries . Davis NL, Hoffman BD, Eichenwald EC. Pediatrics. 2020 Jul 8. pii: e20193593. doi: 10.1542/peds.2019-3593. [Epub ahead of print] PMID: 32641358 [PubMed - as supplied by publisher]

Heidi Herrick, Elizabeth Foglia Provider visual attention on a respiratory function monitor during neonatal resuscitation . Herrick H, Weinberg D, Cecarelli C, Fishman CE, Newman H, den Boer MC, Martherus T, Katz TA, Nadkarni V, Te Pas AB, Foglia EE. Arch Dis Child Fetal Neonatal Ed. 2020 Jul 2. pii: fetalneonatal-2020-319291. doi: 10.1136/archdischild-2020-319291. [Epub ahead of print] PMID: 32616559 [PubMed - as supplied by publisher]

Early-Onset Neonatal Sepsis 2015 to 2017, the Rise of Escherichia coli, and the Need for Novel Prevention Strategies. Stoll BJ, Puopolo KM, Hansen NI, Sánchez PJ, Bell EF, Carlo WA, Cotten CM, D'Angio CT, Kazzi SNJ, Poindexter BB, Van Meurs KP, Hale EC, Collins MV, Das A, Baker CJ, Wyckoff MH, Yoder BA, Watterberg KL, Walsh MC, Devaskar U, Laptook AR, Sokol GM, Schrag SJ, Higgins RD; Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. JAMA Pediatr. 2020 Jul 1;174(7):e200593. doi: 10.1001/jamapediatrics.2020.0593. Epub 2020 Jul 6.PMID: 32364598

Neutrophil extracellular traps activate IL-8 and IL-1 expression in human bronchial epithelia. Hudock KM, Collins MS, Imbrogno M, Snowball J, Kramer EL, Brewington JJ, Gollomp K, McCarthy C, Ostmann AJ, Kopras EJ, Davidson CR, Srdiharan A, Arumugam P, Sengupta S, Xu Y, Worthen GS, Trapnell BC, Clancy JP.Am J Physiol Lung Cell Mol Physiol. 2020 Jul 1;319(1):L137-L147. doi: 10.1152/ajplung.00144.2019. Epub 2020 Mar 11.PMID: 32159969

Nic Bamat, Huayan Zhang, Kristin McKenna, Jason Stoller, Kate Gibbs The Clinical Evaluation of Severe Bronchopulmonary Dysplasia . Bamat NA, Zhang H, McKenna KJ, Morris H, Stoller JZ, Gibbs K. Neoreviews. 2020 Jul;21(7):e442-e453. doi: 10.1542/neo.21-7-e442. Epub 2020 Jul 1. PMID: 32611562 [PubMed - in process]

Drugs to Prevent Bronchopulmonary Dysplasia: Effect of Baseline Risk on the Number Needed to Treat. Jensen EA, Roberts RS, Schmidt B.J Pediatr. 2020 Jul;222:244-247. doi: 10.1016/j.jpeds.2020.01.070. Epub 2020 Mar 3.PMID: 32143932 Review.

Individualising care in severe bronchopulmonary dysplasia: a series of N-of-1 trials comparing transpyloric and gastric feeding. Jensen EA, Zhang H, Feng R, Dysart K, Nilan K, Munson DA, Kirpalani H.Arch Dis Child Fetal Neonatal Ed. 2020 Jul;105(4):399-404. doi: 10.1136/archdischild-2019-317148. Epub 2019 Nov 4.PMID: 31685527 Clinical Trial.

Time to Positivity of Neonatal Blood Cultures for Early-onset Sepsis. Kuzniewicz MW, Mukhopadhyay S, Li S, Walsh EM, Puopolo KM. Pediatr Infect Dis J. 2020 Jul;39(7):634-640. doi: 10.1097/INF.0000000000002632.PMID: 32379197

The Maturation of a Proficient Neonatologist: From the Delivery Room to Independent Practice. French H, Eichenwald E.Pediatrics. 2020 Jul;146(1):e20200212. doi: 10.1542/peds.2020-0212. Epub 2020 Jun 12.PMID: 32532793 No abstract available.

Survival after delivery room cardiopulmonary resuscitation: A national registry study. Foglia EE, Jensen EA, Wyckoff MH, Sawyer T, Topjian A, Ratcliffe SJ; American Heart Association’s Get With The Guidelines-Resuscitation Investigators. Resuscitation. 2020 Jul;152:177-183. doi: 10.1016/j.resuscitation.2020.01.010. Epub 2020 Jan 23.PMID: 31982507

Pharmacologic Management of Severe Bronchopulmonary Dysplasia. Truog WE, Lewis TR, Bamat NA. Neoreviews. 2020 Jul;21(7):e454-e468. doi: 10.1542/neo.21-7-e454.PMID: 32611563

Rebecca Simmons: Maternal and Neonatal Response to COVID-19 . Golden TN, Simmons RA. Am J Physiol Endocrinol Metab. 2020 Jun 23. doi: 10.1152/ajpendo.00287.2020. Online ahead of print. PMID: 32574110

Environmental bioaerosol surveillance as an early warning system for pathogen detection in North Carolina swine farms: A pilot study. Anderson BD, Yondon M, Bailey ES, Duman EK, Simmons RA, Greer AG, Gray GC. Transbound Emerg Dis. 2020 Jun 14. doi: 10.1111/tbed.13683. Online ahead of print. PMID: 32535997

Expanding Access to Continuous EEG Monitoring in Neonatal Intensive Care Units. Fitzgerald MP, Massey SL, Fung FW, Puopolo KM, Posencheg M, Allen-Napoli L, Malcolm M, Abend NS.J Clin Neurophysiol. 2020 Jun 9. doi: 10.1097/WNP.0000000000000730. Online ahead of print. PMID: 32541608

Altered Transcription Factor Binding and Gene Bivalency in Islets of Intrauterine Growth Retarded Rats. Lien YC, Wang PZ, Lu XM, Simmons RA.Cells. 2020 Jun 9;9(6):1435. doi: 10.3390/cells9061435.PMID: 32527043 Free PMC article.

Characterization of Disease Phenotype in Very Preterm Infants with Severe Bronchopulmonary Dysplasia. Wu KY, Jensen EA, White AM, Wang Y, Biko DM, Nilan K, Fraga MV, Mercer-Rosa L, Zhang H, Kirpalani H.Am J Respir Crit Care Med. 2020 Jun 1;201(11):1398-1406. doi: 10.1164/rccm.201907-1342OC.PMID: 31995403

Travers CP, Carlo WA, McDonald SA, Das A, Ambalavanan N, Bell EF, Sánchez PJ, Stoll BJ, Wyckoff MH, Laptook AR, Van Meurs KP, Goldberg RN, D'Angio CT, Shankaran S, DeMauro SB, Walsh MC, Peralta-Carcelen M, Collins MV, Ball MB, Hale EC, Newman NS, Profit J, Gould JB, Lorch SA, Bann CM, Bidegain M, Higgins RD; Racial/Ethnic Disparities Among Extremely Preterm Infants in the United States From 2002 to 2016. Generic Database and Follow-up Subcommittees of the Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. JAMA Netw Open. 2020 Jun 1;3(6):e206757. doi: 10.1001/jamanetworkopen.2020.6757. PMID: 32520359 [PubMed - in process]

Mukhopadhyay S, Puopolo KM, Hansen NI, Lorch SA, DeMauro SB, Greenberg RG, Cotten CM, Sánchez PJ, Bell EF, Eichenwald EC, Stoll BJ; Impact of Early-Onset Sepsis and Antibiotic Use on Death or Survival with Neurodevelopmental Impairment at 2 Years of Age among Extremely Preterm Infants. Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. J Pediatr. 2020 Jun;221:39-46.e5. doi: 10.1016/j.jpeds.2020.02.038. PMID: 32446491 [PubMed - in process]

Mukhopadhyay S, Puopolo KM, Hansen NI, Lorch SA, DeMauro SB, Greenberg RG, Cotten CM, Sánchez PJ, Bell EF, Eichenwald EC, Stoll BJ; Impact of Early-Onset Sepsis and Antibiotic Use on Death or Survival with Neurodevelopmental Impairment at 2 Years of Age among Extremely Preterm Infants. Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. J Pediatr. 2020 Jun;221:39-46.e5. doi: 10.1016/j.jpeds.2020.02.038. PMID: 32446491 [PubMed - in process]

Therapy at 30 days of life predicts lung function at 6 to 12 months in infants with congenital diaphragmatic hernia. Chotzoglou E, Hedrick HL, Herkert LM, Goldshore MA, Rintoul NE, Panitch HB. Pediatr Pulmonol. 2020 Jun;55(6):1456-1467. doi: 10.1002/ppul.24736. Epub 2020 Mar 19.PMID: 32191392

Preventive Health Care Utilization Among Mother-infant Dyads With Medicaid Insurance in the Year Following Birth. Gregory EF, Passarella M, Levine LD, Fiks AG, Lorch SA.Med Care. 2020 Jun;58(6):519-525. doi: 10.1097/MLR.0000000000001310.PMID: 32149923

Agreement between study designs: a systematic review comparing observational studies and randomized trials of surgical treatments for necrotizing enterocolitis. van Heesewijk AE, Rush ML, Schmidt B, Kirpalani H, DeMauro SB. J Matern Fetal Neonatal Med. 2020 Jun;33(12):1965-1973. doi: 10.1080/14767058.2018.1533948. Epub 2018 Dec 17. PMID: 30554539

Pregnancy-associated changes in cervical noncoding RNA. Gerson KD, Haviland MJ, Neo D, Hecht JL, Baccarelli AA, Brennan KJ, Dereix AE, Ralston SJ, Hacker MR, Burris HH. Epigenomics. 2020 Jun;12(12):1013-1025. doi: 10.2217/epi-2019-0231. Epub 2020 Aug 18.PMID: 32808540

Reexamining research on motivations and perspectives of scientists relating to public engagement. Jensen EA. Proc Natl Acad Sci U S A. 2020 May 19;117(20):10628. doi: 10.1073/pnas.2000633117. Epub 2020 Apr 28.PMID: 32345715 Free PMC article. No abstract available.

Antenatal Corticosteroids-Too Much of a Good Thing? DeMauro SB. JAMA. 2020 May 19;323(19):1910-1912. doi: 10.1001/jama.2020.3935.PMID: 32427290 No abstract available.

Kovatis KZ, Di Fiore JM, Martin RJ, Abbasi S, Chaundhary AS, Hoover S, Zhang Z, Kirpalani H. J Pediatr. Effect of Blood Transfusions on Intermittent Hypoxic Episodes in a Prospective Study of Very Low Birth Weight Infants.  2020 May 15. pii: S0022-3476(20)30338-3. doi: 10.1016/j.jpeds.2020.03.015. [Epub ahead of print] PMID: 32423683 [PubMed - as supplied by publisher]

US Hospital Type and Proximity to Mass Shooting Events. Myers SR, DeSimone JD, Lorch SA, Passarella M, Cronin KM, Nance ML.JAMA Surg. 2020 May 1;155(5):446-447. doi: 10.1001/jamasurg.2020.0095.PMID: 32186689 Free PMC article.

Deferred consent for delivery room studies: the providers' perspective. den Boer MC, Houtlosser M, Foglia EE, Lopriore E, de Vries MC, Engberts DP, Te Pas AB.Arch Dis Child Fetal Neonatal Ed. 2020 May;105(3):310-315. doi: 10.1136/archdischild-2019-317280. Epub 2019 Aug 19.PMID: 31427459

Cranial Ultrasound and Minor Motor Abnormalities at 2 Years in Extremely Low Gestational Age Infants. DeMauro SB, Bann C, Flibotte J, Adams-Chapman I, Hintz SR. J Dev Behav Pediatr. 2020 May;41(4):308-315. doi: 10.1097/DBP.0000000000000758.PMID: 31880687

Management of neonatal difficult airway emergencies in the delivery room. Lin EE, Nelson O, Isserman RS, Henderson AA, Rintoul NE, Lioy J, Javia LR, Tran KM, Fiadjoe JE. Paediatr Anaesth. 2020 May;30(5):544-551. doi: 10.1111/pan.13859. Epub 2020 Apr 22.PMID: 32196824

Network Implementation of Guideline for Early Detection Decreases Age at Cerebral Palsy Diagnosis. Maitre NL, Burton VJ, Duncan AF, Iyer S, Ostrander B, Winter S, Ayala L, Burkhardt S, Gerner G, Getachew R, Jiang K, Lesher L, Perez CM, Moore-Clingenpeel M, Lam R, Lewandowski DJ, Byrne R.Pediatrics. 2020 May;145(5):e20192126. doi: 10.1542/peds.2019-2126. Epub 2020 Apr 8.PMID: 32269135

Cervicovaginal microbial communities deficient in Lactobacillus species are associated with second trimester short cervix. Gerson KD, McCarthy C, Elovitz MA, Ravel J, Sammel MD, Burris HH.Am J Obstet Gynecol. 2020 May;222(5):491.e1-491.e8. doi: 10.1016/j.ajog.2019.11.1283. Epub 2019 Dec 6.PMID: 31816307

The CLASSE GATOR (CLinical Acronym SenSE disambiGuATOR): A Method for predicting acronym sense from neonatal clinical notes. Kashyap A, Burris H, Callison-Burch C, Boland MR.Int J Med Inform. 2020 May;137:104101. doi: 10.1016/j.ijmedinf.2020.104101. Epub 2020 Feb 14.PMID: 32088556

Initiating resuscitation before umbilical cord clamping in infants with congenital diaphragmatic hernia: a pilot feasibility trial. Foglia EE, Ades A, Hedrick HL, Rintoul N, Munson DA, Moldenhauer J, Gebb J, Serletti B, Chaudhary A, Weinberg DD, Napolitano N, Fraga MV, Ratcliffe SJ. Arch Dis Child Fetal Neonatal Ed. 2020 May;105(3):322-326. doi: 10.1136/archdischild-2019-317477. Epub 2019 Aug 28.PMID: 31462406 Clinical Trial.

Sedation Practices of Neonates Receiving Extracorporeal Membrane Oxygenation. Franciscovich CD, Monk HM, Brodecki D, Rogers R, Rintoul NE, Hedrick HL, Ely E.ASAIO J. 2020 May;66(5):559-564. doi: 10.1097/MAT.0000000000001043.PMID: 31425254

Providing Care for Infants Born at Home. Watterberg K; COMMITTEE ON FETUS AND NEWBORN.Pediatrics. 2020 May;145(5):e20200626. doi: 10.1542/peds.2020-0626. Epub 2020 Apr 20.PMID: 32312908 Review.

Optimizing Resources in Children's Surgical Care: An Update on the American College of Surgeons' Verification Program. Wang KS, Cummings J, Stark A, Houck C, Oldham K, Grant C, Fallat M; SECTION ON SURGERY, COMMITTEE ON FETUS AND NEWBORN, SECTION ON ANESTHESIOLOGY AND PAIN MEDICINE.Pediatrics. 2020 May;145(5):e20200708. doi: 10.1542/peds.2020-0708. Epub 2020 Apr 20.PMID: 32312909

Impact of flow disruptions in the delivery room. Herrick HM, Lorch S, Hsu JY, Catchpole K, Foglia EE.Resuscitation. 2020 May;150:29-35. doi: 10.1016/j.resuscitation.2020.02.037. Epub 2020 Mar 16.PMID: 32194162

Extracorporeal Life Support Organization (ELSO): Guidelines for Neonatal Respiratory Failure. Wild KT, Rintoul N, Kattan J, Gray B.ASAIO J. 2020 May;66(5):463-470. doi: 10.1097/MAT.0000000000001153.PMID: 32282347 No abstract available.

Maternal stress, low cervicovaginal β-defensin, and spontaneous preterm birth. Burris HH, Riis VM, Schmidt I, Gerson KD, Brown A, Elovitz MA.Am J Obstet Gynecol MFM. 2020 May;2(2):100092. doi: 10.1016/j.ajogmf.2020.100092. Epub 2020 Feb 10.PMID: 32671334

Peer Mentor Development Program: Lessons Learned in Mentoring Racial/Ethnic Minority Faculty. Williams N, Ravenell J, Duncan AF, Butler M, Jean-Louis G, Kalet A. Ethn Dis. 2020 Apr 23;30(2):321-330. doi: 10.18865/ed.30.2.321. eCollection 2020 Spring.PMID: 32346278 Free PMC article.

STEPP IN: Working Together to Keep Infants Warm in the Perioperative Period. Brozanski BS, Piazza AJ, Chuo J, Natarajan G, Grover TR, Smith JR, Mingrone T, McClead RE, Rakesh R, Rintoul N, Guidash J, Bellflower B, Holston M, Richardson T, Pallotto EK. Pediatrics. 2020 Apr;145(4):e20191121. doi: 10.1542/peds.2019-1121. Epub 2020 Mar 19.PMID: 32193210 Review.

Neonatal Partial Liquid Ventilation for the Treatment and Prevention of Bronchopulmonary Dysplasia . Eichenwald C, Dysart K, Zhang H, Fox W. Neoreviews. 2020 Apr;21(4):e238-e248. doi: 10.1542/neo.21-4-e238. PMID: 32238486 Review. No abstract available.

Michael Padula, Huayan Zhang Utility of echocardiography in predicting mortality in infants with severe bronchopulmonary dysplasia . Vyas-Read S, Wymore EM, Zaniletti I, Murthy K, Padula MA, Truog WE, Engle WA, Savani RC, Yallapragada S, Logan JW, Zhang H, Hysinger EB, Grover TR, Natarajan G, Nelin LD, Porta NFM, Potoka KP, DiGeronimo R, Lagatta JM; Children’s Hospitals Neonatal Consortium Severe BPD Focus Group. J Perinatol. 2020 Jan;40(1):149-156. doi: 10.1038/s41372-019-0508-5. Epub 2019 Sep 30. PMID: 31570799 [PubMed - indexed for MEDLINE] Free PMC Article

Gordon SM, Nishiguchi MA, Chase JM, Mani S, Mainigi MA, Behrens EM. IFNs Drive Development of Novel IL-15–Responsive Macrophages. 2020. JImmunol.https://doi.org/10.4049/jimmunol.2000184 .

Johannesson, L, Testa, G, Flyckt, R, Farrell R, Quintini C, Wall A, O’Neill K, Tzakis A, Richards EG, Gordon SM, Porrett PM. Guidelines for standardized nomenclature and reporting in uterus transplantation: An opinion from the United States Uterus Transplant Consortium. Am J Transplant. 2020. https://doi.org/10.1111/ajt.15973 .

Gordon SM, Srinivasan L, Taylor DM, Master SR, Tremoglie, MA, Hankeova A, Flannery DD, Abbasi S, Fitzgerald JC, Harris MC. Derivation of a metabolic signature associated with bacterial meningitis in infants. 2020. Pediatr Res. 88, 184–191. https://doi.org/10.1038/s41390-020-0816-7

Use of prostaglandin E1 to treat pulmonary hypertension in congenital diaphragmatic hernia. Lawrence KM, Berger K, Herkert L, Franciscovich C, O'Dea CLH, Waqar LN, Partridge E, Hanna BD, Peranteau WH, Avitabile CM, Hopper RK, Rintoul NE, Hedrick HL.J Pediatr Surg. 2019 Jan;54(1):55-59. doi: 10.1016/j.jpedsurg.2018.10.039. Epub 2018 Oct 5.PMID: 30442461

Extracorporeal membrane oxygenation and bloodstream infection in congenital diaphragmatic hernia. Keene S, Grover TR, Murthy K, Pallotto EK, Brozanski B, Gien J, Zaniletti I, Johnson YR, Seabrook RB, Porta NFM, Haberman B, DiGeronimo R, Rintoul N; Children’s Hospitals Neonatal Consortium’s (CHNC) Congenital Diaphragmatic Hernia Focus Group. J Perinatol. 2019 Oct;39(10):1384-1391. doi: 10.1038/s41372-019-0435-5. Epub 2019 Aug 5.PMID: 31383944

Pediatric neurosurgeons' views regarding prenatal surgery for myelomeningocele and the management of hydrocephalus: a national survey. Riley JS, Antiel RM, Flake AW, Johnson MP, Rintoul NE, Lantos JD, Traynor MD, Adzick NS, Feudtner C, Heuer GG. Neurosurg Focus. 2019 Oct 1;47(4):E8. doi: 10.3171/2019.7.FOCUS19406.PMID: 31574481

Cardiac Output Measurement Using the Ultrasonic Cardiac Output Monitor: A Validation Study in Newborn Infants. Fraga MV, Dysart KC, Rintoul N, Chaudhary AS, Ratcliffe SJ, Fedec A, Kren S, Cohen MS, Kirpalani H. Neonatology. 2019;116(3):260-268. doi: 10.1159/000501005. Epub 2019 Jul 19.PMID: 31326967

Autism spectrum disorder and neurodevelopmental delays in children with giant omphalocele. Danzer E, Hoffman C, Miller JS, D'Agostino JA, Schindewolf EM, Gerdes M, Bernbaum J, Adams SE, Rintoul NE, Herkert LM, Taylor L, Schreiber J, Peranteau WH, Flake AW, Adzick NS, Hedrick HL.J Pediatr Surg. 2019 Sep;54(9):1771-1777. doi: 10.1016/j.jpedsurg.2019.05.017. Epub 2019 May 28.PMID: 31196668

Lorch SA. Interhospital Transfers for Quality Assessment of Healthcare Systems. J Hosp Med. 2019 Aug;14(8):514-515. doi: 10.12788/jhm.3243. No abstract available.

Boghossian NS, Geraci M, Lorch SA, Phibbs CS, Edwards EM, Horbar JD. Racial and Ethnic Differences Over Time in Outcomes of Infants Born Less Than 30 Weeks' Gestation. Pediatrics. 2019 Aug 12. pii: e20191106. doi: 10.1542/peds.2019-1106. [Epub ahead of print]

Keene S, Grover TR, Murthy K, Pallotto EK, Brozanski B, Gien J, Zaniletti I, Johnson YR, Seabrook RB, Porta NFM, Haberman B, DiGeronimo R, Rintoul N; Children’s Hospitals Neonatal Consortium’s (CHNC) Congenital Diaphragmatic Hernia Focus Group. Extracorporeal membrane oxygenation and bloodstream infection in congenital diaphragmatic hernia. J Perinatol. 2019 Aug 5. doi: 10.1038/s41372-019-0435-5. [Epub ahead of print]

Umoren RA, Sawyer TL, Ades A, DeMeo S, Foglia EE, Glass K, Gray MM, Barry J, Johnston L, Jung P, Kim JH, Krick J, Moussa A, Mulvey C, Nadkarni V, Napolitano N, Quek BH, Singh N, Zenge JP, Shults J, Nishisaki A; National Emergency Airway Registry for Neonates (NEAR4NEOS) Investigators. Team Stress and Adverse Events during Neonatal Tracheal Intubations: A Report from NEAR4NEOS. Am J Perinatol. 2019 Jul 31. doi: 10.1055/s-0039-1693698. [Epub ahead of print]

Natarajan G, Shankaran S, Nolen TL, Sridhar A, Kennedy KA, Hintz SR, Phelps DL, DeMauro SB, Carlo WA, Gantz MG, Das A, Greenberg RG, Younge NE, Bliss JM, Seabrook R, Sánchez PJ, Wyckoff MH, Bell EF, Vohr BR, Higgins RD. Neurodevelopmental Outcomes of Preterm Infants With Retinopathy of Prematurity by Treatment. Pediatrics. 2019 Jul 23. pii: e20183537. doi: 10.1542/peds.2018-3537. [Epub ahead of print]

Fraga MV, Dysart KC, Rintoul N, Chaudhary AS, Ratcliffe SJ, Fedec A, Kren S, Cohen MS, Kirpalani H. Cardiac Output Measurement Using the Ultrasonic Cardiac Output Monitor: A Validation Study in Newborn Infants. Neonatology. 2019 Jul 19:1-9. doi: 10.1159/000501005. [Epub ahead of print]

Root L, van Zanten HA, den Boer MC, Foglia EE, Witlox RSGM, Te Pas AB. Improving Guideline Compliance and Documentation Through Auditing Neonatal Resuscitation. Front Pediatr. 2019 Jul 16;7:294. doi: 10.3389/fped.2019.00294. eCollection 2019.

Edwards L, Cotten CM, Smith PB, Goldberg R, Saha S, Das A, Laptook AR, Stoll BJ, Bell EF, Carlo WA, D'Angio CT, DeMauro SB, Sanchez PJ, Shankaran S, Van Meurs KP, Vohr BR, Walsh MC, Malcolm WF; Eunice Kennedy Shriver National Institute of Child Health and Human Development. Inadequate oral feeding as a barrier to discharge in moderately preterm infants. J Perinatol. 2019 Jul 11. doi: 10.1038/s41372-019-0422-x. [Epub ahead of print]

Puopolo KM, Lynfield R, Cummings JJ; COMMITTEE ON FETUS AND NEWBORN; COMMITTEE ON INFECTIOUS DISEASES. Management of Infants at Risk for Group B Streptococcal Disease. Pediatrics. 2019 Jul 8. pii: e20191881. doi: 10.1542/peds.2019-1881. [Epub ahead of print]

Handley SC, Srinivas SK, Lorch SA. Regionalization of Care and the Maternal-Infant Dyad Disconnect. JAMA. 2019 Jul 8. doi: 10.1001/jama.2019.6403. [Epub ahead of print] No abstract available.

Ansems SM, Kirpalani H, Mercer-Rosa L, Wang Y, Hopper RK, Fraga MV, Jensen EA. Patent Ductus Arteriosus and the Effects of Its Late Closure in Preterm Infants with Severe Bronchopulmonary Dysplasia. Neonatology. 2019 Jul 3:1-8. doi: 10.1159/000500269. [Epub ahead of print]

Bamat NA, Kirpalani H, Feudtner C, Jensen EA, Laughon MM, Zhang H, Monk HM, Passarella M, Lorch SA. Medication use in infants with severe bronchopulmonary dysplasia admitted to United States children's hospitals. J Perinatol. 2019 Jun 21. doi: 10.1038/s41372-019-0415-9. [Epub ahead of print]

Dekker J, van Kaam AH, Roehr CC, Flemmer AW, Foglia EE, Hooper SB, Te Pas AB. Stimulating and maintaining spontaneous breathing during transition of preterm infants. Pediatr Res. 2019 Jun 19. doi: 10.1038/s41390-019-0468-7. [Epub ahead of print] Review.

Russell MW, Moldenhauer JS, Rychik J, Burnham NB, Zullo E, Parry SI, Simmons RA, Elovitz MA, Nicolson SC, Linn RL, Johnson MP, Yu S, Sampson MG, Hakonarson H, Gaynor JW. Damaging Variants in Proangiogenic Genes Impair Growth in Fetuses with Cardiac Defects. J Pediatr. 2019 Jun 18. pii: S0022-3476(19)30578-5. doi: 10.1016/j.jpeds.2019.05.013. [Epub ahead of print]

Machut KZ, Datta A, Stoller JZ, Rao R, Mathur A, Grover TR, Billimoria Z, Murthy K. Association of Neonatologist Continuity of Care and Short-Term Patient Outcomes. J Pediatr. 2019 Jun 11. pii: S0022-3476(19)30589-X. doi: 10.1016/j.jpeds.2019.05.023. [Epub ahead of print]

Ekhaguere O, Patel S, Kirpalani H. Nasal Intermittent Mandatory Ventilation Versus Nasal Continuous Positive Airway Pressure Before and After Invasive Ventilatory Support. Clin Perinatol. 2019 Sep;46(3):517-536. doi: 10.1016/j.clp.2019.05.004. Epub 2019 Jun 20. Review.

den Boer MC, Houtlosser M, Foglia EE, Davis PG, van Kaam AH, Kamlin COF, Schmölzer GM, de Vries MC, Te Pas AB. Deferred consent for the enrolment of neonates in delivery room studies: strengthening the approach. Arch Dis Child Fetal Neonatal Ed. 2019 May 9. pii: fetalneonatal-2018-316461. doi: 10.1136/archdischild-2018-316461. [Epub ahead of print] No abstract available.

Ozawa Y, Ades A. Foglia E. DeMeo S, Barry J, Sawyer T, Singh N, Glass K, Jung P, Quek B, Johnston L, Kim J, Napolitano N, Shults J, Nadkarni V, Nishisaki A for the Near4NEOS Investigators. Premedication with neuromuscular blockade and sedation during neonatal intubation is associated with fewer adverse events. J Perinatol. 2019 Apr 2. doi: 10.1038/s41372-019-0367-0. [Epub ahead of print]

Burris HH, Lorch SA, Kirpalani H, Pursley DM, Elovitz MA, Clougherty JE. Racial disparities in preterm birth in the US; a biosensor of physical and social environmental exposures. Arch Dis Child. 2019 Mar 8. pii: archdischild-2018-316486. doi: 10.1136/archdischild-2018-316486. [Epub ahead of print]

DeMauro SB, Jensen E, Bann C, Bell E, Hibbs AM, Hintz S, Lorch S: Home Oxygen and 2-Year Outcomes of Preterm Infants with Bronchopulmonary Dysplasia. Pediatrics e-pub ahead of print, April 2019.

Brumbaugh JE, Sridhar A, Bell EF, Hansen HI, Carlo WA, Hintz SR, Vohr BR, Colaizy TT, Duncan AF, Wyckoff MH, Baack ML, Rysavy MA DeMauro SB, Stoll BJ, Das A, Higgins RD: The Tiniest Babies: Outcomes of Extremely Preterm Infants with Birth Weight Less than 400 Grams. JAMA Pediatrics e-pub ahead of print, March 2019.

Pellegrin S, Munoz FM, Padula MA, Heath PT, Meller L, Top K, Wilmshurst J, Wiznitzer M, Manoja Das MK, Hahn CD, Kucuku M, Oleske J, Vinayan KP, Yozawitz E, Aneja S, Bhat N, Boylan G, Sesay S, Shrestha A, Soul JS, Tagbo B, Joshi J, Soe A, Maltezou HC, Gidudu J, Kochhar S, and Pressler RM for the Brighton Collaboration Neonatal Seizures Working Group: Neonatal Seizures: Case Definition & Guidelines for Data Collection, Analysis, and Presentation of Immunization Safety Data. Vaccine 2019.

Villagomez AN, Munoz AM, Peterson RL, Colbert AM, Gladstone M, MacDonald B, Wilson R, Fairlie L, Gerner GJ, Patterson J, Boghossian NS, Burton VJ, Cortés M, Katikaneni LD, Gildey Larson JC, Angulo AS, Joshi J, Nesin M, Padula MA, Kochhar S, and Connery AK for The Brighton Collaboration Neurodevelopmental Delay Working Group. Neurodevelopmental Delay: Case Definition & Guidelines for Data Collection, Analysis, and Presentation of Immunization Safety Data. Vaccine 2019.

Kirpalani H, Ratcliffe SJ, Keszler M, Davis PG, Foglia EE, Te Pas A, Fernando M, Chaudhary A, Localio R, van Kaam AH, Onland W, Owen LS, Schmölzer GM, Katheria A, Hummler H, Lista G, Abbasi S, Klotz D, Simma B, Nadkarni V, Poulain FR, Donn SM, Kim HS, Park WS, Cadet C, Kong JY, Smith A, Guillen U, Liley HG, Hopper AO, Tamura M; SAIL Site Investigators. Effect of Sustained Inflations vs Intermittent Positive Pressure Ventilation on Bronchopulmonary Dysplasia or Death Among Extremely Preterm Infants: The SAIL Randomized Clinical Trial. JAMA. 2019 Mar 26;321(12):1165-1175. doi: 10.1001/jama.2019.1660. PMID: 30912836

Sawyer T, Foglia EE. Resuscitation Quality Metrics for the Newly Born. Am J Perinatol. 2019 Mar 1. doi: 10.1055/s-0039-1681098. [Epub ahead of print] PMID: 30822798

Horbar JD, Edwards EM, Greenberg LT, Profit J, Draper D, Helkey D, Lorch SA, Lee HC, Phibbs CS, Rogowski J, Gould JB, Firebaugh G. Racial Segregation and Inequality in the Neonatal Intensive Care Unit for Very Low-Birth-Weight and Very Preterm Infants. JAMA Pediatr. 2019 Mar 25. doi: 10.1001/jamapediatrics.2019.0241. [Epub ahead of print]

Brady J, Kovatis K, O Apos Dea CL, Gray M, Ades A. What Do NICU Fellows Identify as Important for Achieving Competency in Neonatal Intubation? Neonatology. 2019 Mar 19;116(1):10-16. [Epub ahead of print] PMID: 30889585 

Masten M, Sommerfeldt S, Gordan S, Greubel E, Canning C, Lioy J, Chuo J. Evaluating Teamwork in the Neonatal Intensive Care Unit: A Survey of Providers and Parents. Adv Neonatal Care. 2019 Mar 19. doi: 10.1097/ANC.0000000000000604. [Epub ahead of print]

DeMauro SB, Bellamy SL, Fernando M, Hoffmann J, Gratton T, Schmidt B; PROP Investigators. Patient, Family, and Center-Based Factors Associated with Attrition in Neonatal Clinical Research: A Prospective Study. Neonatology. 2019 Mar 5;115(4):328-334. doi: 10.1159/000494105. [Epub ahead of print]

Masino AJ, Harris MC, Forsyth D, Ostapenko S, Srinivasan L, Bonafide CP, Balamuth F, Schmatz M, Grundmeier RW. Machine learning models for early sepsis recognition in the neonatal intensive care unit using readily available electronic health record data. PLoS One. 2019 Feb 22;14(2):e0212665. doi: 10.1371/journal.pone.0212665. eCollection 2019.

Sawyer T, Foglia EE, Ades A, Moussa A, Napolitano N, Glass K, Johnston L, Jung P, Singh N, Quek BH, Barry J, Zenge J, DeMeo SD, Brei B, Krick J, Kim JH, Nadkarni V, Nishisaki A; National Emergency Airway Registry for Neonates (NEAR4NEOS) investigators. Incidence, impact and indicators of difficult intubations in the neonatal intensive care unit: a report from the National Emergency Airway Registry for Neonates. Arch Dis Child Fetal Neonatal Ed. 2019 Feb 22. pii: fetalneonatal-2018-316336. doi: 10.1136/archdischild-2018-316336. [Epub ahead of print] PMID: 3079605

Bozzuto L, Passarella M, Lorch S, Srinivas S. Effects of Delivery Volume and High-Risk Condition Volume on Maternal Morbidity Among High-Risk Obstetric Patients. Obstet Gynecol. 2019 Feb;133(2):261-268

Chuo J, Lioy J, Gerdes J. Drivers of referrals to a children’s hospital neonatal–infant intensive care unit. J Perinatol. 2019 Feb;39(2):295-299. doi: 10.1038/s41372-018-0297-2. Epub 2018 Dec 20.

Handley S, Passarella M, Lorch S, Lee H: Survey of Preterm Neuro-Centric Care Practices in California Neonatal Intensive Care Units. J Perinatol 39(2): 256-262, Feb 2019.

Sawyer T, Foglia E, Ades A, Moussa A, Napolitano N, Glass K, Johnston L, Jung P, Singh N, Quek B, Nadkarni V, Nishisaki A for the NEAR4NEOS investigators. Incidence and Indicators of Difficult Intubations in the NICU. Arch Dis Child Fetal Neonatal Ed. Feb. 2019.

Bamat N, Fierro J, Wang Y, Millar D, Kirpalani H. Positive end-expiratory pressure for preterm infants requiring conventional mechanical ventilation for respiratory distress syndrome or bronchopulmonary dysplasia. Cochrane Database Syst Rev. 2019 Feb 26;2:CD004500. doi: 10.1002/14651858.CD004500.pub3.

Lee K, Lorch SA, Small DS. Sensitivity analyses for average treatment effects when outcome is censored by death in instrumental variable models. Stat Med. 2019 Feb 20. doi: 10.1002/sim.8117. [Epub ahead of print]

Ekhaguere OA, Padula MA, Jensen EA. Use of Point-of-Care Gastric pH Testing to Assess the Efficacy of Acid Suppression Therapy in the Neonatal Intensive Care Unit. Am J Perinatol. 2019 Feb 19. doi: 10.1055/s-0039-1679917. [Epub ahead of print]

Enlow E, Gray MM, Wallace-Keeshen S, D'Agostino JA, Abbasi S, Lorch SA. Health literacy of parents of very preterm infants at NICU admission and discharge: a prospective cohort study. J Perinatol. 2019 Feb 15. doi: 10.1038/s41372-019-0340-y. [Epub ahead of print]

Burris HH, Hwang SS, Collins JW Jr, Kirpalani H, Wright CJ. Re-conceptualizing Associations between Race and Morbidities of Extreme Prematurity. J Pediatr. 2019 Feb 2. pii: S0022-3476(18)31826-2. doi: 10.1016/j.jpeds.2018.12.052. [Epub ahead of print]

Lawrence KM, Berger K, Herkert L, Franciscovich C, O'Dea CLH, Waqar LN, Partridge E, Hanna BD, Peranteau WH, Avitabile CM, Hopper RK, Rintoul NE, Hedrick HL. Use of prostaglandin E1 to treat pulmonary hypertension in congenital diaphragmatic hernia. J Pediatr Surg. 2019 Jan;54(1):55-59. doi: 10.1016/j.jpedsurg.2018.10.039. Epub 2018 Oct 5.

Shankaran S, Bell EF, Laptook AR, Saha S, Newman NS, Kazzi SNJ, Barks J, Stoll BJ, Bara R, Gabrio J, Childs K, Das A, Higgins RD, Carlo WA, Sánchez PJ, Carlton DP, Pavageau L, Malcolm WF, D'Angio CT, Ohls RK, Poindexter BB, Sokol GM, Van Meurs KP, Colaizy TT, Khmour A, Puopolo KM, Garg M, Walsh MC; Eunice Kennedy Shriver National Institute of Child Health, and Human Development Neonatal Research Network. Weaning of Moderately Preterm Infants from the Incubator to the Crib: A Randomized Clinical Trial. J Pediatr. 2019 Jan;204:96-102.e4. doi: 10.1016/j.jpeds.2018.08.079. PMID: 30337189

Foglia EE, Ades A, Sawyer T, Glass KM, Singh N, Jung P, Quek BH, Johnston LC, Barry J, Zenge J, Moussa A, Kim JH, DeMeo SD, Napolitano N, Nadkarni V, Nishisaki A; NEAR4NEOS Investigators. Neonatal Intubation Practice and Outcomes: An International Registry Study. Pediatrics. 2019 Jan;143(1). pii: e20180902. doi: 10.1542/peds.2018-0902. Epub 2018 Dec 11. PMID: 30538147

Sillers L, Handley SC, James JR, Foglia EE. Pulseless Electrical Activity Complicating Neonatal Resuscitation. Neonatology. 2019;115(2):95-98.. doi: 10.1159/000493357. Epub 2018 Oct 23. PMID: 30352434

DeMauro SB, Bellamy SL, Fernando M, Hoffmann J, Gratton T, Schmidt B: Patient, Family, and Center-Based Factors Associated with Attrition in Neonatal Clinical Research: A Prospective Study. Neonatology 115(4): 328-334, January 2019.

Phibbs CS, Schmitt SK, Cooper M, Gould JB, Lee HC, Profit J, Lorch SA: Birth Hospitalization Costs and Days of Care for Mothers and Neonates in California, 2009-2011. J Pediatr. 2019 Jan;204:118-125.e14. doi: 10.1016/j.jpeds.2018.08.041. Epub 2018 Oct 5.

Predicting Risk of Infection in Infants with Congenital Diaphragmatic Hernia. Murthy K, Porta NFM, Pallotto EK, Rintoul N, Keene S, Chicoine L, Gien J, Brozanski BS, Johnson YR, Haberman B, DiGeronimo R, Zaniletti I, Grover TR; Children's Hospitals Neonatal Consortium (CHNC) Congenital Diaphragmatic Hernia Focus Group. J Pediatr. 2018 Dec;203:101-107.e2. doi: 10.1016/j.jpeds.2018.07.032. Epub 2018 Sep 11.PMID: 30217691

Reduced oxygen concentration for the resuscitation of infants with congenital diaphragmatic hernia. Riley JS, Antiel RM, Rintoul NE, Ades AM, Waqar LN, Lin N, Herkert LM, D'Agostino JA, Hoffman C, Peranteau WH, Flake AW, Adzick NS, Hedrick HL.J Perinatol. 2018 Jul;38(7):834-843. doi: 10.1038/s41372-017-0031-5. Epub 2018 Jun 11.PMID: 29887609

Treprostinil Improves Persistent Pulmonary Hypertension Associated with Congenital Diaphragmatic Hernia. Lawrence KM, Hedrick HL, Monk HM, Herkert L, Waqar LN, Hanna BD, Peranteau WH, Rintoul NE, Hopper RK. J Pediatr. 2018 Sep;200:44-49. doi: 10.1016/j.jpeds.2018.04.052. Epub 2018 May 18.PMID: 29784517

Short-Term Neurodevelopmental Outcome in Children Born With High-Risk Congenital Lung Lesions. Danzer E, Hoffman C, D'Agostino JA, Boelig MM, Gerdes M, Bernbaum JC, Rosenthal H, Waqar LN, Rintoul NE, Herkert LM, Kallan MJ, Peranteau WH, Flake AW, Adzick NS, Hedrick HL.Ann Thorac Surg. 2018 Jun;105(6):1827-1834. doi: 10.1016/j.athoracsur.2018.01.033. Epub 2018 Feb 10.PMID: 29438655

Rate and Risk Factors Associated with Autism Spectrum Disorder in Congenital Diaphragmatic Hernia. Danzer E, Hoffman C, D'Agostino JA, Miller JS, Waqar LN, Gerdes M, Bernbaum JC, Rosenthal H, Rintoul NE, Herkert LM, Peranteau WH, Flake AW, Adzick NS, Hedrick HL.J Autism Dev Disord. 2018 Jun;48(6):2112-2121. doi: 10.1007/s10803-018-3472-6.PMID: 29383650

Extracorporeal membrane oxygenation in infants with congenital diaphragmatic hernia. Grover TR, Rintoul NE, Hedrick HL. Semin Perinatol. 2018 Mar;42(2):96-103. doi: 10.1053/j.semperi.2017.12.005. Epub 2018 Jan 12.PMID: 29338874 Review.

Anticoagulation in neonatal ECMO. Kamdar A, Rintoul N, Raffini L. Semin Perinatol. 2018 Mar;42(2):122-128. doi: 10.1053/j.semperi.2017.12.008. Epub 2018 Jan 12.PMID: 29336832 Review.

Short-Term Neurodevelopmental Outcome in Congenital Diaphragmatic Hernia: The Impact of Extracorporeal Membrane Oxygenation and Timing of Repair. Danzer E, Hoffman C, D'Agostino JA, Connelly JT, Waqar LN, Gerdes M, Bernbaum J, Rintoul NE, Herkert LM, Peranteau WH, Flake AW, Adzick NS, Hedrick HL. Pediatr Crit Care Med. 2018 Jan;19(1):64-74. doi: 10.1097/PCC.0000000000001406.PMID: 29303891

Introduction: Update on neonatal extracorporeal membrane oxygenation. Johnston LC, Rintoul NE, Ades AM. Semin Perinatol. 2018 Mar;42(2):65-67. doi: 10.1053/j.semperi.2017.12.001. Epub 2017 Dec 29.PMID: 29291939 No abstract available.

Acquired Infection and Antimicrobial Utilization During Initial NICU Hospitalization in Infants With Congenital Diaphragmatic Hernia. Keene S, Murthy K, Pallotto E, Brozanski B, Gien J, Zaniletti I, Hulbert C, Seabrook R, Rintoul N, Chicoine L, Porta N, Grover TR. Pediatr Infect Dis J. 2018 May;37(5):469-474. doi: 10.1097/INF.0000000000001835.PMID: 29189614

van Heesewijk AE, Rush ML, Schmidt B, Kirpalani H, DeMauro SB: Agreement between study designs: A systematic review comparing observational studies and randomized trials of surgical treatments for necrotizing enterocolitis. Journal of Maternal-Fetal & Neonatal Medicine Page: 1-9, December 2018.

Guttmann K, Flibotte J, DeMauro SB: Parental Perspectives on Diagnosis and Prognosis of NICU Graduates with Cerebral Palsy. Journal of Pediatrics 203: 156-162, December 2018.

Costeloe K, Turner MA, Padula MA, Shah PS, Modi N, Soll R, Haumont D, Kusuda S, Göpel W, Chang YS, Smith PB, Lui K, Davis JM, Hudson LD: International Neonatal Consortium. Sharing Data to Accelerate Medicine Development and Improve Neonatal Care: Data Standards and Harmonized Definitions. Journal of Pediatrics Dec 2018.

den Boer MC, Houtlosser M, Foglia EE, Tan RNGB, Engberts DP, Te Pas AB. Benefits of recording and reviewing neonatal resuscitation: the providers' perspective. Arch Dis Child Fetal Neonatal Ed. 2018 Dec 1. pii: fetalneonatal-2018-315648. doi: 10.1136/archdischild-2018-315648. [Epub ahead of print] PMID: 30504441

Puopolo KM, Benitz WE, Zaoutis TE; Committee on Fetus and Newborn; Committee on Infectious Diseases. Management of Neonates Born at ≤34 6/7 Weeks' Gestation With Suspected or Proven Early-Onset Bacterial Sepsis. Pediatrics. 2018 Dec;142(6). pii: e20182896. doi: 10.1542/peds.2018-2896. PMID: 30455344

Puopolo KM, Benitz WE, Zaoutis TE; Committee on Fetus and Newborn; Committee on Infectious Diseases. Management of Neonates Born at ≥35 0/7 Weeks' Gestation With Suspected or Proven Early-Onset Bacterial Sepsis. Pediatrics. 2018 Dec;142(6). pii: e20182894. doi: 10.1542/peds.2018-2894. PMID: 30455342

Sanders AP, Svensson K, Gennings C, Burris HH, Oken E, Amarasiriwardena C, Basnet P, Pizano-Zarate ML, Schnaas L, Tamayo-Ortiz M, Baccarelli AA, Satlin LM, Wright RO, Tellez-Rojo MM. Prenatal lead exposure modifies the effect of shorter gestation on increased blood pressure in children. Environ Int. 2018 Nov;120:464-471. doi: 10.1016/j.envint.2018.08.038.

Kennedy EB, Hacker MR, Miedema D, Pursley DM, Modest AM, Golen TH, Burris HH. NICU admissions after a policy to eliminate elective early term deliveries before 39 weeks of gestation. Hospital Pediatrics, 2018 Nov;8(11):686-692.

Fishman CE, Weinberg DD, Murray A, Foglia EE. Accuracy of real-time delivery room resuscitation documentation. Arch Dis Child Fetal Neonatal Ed. 2018 Nov 24. pii: fetalneonatal-2018-315723. doi: 10.1136/archdischild-2018-315723. [Epub ahead of print] PMID: 30472661

MR Boland, A Kashyap, J Xiong, JH Holmes, S Lorch: Development and Validation of the PEPPER Framework (Prenatal Exposure PubMed ParsER) with Applications to Food Additives. J Am Med Inform Assoc. 2018 Nov 1;25(11):1432-1443. doi: 10.1093/jamia/ocy119.

GBD 2017 Mortality Collaborators. Global, regional, and national age-sex-specific mortality and life expectancy, 1950-2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet 2018 Nov 10;392(10159):1684-1735. doi: 10.1016/S0140-6736(18)31891-9. Epub 2018 Nov 8.

Brady JM, Zhang H, Kirpalani H, DeMauro SB: Living with severe bronchopulmonary dysplasia - Parental views of their child's quality of life Journal of Pediatrics November 2018 Notes: e-pub ahead of print.

Chawla S, Natarajan G, Chawdhury D, Das A, Walsh M, Bell EF, Laptook AR, Van Meurs K, D'Angio CT, Stoll BJ, DeMauro SB Shankaran S: Neonatal Morbidities among Moderately Preterm Infants Exposed to Antenatal Corticosteroids. American Journal of Perinatology 35(12): 1213-1221, October 2018.

Phelps DL, Watterberg KL, Nolen TL, Cole CC, Cotten CM, Oh W, Poindexter BB, Zaterka-Baxter KM, Das A, Backstrom Lacy C, Scorsone AM, Walsh MC, Bell EF, Kennedy KA, Schibler K, Sokol GM, Laughon MM, Lakshminrusimha S, Truog WE, Garg M, Carlo WA, Laptook AR, Van Meurs KP, Carlton DP, Graf A, DeMauro SB, Brion LP, Shankaran S, Orge FH, Olson RJ, Mintz-Hittner H, Yang MB, Haider KM, Wallace DK, Chung M, Hug D, Tsui I, Cogen MS, Donahue JP, Gaynon M, Hutchinson AK, Bremer DL, Quinn G, He YG, Lucas Jr WR, Winter TW, Kicklighter SD, Kumar K, Chess PR, Colaizy TT, Hibbs AM, Ambalavanan N, Harmon HH, McGowan EC, Higgins RD, for the Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network: Effects of Myo-inositol on Type 1 Retinopathy of Prematurity Among Preterm Infants <28 Weeks' Gestational Age: A Randomized Clinical Trial. Journal of the American Medical Association 320(16): 1649-1658, October 2018.

French H, Gray M, Gillam-Krakauer M, Bonachea E, Carbajal M, Payne A, Vasquez M, Rubinos L, Falck A, Izatt S, Dadiz R. Flipping the Classroom: A National Pilot Curriculum for Physiology in Neonatal-Perinatal Medicine. Journal of Perinatology 2018 Oct;38(10):1420-1427

Murthy K, Porta NFM, Pallotto EK, Rintoul N, Keene S, Children's Hospitals Neonatal Consortium (CHNC) Congenital Diaphragmatic Hernia Focus Group, et al. J Pediatr. 2018 Dec;203:101-107.e2. doi: 10.1016/j.jpeds.2018.07.032. Epub 2018 Sep 11.

Laue HE, Cassoulet R, Abdelouahab N, Serme-Gbedo YK, Desautels AS, Brennan KJM, Bellenger JP, Burris HH, Coull BA, Weisskopf MG, Takser L, Baccarelli AA. Association Between Meconium Acetaminophen and Childhood Neurocognitive Development in GESTE, a Canadian Cohort Study. Toxicol Sci. 2018 Sep 7. doi: 10.1093/toxsci/kfy222. PMID: 30202886.

Lagatta JM, Hysinger EB, Zaniletti I, Padula MA, Zhang H, Grover TR, Engle WA, Murthy K; Children's Hospital Neonatal Consortium Severe BPD Focus Group, et al. The Impact of Pulmonary Hypertension in Preterm Infants with Severe Bronchopulmonary Dysplasia through 1 Year. J Pediatr. 2018 Dec;203:218-224.e3. doi: 10.1016/j.jpeds.2018.07.035. Epub 2018 Aug 29.

Johnston L, Sawyer T, Nishisaki A, Whitfill T, French H, Glass K, Dadiz R, Bruno C, Levit O, Gangadharan S, Scherzer D, Moussa A, Auerbach M;INSPIRE Research Network. Neonatal Intubation Competency Assessment Tool: Development and Validation. Acad Pediatr. August 2018.

Mukhopadhyay S, Sengupta S, Puopolo KM. Challenges and opportunities for antibiotic stewardship among preterm infants. Arch Dis Child Fetal Neonatal Ed. 2018 Nov 13. pii: fetalneonatal-2018-315412. doi: 10.1136/archdischild-2018-315412. [Epub ahead of print] Review. PMID: 30425110

Flannery DD, Ross RK, Mukhopadhyay S, Tribble AC, Puopolo KM, Gerber JS. Temporal Trends and Center Variation in Early Antibiotic Use Among Premature Infants. JAMA Network Open. 2018;1(1):e180164.

Flannery DD, Puopolo KM. Neonatal Antibiotic Use: How Much is Too Much? Pediatrics. 2018; 142(3):e20181942

Flannery DD, Puopolo KM. Neonatal Antibiotic Use: What Are We Doing and Where Shall We Go? Neoreviews, American Academy of Pediatrics. 2018;19(9):e516-525

Lawrence KM, Hedrick HL, Monk HM, Herkert L, Waqar LN, Hanna BD, Peranteau WH, Rintoul NE, Hopper RK. Treprostinil Improves Persistent Pulmonary Hypertension Associated with Congenital Diaphragmatic Hernia. J Pediatr. 2018 Sep;200:44-49. doi: 10.1016/j.jpeds.2018.04.052. Epub 2018 May 18.

Bonafide CP, Localio AR, Ferro DF, Orenstein EW, Jamison DT, Lavanchy C, Foglia EE. Accuracy of Pulse Oximetry-Based Home Baby Monitors. JAMA. 2018 Aug 21;320(7):717-719. doi: 10.1001/jama.2018.9018. No abstract available. PMID: 30140866

Schumacher DJ, King B, Barnes MM, Elliott S, Gibbs K, McGreey JF, Gonzalez del Rey J, Sharma T, Michelson C, Schwartz A, and the APPD LEARN CCC Study Group: The Influence of the Review Process Utilized by Clinical Competency Committee Members on their Summative Assessment Decisions of Residents. Journal of Graduate Medical Education 2018, August 2018, Vol. 10, No. 4, pp. 429-437.

LINE- and Alu-containing genomic instability hotspot at 16q24.1 associated with recurrent and nonrecurrent CNV deletions causative for ACDMPV. Szafranski P, Kosmider E, Liu Q, Karolak JA, Currie L, Parkash S, Kahler SG, Roeder E, Littlejohn RO, DeNapoli TS, Shardonofsky FR, Henderson C, Powers G, Poisson V, Berube D, Oligny L, Michaud JL, Janssens S, De Coen K, Van Dorpe J, Dheedene A, Harting MT, Weaver MD, Khan AM, Tatevian N, Wambach J, Gibbs K, Popek E, Gambin A, Stankiewicz P. Human Mutation August 2018.

Friedman S, Moerdler S, Malbari A, Latiman B, Gibbs K. The Pediatric Resident Teaching Group: The Development and Evaluation of a Longitudinal Resident as Teacher Program.  Medical Science Educator July 2018. 

Kirpalani H, Stark MJ, Andersen C. On the Gendering of Plasma: What is Transfusion-Related Acute Lung Injury to Bronchopulmonary Dysplasia? J Pediatr. 2018 Jul 13. pii: S0022-3476(18)30771-6. doi: 10.1016/j.jpeds.2018.06.002. [Epub ahead of print]

Hwang SS, Burris HH, Collins JW Jr, Kirpalani H, Wright CJ. Moving beyond race and ethnicity to understand the effect of inhaled nitric oxide on bronchopulmonary dysplasia prevention. J Pediatr. 2018 Jul 17. pii: S0022-3476(18)30834-5. [Epub ahead of print]

Luo J, Shepard S, Nilan K, Wood A,  Monk HM, Jensen EA, Harrington AT,  Maschhoff K, Kirpalani H, Feng Z,  Zhang H. Improved growth and developmental activity post tracheostomy in preterm infants with severe BPD. Pediatr Pulmonol. 2018 Jul 3. doi: 10.1002/ppul.24087. [Epub ahead of print]

Pouppirt NR, Nassar R, Napolitano N, Nawab U, Nishisaki A, Nadkarni V, Ades A, Foglia EE. Association Between Video Laryngoscopy and Adverse Tracheal Intubation-Associated Events in the Neonatal Intensive Care Unit. J Pediatr. 2018 Jul 3. pii: S0022-3476(18)30759-5. doi: 10.1016/j.jpeds.2018.05.046. [Epub ahead of print]

Eichenwald EC; Committee on Fetus and Newborn. Diagnosis and Management of Gastroesophageal Reflux in Preterm Infants. Pediatrics. 2018 Jul;142(1). pii: e20181061. doi: 10.1542/peds.2018-1061. Epub 2018 Jun 18.

Flannery DD, Dysart K, Cook A, Greenspan J, Aghai ZH, Jensen EA. Association Between Early Antibiotic Exposure and Bronchopulmonary Dysplasia or Death. J Perinatol, Epub ahead of print, June 13, 2018.

Xin F, Fischer E, Krapp C, Krizman EN, Lan Y, Mesaros C, Snyder NW, Bansal A, Robinson MB, Simmons RA, Bartolomei MS. Mice exposed to bisphenol A exhibit depressive-like behavior with neurotransmitter and neuroactive steroid dysfunction. Horm Behav. 2018 May 12. pii: S0018-506X(18)30023-0. doi: 10.1016/j.yhbeh.2018.05.010. [Epub ahead of print]

Handley SC, Passarella M, Lee HC, Lorch SA. Incidence Trends and Risk Factor Variation in Severe Intraventricular Hemorrhage across a Population Based Cohort. J Pediatr. 2018 May 10. pii: S0022-3476(18)30510-9. doi: 10.1016/j.jpeds.2018.04.020. [Epub ahead of print]

Baumgarten HD, Gebb JS, Khalek N, Moldenhauer JS, Johnson MP, Peranteau WH, Hedrick HL, Adzick NS, Flake AW. Preemptive Delivery and Immediate Resection for Fetuses with High-Risk Sacrococcygeal Teratomas. Fetal Diagn Ther. 2018 May 7;:1-8. [Epub ahead of print] PMID: 29734172 

Jensen EA, Foglia EE, Dysart KC, Simmons RA, Aghai ZH, Cook A, Greenspan JS, DeMauro SB. Adverse effects of small for gestational age differ by gestational week among very preterm infants. Arch Dis Child Fetal Neonatal Ed. 2018 May 5. pii: fetalneonatal-2017-314171. doi: 10.1136/archdischild-2017-314171. [Epub ahead of print]

Pouppirt NR, Foglia EE, Ades A. A video is worth a thousand words: innovative uses of videolaryngoscopy. Arch Dis Child Fetal Neonatal Ed. 2018 May 4;. [Epub ahead of print] PMID: 29728413

Foglia EE, Te Pas AB. Effective ventilation: The most critical intervention for successful delivery room resuscitation. Semin Fetal Neonatal Med. 2018 Apr 17. pii: S1744-165X(18)30065-9. doi: 10.1016/j.siny.2018.04.001. [Epub ahead of print] Review.

Unolt M, Versacci P, Anaclerio S, Lambiase C, Calcagni G, Trezzi M, Carotti A, Crowley TB, Zackai EH, Goldmuntz E, Gaynor JW, Digilio MC, McDonald-McGinn DM, Marino B. Congenital heart diseases and cardiovascular abnormalities in 22q11.2 deletion syndrome: From well-established knowledge to new frontiers. Am J Med Genet A. 2018 Apr 16;. [Epub ahead of print] PMID: 29663641

Wai KC, Hibbs AM, Steurer MA, Black DM, Asselin JM, Eichenwald EC, Ballard PL, Ballard RA, Keller RL; Trial of Late Surfactant (TOLSURF) Study Group. Maternal Black Race and Persistent Wheezing Illness in Former Extremely Low Gestational Age Newborns: Secondary Analysis of a Randomized Trial. J Pediatr. 2018 Apr 4. pii: S0022-3476(18)30220-8. doi: 10.1016/j.jpeds.2018.02.032. [Epub ahead of print]

DeMauro SB, Schmidt B. Comparing Like with Like When Reporting Neurodevelopmental Outcomes after Preterm Birth. J Pediatr. 2018 Mar 15. pii: S0022-3476(18)30066-0. doi: 10.1016/j.jpeds.2018.01.042. [Epub ahead of print] No abstract available. PMID: 29551315 [PubMed - as supplied by publisher]

Drago MJ, Guillén U, Schiaratura M, Batza J, Zygmunt A, Mowes A, Munson D, Lorenz JM, Farkouh-Karoleski C, Kirpalani H. Constructing a Culturally Informed Spanish Decision-Aid to Counsel Latino Parents Facing Imminent Extreme Premature Delivery. Matern Child Health J. 2018 Mar 8. doi: 10.1007/s10995-018-2471-8. [Epub ahead of print] PMID: 29520727 [PubMed - as supplied by publisher]

Adzick NS, De Leon DD, States LJ, Lord KL, Bhatti TR, Becker SA, Stanley CA.: Surgical Treatment of Congenital Hyperinsulinism: Results from 495 Pancreatectomies in Neonates and Children. American Pediatric Surgical Association March 2018 Notes: presentation March 12.

Alexander J, Teague AM, Chen J, Aston CE, Leung YK, Chernausek S, Simmons RA, Pinney SE. Offspring sex impacts DNA methylation and gene expression in placenta from women with diabetes during pregnancy. PLoS One. 2018 Feb 22;13(2):e0190698. doi: 10.1371/journal.pone.0190698. eCollection 2018.

Farmer DL, Thom EA, Brock JW, Burrows PK, Johnson MP, Howell LJ, Farrell JA, Gupta N5, Adzick NS. Management of Myelomeningocele Study Investigators. The Management of Myelomeningocele Study: full cohort 30-month pediatric outcomes. Am J Obstet Gynecol. 2018 Feb;218(2): Epub 2017 Dec 12. PMID: 29246577

Gaynor JW, Parry S, Moldenhauer JS, Simmons RA, Rychik J, Ittenbach RF, Russell WW, Zullo E, Ward JL, Nicolson SC, Spray TL, Johnson MP. The impact of the maternal-fetal environment on outcomes of surgery for congenital heart disease in neonates. Eur J Cardiothorac Surg. 2018 Feb 13. doi: 10.1093/ejcts/ezy015. [Epub ahead of print]

Chuo J, Lioy J, Gerdes J. Drivers of referrals to a children's hospital neonatal-infant intensive care unit. J Perinatol. 2019 Feb;39(2):295-299. doi: 10.1038/s41372-018-0297-2. Epub 2018 Dec 20.

den Boer MC, Houtlosser M, van Zanten HA, Foglia EE, Engberts DP, Te Pas AB. Ethical dilemmas of recording and reviewing neonatal resuscitation. Arch Dis Child Fetal Neonatal Ed. 2018 Jan 20. pii: fetalneonatal-2017-314191. doi: 10.1136/archdischild-2017-314191. [Epub ahead of print] Review. PMID: 29353257

Huberts TJP, Foglia EE, Narayen IC, van Vonderen JJ, Hooper SB, Te Pas AB. The Breathing Effort of Very Preterm Infants at Birth. J Pediatr. 2018 Jan 12. pii: S0022-3476(17)31501-9. doi: 10.1016/j.jpeds.2017.11.008. [Epub ahead of print]. PMID: 29336795

Stuart TJ, O'Neill K, Condon D, Sasson I, Sen P, Xia Y, Simmons RA. Diet-induced obesity alters the maternal metabolome and early placenta transcriptome and decreases placenta vascularity in the mouse. Biol Reprod. 2018 Jan 18. doi: 10.1093/biolre/ioy010. [Epub ahead of print] PMID: 29360948

Rashid CS, Lien YC, Bansal A, Jaeckle-Santos LJ, Li C, Won KJ, Simmons RA. Transcriptomic analysis reveals novel mechanisms mediating islet dysfunction in the intrauterine growth restricted (IUGR) rat. Endocrinology. 2018 Jan 4. doi: 10.1210/en.2017-00888. [Epub ahead of print] PMID: 29309562

Bamat N, Bryan M, Jensen EA. Inconsistent conclusions of statistical significance based on p-values and confidence intervals. J Perinatol. 2018 Jan 3. doi: 10.1038/s41372-017-0027-1. [Epub ahead of print] No abstract available. PMID: 29298983

Phibbs CS, Lorch SA. Choice of Hospital as a Source of Racial/Ethnic Disparities in Neonatal Mortality and Morbidity Rates. JAMA Pediatr. 2018 Jan 2. doi: 10.1001/jamapediatrics.2017.4917. [Epub ahead of print] No abstract available. PMID: 29297051

Mukhopadhyay S, Puopolo KM. Preventing Neonatal Group B Streptococcus Disease: The Limits of Success. JAMA Pediatr. 2019 Jan 14. doi: 10.1001/jamapediatrics.2018.4824. [Epub ahead of print] PMID: 30640370

Greenberg RG, Chowdhury D, Hansen NI, Smith PB, Stoll BJ, Sánchez PJ, Das A, Puopolo KM, Mukhopadhyay S, Higgins RD, Cotten CM; Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. Prolonged duration of early antibiotic therapy in extremely premature infants. Pediatr Res. 2019 Jan 22. doi: 10.1038/s41390-019-0300-4. [Epub ahead of print]. PMID: 30737489

Weighing the Social and Ethical Considerations of Maternal-Fetal Surgery. Antiel RM, Flake AW, Collura CA, Johnson MP, Rintoul NE, Lantos JD, Curlin FA, Tilburt JC, Brown SD, Feudtner C.Pediatrics. 2017 Dec;140(6):e20170608. doi: 10.1542/peds.2017-0608. Epub 2017 Nov 3.PMID: 29101225 Free article.

Growth trajectory and neurodevelopmental outcome in infants with congenital diaphragmatic hernia. Antiel RM, Lin N, Licht DJ, Hoffman C, Waqar L, Xiao R, Monos S, D'Agostino JA, Bernbaum J, Herkert LM, Rintoul NE, Peranteau WH, Flake AW, Adzick NS, Hedrick HL.J Pediatr Surg. 2017 Dec;52(12):1944-1948. doi: 10.1016/j.jpedsurg.2017.08.063. Epub 2017 Sep 28.PMID: 29079316

Attitudes of paediatric and obstetric specialists towards prenatal surgery for lethal and non-lethal conditions. Antiel RM, Curlin FA, Lantos JD, Collura CA, Flake AW, Johnson MP, Rintoul NE, Brown SD, Feudtner C.J Med Ethics. 2018 Apr;44(4):234-238. doi: 10.1136/medethics-2017-104377. Epub 2017 Oct 10.PMID: 29018178

Physician views regarding the benefits and burdens of prenatal surgery for myelomeningocele. Antiel RM, Collura CA, Flake AW, Johnson MP, Rintoul NE, Lantos JD, Curlin FA, Tilburt JC, Brown SD, Feudtner C.J Perinatol. 2017 Sep;37(9):994-998. doi: 10.1038/jp.2017.75. Epub 2017 Jun 15.PMID: 28617430

Specialty-Based Variation in Applying Maternal-Fetal Surgery Trial Evidence. Antiel RM, Flake AW, Johnson MP, Khalek N, Rintoul NE, Lantos JD, Curlin FA, Tilburt JC, Feudtner C.Fetal Diagn Ther. 2017;42(3):210-217. doi: 10.1159/000455024. Epub 2017 Mar 17.PMID: 28301843

Short-term weight gain velocity in infants with congenital diaphragmatic hernia (CDH). Gien J, Murthy K, Pallotto EK, Brozanski B, Chicoine L, Zaniletti I, Seabrook R, Keene S, Alapati D, Porta N, Rintoul N, Grover TR; Children's Hospitals Neonatal Consortium CDH Study Group.Early Hum Dev. 2017 Mar-Apr;106-107:7-12. doi: 10.1016/j.earlhumdev.2017.01.010. Epub 2017 Feb 6.PMID: 28178582

Electrographic Seizures in Children and Neonates Undergoing Extracorporeal Membrane Oxygenation. Lin JJ, Banwell BL, Berg RA, Dlugos DJ, Ichord RN, Kilbaugh TJ, Kirsch RE, Kirschen MP, Licht DJ, Massey SL, Naim MY, Rintoul NE, Topjian AA, Abend NS. Pediatr Crit Care Med. 2017 Mar;18(3):249-257. doi: 10.1097/PCC.0000000000001067.PMID: 28099234 Free PMC article.

Management and outcomes of scoliosis in children with congenital diaphragmatic hernia. Antiel RM, Riley JS, Cahill PJ, Campbell RM, Waqar L, Herkert LM, Rintoul NE, Peranteau WH, Flake AW, Adzick NS, Hedrick HL.J Pediatr Surg. 2016 Dec;51(12):1921-1925. doi: 10.1016/j.jpedsurg.2016.09.013. Epub 2016 Sep 15.PMID: 28029369

Venoarterial Extracorporeal Life Support for Neonatal Respiratory Failure: Indications and Impact on Mortality. Bamat NA, Tharakan SJ, Connelly JT, Hedrick HL, Lorch SA, Rintoul NE, Williams SB, Dysart KC.ASAIO J. 2017 Jul/Aug;63(4):490-495. doi: 10.1097/MAT.0000000000000495.PMID: 27984316 Free PMC article.

Bamat NA, Guevara JP, Bryan M, Roberts RS, Yoder BA, Lemyre B, Chiu A, Millar D, Kirpalani H. Variation in Positive End-Expiratory Pressure Levels for Mechanically Ventilated Extremely Low Birth Weight Infants. J Pediatr. 2017 Dec 22. pii: S0022-3476(17)31485-3. doi: 10.1016/j.jpeds.2017.10.065. [Epub ahead of print]

Jensen EA, Foglia EE, Dysart KC, Aghai ZH, Cook A, Greenspan JS, DeMauro SB. Car Seat Tolerance Screening in the Neonatal Intensive Care Unit: Failure Rates, Risk Factors, and Adverse Outcomes. J Pediatr. 2017 Dec 18. pii: S0022-3476(17)31503-2. doi: 10.1016/j.jpeds.2017.11.010. [Epub ahead of print]

Keene S, Murthy K, Pallotto E, Brozanski B, Gien J, Zaniletti I, Hulbert C, Seabrook R, Rintoul N, Chicoine L, Porta N, Grover TR. Acquired Infection and Antimicrobial Utilization During Initial NICU Hospitalization in Infants with Congenital Diaphragmatic Hernia. Pediatr Infect Dis J. 2017 Nov 16. doi: 10.1097/INF.0000000000001835. [Epub ahead of print]

James J, Munson D, DeMauro SB, Langer JC, Dworetz AR, Natarajan G, Bidegain M, Fortney CA, Seabrook R, Vohr BR, Tyson JE, Bell EF, Poindexter BB, Shankaran S, Higgins RD, Das A, Stoll BJ, Kirpalani H; Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. Outcomes of Preterm Infants following Discussions about Withdrawal or Withholding of Life Support. J Pediatr. 2017 Nov;190:118-123.e4. doi: 10.1016/j.jpeds.2017.05.056. [Epub ahead of print]

Hwang MF, Beechinor RJ, Wade KC, Benjamin DK Jr, Smith PB, Hornik CP, Capparelli EV, Duara S, Kennedy KA, Cohen-Wolkowiez M, Gonzalez D. External Evaluation of Two Fluconazole Infant Population Pharmacokinetic Models. Antimicrob Agents Chemother. 2017 Sep 11. pii: AAC.01352-17. doi: 10.1128/AAC.01352-17. [Epub ahead of print]

Goyal MK, Johnson TJ, Chamberlain JM, Casper TC, Simmons T, Alessandrini EA, Bajaj L, Grundmeier RW, Gerber JS, Lorch SA, Alpern ER. Pediatric Care Applied Research Network (PECARN). Racial and Ethnic Differences in Antibiotic Use for Viral Illness in Emergency Departments. Pediatrics. 2017 Sep 5. pii: e20170203. doi: 10.1542/peds.2017-0203. [Epub ahead of print]

Lorch SA. Health Equity and Quality of Care Assessment: A Continuing Challenge. Pediatrics. 2017 Sep;140(3). pii: e20172213. doi: 10.1542/peds.2017-2213.

Lorch SA. Perinatal legislative policies and health outcomes. Semin Perinatol. 2017 Aug 28. pii: S0146-0005(17)30078-2. doi: 10.1053/j.semperi.2017.07.006. [Epub ahead of print]

Lorch SA. Understanding pregnancy outcomes using epidemiology and health services research. Semin Perinatol. 2017 Aug 28. pii: S0146-0005(17)30080-0. doi: 10.1053/j.semperi.2017.07.008. [Epub ahead of print]

Jensen EA, Lorch SA. Association between off-peak hour birth and neonatal morbidity and mortality among very low birth weight infants. J Pediatr. 2017 Jul;186:41-48.e4. doi: 10.1016/j.jpeds.2017.02.007. Epub 2017 Mar 8.

Foglia EE, Jensen EA, Kirpalani H. State of the Art Review: Delivery room interventions to prevent bronchopulmonary dysplasia in extremely preterm infants. J Perinatol. 2017. June 1 [Epub ahead of print].

Scott Lorch. Continuity of Care in Infancy and Early Childhood Health Outcomes. Enlow E, Passarella M, Lorch SA. Pediatrics. 2017 Jun 15. pii: e20170339. doi: 10.1542/peds.2017-0339. [Epub ahead of print] PMID: 28617244

Jennifer James, David Munson, Sara DeMauro, Haresh Kirpalani. Outcomes of Preterm Infants following Discussions about Withdrawal or Withholding of Life Support. James J, Munson D, DeMauro SB, Langer JC, Dworetz AR, Natarajan G, Bidegain M, Fortney CA, Seabrook R, Vohr BR, Tyson JE, Bell EF, Poindexter BB, Shankaran S, Higgins RD, Das A, Stoll BJ, Kirpalani H; Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. J Pediatr. 2017 Jun 21. pii: S0022-3476(17)30749-7. doi: 10.1016/j.jpeds.2017.05.056. [Epub ahead of print] PMID: 28647272 [PubMed - as supplied by publisher]

Hysinger EB, Friedman NL, Padula MA, Shinohara RT, Zhang H, Panitch HB, Kawut SM. Tracheobronchomalacia is associated with increased morbidity in bronchopulmonary dysplasia. Ann Am Thorac Soc. 2017 Jun 16. doi: 10.1513/AnnalsATS.201702-178OC. [Epub ahead of print]

Schmidt B, Roberts RS, Anderson PJ, Asztalos EV, Costantini L, Davis PG, Dewey D, D'Ilario J, Doyle LW, Grunau RE, Moddemann D, Nelson H, Ohlsson A, Solimano A, Tin W, Caffeine for Apnea of Prematurity (CAP) Trial Group. Academic Performance, Motor Function, and Behavior 11 Years After Neonatal Caffeine Citrate Therapy for Apnea of Prematurity: An 11-Year Follow-up of the CAP Randomized Clinical Trial. JAMA Pediatr. 2017 Apr 24. doi: 10.1001/jamapediatrics.2017.0238. [Epub ahead of print] PMID: 28437520

Emily A. Partridge, Marcus G. Davey, Matthew A. Hornick, Patrick E. McGovern, Ali Y. Mejaddam, Jesse D. Vrecenak, Carmen Mesas-Burgos, Aliza Olive, Robert C. Caskey, Theodore R. Weiland III, Jiancheng Han, James T. Connelly, Kevin C. Dysart, Alexander J. Schupper, Jack Rychik, Holly L. Hedrick, William H. Peranteau, and Alan W. Flake. “An extra-uterine physiologic support system for the extreme premature lamb.” Nature Communications. Published online April 25, 2017.

Partridge EA, Davey MG, Hornick MA, McGovern PE, Mejaddam AY, Vrecenak JD, Mesas-Burgos C, Olive A, Caskey RC, Weiland TR, Han J, Schupper AJ, Connelly JT, Dysart KC, Rychik J, Hedrick HL, Peranteau WH, Flake AW. An extra-uterine system to physiologically support the extreme premature lamb. Nat Commun. 2017 Apr 25;8:15112.

Partridge EA, Davey MG, Hornick MA, McGovern PE,  Mejaddam AY, Vrecenak JD, Mesas-Burgos C, Olive A, Caskey RC, Weiland TR, Han J, Schupper AJ, Connelly JT, Dysart KC, Rychik J, Hedrick HL, Peranteau WH, Flake AW. Corrigendum: An extra-uterine system to physiologically support the extreme premature lamb. Nat Commun. 2017 May 23;8:15794. Doi: 10.1038/ncomms15794.

Tkach EK, White AM, Dysart KC, Waber B, Nawab US, Zhang H, Jensen EA. Comparison of Intact Parathyroid Hormone, Alkaline Phosphatase, Phosphate Levels for Diagnosing Severe Metabolic Bone Disease in Infants with Severe Bronchopulmonary Dysplasia. Am J Perinatol. 2017 Apr 21. doi: 10.1055/s-0037-1602419. [Epub ahead of print]

Walsh MC, Bell EF, Kandefer S, Saha S, Carlo WA, D'Angio CT, Laptook AR, Sanchez PJ, Stoll BJ, Shankaran S, Van Meurs KP, Cook N, Higgins RD, Das A, Newman NS, Schibler K, Schmidt B, Cotten CM, Poindexter BB, Watterberg KL, Truog WE. Neonatal outcomes of moderately preterm infants compared to extremely preterm infants. Pediatr Res. 2017 Apr 18. [Epub ahead of print] 

Niles DE, Cines C, Insley E, Foglia EE, Elci OU, Skåre C, Olasveengen T, Ades A, Posencheg M, Nadkarni VM, Kramer-Johansen J. Incidence and characteristics of positive pressure ventilation delivered to newborns in a US tertiary academic hospital. Resuscitation. 2017 Apr 11. pii: S0300-9572(17)30135-1. [Epub ahead of print] 

Sawyer T, Foglia EE, Hatch LD, Moussa A, Ades A, Johnston L, Nishisaki A. Improving neonatal intubation safety: A journey of a thousand miles. J Neonatal Perinatal Med. 2017 Apr 8. [Epub ahead of print]

Kuzniewicz MW, Puopolo KM, Fischer A, Walsh EM, Li S, Newman TB, Kipnis P, Escobar GJ. A Quantitative, Risk-Based Approach to the Management of Neonatal Early-Onset Sepsis. JAMA Pediatr. 2017 Apr 1;171(4):365-371.

Barbara Schmidt, Lis Foglia. The Effect of Skin Pigmentation on the Accuracy of Pulse Oximetry in Infants with Hypoxemia. Foglia EE, Whyte RK, Chaudhary A, Mott A, Chen J, Propert KJ, Schmidt B. J Pediatr. 2017 Mar;182:375-377.e2. doi: 10.1016/j.jpeds.2016.11.043. Epub 2016 Dec 9. PMID: 27939107 [PubMed - indexed for MEDLINE]

Barbara Schmidt. Benefits of Oxygen Saturation Targeting Trials: Oximeter Calibration Software Revision and Infant Saturations. Whyte RK, Nelson H, Roberts RS, Schmidt B. J Pediatr. 2017 Mar;182:382-384. doi: 10.1016/j.jpeds.2016.11.076. Epub 2017 Jan 12. Review. PMID: 28088392 [PubMed - indexed for MEDLINE]

Flannery DD, Foglia EE. The contributions of red blood cell transfusion and severe anemia in necrotizing enterocolitis: causes or confounders? J Perinatol. 2017 Mar 23. [Epub ahead of print]

Schmidt B, Whyte RK, Roberts RS. Oxygen Targeting in Infants Born Extremely Preterm Who Are Small for Gestational Age: A Need for Heightened Vigilance. J Pediatr. 2017 Mar 15. pii: S0022-3476(17)30337-2. [Epub ahead of print] 

Srinivasan L, Page G, Kirpalani H, Murray JC, Das A, Higgins RD, Carlo WA, Bell EF, Goldberg RN, Schibler K, Sood BG, Stevenson DK, Stoll BJ, Van Meurs KP, Johnson KJ, Levy J, McDonald SA, Zaterka-Baxter KM, Kennedy KA, Sánchez PJ, Duara S, Walsh MC, Shankaran S, Wynn JL, Cotten CM; Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. Genome-wide association study of sepsis in extremely premature infants. Arch Dis Child Fetal Neonatal Ed. 2017 Mar 10. pii: fetalneonatal-2016-311545. [Epub ahead of print]

Gien J, Murthy K, Pallotto EK, Brozanski B, Chicoine L, Zaniletti I, Seabrook R, Keene S, Alapati D, Porta N, Rintoul N, Grover TR. Children's Hospitals Neonatal Consortium CDH Study Group. Short-term weight gain velocity in infants with congenital diaphragmatic hernia (CDH). Early Hum Dev. 2017 Feb 5;106-107:7-12. [Epub ahead of print]

Lemyre B, Davis PG, De Paoli AG, Kirpalani H. Nasal intermittent positive pressure ventilation (NIPPV) versus nasal continuous positive airway pressure (NCPAP) for preterm neonates after extubation. Cochrane Database Syst Rev. 2017 Feb 1;2:CD003212. 

Jensen EA, Dysart KC, Gantz MG, Carper B, Higgins RD, Keszler M, Laughon MM, Poindexter BB, Stoll BJ, Walsh MC, Schmidt B, For the Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. Association between use of prophylactic indomethacin and the risk for bronchopulmonary dysplasia in extremely preterm infants. J Pediatr. 2017 Jul;186:34-40.e2. doi: 10.1016/j.jpeds.2017.02.003. Epub 2017 Feb 28.

Abman SH, Collaco JM, Shepherd EG, Keszler M, Cuevas-Guaman M, Welty SE5, Truog WE, McGrath-Morrow SA, Moore PE, Rhein LM, Kirpalani H, Zhang H, Gratny LL, Lynch SK, Curtiss J, Stonestreet BS, McKinney RL, Dysart KC, Gien J, Baker CD, Donohue PK, Austin E, Fike C, Nelin LD; Bronchopulmonary Dysplasia Collaborative. Interdisciplinary Care of Children with Severe Bronchopulmonary Dysplasia. J Pediatr. 2017 Feb;181:12-28.e1. doi: 10.1016/j.jpeds.2016.10.082. Epub 2016 Nov 28.

Giaccone A, Zuppa AF, Sood B, Cohen MS, O'Byrne ML, Moorthy G, Mathur A, Kirpalani H. Milrinone Pharmacokinetics and Pharmacodynamics in Neonates with Persistent Pulmonary Hypertension of the Newborn. Am J Perinatol. 2017 Jan 18. [Epub ahead of print] 

Foglia EE, Langeveld R, Heimall L, Deveney A, Ades A, Jensen EA, Nadkarni VM. Incidence, characteristics, and survival following cardiopulmonary resuscitation in the quaternary neonatal intensive care unit. Resuscitation. 2017 Jan;110:32-36. doi: 10.1016/j.resuscitation.2016.10.012. Epub 2016 Oct 27.

Tramper J, Zhang H, Foglia EE, Dysart KC, Padula MA, Sullivan KV, Jensen EA. The association between positive tracheal aspirate cultures and adverse pulmonary outcomes in preterm infants with severe bronchopulmonary dysplasia. Am J Perinatol. 2017 Jan;34(1):96-104. doi: 10.1055/s-0036-1584541. Epub 2016 Jun 10.

Gordon SM, Srinivasan L and Harris MC. Neonatal Meningitis: Overcoming Challenges in Diagnosis, Prognosis, and Treatment with Omics. 2017. Front. Pediatr. 5:139. https://doi.org/10.3389/fped.2017.00139

Neurodevelopmental outcomes at 5years of age in congenital diaphragmatic hernia. Danzer E, Hoffman C, D'Agostino JA, Gerdes M, Bernbaum J, Antiel RM, Rintoul NE, Herkert LM, Flake AW, Adzick NS, Hedrick HL.J Pediatr Surg. 2017 Mar;52(3):437-443. doi: 10.1016/j.jpedsurg.2016.08.008. Epub 2016 Aug 30.PMID: 27622588

Right- versus left-sided congenital diaphragmatic hernia: a comparative outcomes analysis. Partridge EA, Peranteau WH, Herkert L, Rendon N, Smith H, Rintoul NE, Flake AW, Adzick NS, Hedrick HL. J Pediatr Surg. 2016 Jun;51(6):900-2. doi: 10.1016/j.jpedsurg.2016.02.049. Epub 2016 Mar 3.PMID: 27342009

Rate of increase of lung-to-head ratio over the course of gestation is predictive of survival in left-sided congenital diaphragmatic hernia. Partridge EA, Peranteau WH, Herkert L, Rintoul NE, Flake AW, Adzick NS, Hedrick HL.J Pediatr Surg. 2016 May;51(5):703-5. doi: 10.1016/j.jpedsurg.2016.02.006. Epub 2016 Feb 11.PMID: 27261559

Predicting death or extended length of stay in infants with congenital diaphragmatic hernia. Murthy K, Pallotto EK, Gien J, Brozanski BS, Porta NF, Zaniletti I, Keene S, Chicoine LG, Rintoul NE, Dykes FD, Asselin JM, Short BL, Padula MA, Durand DJ, Reber KM, Evans JR, Grover TR. J Perinatol. 2016 Aug;36(8):654-9. doi: 10.1038/jp.2016.26. Epub 2016 Mar 10.PMID: 26963428

Younger gestational age is associated with increased risk of adverse neurodevelopmental outcome during infancy in congenital diaphragmatic hernia. Danzer E, Gerdes M, D'Agostino JA, Bernbaum J, Hoffman C, Herkert LM, Rintoul NE, Peranteau WH, Flake AW, Adzick NS, Hedrick HL.J Pediatr Surg. 2016 Jul;51(7):1084-90. doi: 10.1016/j.jpedsurg.2015.12.010. Epub 2016 Jan 5.PMID: 2683153

Bamat NA, Tharakan SJ, Connelly JT, Hedrick HL, Lorch SA, Rintoul NE, Williams SB, Dysart KC. Venoarterial extracorporeal life support for neonatal respiratory failure: indications and impact on mortality. ASAIO J. 2016 Dec 13. [Epub ahead of print]

Jensen EA, Panitch H, Feng R, Moore PE, Schmidt B. Inter-observer reliability of the respiratory physical examination in premature infants: A multi-center study. J Pediatr. 2016 Nov;178:87-92. doi: 10.1016/j.jpeds.2016.07.039. Epub 2016 Aug 24.

Guillén Ú, Suh S, Wang E, Stickelman V, Kirpalani H. Development of a video decision aid to inform parents on potential outcomes of extreme prematurity. J Perinatol . 2016 Nov;36(11):939-943. doi: 10.1038/jp.2016.127.

Martin AE, D'Agostino JA, Passarella M, Lorch SA. Racial differences in parental satisfaction with neonatal intensive care unit nursing care. J Perinatol . 2016 Nov;36(11):1001-1007. doi: 10.1038/jp.2016.142.

Srinivasan L, Kilpatrick L, Shah SS, Abbasi S, Harris MC. Cerebrospinal fluid cytokines in the diagnosis of bacterial meningitis in infants. Pediatr Res . 2016 Oct;80(4):566-72. doi: 10.1038/pr.2016.117. Epub 2016 May 26.

Zhang H, Zhang J, Zhao S. Airway damage of prematurity: The impact of prolonged intubation, ventilation, and chronic lung disease. Semin Fetal Neonatal Med . 2016 Aug;21(4):246-53. doi: 10.1016/j.siny.2016.04.001. Epub 2016 Apr 26. PMID: 26948885.

Foglia EE, Owen LS, Keszler M, Davis PG, Kirpalani H. Obtaining informed consent for delivery room research: the investigators' perspective. Arch Dis Child Fetal Neonatal Ed . 2016 Aug 11. pii: fetalneonatal-2016-310934. doi: 10.1136/archdischild-2016-310934. [Epub ahead of print]. PMID: 27515986.

Kirpalani H, Truog WE, D'Angio CT, Cotten M. Recent controversies on comparative effectiveness research investigations: Challenges, opportunities, and pitfalls. Semin Perinatol . 2016 Jul 13. pii: S0146-0005(16)30004-0. doi: 10.1053/j.semperi.2016.05.004. [Epub ahead of print]. PMID: 27423511.

Mukhopadhyay S, Meyer SA, Permar SR, Puopolo KM. Symptomatic Postnatal Cytomegalovirus Testing among Very Low-Birth-Weight Infants: Indications and Outcomes. A m J Perinatol . 2016 Jul;33(9):894-902. doi: 10.1055/s-0036-1581080. Epub 2016 Apr 8. PMID: 27057771

Bamat N, Jensen EA, Kirpalani H. Duration of continuous positive airway pressure in premature infants. Semin Fetal Neonatal Med . 2016 Jun;21(3):189-95. doi: 10.1016/j.siny.2016.02.005. Epub 2016 Mar 3. PMID: 26948885.

Peltz A, Wu CL, White ML, Wilson KM, Lorch SA, Thurm C, Hall M, Berry JG. Characteristics of Rural Children Admitted to Pediatric Hospitals. Pediatrics . 2016 May;137(5). pii: e20153156. doi: 10.1542/peds.2015-3156. Epub 2016 Apr 11. PMID: 27244794.

Zubizarreta JR, Lorch SA, Marshall G, D'Apremont I, Tapia JL. Effect of prophylactic CPAP in very low birth weight infants in South America.  J Perinatol . 2016 Apr 7. doi: 10.1038/jp.2016.56. [Epub ahead of print] PMID: 27054844.

Sengupta S, Yang G, O'Donnell JC, Hinson MD, McCormack SE, Falk MJ, La P, Robinson MB, Williams ML, Yohannes MT, Polyak E, Nakamaru-Ogiso E, Dennery PA. The circadian gene Rev-erbα improves cellular bioenergetics and provides preconditioning for protection against oxidative stress. Free Radic Biol Med . 2016 Apr;93:177-89. doi: 10.1016/j.freeradbiomed.2016.02.004. Epub 2016 Feb 5. PMID: 26855417

Wright CJ, Polin RA, Kirpalani H. Continuous Positive Airway Pressure to Prevent Neonatal Lung Injury: How Did We Get Here, and How Do We Improve?  J Pediatr . 2016 Mar 26. pii: S0022-3476(16)00281-X. doi: 10.1016/j.jpeds.2016.02.059. [Epub ahead of print] No abstract available. PMID: 27025910.

Massaro AN, Murthy K, Zaniletti I, Cook N, DiGeronimo R, Dizon ML, Hamrick SE, McKay VJ, Natarajan G, Rao R, Richardson T, Smith D, Mathur AM; Children's Hospital Neonatal Consortium. Intercenter cost variation for perinatal hypoxic-ischemic encephalopathy in the era of therapeutic hypothermia.  J Pediatr . Epub ahead of print 2016 Mar 16. pii: S0022-3476(16)00197-9. doi: 10.1016/j.jpeds.2016.02.033. PMID: 26995699.

Jensen EA1, Chaudhary A2, Bhutta ZA3, Kirpalani H4. Non-invasive respiratory support for infants in low- and middle-income countries. Semin Fetal Neonatal Med . 2016 Feb 22. doi: 10.1016/j.siny.2016.02.003.

Kozhimannil KB, Hung P, Casey MM, Lorch SA. Factors associated with high-risk rural women giving birth in non-NICU hospital settings. J Perinatol . 2016 Feb 18. doi: 10.1038/jp.2016.8.

Mukhopadhyay S, Maurer R, Puopolo KM. Neonatal Transcutaneous Carbon Dioxide Monitoring--Effect on Clinical Management and Outcomes. Respir Care . 2016 Jan;61(1):90-7. doi: 10.4187/respcare.04212. Epub 2015 Oct 27. PMID: 26508771

Jensen EA, White AM, Liu P, Yee K, Waber B, Monk HM, Zhang H. Determinants of Severe Metabolic Bone Disease in Very Low-Birth-Weight Infants with Severe Bronchopulmonary Dysplasia Admitted to a Tertiary Referral Center. Am J Perinato l. 2016 Jan;33(1):107-13. doi: 10.1055/s-0035-1560043. Epub 2015 Aug 21. PMID: 26295968

Hemolysis-Associated Nitric Oxide Dysregulation during Extracorporeal Membrane Oxygenation. Sulkowski JP, Cooper JN, Pearson EG, Connelly JT, Rintoul N, Kilbaugh TJ, Deans KJ, Minneci PC. J Extra Corpor Technol. 2014 Sep;46(3):217-23.PMID: 26357787 Free PMC article.

Short-term outcomes and medical and surgical interventions in infants with congenital diaphragmatic hernia. Grover TR, Murthy K, Brozanski B, Gien J, Rintoul N, Keene S, Najaf T, Chicoine L, Porta N, Zaniletti I, Pallotto EK; Children's Hospitals Neonatal Consortium. Am J Perinatol. 2015 Sep;32(11):1038-44. doi: 10.1055/s-0035-1548729. Epub 2015 Mar 31.PMID: 25825963

Neurodevelopmental outcome at one year of age in congenital diaphragmatic hernia infants not treated with extracorporeal membrane oxygenation. Danzer E, Gerdes M, D'Agostino JA, Bernbaum J, Hoffman C, Herkert L, Rintoul NE, Peranteau WH, Flake AW, Adzick NS, Hedrick HL.J Pediatr Surg. 2015 Jun;50(6):898-903. doi: 10.1016/j.jpedsurg.2015.03.040. Epub 2015 Mar 19.PMID: 2581820

Systemic hypertension in giant omphalocele: An underappreciated association. Peranteau WH, Tharakan SJ, Partridge E, Herkert L, Rintoul NE, Flake AW, Adzick NS, Hedrick HL.J Pediatr Surg. 2015 Sep;50(9):1477-80. doi: 10.1016/j.jpedsurg.2015.02.051. Epub 2015 Feb 23.PMID: 25783355

Patient characteristics are important determinants of neurodevelopmental outcome during infancy in giant omphalocele. Danzer E, Gerdes M, D'Agostino JA, Bernbaum J, Hoffman C, Rintoul NE, Herkert LM, Flake AW, Adzick NS, Hedrick HL.Early Hum Dev. 2015 Mar;91(3):187-93. doi: 10.1016/j.earlhumdev.2014.12.009. Epub 2015 Feb 9.PMID: 25676186

Brain-type natriuretic peptide levels correlate with pulmonary hypertension and requirement for extracorporeal membrane oxygenation in congenital diaphragmatic hernia. Partridge EA, Hanna BD, Rintoul NE, Herkert L, Flake AW, Adzick NS, Hedrick HL, Peranteau WH.J Pediatr Surg. 2015 Feb;50(2):263-6. doi: 10.1016/j.jpedsurg.2014.11.009. Epub 2014 Nov 7.PMID: 25638615

Timing of repair of congenital diaphragmatic hernia in patients supported by extracorporeal membrane oxygenation (ECMO). Partridge EA, Peranteau WH, Rintoul NE, Herkert LM, Flake AW, Adzick NS, Hedrick HL.J Pediatr Surg. 2015 Feb;50(2):260-2. doi: 10.1016/j.jpedsurg.2014.11.013. Epub 2014 Nov 7.PMID: 25638614

Foglia EE, DeMauro SB, Dysart K, Kirpalani H. When has enough evidence accumulated to change neonatal practice? Semin Fetal Neonatal Med. 2015 Dec;20(6):424-30. doi: 10.1016/j.siny.2015.09.003. Epub 2015 Oct 4.

Hall SL, Cross J, Selix NW, Patterson C, Segre L, Chuffo-Siewert R, Geller PA, Martin ML. Recommendations for enhancing psychosocial support of NICU parents through staff education and support. J Perinatol . 2015 Dec;35 Suppl 1:S29-36. doi: 10.1038/jp.2015.147.

Hynan MT, Steinberg Z, Baker L, Cicco R, Geller PA, Lassen S, Milford C, Mounts KO, Patterson C, Saxton S, Segre L, Stuebe A. Recommendations for mental health professionals in the NICU.  J Perinatol. 2015 Dec;35 Suppl 1:S14-8. doi: 10.1038/jp.2015.144.

Stoll BJ, Hansen NI, Bell EF, Walsh MC, Carlo WA, Shankaran S, Laptook AR, Sánchez PJ, Van Meurs KP, Wyckoff M, Das A, Hale EC, Ball MB, Newman NS, Schibler K, Poindexter BB, Kennedy KA, Cotten CM, Watterberg KL, D'Angio CT, DeMauro SB, Truog WE, Devaskar U, Higgins RD; Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. Trends in Care Practices, Morbidity, and Mortality of Extremely Preterm Neonates. JAMA. 2015 Sep 8;314(10):1039-1051. doi: 10.1001/jama.2015.10244.

Jensen EA, Lorch SA. Effects of a Birth Hospital's Neonatal Intensive Care Unit Level and Annual Volume of Very Low-Birth-Weight Infant Deliveries on Morbidity and Mortality. JAMA Pediatr . 2015 Aug 3;169(8):e151906. doi: 10.1001/jamapediatrics.2015.1906. Epub 2015 Aug 3. PMID: 26237466

Guaman MC, Gien J, Baker CD, Zhang H, Austin ED, Collaco JM. Point Prevalence, Clinical Characteristics, and Treatment Variation for Infants with Severe Bronchopulmonary Dysplasia. Am J Perinatol . 2015 Aug;32(10):960-7. doi: 10.1055/s-0035-1547326. Epub 2015 Mar 4. PMID: 25738785.

Foglia EE, Nolen TL, DeMauro SB, Das A, Bell EF, Stoll BJ, Schmidt B; Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. Short-term Outcomes of Infants Enrolled in Randomized Clinical Trials vs Those Eligible but Not Enrolled. JAMA . 2015 Jun 16;313(23):2377-2379. doi: 10.1001/jama.2015.5734. No abstract available. PMID: 26080344

Tucker Edmonds B, Mckenzie F, Macheras M, Srinivas SK, Lorch SA. Morbidity and mortality associated with mode of delivery for breech periviable deliveries. Am J Obstet Gynecol. 2015 Mar 3. pii: S0002-9378(15)00196-9. doi: 10.1016/j.ajog.2015.03.002. [Epub ahead of print] PMID: 25747545 

Bamat N, Ghavam S, Liu Y, DeMauro SB, Jensen EA, Roberts R, Yoder BA, Kirpalani H. Reliability of a Non-Invasive Measure of Ventilation/Perfusion Mismatch for Bronchopulmonary Dysplasia. Ann Am Thorac Soc . 2015 Feb 25. [Epub ahead of print] PubMed PMID: 25714998.

Kemper AR1, Wade KC2, Hornik CP3, Ying GS4, Baumritter A5, Quinn GE5; Telemedicine Approaches to Evaluating Acute-phase Retinopathy of Prematurity (e-ROP) Study Cooperative Group. Retinopathy of prematurity risk prediction for infants with birth weight less than 1251 grams. J Pediatr . 2015 Feb;166(2):257-261.e2. doi: 10.1016/j.jpeds.2014.09.069. Epub 2014 Nov 12. Read the abstract . 

Lorch SA. The Clinical and Policy Implications of New Measures of Premature Infant Growth. Pediatrics . 2015 Feb 16. pii: peds.2014-3774. [Epub ahead of print]

Jensen EA, DeMauro SB, Kornhauser M, Aghai ZH, Greenspan JS, Dysart KC. Effects of multiple ventilation courses and duration of mechanical ventilation on respiratory outcomes in extremely low-birth-weight infants. JAMA Pediatr. 2015 Nov;169(11):1011-7. doi: 10.1001/jamapediatrics.2015.2401.

Jensen EA, Foglia EE, Schmidt B. Evidence-based pharmacological therapies for prevention of bronchopulmonary dysplasia: Application of the Grading of Recommendations Assessment, Development and Evaluation (GRADE) methodology. Clin Perinatol. 2015;42(4):755-79.

Pulmonary hypertension in giant omphalocele infants. Partridge EA, Hanna BD, Panitch HB, Rintoul NE, Peranteau WH, Flake AW, Scott Adzick N, Hedrick HL.J Pediatr Surg. 2014 Dec;49(12):1767-70. doi: 10.1016/j.jpedsurg.2014.09.016. Epub 2014 Nov 14.PMID: 25487480

Fetal myelomeningocele repair: the post-MOMS experience at the Children's Hospital of Philadelphia. Moldenhauer JS, Soni S, Rintoul NE, Spinner SS, Khalek N, Martinez-Poyer J, Flake AW, Hedrick HL, Peranteau WH, Rendon N, Koh J, Howell LJ, Heuer GG, Sutton LN, Johnson MP, Adzick NS.Fetal Diagn Ther. 2015;37(3):235-40. doi: 10.1159/000365353. Epub 2014 Aug 15.PMID: 25138132

Lung function over the first 3 years of life in children with congenital diaphragmatic hernia. Panitch HB, Weiner DJ, Feng R, Perez MR, Healy F, McDonough JM, Rintoul N, Hedrick HL. Pediatr Pulmonol. 2015 Sep;50(9):896-907. doi: 10.1002/ppul.23082. Epub 2014 Jul 10.PMID: 25045135

Safety of epoprostenol and treprostinil in children less than 12 months of age. McIntyre CM, Hanna BD, Rintoul N, Ramsey EZ. Pulm Circ. 2013 Dec;3(4):862-9. doi: 10.1086/674762.PMID: 25006402 Free PMC article.

Incidence and factors associated with sensorineural and conductive hearing loss among survivors of congenital diaphragmatic hernia. Partridge EA, Bridge C, Donaher JG, Herkert LM, Grill E, Danzer E, Gerdes M, Hoffman CH, D'Agostino JA, Bernbaum JC, Rintoul NE, Peranteau WH, Flake AW, Adzick NS, Hedrick HL.J Pediatr Surg. 2014 Jun;49(6):890-4; discussion 894. doi: 10.1016/j.jpedsurg.2014.01.019. Epub 2014 Jan 31.PMID: 24888829

Marcus CL, Meltzer LJ, Roberts RS, Traylor J, Dix J, D'ilario J, Asztalos E, Opie G, Doyle LW, Biggs SN, Nixon GM, Narang I, Bhattacharjee R, Davey M, Horne RS, Cheshire M, Gibbons J, Costantini L, Bradford R, Schmidt B; Caffeine for Apnea of Prematurity–Sleep Study. Long-term effects of caffeine therapy for apnea of prematurity on sleep at school age. Am J Respir Crit Care Med . 2014 Oct 1;190(7):791-9. Read the abstract .

Schmidt B, Roberts RS, Whyte RK, Asztalos EV, Poets C, Rabi Y, Solimano A, Nelson H; Canadian Oxygen Trial Group. Impact of study oximeter masking algorithm on titration of oxygen therapy in the Canadian oxygen trial. J Pediatr . 2014 Oct;165(4):666-71.e2. doi: 10.1016/j.jpeds.2014.05.028. Epub 2014 Jun 25. PMID: 24973289. Read the abstract . 

Shankaran S, Laptook AR, Pappas A, McDonald SA, Das A, Tyson JE, Poindexter BB, Schibler K, Bell EF, Heyne RJ, Pedroza C, Bara R, Van Meurs KP, Grisby C, Huitema CM, Garg M, Ehrenkranz RA, Shepherd EG, Chalak LF, Hamrick SE, Khan AM, Reynolds AM, Laughon MM, Truog WE, Dysart KC, Carlo WA, Walsh MC, Watterberg KL, Higgins RD; Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. Effect of depth and duration of cooling on deaths in the NICU among neonates with hypoxic ischemic encephalopathy: a randomized clinical trial. JAMA . 2014 Dec 24-31;312(24):2629-39. doi: 10.1001/jama.2014.16058. Read the abstract .

Tran PV, Kennedy BC, Lien YC, Simmons RA, Georgieff MK. Fetal iron deficiency induces chromatin remodeling at the Bdnf locus in adult rat hippocampus. Am J Physiol Regul Integr Comp Physiol. 2014 Dec 17:ajpregu.00429.2014. doi: 10.1152/ajpregu.00429.2014. [Epub ahead of print]. Read the abstract .

Massaro AN, Murthy K, Zaniletti I, Cook N, DiGeronimo R, Dizon M, Hamrick SE, McKay VJ, Natarajan G, Rao R, Smith D, Telesco R, Wadhawan R, Asselin JM, Durand DJ, Evans JR, Dykes F, Reber KM, Padula MA, Pallotto EK, Short BL, Mathur AM. Short-term outcomes after perinatal hypoxic ischemic encephalopathy: a report from the Children's Hospitals Neonatal Consortium HIE focus group. J Perinatol. 2014 Nov 13. doi: 10.1038/jp.2014.190. [Epub ahead of print]. Read the abstract .

Lorch SA. Ensuring Access to the Appropriate Healthcare Professionals: Regionalization and Centralization of Care in a New Era of Healthcare Financing and Delivery. JAMA Pediatr. 2014 Nov 10. doi: 10.1001/jamapediatrics.2014.2468. [Epub ahead of print]

Posencheg M, Kirpalani H. Placental Transfusion at Birth: Do We Have All of the Answers?. JAMA Pediatr . 2014 Nov 3. doi: 10.1001/jamapediatrics.2014.2347. [Epub ahead of print]

Jensen EA, DeMauro SB, Kirpalani H. Has enough evidence accumulated to consider CPAP a first-line standard of care in developing countries? Arch Dis Child Fetal Neonatal Ed. 2014 Nov;99(6):F443-4. doi: 10.1136/archdischild-2014-305991. Epub 2014 Aug 18.

Padula, MA; Dewan, ML; Shah, SS; Padula, AM; Srinivasan, L; McGowan, KL; Mahoney, KR; Harris, MC. Risk Factors Associated with Laboratory-confirmed Bloodstream Infections in a Tertiary Neonatal Intensive Care Unit. Pediatr Infect Dis J. 2014 Oct. 33 (10):1027-1032. Read the abstract .

Lorch SA, Passarella M, Zeigler A. Challenges to measuring variation in readmission rates of neonatal intensive care patients. Acad Pediatr. 2014 Sep-Oct;14(5 Suppl):S47-53. doi: 10.1016/j.acap.2014.06.010. Read the abstract .

Nakamura MM, Toomey SL, Zaslavsky AM, Berry JG, Lorch SA, Jha AK, Bryant MC, Geanacopoulos AT, Loren SS, Pain D, Schuster MA. Measuring Pediatric Hospital Readmission Rates to Drive Quality Improvement. Acad Pediatr. 2014 Sep-Oct;14(5 Suppl):S39-46. doi: 10.1016/j.acap.2014.06.012. Read the abstract .

Jensen EA, Kirpalani H. Inhaled Nitric Oxide to Prevent Bronchopulmonary Dysplasia in Preterm Infants-Less than a Silver Bullet. J Pediatr. 2014 Sep 27. pii: S0022-3476(14)00787-2. doi: 10.1016/j.jpeds.2014.08.040. [Epub ahead of print] No abstract available.

Lemyre B, Davis PG, De Paoli AG, Kirpalani H. Nasal intermittent positive pressure ventilation (NIPPV) versus nasal continuous positive airway pressure (NCPAP) for preterm neonates after extubation. Cochrane Database Syst Rev. 2014 Sep 4;9:CD003212. [Epub ahead of print] Read the abstract .

Marcus CL, Meltzer LJ, Roberts RS, Traylor J, Dix J, D'ilario J, Asztalos E, Opie G, Doyle LW, Biggs SN, Nixon GM, Narang I, Bhattacharjee R, Davey M, Horne RS, Cheshire M, Gibbons J, Costantini L, Bradford R, Schmidt B; for the Caffeine for Apnea of Prematurity – Sleep (CAP-S) study. Long-term Effects of Caffeine Therapy for Apnea of Prematurity on Sleep at School-age. Am J Respir Crit Care Med. 2014 Aug 29. [Epub ahead of print] Read the abstract .

Biswas C, Shah N, Muthu M, La P, Fernando AP, Sengupta S, Yang G, Dennery PA. Nuclear Heme Oxygenase-1 (HO-1) Modulates Subcellular Distribution and Activation of Nrf2 Impacting Metabolic and Anti-oxidant Defenses. J Biol Chem . 2014 Aug 8. pii: jbc.M114.567685. [Epub ahead of print]. Read the abstract .

Grover TR, Brozanski BS, Barry J, Zaniletti I, Asselin JM, Durand DJ, Short BL, Pallotto EK, Dykes F, Reber KM, Padula MA, Evans JR, Murthy K. High surgical burden for infants with severe chronic lung disease (sCLD). J Pediatr Surg. 2014 Aug;49(8):1202-5. Read the abstract .

Murthy K, Evans JR, Bhatia AM, Rothstein DH, Wadhawan R, Zaniletti I, Rao R, Thurm C, Mathur AM, Piazza AJ, Stein JE, Reber KM, Short BL, Padula MA, Durand DJ, Asselin JM, Pallotto EK, Dykes FD. The association of type of surgical closure on length of stay among infants with gastroschisis born≥34weeks' gestation. J Pediatr Surg. 2014 Aug;49(8):1220-5. Epub 2014 Jan 2. Read the abstract .

DeMauro SB, Cairnie J, D’Ilario J, Kirpalani H, Schmidt B. Honesty, Trust, and Respect During Consent Discussions in Neonatal Clinical Trials. Pediatrics. 2014 Jul;134(1):e1-3. Epub 2014 Jun 9. Read the abstract .

Shelton E, Ector G, Galindo C, Hooper C, Brown N, Wilkerson I, Pfaltzgraff E, Paria B, Cotton R, Stoller JZ, Reese J: Transcriptional profiling reveals ductus arteriosus-specific genes that regulate vascular tone. Physiol Genomics. 2014 Jul 1;46(13):457-66. Epub 2014 May 1. Read the abstract .

Schmidt B, Roberts RS, Whyte RK, Asztalos EV, Poets C, Rabi Y, Solimano A, Nelson H; Canadian Oxygen Trial Group. Impact of Study Oximeter Masking Algorithm on Titration of Oxygen Therapy in the Canadian Oxygen Trial. J Pediatr. 2014 Jun 25. pii: S0022-3476(14)00455-7. [Epub ahead of print]. Read the abstract.

Monk HM, Motsney AJ, Wade KC. Safety of Rotavirus Vaccine in the NICU. J Pediatr. 2014 May 19. [Epub ahead of print]. Read the abstract .

Foglia EE, Kirpalani H, DeMauro SB. Long-Term Respiratory Morbidity in Preterm Infants: Is Noninvasive Support in the Delivery Room the Solution? J Pediatr. 2014 May 16. pii: S0022-3476(14)00347-3. doi: 10.1016/j.jpeds.2014.04.018. [Epub ahead of print] Read the abstract .

Ghavam S, Batra D, Mercer J, Kugelman A, Hosono S, Oh W, Rabe H, Kirpalani H. Effects of placental transfusion in extremely low birthweight infants: meta-analysis of long- and short-term outcome. Transfusion. 2014 Apr;54(4):1192-8. Read the abstract .

Jensen EA, Munson DA, Zhang H, Blinman TA, Kirpalani H. Anti-gastroesophageal reflux surgery in infants with severe bronchopulmonary dysplasia. Pediatr Pulmonol. Epub 2014 Apr 21.  Read the abstract .

McKenna S, Michaelis KA, Agboke F, Liu T, Han K, Yang G, Dennery PA, Wright CJ. Sustained hyperoxia-induced NFkB activation improves survival and preserves lung development in neonatal mice. Am J Physiol Lung Cell Mol Physiol. Epub 2014 Apr 18.  Read the abstract .

Schmidt B, Whyte RK, Roberts RS. Trade-off between lower or higher oxygen saturations for extremely preterm infants: The first benefits of oxygen saturation targeting (BOOST) II trial reports its primary outcome. J Pediatr. Epub 2014 Apr 11.  Read the abstract .

Murthy K, Savani RC, Lagatta JM, Zaniletti I, Wadhawan R, Truog W, Grover TR, Zhang H, Asselin JM, Durand DJ, Short BL, Pallotto EK, Padula MA, Dykes FD, Reber KM, Evans JR. Predicting death or tracheostomy placement in infants with severe bronchopulmonary dysplasia. J Perinatol. Epub 2014 Mar 20.  Read the abstract .

Schmidt B, Davis PG, Roberts RS. Timing of caffeine therapy in very low birth weight infants . J Pediatr. 2014 May;164(5):957-8. doi: 10.1016/j.jpeds.2014.01.054. Epub 2014 Mar 12. Abstract not available.

Murthy K, Dykes FD, Padula MA, Pallotto EK, Reber KM, Durand DJ, Short BL, Asselin JM, Zaniletti I, Evans JR. The Children’s Hospitals Neonatal Database: An overview of patient complexity, outcomes and variation in care. J Perinatol. Epub 2014 Mar 6.  Read the abstract .

Giaccone A, Jensen EA, Davis P, Schmidt B. Definitions of extubation success in preterm infants: A systematic review. Arch Dis Child Fetal Neonatal Ed. 2014 Mar;99(2):F124-7. doi: 10.1136/archdischild-2013-304896. Epub 2013 Nov 18.

Taha D, Kirkby S, Nawab U, Dysart KC, Genen L, Greenspan JS, Aghai ZH. Early caffeine therapy for prevention of bronchopulmonary dysplasia in preterm infants. J Matern Fetal Neonatal Med. Epub 2014 Feb 17.  Read the abstract .

Sawyer T, French H, Soghier L, Barry J, Johnston L, Anderson J, Ades A. Educational Perspectives: Boot Camps for Neonatal-Perinatal Medicine Fellows. NEOREVIEWS Vol. 15 No. 2 February 1, 2014. pp. e46 -e55. doi: 10.1542/neo.15-2-e46.

DeMauro SB, D'Agostino JA, Bann C, Bernbaum J, Gerdes M, Bell EF, Carlo WA, D'Angio CT, Das A, Higgins R, Hintz SR, Laptook AR, Natarajan G, Nelin L, Poindexter BB, Sanchez PJ, Shankaran S, Stoll BJ, Truog W, Van Meurs KP, Vohr B, Walsh MC, Kirpalani H, Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. Developmental Outcomes of Very Preterm Infants with Tracheostomies. J Pediatr. 2014 Epub Jan 25. pii: S0022-3476(13)01560-6. doi: 10.1016/j.jpeds.2013.12.014.  Read the abstract .

Murthy K, Evans JR, Bhatia A, Rothstein D, Wadwahan R, Zaniletti I, Rao R, Thurm C, Mathur A, Piazza AJ, Stein JE, Reber KM, Short BL, Padula MA, Durand DJ, Asselin JM, Pallotto EK, Dykes FD. The Association of Type of Closure on LOS for infants with Gastroschisis born ≥ 34 weeks’ Gestation. J Pediatr Surg. 2014 in press. Epub ahead of print 2014 Jan 06.  Read the abstract .

Giaccone A, Jensen E, Davis P, Schmidt B. Definitions of extubation success in very premature infants: a systematic review. Arch Dis Child Fetal Neonatal Ed. 2014;99(2):F124–127.  Read the abstract .

Kahn MG, Bailey LC, Forrest CB, Padula MA, Hirschfeld S. Building a common pediatric research terminology for accelerating child health research. Pediatrics. 2014;133(3):516-525.  Read the abstract .

Schmidt B, Davis PG, Asztalos EV, Solimano A, Roberts RS. Association between severe retinopathy of prematurity and nonvisual disabilities at age 5 years. JAMA. 2014;311(5):523-525.

Jensen EA, Schmidt B. Epidemiology of bronchopulmonary dysplasia. Birth Defects Res A Clin Mol Teratol. 2014;100(3):145-157.

Danzer E, Gerdes M, D'Agostino JA, Hoffman C, Bernbaum J, Bebbington MW, Siegle J, Sulkowski J, Rintoul NE, Flake AW, Scott Adzick N, Hedrick HL.J Perinatol. Longitudinal neurodevelopmental and neuromotor outcome in congenital diaphragmatic hernia patients in the first 3 years of life. 2013 Nov;33(11):893-8. doi: 10.1038/jp.2013.47. Epub 2013 May 9.PMID: 23660581

DeMauro SB, Cohen MS, Ratcliffe SJ, Abbasi S, Schmidt B. Serial echocardiography in very preterm infants: a pilot randomized trial. Acta Paediatr. 2013 Nov;102(11):1048-53. Epub 2013 Sep 13. Read the abstract.

Cheng J, Lioy J, Sobol S. Effect of tracheostomy timing in premature infants. Int J Pediatr Otorhinolaryngol. 2013 Nov;77(11):1873-6. doi: 10.1016/j.ijporl.2013.08.032. Epub 2013 Sep 5. Read the abstract.

Sherenian M, Profit J, Schmidt B, Suh S, Xiao R, Zupancic JA, DeMauro SB. Nurse-to-patient ratios and neonatal outcomes: a brief systematic review. Neonatology. 2013;104(3):179-83. Epub 2013 Aug 8. Review. Read the abstract.

Flibotte JJ, Lee GE, Buser GL, Feja KN, Kreiswirth BN, McSherry GD, Nolan SM, Rolan RW Jr., Shang H. (2013) Infertility, in vitro fertilization and congenital tuberculosis. J Perinatol. 2013;33(7):565-568. Read the abstract.

Hackman DA, Betancourt LM, Brodsky NL, Kobrin L, Hurt H, Farah MJ. (2013) Selective impact of early parental responsivity on adolescent stress reactivity. PLoS One. 2013;8(3):e58250. doi: 10.1371/journal.pone.0058250. Epub 2013 Mar 13. Read the abstract.

Khurana, A, Romer, D, Betancourt, LM, Brodsky, NL, Giannetta, JM, & Hurt, H. Working memory ability predicts trajectories of early alcohol use in adolescents: The mediational role of impulsivity. Addiction. 2013 Mar;108(3):506-15. doi: 10.1111/add.12001. Epub 2012 Nov 1. Read the abstract. 

La P, Dennery PA. Mammalian target of rapamycin complex 1 (mTORC1)-mediated phosphorylation stabilizes ISCU protein: Implications for iron metabolism. J Biol Chem. 2013; 288(18):12901-12909. Epub 2013 March. Read the abstract.

Lorch SA. Quality measurements in pediatrics: what do they assess? JAMA Pediatr. 2013;167(1):89-90. Read the article. 

Sullivan KM, Suh S, Monk H, Chuo J. Personalised performance feedback reduces narcotic prescription errors in a NICU. BMJ Qual Saf. 2013 Mar;22(3):256-62. doi: 10.1136/bmjqs-2012-001089. Epub 2012 Oct 4. Read the abstract.

Sivieri EM, Gerdes JS, Abbasi S. Effect of HFNC flow rate, cannula size, and nares diameter on generated airway pressures: An in vitro study. Pediatr Pulmonol. 2013 May;48(5):506-14. doi: 10.1002/ppul.22636. Epub 2012 Jul 23. Read the abstract.

Simmons RA. Developmental Origins of Diabetes: The Role of Oxidative Stress. Free Radic Biol Med. 2006 Mar 15;40(6):917-22. Epub 2006 Jan 13. Read the abstract. 

Simmons RA. Preclampsia and prematurity as precursors to adolescent obesity. J Pediatr. 2013 Feb 14. pii: S0022-3476(13)00040-1. doi: 10.1016/j.jpeds.2013.01.016. [Epub ahead of print] Read the abstract. 

Simmons RA. Programming of DNA methylation in type 2 diabetes. Diabetologia. 2013 May;56(5):947-8. doi: 10.1007/s00125-013-2866-4. Epub 2013 Mar 6. Read the abstract.

Gatford KL, Sulaiman SA, Mohammad SNB, De Blasio MJ, Harland ML, Simmons RA*, Owens JA*. Neonatal exendin-4 treatment reduces growth, fat deposition and glucose tolerance during treatment in the intrauterine growth-restricted lamb. PLoS One. 2013;8(2):e56553. doi: 10.1371/journal.pone.0056553. Epub 2013 Feb 12. * Co-senior authors. Read the abstract.

Preschool neurological assessment in congenital diaphragmatic hernia survivors: outcome and perinatal factors associated with neurodevelopmental impairment. Danzer E, Gerdes M, D'Agostino JA, Partridge EA, Hoffman-Craven CH, Bernbaum J, Rintoul NE, Flake AW, Adzick NS, Hedrick HL.Early Hum Dev. 2013 Jun;89(6):393-400. doi: 10.1016/j.earlhumdev.2012.12.009. Epub 2013 Jan 17.PMID: 23333410

Assessment of early pulmonary function abnormalities in giant omphalocele survivors. Danzer E, Hedrick HL, Rintoul NE, Siegle J, Adzick NS, Panitch HB.J Pediatr Surg. 2012 Oct;47(10):1811-20. doi: 10.1016/j.jpedsurg.2012.06.006.PMID: 23084189

Fetal MRI-calculated total lung volumes in the prediction of short-term outcome in giant omphalocele: preliminary findings. Danzer E, Victoria T, Bebbington MW, Siegle J, Rintoul NE, Johnson MP, Flake AW, Adzick NS, Hedrick HL.Fetal Diagn Ther. 2012;31(4):248-53. doi: 10.1159/000334284. Epub 2012 Apr 27.PMID: 22572017 Review.

Early neurodevelopmental outcome of infants with high-risk fetal lung lesions. Danzer E, Siegle J, D'Agostino JA, Gerdes M, Hoffman C, Bernbaum J, Rintoul NE, Flake AW, Adzick NS, Hedrick HL.Fetal Diagn Ther. 2012;31(4):210-5. doi: 10.1159/000336228. Epub 2012 Apr 26.PMID: 22539010 Free article.

Srinivasan L, Harris MC, Shah SS. Lumbar puncture in the neonate: challenges in decision making and interpretation. Semin Perinatol. 2012 Dec;36(6):445-53. doi: 10.1053/j.semperi.2012.06.007. Read the abstract.

Abbasi S, Sivieri E, Roberts R, Kirpalani H. Accuracy of tidal volume, compliance and resistance measurements on neonatal ventilator displays: an in vitro assessment. Pediatr Crit Care Med. 2012, May 16. 13:e262–268. [Epub ahead of print] Read the abstract.

Anagnostis EA, Sadaka RE, Sailor LA, Moody DE, Dysart KC, Kraft WK. Formulation of buprenorphine for sublingual use in neonates. J Pediatr Pharmacol Ther. 2011 Oct;16(4):281-4. Read the abstract. 

Begany, M. Identification of fracture risk and strategies for bone health in the neonatal intensive care unit. Top Clin Nutr. 2012;27(3):231-249. Abstract not available.

Bingham, E. Optimizing nutrition in the neonatal intensive care unit: a look at enteral nutrition and the prevention of necrotizing enterocolitis. Top Clin Nutr. 2012;27(3):250-259. Abstract not available.

DeMauro SB, Kilpatrick LE, Gerdes JS, Abbasi S. Early inflammatory markers for prediction of cholestasis in very low birth weight infants. Neonatology. 2012 Aug 15; 102(3): 229-234. [Epub ahead of print]. Read the article.

Dennis EF, Webb DA, Lorch SA, Mathew L, Bloch JR, Culhane JF. Subjective social status and maternal health in a low income urban population. Matern Child Health J. 2012 May;16(4):834-43. Read the abstract.

Dysart KC, Kirpalani HM, Kirpalani HM, Wusthoff CJ, Seshia SS. Amplitude-integrated electroencephalography: A runaway horse? Can J Neurol Sci. 2012 May;39(3):267-8. Read the abstract.

Foglia E, Lorch SA. Clinical predictors of urinary tract infection in the Neonatal Intensive Care Unit. JNPM 2012; 5(4). Read the article. 

Giaccone A, Kirpalani H. Judgment often impossible without randomized trials. Neonatology 2012;102(2):137-138. Epub 2012 Jun 16. Read the article.

Giannetta M, Betancourt LM, Brodsky NL, Wintersteen MB, Romer D, Giannetta JM, Hurt H. Suicidal ideation and self-harm behavior in a community sample of preadolescent youth: A case-control study. J Adolesc Health. May 2012; 50(5):524-526. Read the article.  

Gollomp K, Rankin C, White SC, Mattei P, Harris MC, Kilpatrick L, Sheffler-Collins S, McGowan KL, Shah SS. Broad-range bacterial PCR in the microbiologic diagnosis of complicated pneumonia. J Hosp Med. 2011 Oct 12. doi: 10.1002/jhm.911. [Epub ahead of print] Read the abstract.

Goyal N, Fiks A, Lorch SA. Persistence of underweight status among late preterm infants. Arch Pediatr Adolesc Med. 2012 May;166(5):424-30. Read the article.

Guillén U, DeMauro SB, Ma L, Zupancic J, Roberts RS, Schmidt B, Kirpalani H. Relationship between attrition and neurodevelopmental impairment rates of extremely preterm or extremely low birth weight infants at 18-24 months: A systematic review. Arch Pediatr Adolesc Med. 2012 Feb;166(2):178-84. Read the abstract.

Guillen U, Suh S, Munson D, Posencheg M, Truitt E, Zupancic J, Gafni A, Kirpalani H. The development and pre-testing of a decision-aid to use when counseling parents facing imminent extreme premature delivery. J Pediatr. 2012 Mar;160(3):382-7. Epub 2011 Nov 1. Read the abstract.

Handzel JM, Brodsky N, Betancourt L, Hurt H. Longitudinal follow-up of poor inner-city youth between ages 8 and 18: Intentions versus reality. Pediatrics. 2012 Mar;129(3):473-9. Epub 2012 Feb 20. Read the abstract.

Hsu Y, Lorch SA, Small D. Perils and prospects of using aggregate area level socioeconomic information as a proxy for individual level socioeconomic confounders in instrumental variables regression. Hlth Serv Outcomes Res Methodol 12(2-3): 119-140, 2012. Read the article.

Jain V, Duda J, Avants B, Giannetta M, Xie SX, Roberts T, Detre JA, Hurt H, Wehrli FW, Wang DJ. Longitudinal reproducibility and accuracy of pseudo-continuous arterial spin-labeled perfusion MR imaging in typically developing children. Radiology. 2012 May;263(2):527-36. Read the abstract.

Kamholz KI, Dukhovny D, Kirpalani H, Whyte RK, Roberts RS, Wang N, Mao WY, Zupancic JAF, and the Premature Infants in Need of Transfusion Study Group. Economic evaluation alongside the premature infants in need of transfusion (PINT) randomized controlled trial. Arch Dis Child Fetal Neonatal Ed. 2012 Mar;97(2):F93-8. Epub 2011 Jul 6. Read the abstract. 

Khurana A, Romer D, Betancourt LM, Brodsky NL, Giannetta JM, Hurt H. Early adolescent sexual debut: The mediating role of working memory ability, sensation-seeking and impulsivity. Dev Psychol. 2012 Sep;48(5):1416-28. doi: 10.1037/a0027491. Epub 2012 Feb 27. Read the abstract. 

Kirpalani H, Zupancic JA. Do transfusions cause necrotizing enterocolitis? The complementary role of randomized trials and observational studies. Semin Perinatol. 2012 Aug;36(4):269-76. doi: 10.1053/j.semperi.2012.04.007. Read the abstract.

Lorch SA. Neonatology enters the 21st century for healthcare oversight: The public reporting of healthcare outcomes. J Perinatol. 2012 Apr;32(4):245-6. doi: 10.1038/jp.2012.13. Read the abstract.

Lorch SA, Baiocchi M, Ahlberg CE, Small, DS. The differential impact of delivery hospital on the outcomes of premature infants. Pediatrics. 2012 Aug;130(2):270-8. Epub 2012 Jul 9.  Read the abstract.

Lorch SA, Kroelinger CD, Ahlberg C, Barfield WD. Factors that mediate racial/ethnic disparities in U.S. fetal death rates. Am J Public Health. 2012 Oct;102(10):1902-10. doi: 10.2105/AJPH.2012.300852. Epub 2012 Aug 16. Read the abstract.

Lorch SA, Maheshwari P, Even-Shoshan O. The impact of certificate of need programs on neonatal intensive care units. J Perinatol. 2012 Jan;32(1):39-44. doi: 10.1038/jp.2011.47. Epub 2011 Apr 28. Read the abstract.

Lorch SA, Srinivas SK, Ahlberg C, Small DS. The impact of obstetric unit closures on maternal and infant pregnancy outcomes. Health Serv Res. 2012 Aug 10. [Epub ahead of print] Read the abstract.

Mantegazza AR, Guttentag S, Sasai M, Iwasaki A, Shen H, Laufer TM, Marks M. Adaptor protein-3 in dendritic cells facilitates phagosomal toll-like receptor signaling and antigen presentation to CD4+ T cells. Immunity. 2012 May 25;36(5):782-94. Epub 2012 May 3. Read the abstract.

Mossabeb R, Wade K, Finnegan K, Sivieri E, Abbasi S. Language development survey provides a useful screening tool for language delay in preterm infants. Clin Pediatr (Phila). 2012 Jul;51(7):638-44. Epub 2012 Mar 7. Read the abstract.

Patel J, Posencheg M, Ades A. Proficiency and retention of neonatal resuscitation skills by pediatric residents. Pediatrics. 2012 Sep;130(3):515-21. Epub 2012 Aug 27. Read the abstract.

Pati S, Lorch S, Lee GE, Sheffler-Collins S, Shah S. Health insurance and length of stay for children hospitalized with community-acquired pneumonia. J Hosp Med. 2012 Apr;7(4):304-10. doi: 10.1002/jhm.959. Epub 2011 Oct 3. Read the abstract.

Phalen AG, Kirkby S, Dysart K. The 5-minute apgar score: Survival and short-term outcomes in extremely low-birth-weight infants. J Perinat Neonatal Nurs. 2012 Apr;26(2):166-71. Read the abstract.

Pinney SE, Simmons R. Metabolic programming, epigenetics, and gestational diabetes mellitus. Curr Diab Rep. 2012 Feb;12(1):67-74. Read the abstract.

Posencheg MA, Dennery PA. Hemolytic disease of the fetus and newborn. Conn’s Current Therapy, 2012, Section 20, Children’s Health, pp. 1079-1083.

Rausch M, Lorch S, Chung K, Frederick M, Zhang J, Barnhart K. A cost-effectiveness analysis of surgical versus medical management of early pregnancy loss. Fertil Steril. 2012 Feb;97(2):355-60. Epub 2011 Dec 21. Read the abstract.

Ray KN, Lorch SA. Hospitalization of rural and urban infants during the first year of life. Pediatrics. 2012 Dec;130(6):1084-93. doi: 10.1542/peds.2012-0020. Epub 2012 Nov 5. Read the abstract. 

Reid MV, Murray KA, Marsh ED, Golden JA, Simmons RA*, Grinspan JB *. Delayed myelination in an intrauterine growth retardation model is mediated by oxidative stress upregulating bone morphogenetic protein 4. J Neuropathol Exp Neurol. 2012 Jul;71(7):640-53. * Co-senior author. Read the abstract.

Reiss E, Lasker BA, Lott TJ, Bendel CM, Kaufman DA, Hazen KC, Wade KC, McGowan KL, Lockhart SR. Genotyping of Candida parapsilosis from three neonatal intensive care units (NICUs) using a panel of five multilocus microsatellite markers: Broad genetic diversity and a cluster of related strains in one NICU. Infect Genet Evol. 2012 Jul 5. [Epub ahead of print] Read the abstract.

Schmidt B, Anderson PJ, Doyle LW, Dewey D, Grunau RE, Asztalos EV, Davis PG, Tin W, Moddemann D, Solimano A, Ohlsson A, Barrington KJ, Roberts RS; Caffeine for Apnea of Prematurity (CAP) Trial Investigators. Survival without disability to age 5 years after neonatal caffeine therapy for apnea of prematurity. JAMA. 2012 Jan 18;307(3):275-82. Read the abstract.

Sivieri E, MS1, Gerdes, Abbasi S: Effect of High Flow Nasal Cannula flow rate and cannula size on generated airway pressures: An in-vitro study. Pediatr Pulmonol. 2012 Jul 23. doi: 10.1002/ppul.22636. [Epub ahead of print]  Read the abstract.

Srinivasan L, Harris MC. New technologies for the rapid diagnosis of neonatal sepsis. Curr Opin Pediatr. 2012 Apr;24(2):165-71. Read the abstract.

Srinivasan L, Harris MC, Shah SS. Lumbar puncture in the neonate: challenges in decision-making and interpretation. Semin Perinatol. 2012 Dec;36(6):445-53. doi: 10.1053/j.semperi.2012.06.007. Read the abstract.

Srinivasan L, Shah S, Padula M, Abbasi S, McGowan K, Harris M. Cerebrospinal fluid reference ranges in term and preterm infants in the neonatal intensive care unit. J Pediatr. 2012 May 9. [Epub ahead of print] Read the abstract.

Srinivasan L, Shah SS, Padula MA, Abbasi S, McGowan KL, Harris MC. Reference Ranges for Cerebrospinal Fluid (CSF) Parameters in Term and Preterm Infants in the Neonatal Intensive Care Unit. J Pediatr 2012;161(4):729-34.4. Abstract not available.

Srinivas SK, Shocksnider J, Caldwell D, Lorch S: Laborist model of care: Who is using it? J Matern Fetal Neonatal Med. 2012 Mar;25(3):257-60. Epub 2011 Apr 20. Read the abstract.

Srinivasan L, Pisapia JM, Shah SS, Halpern CH, Harris MC. Can broad-range 16S ribosomal ribonucleic acid gene polymerase chain reactions improve the diagnosis of bacterial meningitis? A systematic review and meta-analysis. Ann Emerg Med. 2012 Aug 7. [Epub ahead of print]  Read the abstract.

Stoller JZ, DeMauro SB, Dagle JM, Reese J. Current perspectives on pathobiology of the Ductus Arteriosus. Journal of Clinical and Experimental Cardiology. April 2012. Read the article.

Swarr DT, Kaufman B, Fogel MA, Finkel R, Ganesh J. Unusual cardiac "masses" in a newborn with infantile pompe disease. JIMD Reports. 2012 (5), 17-20. Abstract not available.

Tehrani F, Abbasi S: A model-based decision support system for critiquing mechanical ventilation treatments. J Clin Monit Comput. 2012 Jun;26(3):207-15. Epub 2012 Apr 25. Read the abstract.

Watt KM, Benjamin DK Jr, Cheifetz IM, Moorthy G, Wade KC, Smith PB, Brouwer KL, Capparelli EV, Cohen-Wolkowiezr M. Pharmacokinetics and safety of fluconazole in young infants supported with extracorporeal membrane oxygenation. Pediatr Infect Dis J. 2012 May 23. [Epub ahead of print] Read the abstract.

Wright CJ, Posencheg MA. Newborn Jaundice. Schwartz’s Clinical Handbook of Pediatrics, 5th Edition, 2012, Chapter 46, pp. 485-503.

Adzick NS, Thom EA, Spong CY, Brock JW 3rd, Burrows PK, Johnson MP, et al. A randomized trial of prenatal versus postnatal repair of myelomeningocele. N Engl J Med. 2011 Mar 17;364(11):993-1004. Epub 2011 Feb 9. Cited in PubMed; PMID 21306277. Read the article.

Anagnostis EA, Sadaka RE, Sailor LA, Moody DE, Dysart KC, Kraft WK. Formulation of buprenorphine for sublingual use in neonates. J Pediatr Pharmacol Ther. 2011 Oct;16(4):281-4. Read the abstract.

Atochina-Vasserman E, Bates S, Zhang P, Abramova H, Zhang Z, Gonzales L, et al. Early alveolar epithelial dysfunction promotes lung inflammation in a mouse model of Hermansky Pudlak syndrome. Am J Respir Crit Care Med. 2011 Aug 15;184(4):449-58. Cited in PubMed; PMID 2161998. Read the abstract.

Betancourt LM, Brodsky NL, Brown CA, McKenna KA, Giannetta JM, Yang W, et al. Is executive cognitive function associated with youth gambling? J Gambl Stud. Epub 2011 Jun 23. Cited in PubMed; PMID 21698342. Read the abstract.

Betancourt LM, Yang W, Brodsky NL, Gallagher PR, Malmud EK, Giannetta JM, et al. Adolescents with and without gestational cocaine exposure: Longitudinal analysis of inhibitory control, memory and receptive language. Neurotoxicol Teratol. 2011 Jan-Feb; 33(1):36-46. Cited in PubMed; PMID 21256423. Read the abstract.

Binenbaum G, Ying GS, Quinn GE, Dreiseitl S, Karp K, Roberts RS, et al. A clinical prediction model to stratify retinopathy of prematurity risk using postnatal weight gain. Pediatrics. 2011 Mar;27(3):e607-14. Epub 2011 Feb 14. Cited in PubMed; PMID 21321036. Read the abstract.

Calabria AC, Gallagher PR, Simmons R, Blinman T, DeLeon DD. Postoperative surveillance and detection of postprandial hypoglycemia after fundoplasty in children. J Pediatr. 2011 Oct;159(4):597-601.e1. Epub 2011 May 17. Read the abstract.

DeMauro SB, Abbasi S, Lorch S. The impact of feeding interval on feeding outcomes in very low birth-weight infants. J Perinatol. 2011 Jul;31(7):461-6. doi: 10.1038/jp.2010.153. Epub 2011 Jan 20. Cited in PubMed: PMID 21252961. Read the abstract.

DeMauro SB, Giaccone A, Kirpalani H, Schmidt B. Quality of reporting of neonatal and infant trials in high-impact journals. Pediatrics. Epub 2011 Aug 22. Cited in PubMed: PMID 21859916. Read the abstract.

DeMauro SB, Patel PR, Medoff Cooper B, Posencheg M, Abassi S . Postdischarge feeding patterns in early- and late-preterm infants. Clin Pediatr. 2011 Oct: 50(10): 957-62. Epub 2011 Aug 19. Read the abstract.

DeMauro SB, Roberts RS, Davis P, Alvaro R, Bairam A, Schmidt B, et al. Impact of delivery room resuscitation on outcomes up to 18 months in very low birth weight infants. J Pediatr. 2011 Oct 159(4):546-50.e1. Epub 2011 May 17. Cited in PubMed: PMID 21592510. Read the abstract.

DeMauro SB, Schmidt B, Roberts RS. Why would a sane clinician not prescribe prophylactic indomethacin? Acta Paediatr. 2011 May;100(5):636. doi: 10.1111/j.1651-2227.2011.02216.x. Epub 2011 mar 8. Cited in PubMed: PMID 21352363. Abstract not available.

Dennery PA. Introduction to the special issue on translational research involving oxidative stress. Free Radic Biol Med. 2011 Sep 1;51(5):923-4. Epub 2011 Jun 6. Cited in PubMed; PMID 21679766. Abstract not available.

Dennis EF, Webb DA, Lorch SA, Mathew L, Bloch JR, Culhand JF. Subjective social status and maternal health in a low income urban population. Matern Child Health J. Epub 2011 Apr 13. Cited in PubMed; PMID 21487843. Read the abstract.

Giaccone A, Kirpalani H. Judgment often impossible without randomized trials. Neonatology. 2012;102(2):137-138. Epub 2012 Jun 16. Read the abstract.

Guillen U, Demauro S, Ma L, Zupancic J, Wang E, Gafni A, et al. Survival rates in extremely low birthweight infants depend on the denominator: Avoiding potential for bias by specifying denominators. Am J Obstet Gynecol. Epub 2011 May 20. Cited in PubMed; PMID 2174613. Read the abstract.

Goyal NK, Fager C, Lorch SA. Adherence to discharge guidelines for late-preterm newborns. Pediatrics. 2011 Aug;128(2):e366-73. Epub 2011 Jul 11. Cited in PubMed; PMID 21746726. Read the abstract.

Jacobs SE, Morley CJ, Inder TE, Steward MJ, Smith KR, McNamara PJ, et al. Whole-body hypothermia for term and near-term newborns with hypoxic-ischemic encephalopathy: A randomized controlled trial. Arch Pediatr Adolesc Med. 2011 Aug;165(8):692-700. Epub 2011 Apr 4. Cited in PubMed; PMID 21464374. Read the abstract.

Kirpalani H, Whyte R. Truths, associations and hypotheses. J Pediatr. 2011 Sep;159(3):359-61. Epub 2011 Jun 16. Cited in PubMed; PMID 21679967. Abstract not available.

Kraft, Walter K, Dysart K, Greenspan JS, Gibson E, Kaltenbach K, Ehrlich ME. Revised dose schema of sublingual buprenorphine in the treatment of the neonatal opioid abstinence syndrome. Addiction. 2011 Mar;106(3):574-80. doi: 10.1111/j.1360-0443.2010.03170.x. Epub 2010 Oct 6. Read the article.

Liu Y, Mei J. Gonzales L, Yang G, Dai N, Wang P, et al. IL-17A and TNF-α exert synergistic effects on expression of CXCL5 by alveolar type II cells in vivo and in vitro. J Immunol. 2011 Mar 1;186(5):3197-205. Epub Jan 31. Cited in PubMed; PMID 21282514. Read the abstract.

Lorch SA, Maheshwari P, Even-Shoshan O. The impact of certificate of need programs on neonatal intensive care units. J Perinatol. Epub 2011 Apr 28. Cited in PubMed; PMID 21527902. Read the abstract.

Lorch SA, Srinivasan L, Escobar GJ. Epidemiology of apnea and bradycardia resolution in premature infants. Pediatrics. 2011 Aug;128(2):e366-73. Epub 2011 Jul 11. Cited in PubMed; PMID 21746726. Read the abstract.

Ma L, Liu C, Wang Y, Li S, Zhai S, Gu X, et al. Mortality of neonatal respiratory failure related to socioeconomic factors in Hebei province of China. Neonatology. 2011; 100(1):14-22. Epub 2010 Dec 10. Cited in PubMed; PMID 21150226. Read the abstract.

Oshodi A, Dysart K, Cook A, Rodriguez E, Zhu Y, Shaffer TH, et al. Airway injury resulting from repeated endotracheal intubation: Possible prevention strategies. Pediatr Crit Care Med. 2011 Jan;12(1):e34-9. Cited in PubMed; PMID 20375754. Read the abstract.

Pinney SE, Jaeckle Santos LJ, Han Y, Stoffers DA, Simmons RA. Exendin-4 increases histone acetylase activity and reverses epigenetic modifications that silence Pdx1 in the IUGR rat. Diabetologia, 54:2606-2614, 2011. Read the abstract.

Romer D, Betancourt LM, Bordsky NL, Giannetta JM, Yang W, Hurt H. Does adolescent risk taking imply weak executive function? A prospective study of relations between working memory performance, impulsivity, and risk taking in early adolescence. Dev Sci. 2011 Sep; 14(5):1119-33. doi: 10.1111/j.1467-7687.2011.01061.x. Epub 2011 Jun 18. Cited in PubMed; PMID 21884327. Read the abstract.

Ryan RM, Brion LP, Aucott SW, Juul SE, Parker TA, Savich RD, et al. Organization of Neonatal Training Program Directors Council responds to the ACGME 2010 Proposed Standards. J Perinatol. 2011 Apr;31(4):296-7. Cited in PubMed; PMID 21448184. Abstract not available.

Srinivasan L, Kilpatrick L, Abbasi S, Harris MC. Inflammation in neonatal bacterial meningitis: The role of novel biomarkers [abstract presentation]. 23rd Annual Meeting Eastern Society for Pediatric Research; 2011 Mar 25-27; Philadelphia, PA.

Srinivasan L, Kilpatrick L, Shah SS, Rankin SC, McGown KL, Abbasi S, et al. Cerebrospinal fluid (CSF) cytokines are predictors of bacterial meningitis in infants [abstract presentation]. 23rd Annual Meeting Eastern Society for Pediatric Research; 2011 Mar 25-27; Philadelphia, PA.

Srinivasan L, Shah SS, Padula MA, Abbasi S, McGowan KL, Harris MC. Reference ranges for cerebrospinal fluid (CSF) parameters in non-infected preterm and term infants in the NICU - a multicenter prospective study [abstract presentation]. 23rd Annual Meeting Eastern Society for Pediatric Research; 2011 Mar 25-27; Philadelphia, PA.

Stefan M, Simmons RA, Bertera S, Trucco M, Esni F, Drain P, Nicholls RD. Global deficits in development, function, and gene expression in the endocrine pancreas in a deletion mouse model of Prader-Willi syndrome. Am J Physiol Endocrinol Metab 300:E909-E992, 2011. Read the abstract. 

Tucker Edmonds B, Fager C, Srinivas S, Lorch S. Predictors of cesarean delivery for periviable neonates. Obstet Gynecol. 2011 Jul;118(1):49-56. Cited in PubMed; PMID 21691162. Read the abstract.

Tucker Edmonds B, Fager C, Srinivas S, Lorch S. Racial and ethnic differences in use of intubation for periviable neonates. Pediatrics. 2011 May;127(5):e1120-7. Epub 2011 Apr 18. Cited in PubMed; PMID 21502221. Read the abstract.

Wang X, Vatamaniuk M, Roneker C, Pepper MP, Hu L, Simmons R, Lei X. Knockouts of SOD1 and GPX1 exert different impacts on murine islet function and pancreatic integrity. Antioxid Redox Signal. 2011 February 1; 14(3): 391–401. Read the abstract.

Wright CJ, Kirpalani H. Targeting inflammation to prevent bronchopulmonary dysplasia: Can new insights be translated into therapies? Pediatrics. 2011 Jul;128(1):111-26. Epub 2011 Jun 6. Cited in PubMed; PMID 21646264. Read the abstract.

Yang G, Hinson MD, Bordner JE, Lin QZ, Fernando AP, La P, et al. Silencing hyperoxia-induced C/EBPα in neonatal mice improves lung architecture via enhanced proliferation of alveolar epithelial cells. Am J Physiol Lung Cell Mol Physiol. 2011 Aug;301(2):L187-96. Epub 2011 May 13. Cited in PubMed; PMID 21571903. Read the abstract.

Zisk JL, Genen LH, Kirkby S, Webb D, Greenspan J, Dysart K. Do premature female infants really do better than their male counterparts? Am J Perinatol. 2011 Mar;28(3):241-6. Epub 2010 Nov 2. Read the abstract.

The relationship of seizure activity and chronic epilepsy in early infancy and short-term neurodevelopmental outcome following fetal myelomeningocele closure. Danzer E, Finkel R, Gerdes M, Schwartz EM, Rintoul NN, Adzick NS, Johnson MP. Neuropediatrics. 2010 Jun;41(3):140-3. doi: 10.1055/s-0030-1263164. Epub 2010 Sep 21.PMID: 20859834

Neurodevelopmental outcome of infants with congenital diaphragmatic hernia prospectively enrolled in an interdisciplinary follow-up program. Danzer E, Gerdes M, Bernbaum J, D'Agostino J, Bebbington MW, Siegle J, Hoffman C, Rintoul NE, Flake AW, Adzick NS, Hedrick HL.J Pediatr Surg. 2010 Sep;45(9):1759-66. doi: 10.1016/j.jpedsurg.2010.03.011.PMID: 20850617

Prospective, interdisciplinary follow-up of children with prenatally diagnosed giant omphalocele: short-term neurodevelopmental outcome. Danzer E, Gerdes M, D'Agostino JA, Bernbaum J, Siegle J, Hoffman C, Rintoul NE, Liechty KW, Flake AW, Adzick NS, Hedrick HL.J Pediatr Surg. 2010 Apr;45(4):718-23. doi: 10.1016/j.jpedsurg.2009.09.004.PMID: 20385277

Ades AM, Dominguez TE, Nicolson SC, Gaynor JW, Spray TL, Wernovsky G, Tabbutt S. Morbidity and mortality after surgery for congenital cardiac disease in the infant born with low weight. Cardiol Young. 2010 Feb;20(1):8-17. Epub 2009 Dec 18. Read the abstract.

Binenbaum G, Bruno CJ, Forbes BJ, Snyder MA, Mollen TJ, Schmidt B, Peterside I. Periocular ulcerative dermatitis associated with gentamicin ointment prophylaxis in newborns. J Pediatr 2010;156:320-321. Cited in PubMed: PMID 20105641. Read the article.

Bloch JR, Webb DA, Mathews L, Fitzpatrick Dennis E, Bennet IM, Culhane JF. Beyond marital status: The quality of the mother-father relationship and its influence on reproductive health behaviors and outcomes among unmarried low income pregnant women. Matern Child Health J. 2010 Sep;14(5):726-34. Epub 2009 Aig 1. Cited in PubMed; PMID 19649696. Read the article.

Costales KC, Tanaka TY, Kilcommons MM, Takenaka WS, Sommer-Candelario SA, Ogino MT. Santa's got a brand new sled [platform presentation]. ECMO and the Advanced Therapies for Respiratory Failure; 2010 Feb; Keystone, CO.

Crowley M, Kirpalani H. A rational approach to red blood cell transfusion in the neonatal ICU. Current Opinion in Pediatrics. 2010 April;22(2):151-7. Read the abstract »

Danzer E, Gerdes M, Bernbaum J, D'Agostino J, Bebbington MW, Siegle J, et al. Neurodevelopmental outcome of infants with congenital diaphragmatic hernia prospectively enrolled in an interdisciplinary follow-up program. J Pediatr Surg. 2010 Sep;45(9):1759-66. Cited in PubMed; PMID 20850617. Read the abstract.

Danzer E, Gerdes M, D'Agostino JA, Bernbaum J, Siegle J, Hoffman C, et al. Prospective, interdisciplinary follow-up of children with prenatally diagnosed giant omphalocele: Short-term neurodevelopmental outcome. J Pediatr Surg. 2010 Apr;45(4):718-23. Cited in PubMed; PMID 20385277. Read the abstract.

Danzer E, Finkel R, Gerdes M, Schwartz EM, Rintoul NN, Adzick NS, et al. The relationship of seizure activity and chronic epilepsy in early infancy and short-term neurodevelopmental outcome following fetal myelomeningocele closure. Neuropediatrics. 2010 Jun;41(3):140-3. Epub 2010 Sep 21. Cited in PubMed; PMID 20859834. Read the abstract.

Davis PG, Schmidt B, Roberts RS, Doyle LW, Asztalos E, Haslam R, Sinha S, Tin W for the Caffeine for Apnea of Prematurity Trial Group: Caffeine for Apnea of Prematurity Trial: Benefits may vary in subgroups. J Pediatr. 2010 Mar;156(3):382-7. Epub 2009, Nov. 18. Read the abstract.»

Dotson JL, Hyams JS, Markowitz J, Leleiko NS, Mack DR, Evans JS, et al. Improving safety for babies during outpatient retinopathy of prematurity examination. J Pediatr Gastroenterol Nutr. Epub 2010 May 4. Read the abstract.

Foster CD, Varghese LS, Gonzales LW, Margulies SS, Guttentag SH. The Rho pathway mediates transition to an alveolar type I cell phenotype during static stretch of alveolar type II cells. Pediatr Res. 2010 Jun;67(6):585-90. Cited in PubMed; PMID 20220547. Read the article.

Frizzola M, Miller TL, Rodriguez ME, Zhu Y, Rojas J, Hesek A, et al. High-flow nasal cannula: Impact on oxygenation and ventilation in an acute lung injury model. Pediatr Pulmonol. 2011 Jan;46(1):67-74. Epub 2010 Nov 23. Cited in PubMed; PMID 21171186. Read the abstract.

Fuentes R, Wang Y, Hirsch J, Wang C, Rauova L, Worthen GS. Infusion of mature megakaryocytes into mice yields functional platelets. J Clin Invest. 2010 Nov 1;120(11):3917-22. doi: 10.1172/JC143326. Epub 2010 Oct 25. Cited in PubMed; PMID 20972336. Read the article.

Johnston LC, Gonzales LW, Lightfoot RT, Guttentag SH, Ischiropoulos H. Opposing regulation of human alveolar type II cell differentiation by nitric oxide and hyperoxia. Pediatr Res. 2010 May;67(5):521-5. Cited in PubMed; PMID 20098340. Read the article.

Kraft WK, Dysart K, Greenspan JS, Gibson E, Kaltenbach K, Ehrlich ME. Revised dose schema of sublingual buprenorphine in the treatment of the neonatal opioid abstinence syndrome. Addiction. Epub 2010 Oct 6. doi: 10.1111/j.1360-0443.2010.03170.x. Cited in PubMed; PMID 20925688. Read the abstract.

Kumar MA, Jain A, Dechant VE, Saito T, Rafael T, Aizawa H, et al. Anti-N-methyl-D-aspartate receptor encephalitis during pregnancy. Arch Neurol. 2010 Jul;67(7):884-7. Cited in PubMed; PMID 20625099. Read the article.

Lee GE, Lorch SA, Sheffler-Collins S, Kronman MP, Shah SS. National hospitalization trends for pediatric pneumonia and associated complications. Pediatrics. 2010 Aug;126(2):204-13. Epub 2010 Jul 19. Cited in PubMed; PMID 20643717. Read the article.

Lefkowitz DS, Baxt C, Evans JR. Prevalence and correlates of posttraumatic stress and postpartum depression in parents of infants in the neonatal intensive care unit (NICU). J Clin Psychol Med Settings. 2010 Sep;17(3):230-7. E pub 2010 Jul 15. Cited in PubMed; PMID 20632076. Read the abstract.

Lorch SA, Baiocchi M, Silber JH, Even-Shoshan O, Escobar GJ, Small DS. The role of outpatient facilities in explaining variations in risk-adjusted readmission rates between hospitals. Health Serv Res. 2010 Feb;45(1):24-41. Epub 2009 Sep 24. Cited in PubMed; PMID 19780853. Read abstract.

Lorch SA, Millman AM, Shah SS. Impact of congenital anomalies and treatment location on the outcomes of infants hospitalized with herpes simplex virus (HSV). J Hosp Med. 2010 Mar;5(3):154-9. Cited in PubMed; PMID 20235284. Read the abstract.

Lorch SA, Wade KC, Bakewell-Sachs S, Medoff-Cooper B, Silber JH, Escobar GJ. Antibiotic use in premature infants after discharge from the neonatal intensive care unit. Clin Pediatr (Phila). 2010 Apr;49(3):249-57. Epub 2009 May 15. Cited in PubMed; PMID 19448131. Read the abstract.

Mei J, Liu Y, Dai N, Favara M, Greene T, Jeyaseelan S, et al. CXCL5 regulates chemokine scavenging and pulmonary host defense to bacterial infection. Immunity. 2010 Jul 23;3(1):106-17. Cited in PubMed; PMID 20643340. Read the abstract.

Meyer A, Nadkarni V, Pollock A, Niles D, Braga M, Babbs C, Nishisaki A, Ades AM. Evaluation of the Neonatal Resuscitation Program's recommended chest compression depth using computerized tomography imaging. Resuscitation. Epub 2010, March 9. Read the abstract.

Oza V, Treat J, Cook N, Tetzlaff MT, Yan A. Subcutaneous fat necrosis as a complication of whole-body cooling for birth asphyxia. Arch Dermatol. 2010 Aug;146(8):882-5. Read the abstract.

Ray KN, Escobar GJ, Lorch SA. Premature infants born to adolescent mothers: healthcare utilization after initial discharge. Acad Pediatr. 2010 Sep-Oct;10(5):302-8. Cited in PubMed; PMID 20816654. Read the abstract.

Seligman NS, Almario CV, Hayes EJ, Dysart KC, Berghella V, Baxter JK. Relationship between maternal methadone dose at delivery and neonatal abstinence syndrome. J Pediatr. 2010 Sep;157(3):428-33, 433.e1. Epub 2010 May 15. Cited in PubMed; PMID 20472252. Read the abstract.

Sen S, Simmons RA. Maternal Antioxidant Supplementation Prevents Adiposity in the Offspring of Western diet-fed Dams. Diabetes. Epub 2010 Sep 7. Read the abstract.

Silber JH, Rosenbaum PR, Brachet TJ, Ross RN, Bressler LJ, Even-Shoshan O, Lorch SA, Volpp KG. The Hospital Compare mortality model and the volume-outcome relationship. Health Serv Res. 2010 Oct;45(5 Pt 1):1148-67. Cited in PubMed; PMID 20579125. Read the abstract.

Srinivas SK, Fager C, Lorch SA. Evaluating risk-adjusted cesarean delivery rate as a measure of obstetric quality. Obstet Gynecol. 2010 May;115(5):1007-13. Cited in PubMed; PMID 20410776. Read the abstract.

Srinivasan L, Kilpatrick L, Shah SS, Rankin SC, McGown KL, Abbasi S, et al. Impact of cerebrospinal fluid (CSF) cytokines on diagnosis of bacterial meningitis in infants [abstract presentation]. American Academy of Pediatrics National Conference; 2010 Oct 2-5; San Francisco, CA.

Srinivasan L, Pisapia J, Shah SS, Halpern C, Harris MC. Can the 16S ribosomal RNA (rRNA) gene PCR improve the diagnosis of bacterial meningitis in children? A systematic review. Eastern Society for Pediatric Research; 2010 Mar 26-28; Philadelphia, PA.

Stoller JZ, Huang L, Tan CC, Huang F, Zhou DD, Yang J, et al. Ash2l interacts with Tbx1 and is required during early embryogenesis. Exp Biol Med (Maywood). 2010 May;235(5):569-76. Cited in PubMed; PMID 20463296. Read the article.

Sullivan K, Samuel S, Smolenski J, Ciasullo N, Srinivasan L, Leone E, et al. Decreasing distraction during medication administration in a neonatal ICU [abstract presentation]. American Academy of Pediatrics National Conference; 2010 Oct 2-5; San Francisco, CA.

Sun B, Kirpalani H. Development of neonatal respiratory support and intensive care in emerging regions of China. Chin Med J (Engl). 2010 Oct;123(20):2757-8. Cited in PubMed; PMID 21034577. Read the article.

Tanaka LY, Aschwanden C, Burgess L, Ogino MT. Computer-based simulation for extracorporeal membrane oxygenation (ECMO) skills training [abstract]. International Medical Simulation in Healthcare; 2010 Jan; Phoenix, AZ.

Tabak BD, Tanaka LY, Mahnke CB, Elliott CL, Costales KG, Ogino MT. Echo for ECMO: guiding Avalon catheter placement for VV ECMO [platform presentation]. ECMO and the Advanced Therapies for Respiratory Failure; 2010 Feb; Keystone, CO.

Tabak BD, Tanaka LY, Mannke CB, Elliott CL, Costales KC, Ogino MT. Echocardiographic evaluation of the Avalon Elite Bi-caval Dual Lumen Catheter in neonatal and pediatric VV ECMO [abstract]. ECMO and the Advanced Therapies for Respiratory Failure; 2010 Feb; Keystone, CO.

Walsh MC, Hibbs AM, Martin CR, Cnaan A, Keller RL, Vittinghoff E, et al. Two-year neurodevelopmental outcomes of ventilated preterm infants treated with inhaled nitric oxide. J Pediatr. 2010 Apr;156(4):556-61.e.1. Epub 2010 Feb 6. Read the article.

Warren M, Grace CL, Mastuura-Eaves J, Ogino MT. An autopsy with vein of Galen malformation a possible hemodynamic mimic of severe persistent pulmonary hypertension of neonate [abstract]. Kaiser Permanente Research Symposia; 2010; Honolulu, HI.

Wright CJ, Agboke F, Chen F, La P, Yang G, Dennery PA. Nitric oxide inhibits hyperoxia-induced NF-kappaB activation in neonatal pulmonary microvascular endothelial cells. Pediatr Res. 2010 Dec;68(6):484-9. Epub 2010 Aug 27. Cited in PubMed; PMID 20805787. Read the abstract.

Wu WC, Jain V, Li C, Giannetta M, Hurt H, Wehrli FW, et al. In vivo venous blood T1 measurement using inversion recovery true-FISP in children and adults. Magn Reson Med. 2010 Oct;64(4):1140-7. Cited in PubMed; PMID 20564586. Read the article.

Zhuang T, Zhang M, Zhang H, Dennery PA, Lin QS. Disrupted postnatal lung development in heme oxygenase-1 deficient mice. Respir Res. 2010 Oct 10;11:142. Cited in PubMed; PMID 20932343. Read the article.

Zisk JL, Genen LH, Kirkby S, Webb D, Greenspan J, Dysart K. Do premature female infants really do better than their male counterparts? Am J Perinatol. Epub 2010 Nov 2. Cited in PubMed; PMID 21046537. Read the abstract.

Jensen EA, Allen BD, Kishi YK, O’Leary D. Conformational analysis of a covalently linked Watson-Crick base pair model. Bioorg Med Chem Lett. 2008 Nov 15;18(22):5884-7. doi: 10.1016/j.bmcl.2008.07.113. Epub 2008 Jul 31.

Reversal of hindbrain herniation after maternal-fetal surgery for myelomeningocele subsequently impacts on brain stem function. Danzer E, Finkel RS, Rintoul NE, Bebbington MW, Schwartz ES, Zarnow DM, Adzick NS, Johnson MP. Neuropediatrics. 2008 Dec;39(6):359-62. doi: 10.1055/s-0029-1202835. Epub 2009 Jun 30.PMID: 19569004

In utero meconium passage in fetuses and newborns with myelomeningocele. Danzer E, Ernst LM, Rintoul NE, Johnson MP, Adzick NS, Flake AW.J Neurosurg Pediatr. 2009 Feb;3(2):141-6. doi: 10.3171/2008.10.PEDS08199.PMID: 19278315

Intradural inclusion cysts following in utero closure of myelomeningocele: clinical implications and follow-up findings. Danzer E, Adzick NS, Rintoul NE, Zarnow DM, Schwartz ES, Melchionni J, Ernst LM, Flake AW, Sutton LN, Johnson MP. J Neurosurg Pediatr. 2008 Dec;2(6):406-13. doi: 10.3171/PED.2008.2.12.406.PMID: 19035686

Oelschlager BK, Lal DR, Jensen EA, Cahill M, and Pellegrini CA. Medium- and long-term outcome of laparoscopic redo fundoplication. Surg Endosc. 2006 Dec;20(12):1817-23.

Maternal-fetal surgery for myelomeningocele: neurodevelopmental outcomes at 2 years of age. Johnson MP, Gerdes M, Rintoul N, Pasquariello P, Melchionni J, Sutton LN, Adzick NS.Am J Obstet Gynecol. 2006 Apr;194(4):1145-50; discussion 1150-2. doi: 10.1016/j.ajog.2006.01.072.PMID: 16580316

Fetal myelomeningocele repair: short-term clinical outcomes. Johnson MP, Sutton LN, Rintoul N, Crombleholme TM, Flake AW, Howell LJ, Hedrick HL, Wilson RD, Adzick NS.Am J Obstet Gynecol. 2003 Aug;189(2):482-7. doi: 10.1067/s0002-9378(03)00295-3.PMID: 14520222

Correction of hindbrain herniation and anatomy of the vermis after in utero repair of myelomeningocele in sheep. Bouchard S, Davey MG, Rintoul NE, Walsh DS, Rorke LB, Adzick NS.J Pediatr Surg. 2003 Mar;38(3):451-8; discussion 451-8. doi: 10.1053/jpsu.2003.50078.PMID: 12632366 RESULTS: After MMC creation, significant cerebellar tonsillar herniation was observed in 85% of fetuses that underwent creation of a myelotomy; none of the lambs without a myelotomy (n = 6) had hindbrain herniation. At autopsy, cerebellar tonsillar herniation was present a …

Prenatal diagnosis and treatment of intersex states. Rintoul NE, Crombleholme TM.Adv Exp Med Biol. 2002;511:225-37; discussion 237-8. doi: 10.1007/978-1-4615-0621-8_13.PMID: 12575764 Review. No abstract available.

A new look at myelomeningoceles: functional level, vertebral level, shunting, and the implications for fetal intervention. Rintoul NE, Sutton LN, Hubbard AM, Cohen B, Melchionni J, Pasquariello PS, Adzick NS. Pediatrics. 2002 Mar;109(3):409-13. doi: 10.1542/peds.109.3.409.PMID: 11875133

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Neonatal Nurse and Nurse Practitioner Engagement in Antibiotic Stewardship: A Call to Action

Advances in Neonatal Care. 24(3):209-211, June 2024.

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Implementation of a Nurse-Driven Eat-Sleep-Console (ESC) Treatment Pathway at a Community Hospital for Treatment of Neonatal Opioid Withdrawal Syndrome in an Effort to Improve Short-term Outcomes

Advances in Neonatal Care. 24(3):212-218, June 2024.

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Reducing Procedural Pain and Avoiding Peripheral Intravenous Catheters by Implementing a Feeding Protocol for Late Preterm Infants: A Quality Improvement Project

Advances in Neonatal Care. 24(3):219-226, June 2024.

Implementation of an Extubation Readiness Guideline for Preterm Infants

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Hepatitis B Birth Dose Vaccination Improvement Initiative: The 24-Hour Baby Bundle

Advances in Neonatal Care. 24(3):237-242, June 2024.

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Pilot Testing Transcreated Spanish-Language Study Materials for Symptom Research With Infants and Parents in the Neonatal Intensive Care Unit

Advances in Neonatal Care. 24(3):243-252, June 2024.

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A Narrative Review of NICU Implementation of Evidence-Based Early Relational Health Interventions

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SARS-CoV-2 Infection Among Newborn Infants: A Scoping Review

Advances in Neonatal Care. 24(3):268-276, June 2024.

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Targeted Neonatal Echocardiography Performed by Nurse Practitioners in the NICU: Attitudes and Perceptions of the Healthcare Team

Advances in Neonatal Care. 24(3):277-284, June 2024.

Skin-to-Skin Contact and Diaphragm Electrical Activity in Preterm Infants During Noninvasive Pressure Control

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Effects of White Noise on Pain Scores and Salivary Cortisol Levels in Surgical Neonates: A Randomized Controlled Trial

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Performance Evaluation of a Supervised Machine Learning Pain Classification Model Developed by Neonatal Nurses

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The Effect of Abdominal Massage on Bilirubin Levels in Term Infants Receiving Phototherapy: A Randomized Controlled Trial

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Qualitative Insights Into Enhancing Neonatal Resuscitation in Post-Pandemic Vietnam: A Stakeholder Perspective on the Helping Babies Breathe Program

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2023 Faculty Publications

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Panelli, D. M., Chan, C. S., Shaw, J. G., Shankar, M., Kimerling, R., Frayne, S. M., Herrero, T. C., Lyell, D. J., & Phibbs, C. S. (2023). An exploratory analysis of factors associated with spontaneous preterm birth among pregnant veterans with post-traumatic stress disorder. Womens Health Issues , 33 (2), 191-198. https://doi.org/10.1016/j.whi.2022.09.005

Giuliano, J., Jr., Krishna, A., Napolitano, N., Panisello, J., Shenoi, A., Sanders, R. C., Jr., . . . Yamada, N. K. , . . . National Emergency Airway Registry for Children Pediatric Acute Lung Injury & Sepsis Investigators Network. (2023). Implementation of Video Laryngoscope-Assisted Coaching Reduces Adverse Tracheal Intubation-Associated Events in the PICU. Crit Care Med , 51 (7), 936-947. https://doi.org/10.1097/CCM.0000000000005847

Sindher, S. B., Chin, A. R., Aghaeepour, N., Prince, L. , Maecker, H., Shaw, G. M. , Stevenson, D. K. , . . . & Chinthrajah, R. S. (2023). Advances and potential of omics studies for understanding the development of food allergy. Front Allergy , 4 , 1149008. https://doi.org/10.3389/falgy.2023.1149008

Danielsen, B. H., Carmichael, S. L. , Gould, J. B. , & Lee, H. C. (2023). Linked birth cohort files for perinatal health research: California as a model for methodology and implementation. Ann Epidemiol , 79 , 10-18. https://doi.org/10.1016/j.annepidem.2022.12.014

Tawfik, D. S., Adair, K. C., Palassof, S., Sexton, J. B., Levoy, E., Frankel, A., . . . & Profit, J. (2023). Leadership Behavior Associations with Domains of Safety Culture, Engagement, and Health Care Worker Well-Being. Jt Comm J Qual Patient Saf , 49 (3), 156-165. https://doi.org/10.1016/j.jcjq.2022.12.006

Adair, K. C., Levoy, E., Tawfik, D. S., Palassof, S., Profit, J. , Frankel, A., . . . & Sexton, J. B. (2023). Assessing Leadership Behavior in Health Care: Introducing the Local Leadership Scale of the SCORE Survey. Jt Comm J Qual Patient Saf , 49 (3), 166-173. https://doi.org/10.1016/j.jcjq.2022.12.007

Kumar, K., Marchman, V. A., Morales, M. C., Scala, M. , & Travis, K. E. (2023). Investigating Relations between the NICU Speech Environment and Weight Gain in Infants Born Very Preterm. Am J Perinatol . https://doi.org/10.1055/a-2023-8813

McCoy, A. M., Lakhdari, O., Shome, S., Caoili, K., Hernandez, G. E., Aghaeepour, N., . . . & Prince, L. S. (2023). Sp3 is essential for normal lung morphogenesis and cell cycle progression during mouse embryonic development. Development , 150 (5). https://doi.org/10.1242/dev.200839

Hintz, S. R. , deRegnier, R. A., & Vohr, B. R. (2023). Outcomes of Preterm Infants: Shifting Focus, Extending the View. Clin Perinatol , 50 (1), 1-16. https://doi.org/10.1016/j.clp.2022.10.001

Walravens, C., Gupta, A. , Cohen, R. S. , Kim, J. L., & Frymoyer, A. (2023). Fewer glucose checks and decreased supplementation using dextrose gel for asymptomatic neonatal hypoglycemia. J Perinatol , 43 (4), 532-537. https://doi.org/10.1038/s41372-023-01638-z

Liang, R., Panelli, D. M., Stevenson, D. K. , Rehkopf, D. H., & Shaw, G. M. (2023). Associations between pregnancy glucose measurements and risk of preterm birth: a retrospective cohort study of commercially insured women in the United States from 2003 to 2021. Ann Epidemiol . https://doi.org/10.1016/j.annepidem.2023.03.002

Mujahid, M. S., Wall-Wieler, E., Hailu, M. E. M., Berkowitz, R. L., Gao, M. X., Morris, M. C. M., . . . & Carmichael, S. L. (2023). Neighborhood Deprivation and Severe Maternal Morbidity in the State of California: An Examination of Effect Modification by Race/Ethnicity. Am J Obstet Gynecol MFM , 100916. https://doi.org/10.1016/j.ajogmf.2023.100916

Baliga, K., Halamek, L. P. , Warburton, S., Mathias, D., Yamada, N. K. , Fuerch, J. H. , & Coggins, A. (2023). The Debriefing Assessment in Real Time (DART) tool for simulation-based medical education. Adv Simul (Lond) , 8 (1), 9. https://doi.org/10.1186/s41077-023-00248-1

Stevenson, D. K. , Maric, I., & Wong, R. J. (2023). Breath: The Exhaust of Metabolism. J Pediatr , 113386. https://doi.org/10.1016/j.jpeds.2023.03.002

Kononowech, J., Landis-Lewis, Z., Carpenter, J., Ersek, M., Hogikyan, R., Levy, C., Phibbs, C. , . . . & Sales, A. E. (2023). Correction: Visual process maps to support implementation efforts: a case example. Implement Sci Commun , 4 (1), 29. https://doi.org/10.1186/s43058-023-00414-6

Sok, P., Sabo, A., Almli, L. M., Jenkins, M. M., Nembhard, W. N., Agopian, A. J., . . . Carmichael, S. L. , . . . Shaw, G. M. , Werler, M. M., Harpavat, S., Lupo, P. J., & University of Washington Center for Mendelian Genomics, NICS Comparative Sequencing Program, the National Birth Defects Prevention Study (2023). Exome-wide assessment of isolated biliary atresia: A report from the National Birth Defects Prevention Study using child-parent trios and a case-control design to identify novel rare variants. Am J Med Genet A . https://doi.org/10.1002/ajmg.a.63185

Holzapfel, L., Arnold, C. , Tyson, J., Shapiro, S., Reynolds, E., Pedroza, C., . . . & Lopez, M. (2023). Effect of Reduced Versus Usual Lipid Emulsion Dosing on Bilirubin Neurotoxicity and Neurodevelopmental Impairment in Extremely Preterm Infants: Study Protocol for a Randomized Controlled Trial. Res Sq . https://doi.org/10.21203/rs.3.rs-2566352/v1

Golob, J. L., Oskotsky, T. T., Tang, A. S., Roldan, A., Chung, V., Ha, C. . . . Stevenson, D. K. , . . . & Sirota, M. (2023). Microbiome Preterm Birth DREAM Challenge: Crowdsourcing Machine Learning Approaches to Advance Preterm Birth Research. medRxiv . https://doi.org/10.1101/2023.03.07.23286920

Hawken, S., Ward, V., Bota, A. B., Lamoureux, M., Ducharme, R., Wilson, L. A., . . . Stevenson, D. K. , . . . Darmstadt, G. L. , & Wilson, K. (2022). Real world external validation of metabolic gestational age assessment in Kenya. PLOS Glob Public Health , 2 (11), e0000652. https://doi.org/10.1371/journal.pgph.0000652

Chock, V. Y. , Rao, A. , & Van Meurs, K. P. (2023). Optimal neuromonitoring techniques in neonates with hypoxic ischemic encephalopathy. Front Pediatr , 11 , 1138062. https://doi.org/10.3389/fped.2023.1138062

Neo, D. T., Desrosiers, T. A., Martin, C. L., Carmichael, S. L. , Gucsavas-Calikoglu, M., Conway, K. M., . . . Shaw, G. M. , . . . & National Birth Defects Prevention Study. (2023). Neighborhood-level socioeconomic position during early pregnancy and risk of gastroschisis. Epidemiology . https://doi.org/10.1097/EDE.0000000000001621

Stevenson, D. K. , Vreman, H. J., & Wong, R. J. (2023). Heme, Heme Oxygenase-1, Statins, and SARS-CoV-2. Antioxidants (Basel) , 12 (3). https://doi.org/10.3390/antiox12030614

Roger, J., Xie, F., Costello, J., Tang, A., Liu, J., Oskotsky, T., . . . Shaw, G. , Stevenson, D. , . . . & Sirota, M. (2023). Leveraging electronic health records to identify risk factors for recurrent pregnancy loss across two medical centers: a case-control study. Res Sq . https://doi.org/10.21203/rs.3.rs-2631220/v1

Hsu, J., Fatuzzo, N., Weng, N., Michno, W., Dong, W., Kienle, M., . . . Pasca, A. , . . . & Khosla, C. (2023). Carnitine octanoyltransferase is important for the assimilation of exogenous acetyl-L-carnitine into acetyl-CoA in mammalian cells. J Biol Chem , 299 (2), 102848. https://doi.org/10.1016/j.jbc.2022.102848

Munive, A., Donville, J., & Darmstadt, G. L. (2023). Public leadership for gender equality: A framework and capacity development approach for gender transformative policy change. EClinicalMedicine , 56 , 101798. https://doi.org/10.1016/j.eclinm.2022.101798

Canvasser, J., Patel, R. M., Pryor, E., Green, L., Hintz, S. R. , Fagan, M., & Harrison, J. D. (2023). Long-term outcomes and life-impacts of necrotizing enterocolitis: A survey of survivors and parents. Semin Perinatol , 47 (1), 151696. https://doi.org/10.1016/j.semperi.2022.151696

Sperling, M. M., Leonard, S. A., Blumenfeld, Y. J., Carmichael, S. L. , & Chueh, J. (2023). Prepregnancy body mass index and gestational diabetes mellitus across Asian and Pacific Islander subgroups in California. AJOG Glob Rep , 3 (1), 100148. https://doi.org/10.1016/j.xagr.2022.100148

Noh, C. Y. , Chock, V. Y. , Bhombal, S., Danzer, E., Patel, N., Dahlen, A., . . . Van Meurs, K. P. , & Congenital Diaphragmatic Hernia Study Group. (2023). Early nitric oxide is not associated with improved outcomes in congenital diaphragmatic hernia. Pediatr Res . https://doi.org/10.1038/s41390-023-02491-8

Yu, B., Zhang, C. A., Chen, T., Mulloy, E., Shaw, G. M. , & Eisenberg, M. L. (2023). Congenital male genital malformations and paternal health: An analysis of the US claims data. Andrology . https://doi.org/10.1111/andr.13404

Sewell, E. K., Shankaran, S., McDonald, S. A., Hamrick, S., Wusthoff, C. J., Adams-Chapman, I., . . .   Davis, A. S. , Van Meurs, K. , . . . National Institute of Child Health & Human Development Neonatal Research Network. (2023). Antiseizure medication at discharge in infants with hypoxic-ischaemic encephalopathy: an observational study. Arch Dis Child Fetal Neonatal Ed . https://doi.org/10.1136/archdischild-2022-324612

Lee, S. M., Sie, L., Liu, J., Profit, J. , Main, E., & Lee, H. C. (2023). Racial and ethnic disparities in postnatal growth among very low birth weight infants in California. J Perinatol , 43 (3), 371-377. https://doi.org/10.1038/s41372-023-01612-9

Tawfik, D. S., Rovnaghi, C., Profit, J. , Cornell, T. T., & Anand, K. J. S. (2023). Prevalence of burnout and its relation to the neuroendocrine system among pediatric residents during the early Covid-19 pandemic: A pilot feasibility study. Compr Psychoneuroendocrinol , 14 , 100174. https://doi.org/10.1016/j.cpnec.2023.100174

Rumpel, J. A., Spray, B. J., Frymoyer, A. , Rogers, S., Cho, S. H., Ranabothu, S., . . . & Chock, V. Y. (2023). Renal oximetry for early acute kidney injury detection in neonates with hypoxic ischemic encephalopathy receiving therapeutic hypothermia. Pediatr Nephrol . https://doi.org/10.1007/s00467-023-05892-3

De Francesco, D., Reiss, J. D. , Roger, J., Tang, A. S., Chang, A. L., Becker, M., . . . Prince, L. S. , . . . Benitz, W. E. , Fuerch, J. H. , Shaw, G. M. , . . . Stevenson, D. K. , . . . & Aghaeepour, N. (2023). Data-driven longitudinal characterization of neonatal health and morbidity. Sci Transl Med , 15 (683), eadc9854. https://doi.org/10.1126/scitranslmed.adc9854

Coggins, A., Hong, S. S., Baliga, K., & Halamek, L. P. (2023). Correction: Immediate faculty feedback using debriefing timing data and conversational diagrams. Adv Simul (Lond) , 8 (1), 6. https://doi.org/10.1186/s41077-023-00247-2

Stevenson, D. K. , Wong, R. J., & Nayak, N. R. (2023). Molecular Mechanisms of Pregnancy-Related Vascular Remodeling and Pregnancy Complications. Int J Mol Sci , 24 (4). https://doi.org/10.3390/ijms24043712

Carrasco, M., Bonifacio, S. L. , deVeber, G., & Chau, V. (2023). Early Discontinuation of Phenobarbital After Acute Symptomatic Neonatal Seizures in the Term Newborn. Neurol Clin Pract , 13 (2), e200125. https://doi.org/10.1212/CPJ.0000000000200125

Hedou, J., Maric, I., Bellan, G., Einhaus, J., Gaudilliere, D., Ladant, F. X., . . . Stevenson, D. , . . . & Gaudilliere, B. (2023). Stabl: sparse and reliable biomarker discovery in predictive modeling of high-dimensional omic data. Res Sq . https://doi.org/10.21203/rs.3.rs-2609859/v1

Aiden, A. P., Khan, A., Schwenk, H., & Fuerch, J. H. (2023). Respiratory Failure in an 11-day-old Neonate. Neoreviews , 24 (1), 36-38. https://doi.org/10.1542/neo.24-1-e36

Payton, K. S. E., & Gould, J. B. (2022). Vignette Research Methodology: An Essential Tool for Quality Improvement Collaboratives. Healthcare (Basel) , 11 (1). https://doi.org/10.3390/healthcare11010007

DeZure, C. (2023). COVID-19 Vaccines in Children. Pediatr Ann , 52 (1), e4-e7. https://doi.org/10.3928/19382359-20221114-02

Oner, A., Dittrich, H., Arslan, F., Hintz, S. , Ortak, J., Brandewiede, B., . . . & CardioCare, MV Study Group. (2023). Comparison of telemonitoring combined with intensive patient support with standard care in patients with chronic cardiovascular disease - a randomized clinical trial. Eur J Med Res , 28 (1), 22. https://doi.org/10.1186/s40001-023-00991-1

Kancherla, V., Ma, C., Purkey, N. J., Hintz, S. R. , Lee, H. C. , Grant, G., & Carmichael, S. L. (2023). Factors Associated with Transfer Distance from Birth Hospital to Repair Hospital for First Surgical Repair among Infants with Myelomeningocele in California. Am J Perinatol . https://doi.org/10.1055/s-0042-1760431

Chen, Y., Wu, Y., Dill, S. E., Guo, Y., Westgard, C. M., . . . Darmstadt, G. L. , . . . & Sylvia, S. (2023). Effect of the mHealth-supported Healthy Future programme delivered by community health workers on maternal and child health in rural China: study protocol for a cluster randomised controlled trial. BMJ Open , 13 (1), e065403. https://doi.org/10.1136/bmjopen-2022-065403

Boddy, M. G., Davis, A. S. , & Perlman, N. (2023). The pregnancy at risk for delivery at the threshold of viability. Curr Opin Obstet Gynecol , 35 (2), 101-105. https://doi.org/10.1097/GCO.0000000000000850

April , May , June

Number of Publications

quarter : 46

year-to-date : 91

Quinn, J., Quinn, M., Lieu, B., Bohnert, J., Halamek, L. P. , Profit, J. , Fuerch, J. H., Chitkara, R. , Yamada, N. K. , Gould, J. , & Lee, H. C. (2023). Neonatal Healthcare Professionals' Experiences When Implementing a Simulation and Debriefing Program in Neonatal Intensive Care Settings: A Qualitative Analysis. Adv Neonatal Care , 23 (5), 425-434. https://doi.org/10.1097/ANC.0000000000001085

Variane, G. F. T., Dahlen, A., Noh, C. Y., Zeng, J., Yan, E. S., Kaneko, J. S., Gouveia, M. S., Van Meurs, K. P. , & Chock, V. Y. (2023). Cerebral oxygen saturation in neonates: a bedside comparison between neonatal and adult NIRS sensors. Pediatr Res . https://doi.org/10.1038/s41390-023-02705-z

Yamada, N. K. , & Halamek, L. P. (2023). The Evolution of Neonatal Patient Safety. Clin Perinatol , 50 (2), 421-434. https://doi.org/10.1016/j.clp.2023.01.005

Leonard, S. A., Girsen, A. I., Trepman, P., Carmichael, S. L. , Darmawan, K., Butwick, A. J., & Gibbs, R. S. (2023). Early Postpartum Hospital Encounters among Patients with Genitourinary and Wound Infections during Hospitalization for Birth. Am J Perinatol . https://doi.org/10.1055/a-2097-1584

Lanzieri, T. M., Lu, T., Bennett, M. V., Hintz, S. R. , Sugerman, D. E., Dollard, S. C., . . . & Lee, H. C. (2023). Early childhood outcomes of NICU graduates with cytomegalovirus infection in California. Birth Defects Res , 115 (11), 1093-1100. https://doi.org/10.1002/bdr2.2203

Boghossian, N. S., Greenberg, L. T., Saade, G. R., Rogowski, J., Phibbs, C. S. , Passarella, M., . . . & Lorch, S. A. (2023). Association of Sickle Cell Disease With Racial Disparities and Severe Maternal Morbidities in Black Individuals. JAMA Pediatr . https://doi.org/10.1001/jamapediatrics.2023.1580

Padua, K., Robinson, R., Ness, A., Judy, A., Lee, G. M., & Gould, J. (2023). Moms in the NICU: developing a pilot to engage and empower women who have delivered a prematurely born infant. BMC Pregnancy Childbirth , 23 (1), 432. https://doi.org/10.1186/s12884-023-05738-8

Sabir, H., Maes, E., Zweyer, M., Schleehuber, Y., Imam, F. B., Silverman, J., . . . Pasca, A. M. , . . . & Bernis, M. E. (2023). Comparing the efficacy in reducing brain injury of different neuroprotective agents following neonatal hypoxia-ischemia in newborn rats: a multi-drug randomized controlled screening trial. Sci Rep , 13 (1), 9467. https://doi.org/10.1038/s41598-023-36653-9

Blumenfeld, Y. J., Hintz, S. R. , Aziz, N., Barth, R. A., Spano, J. M., El-Sayed, Y. Y., & Milla, C. (2023). Treatment of Fetal Cystic Fibrosis With Cystic Fibrosis Transmembrane Conductance Regulator Modulation Therapy. Ann Intern Med . https://doi.org/10.7326/L23-0112

Carmichael, S. L. , Yang, W., Ma, C., Desrosiers, T. A., Weber, K., Collins, R. T., . . . Shaw, G. M. , & National Birth Defects Prevention Study. (2023). Oxidative balance scores and neural crest cell-related congenital anomalies. Birth Defects Res , 115 (12), 1151-1162. https://doi.org/10.1002/bdr2.2211

Punjabi, S. , Blankenburg, R., Blecharczyk, E. , & Team, C. S. (2023). Development of a Multi-site Curriculum for Inequities in Newborn Care (CINC) Informed by Pediatric Resident and Community Engagement. Acad Pediatr . https://doi.org/10.1016/j.acap.2023.06.019

Kozhimannil, K. B., Leonard, S. A., Handley, S. C., Passarella, M., Main, E. K., Lorch, S. A., & Phibbs, C. S. (2023). Obstetric Volume and Severe Maternal Morbidity Among Low-Risk and Higher-Risk Patients Giving Birth at Rural and Urban US Hospitals. JAMA Health Forum , 4 (6), e232110. https://doi.org/10.1001/jamahealthforum.2023.2110

Blumenfeld, Y. J., Maric, I., Stevenson, D. K. , Gibbs, R. S., & Shaw, G. M. (2023). Persistent Bacterial Vaginosis and Risk for Spontaneous Preterm Birth. Am J Perinatol . https://doi.org/10.1055/s-0043-1770703

Weber, A. M., & Darmstadt, G. L. (2023). Nurturing the nurturing care environment. Lancet Child Adolesc Health , 7 (5), 298-299. https://doi.org/10.1016/S2352-4642(23)00054-8

Tsur, A., Leonard, S. A., Kan, P., Datoc, I. A., Girsen, A. I., Shaw, G. M. , Stevenson, D. K. , . . . & Blumenfeld, Y. J. (2023). Vaginal Progesterone Is Associated with Intrahepatic Cholestasis of Pregnancy. Am J Perinatol . https://doi.org/10.1055/a-2081-2573

Carmichael, S. L. , & Snowden, J. (2023). Racial and Ethnic Disparities in Primary Cesarean Birth and Adverse Outcomes Among Low-Risk Nulliparous People. Obstet Gynecol , 141 (5), 1024. https://doi.org/10.1097/AOG.0000000000005158

Gu, H., Perl, J., Rhine, W. , Yamada, N. K. , Sherman, J., McMillin, A., Halamek, L. P. , . . . & Fuerch, J. H. (2023). A Novel Method for Administering Epinephrine during Neonatal Resuscitation. Am J Perinatol . https://doi.org/10.1055/a-2082-4729

Vidavalur, R., & Bhutani, V. K. (2023). Georacial Epidemiological Estimates of Glucose-6-Phosphate Dehydrogenase Deficiency among Newborns in the United States. Am J Perinatol . https://doi.org/10.1055/a-2082-4859

Boghossian, N. S., Geraci, M., Phibbs, C. S. , Lorch, S. A., Edwards, E. M., & Horbar, J. D. (2023). Trends in Resources for Neonatal Intensive Care at Delivery Hospitals for Infants Born Younger Than 30 Weeks' Gestation, 2009-2020. JAMA Netw Open , 6 (5), e2312107. https://doi.org/10.1001/jamanetworkopen.2023.12107

Sperry, M. M., Oskotsky, T. T., Maric, I., Kaushal, S., Takeda, T., Horvath, V., . . . Stevenson, D. K. , . . . & Novak, R. (2023). Target-agnostic drug prediction integrated with medical record analysis uncovers differential associations of statins with increased survival in COVID-19 patients. PLoS Comput Biol , 19 (5), e1011050. https://doi.org/10.1371/journal.pcbi.1011050

Wenani, D., Burgoine, K., Williams, S., Musaba, M., Gebremichael, T., Clarke, A., . . . Darmstadt, G. L. , . . . & Mukunya, D. (2023). Perceptions, beliefs, and current practices regarding neonatal skin care and emollient use in eastern Uganda: a qualitative study. BMC Pediatr , 23 (1), 223. https://doi.org/10.1186/s12887-023-04040-y

Okwundu, C. I., Olowoyeye, A., Uthman, O. A., Smith, J., Wiysonge, C. S., Bhutani, V. K. , Fiander, M., & Gautham, K. S. (2023). Transcutaneous bilirubinometry versus total serum bilirubin measurement for newborns. Cochrane Database Syst Rev , 5 (5), CD012660. https://doi.org/10.1002/14651858.CD012660.pub2

DeZure, C. (2023). Gender-Affirming Care in Children. Pediatr Ann , 52 (5), e160-e163. https://doi.org/10.3928/19382359-20230307-03

Dershowitz, L. B., Li, L., Pasca, A. M. , & Kaltschmidt, J. A. (2023). Anatomical and functional maturation of the mid-gestation human enteric nervous system. Nat Commun , 14 (1), 2680. https://doi.org/10.1038/s41467-023-38293-z

Rysavy, M. A., Eggleston, B., Dahabreh, I., Tyson, J. E., Patel, R. M., Watterberg, K. L., . . . Stevenson, D. K. , . . . Eunice Kennedy Shriver National Institute of Child Health & Human Development Neonatal Research Network. (2023). Generalizability of the Necrotizing Enterocolitis Surgery Trial (NEST) to the Target Population of Eligible Infants. J Pediatr , 113453. https://doi.org/10.1016/j.jpeds.2023.113453

Panelli, D. M., Nelson, D. A., Wagner, S., Shaw, J. G., Phibbs, C. S. , & Kurina, L. M. (2023). Physical Fitness in Relationship to Depression and Post-Traumatic Stress Disorder During Pregnancy Among U.S. Army Soldiers. J Womens Health (Larchmt) . https://doi.org/10.1089/jwh.2022.0538

Moufarrej, M. N., Bianchi, D. W., Shaw, G. M. , Stevenson, D. K. , & Quake, S. R. (2023). Noninvasive Prenatal Testing Using Circulating DNA and RNA: Advances, Challenges, and Possibilities. Annu Rev Biomed Data Sci . https://doi.org/10.1146/annurev-biodatasci-020722-094144

Darmstadt, G. L. , Kirkwood, B., Gupta, S., Strategic, WHO Technical Advisory Group of Experts for Maternal, Newborn, Child, and Adolescent Health, & Nutrition KMC Working Group. (2023). WHO Global Position Paper and Implementation Strategy on kangaroo mother care call for fundamental reorganisation of maternal-infant care. Lancet , 401 (10390), 1751-1753. https://doi.org/10.1016/S0140-6736(23)01000-0

Shaw, J. G., Goldthwaite, L. M., Maric, I., Shaw, K. A., Stevenson, D. K. , & Shaw, G. M. (2023). Postpartum long-acting reversible contraception among privately insured: National analysis 2007-2016, by term and preterm birth. Contraception , 110065. https://doi.org/10.1016/j.contraception.2023.110065

Scala, M. , Marchman, V. A., Dowtin, L. L., Givrad, S., Nguyen, T., Thomson, . . . & Hall, S. (2022). Evaluation of a course for neonatal fellows on providing psychosocial support to NICU families. PEC Innov , 1 , 100053. https://doi.org/10.1016/j.pecinn.2022.100053

Espinosa, C. A., Khan, W., Khanam, R., Das, S., Khalid, J., Pervin, J., . . . Wise, P. H. , . . . Darmstadt, G. L. , . . . Shaw, G. M. , Stevenson, D. K. , & Aghaeepour, N. (2023). Multiomic signals associated with maternal epidemiological factors contributing to preterm birth in low- and middle-income countries. Sci Adv , 9 (21), eade7692. https://doi.org/10.1126/sciadv.ade7692

Gentle, S. J., Rysavy, M. A., Li, L., Laughon, M. M., Patel, R. M., Jensen, E. A., Hintz, S. , . . . National Institute of Child Health & Human Development Neonatal Research Network. (2023). Heterogeneity of Treatment Effects of Hydrocortisone by Risk of Bronchopulmonary Dysplasia or Death Among Extremely Preterm Infants in the National Institute of Child Health and Human Development Neonatal Research Network Trial: A Secondary Analysis of a Randomized Clinical Trial. JAMA Netw Open , 6 (5), e2315315. https://doi.org/10.1001/jamanetworkopen.2023.15315

Feister, J., Kan, P., Bonifacio, S. L. , Profit, J. , & Lee, H. C. (2023). Association of Primary Language with Very Low Birth Weight Outcomes in Hispanic Infants in California. J Pediatr , 261 , 113527. https://doi.org/10.1016/j.jpeds.2023.113527

Chock, V. Y. , & Van Meurs, K. P. (2023). Editorial: Advances in the use of neuromonitoring in newborns. Front Pediatr , 11 , 1215991. https://doi.org/10.3389/fped.2023.1215991

Zhang, Y., Sylvester, K. G., Jin, B., Wong, R. J., Schilling, J., Chou, C. J., . . . Darmstadt, G. L. , Shaw, G. M. , Stevenson, D. K. , . . . & Ling, X. B. (2023). Development of a Urine Metabolomics Biomarker-Based Prediction Model for Preeclampsia during Early Pregnancy. Metabolites , 13 (6). https://doi.org/10.3390/metabo13060715

Darmstadt, G. L. , Mader, S., & Edmond, K. (2023). The needs of children born preterm are too often overlooked - Authors' reply. Lancet , 401 (10383), 1156-1157. https://doi.org/10.1016/S0140-6736(23)00243-X

Noh, C. Y., Chock, V. Y. , Bhombal, S., Danzer, E., Patel, N., Dahlen, A., . . . Van Meurs, K. P. , & Congenital Diaphragmatic Hernia Study Group. (2023). Correction To: Early nitric oxide is not associated with improved outcomes in congenital diaphragmatic hernia. Pediatr Res . https://doi.org/10.1038/s41390-023-02581-7

Dubner, S. E., Morales, M. C., Marchman, V. A., Shaw, R. J., Travis, K. E., & Scala, M. (2023). Maternal mental health and engagement in developmental care activities with preterm infants in the NICU. J Perinatol , 43 (7), 871-876. https://doi.org/10.1038/s41372-023-01661-0

Rao, A. , Eskandar-Afshari, F., Weiner, Y., Billman, E., McMillin, A., Sella, N., . . . Rhine, W. , & Quan, X. (2023). Clinical Study of Continuous Non-Invasive Blood Pressure Monitoring in Neonates. Sensors (Basel) , 23 (7). https://doi.org/10.3390/s23073690

Lazarus, M. F., Marchman, V. A., Brignoni-Perez, E., Dubner, S., Feldman, H. M., Scala, M. , & Travis, K. E. (2023). Inpatient Kangaroo Care Predicts Early Cognitive Development at 6 and 12 Months in Infants Born Very Preterm. medRxiv . https://doi.org/10.1101/2023.04.06.23288260

Robinson, K., Mosley, T. J., Rivera-Gonzalez, K. S., Jabbarpour, C. R., Curtis, S. W., Adeyemo, W. L.,  . . . Shaw, G. M. , . . . & Leslie, E. J. (2023). Trio-based GWAS identifies novel associations and subtype-specific risk factors for cleft palate. medRxiv . https://doi.org/10.1101/2023.03.01.23286642

Andersen, J., Thom, N., Shadrach, J. L., Chen, X., Onesto, M. M., Amin, N. D., . . . Pasca, A. M. , . . . & Pasca, S. P. (2023). Single-cell transcriptomic landscape of the developing human spinal cord. Nat Neurosci , 26 (5), 902-914. https://doi.org/10.1038/s41593-023-01311-w

Brumbaugh, J. E., Vohr, B. R., Bell, E. F., Bann, C. M., Travers, C. P., McGowan, E. C., . . . Hintz, S. R. , & Eunice Kennedy Shriver National Institute of Child Health and Development Neonatal Research Network. (2023). Early-Life Outcomes in Relation to Social Determinants of Health for Children Born Extremely Preterm. J Pediatr , 113443. https://doi.org/10.1016/j.jpeds.2023.113443

Shaw, R. J., Moreyra, A., Simon, S., Wharton, E., Dowtin, L. L., Armer, E., . . . Hintz, S. , V an Meurs, K. , & Horwitz, S. M. (2023). Group trauma focused cognitive behavior therapy for parents of premature infants compared to individual therapy intervention. Early Hum Dev , 181 , 105773. https://doi.org/10.1016/j.earlhumdev.2023.105773

Variane, G. F. T., Pietrobom, R. F. R., Noh, C. Y., Van Meurs, K. P. , & Chock, V. Y. (2023). Newer indications for neuromonitoring in critically ill neonates. Front Pediatr , 11 , 1111347. https://doi.org/10.3389/fped.2023.1111347

Anbazhakan, S., Rios Coronado, P. E., Sy-Quia, A. N. L., Seow, L. W., Hands, A. M., Zhao, M., . . . Pasca, A. M. , . . . & Horse, K. R. (2022). Blood flow modeling reveals improved collateral artery performance during the regenerative period in mammalian hearts. Nat Cardiovasc Res , 1 (8), 775-790. https://doi.org/10.1038/s44161-022-00114-9

July , August , September

quarter : 39

year-to-date : 130

Chitkara, R. , Bennett, M., Bohnert, J., Yamada, N. , Fuerch, J. , Halamek, L. P. , Quinn, J., . . . Gould, J. , Profit, J. , . . . & Lee, H. C. (2023). In Situ Simulation and Clinical Outcomes in Infants Born Preterm. J Pediatr , 263 , 113715. https://doi.org/10.1016/j.jpeds.2023.113715

Nyarko, S. H., Greenberg, L. T., Phibbs, C. S. , Buzas, J. S., Lorch, S. A., Rogowski, J., Saade, G. R., . . . & Boghossian, N. S. (2023). Association between stillbirth and severe maternal morbidity. Am J Obstet Gynecol . https://doi.org/10.1016/j.ajog.2023.08.029

Handley, S. C., Formanowski, B., Passarella, M., Kozhimannil, K. B., Leonard, S. A., Main, E. K., Phibbs, C. S. , & Lorch, S. A. (2023). Perinatal Care Measures Are Incomplete If They Do Not Assess The Birth Parent-Infant Dyad As A Whole. Health Aff (Millwood) , 42 (9), 1266-1274. https://doi.org/10.1377/hlthaff.2023.00398

Benitz, W. E. (2023). Perils of meta-analysis. Arch Dis Child Fetal Neonatal Ed . https://doi.org/10.1136/archdischild-2023-326132

Leonard, S. A., Formanowski, B. L., Phibbs, C. S. , Lorch, S., Main, E. K., Kozhimannil, K. B., Passarella, M., & Bateman, B. T. (2023). Chronic Hypertension in Pregnancy and Racial-Ethnic Disparities in Complications. Obstet Gynecol , 142 (4), 862-871. https://doi.org/10.1097/AOG.0000000000005342

Igbinosa, II, Leonard, S. A., Noelette, F., Davies-Balch, S., Carmichael, S. L. , Main, E., & Lyell, D. J. (2023). Racial and Ethnic Disparities in Anemia and Severe Maternal Morbidity. Obstet Gynecol , 142 (4), 845-854. https://doi.org/10.1097/AOG.0000000000005325

Yoon, J., Ong, M. K., Vanneman, M. E., Zhang, Y., Dizon, M. P., & Phibbs, C. S. (2023). Hospital and Patient Factors Affecting Veterans' Hospital Choice. Med Care Res Rev , 10775587231194681. https://doi.org/10.1177/10775587231194681

Stevenson, D. K. , Murray, J. C., Muglia, L. J., Wong, R. J., & Katz, M. (2023). Challenges to the study of gender dysphoria. Acta Paediatr , 112 (11), 2273-2275. https://doi.org/10.1111/apa.16975

Varner, M. W., Thom, E. A., Cotten, C. M., Hintz, S. R. , Page, G. P., Rouse, D. J., Mercer, B. M., . . . & Eunice Kennedy Shriver National Institute of Child Health & Human Development Maternal-Fetal Medicine Units Network Neonatal Research Network. (2023). Genetic Predisposition to Adverse Neurodevelopmental Outcome of Extremely Low Birth Weight Infants. Am J Perinatol . https://doi.org/10.1055/s-0043-1774312

Chock, V. Y. , Kirpalani, H., Bell, E. F., Tan, S., Hintz, S. R. , Ball, M. B., Smith, E., . . . Van Meurs, K. P. , Eunice Kennedy Shriver National Institute of Child, Health & Human Development Neonatal Research Network. (2023). Tissue Oxygenation Changes After Transfusion and Outcomes in Preterm Infants: A Secondary Near-Infrared Spectroscopy Study of the Transfusion of Prematures Randomized Clinical Trial (TOP NIRS). JAMA Netw Open , 6 (9), e2334889. https://doi.org/10.1001/jamanetworkopen.2023.34889

Vidavalur, R., & Bhutani, V. K. (2023). Trends in infant mortality due to haemolytic disease and other perinatal jaundice in the USA, 1999-2020. Arch Dis Child Fetal Neonatal Ed . https://doi.org/10.1136/archdischild-2023-326006

Marcone, A. L., Darmstadt, G. L. , Challamel, G. A., Mathur, M. B., & Gardner, C. D. (2023). Effects of an educational planetary plate graphic on meat consumption in a Stanford University dining hall: a randomized controlled trial. BMC Nutr , 9 (1), 106. https://doi.org/10.1186/s40795-023-00764-3

Pruitt Evans, S., Ailes, E. C., Kramer, M. R., Shumate, C. J., Reefhuis, J., Insaf, T. Z., Yazdy, M. M., Carmichael, S. L. , . . . Shaw, G. M. , . . . & National Birth Defects Prevention Study. (2023). Neighborhood Deprivation and Neural Tube Defects. Epidemiology , 34 (6), 774-785. https://doi.org/10.1097/EDE.0000000000001655

Salimi Jazi, F., Wood, L., Rafeeqi, T., Yamada, N. K. , Fuerch, J. H. , & Wall, J. K. (2023). Novel umbilical catheter securement and protection device for umbilical line securement during laparotomy. Am J Perinatol . https://doi.org/10.1055/a-2182-4221

Shaw, R. J., Givrad, S., Poe, C., Loi, E. C., Hoge, M. K., & Scala, M. (2023). Neurodevelopmental, Mental Health, and Parenting Issues in Preterm Infants. Children (Basel) , 10 (9). https://doi.org/10.3390/children10091565

Ravindra, N. G., Espinosa, C., Berson, E., Phongpreecha, T., Zhao, P., Becker, M., Chang, A. L., . . . Shaw, G. M. , . . . Stevenson, D. K. , England, S. K., & Aghaeepour, N. (2023). Deep representation learning identifies associations between physical activity and sleep patterns during pregnancy and prematurity. NPJ Digit Med , 6 (1), 171. https://doi.org/10.1038/s41746-023-00911-x

Krajewski, A. K., Patel, A., Gray, C. L., Messer, L. C., Keeler, C. Y., Langlois, P. H., Reefhuis, J., . . . Shaw, G. M. , Carmichael, S. L. , . . . & National Birth Defects Prevention Study. (2023). Is gastroschisis associated with county-level socio-environmental quality during pregnancy? Birth Defects Res . https://doi.org/10.1002/bdr2.2250

Espinosa, C., Ali, S. M., Khan, W., Khanam, R., Pervin, J., Price, J. T., Rahman, S., . . . Shaw, G. M. , Stevenson, D. K. , Darmstadt, G. L. , . . . & Angst, M. S. (2023). Comparative predictive power of serum vs plasma proteomic signatures in feto-maternal medicine. AJOG Glob Rep , 3 (3), 100244. https://doi.org/10.1016/j.xagr.2023.100244

Rose, L. A., Frymoyer, A. , Bhombal, S., & Chock, V. Y. (2023). Renal Oxygen Saturations and Acute Kidney Injury in the Preterm Infant with Patent Ductus Arteriosus. Am J Perinatol . https://doi.org/10.1055/a-2130-2269

Green, C. E., Tyson, J. E., Heyne, R. J., Hintz, S. R. , Vohr, B. R., Bann, C. M., Das, A., . . . Van Meurs, K. P. ,  . . . Eunice Kennedy Shriver National Institute of Child, Health & Human Development Neonatal Research Network. (2023). Use of term reference infants in assessing the developmental outcome of extremely preterm infants: lessons learned in a multicenter study. J Perinatol , 43 (11), 1398-1405. https://doi.org/10.1038/s41372-023-01729-x

Evenson, K. R., Mowla, S., Olshan, A. F., Shaw, G. M. , Ailes, E. C., Reefhuis, J., Joshi, N., . . . & National Birth Defects Prevention Study & Birth Defects Study To Evaluate Pregnancy exposureS. (2023). Maternal physical activity, sitting, and risk of non-cardiac birth defects. Pediatr Res . https://doi.org/10.1038/s41390-023-02768-y

Molloy, E. J., Branagan, A., Hurley, T., Quirke, F., Devane, D., Taneri, P. E., El-Dib, M., . . . Bonifacio, S. L. , . . . & Steering Group for DEFiNE. (2023). Neonatal encephalopathy and hypoxic-ischemic encephalopathy: moving from controversy to consensus definitions and subclassification. Pediatr Res . https://doi.org/10.1038/s41390-023-02775-z

Dyess, N. F., Keels, E., Myers, P., French, H., Reber, K., LaTuga, M. S., Johnston, L. C., . . . & Scala, M. (2023). Optimizing clinical care and training in the neonatal intensive care unit: the relationship between front line providers and physician trainees. J Perinatol . https://doi.org/10.1038/s41372-023-01749-7

Gould, J. B. , Bennett, M. V., Profit, J. , & Lee, H. C. (2023). Cohort selection and the estimation of racial disparity in mortality of extremely preterm neonates. Pediatr Res . https://doi.org/10.1038/s41390-023-02766-0

Abramsky, R., Acun, C., Alt, J., Aly, H., Arad, N., Baak, L. M., Bakalar, D., . . . Van Meurs, K. ,  . . . & Wustoff, C. (2023). Proceedings of the 14th International Newborn Brain Conference: Neonatal Neurocritical Care, seizures, and continuous aEEG and /or EEG monitoring. J Neonatal Perinatal Med , 16 (s1), S33-S62. https://doi.org/10.3233/NPM-239003

Dasani, R., Pai, V. V., Noh, C. Y., Vallandingham-Lee, S., Davis, A. S., & Bhombal, S. (2023). POCUS increases successful placement of peripheral arterial lines in neonates by less experienced providers. Eur J Pediatr . https://doi.org/10.1007/s00431-023-05160-4

Marc-Aurele, K., Branche, T., Adams, A., Feister, J., Boyle, K., Frontline Provider Interprofessional Writing Group, & Scala, M. (2023). Recommendations for creating a collaborative NICU environment to support teamwork and trainee education. J Perinatol . https://doi.org/10.1038/s41372-023-01756-8

Pitsava, G., Pankratz, N., Lane, J., Yang, W., Rigler, S., Shaw, G. M. , & Mills, J. L. (2023). Exome sequencing findings in children with annular pancreas. Mol Genet Genomic Med , 11 (10), e2233. https://doi.org/10.1002/mgg3.2233

Lowe, J., Bann, C. M., Dempsey, A. G., Fuller, J., Taylor, H. G., Gustafson, K. E., Watson, V. E., . . . Hintz, S. R. , Eunice Kennedy Shriver National Institute of Child Health & Human Development Neonatal Research Network. (2023). Do Bayley-III Composite Scores at 18-22 Months Corrected Age Predict Full-Scale IQ at 6-7 Years in Children Born Extremely Preterm? J Pediatr , 263 , 113700. https://doi.org/10.1016/j.jpeds.2023.113700

Petersen, J. M., Smith-Webb, R. S., Shaw, G. M. , Carmichael, S. L. , Desrosiers, T. A., Nestoridi, E., Darling, A. M.,  . . . & National Birth Defects Prevention Study. (2023). Periconceptional intakes of methyl donors and other micronutrients involved in one-carbon metabolism may further reduce the risk of neural tube defects in offspring: a United States population-based case-control study of women meeting the folic acid recommendations. Am J Clin Nutr , 118 (3), 720-728. https://doi.org/10.1016/j.ajcnut.2023.05.034

Blue, E. E., White, J. J., Dush, M. K., Gordon, W. W., Wyatt, B. H., White, P., Marvin, C. T., . . . Shaw, G. M. , . . . & Bamshad, M. J. (2023). Rare variants in CAPN2 increase risk for isolated hypoplastic left heart syndrome. HGG Adv , 4 (4), 100232. https://doi.org/10.1016/j.xhgg.2023.100232

Gao, X., Thomas, T. A., Morello-Frosch, R., Allen, A. M., Snowden, J. M., Carmichael, S. L. , & Mujahid, M. S. (2023). Neighborhood gentrification, displacement, and severe maternal morbidity in California. Soc Sci Med , 334 , 116196. https://doi.org/10.1016/j.socscimed.2023.116196

Robinson, K., Mosley, T. J., Rivera-Gonzalez, K. S., Jabbarpour, C. R., Curtis, S. W., Adeyemo, W. L., Beaty, T. H., . . . Shaw, G. M. , . . . & Leslie, E. J. (2023). Trio-based GWAS identifies novel associations and subtype-specific risk factors for cleft palate. HGG Adv , 4 (4), 100234. https://doi.org/10.1016/j.xhgg.2023.100234

Costello, E. K., DiGiulio, D. B., Robaczewska, A., Symul, L., Wong, R. J., Shaw, G. M. , Stevenson, D. K. , . . . & Relman, D. A. (2023). Abrupt perturbation and delayed recovery of the vaginal ecosystem following childbirth. Nat Commun , 14 (1), 4141. https://doi.org/10.1038/s41467-023-39849-9

Neo, D. T., Martin, C. L., Carmichael, S. L. , Gucsavas-Calikoglu, M., Conway, K. M., Evans, S. P., Feldkamp, M. L., . . . Shaw, G. M. , . . . & National Birth Defects Prevention Study. (2023). Are individual-level risk factors for gastroschisis modified by neighborhood-level socioeconomic factors? Birth Defects Res , 115 (15), 1438-1449. https://doi.org/10.1002/bdr2.2224

Weber, A. M., Guo, Y., Zhang, E., Gruber, S., Medina, A., Zhou, H., & Darmstadt, G. L. (2023). Associations of in-hospital postpartum feeding experiences with exclusive breastfeeding practices among infants in rural Sichuan, China. Int Breastfeed J , 18 (1), 34. https://doi.org/10.1186/s13006-023-00567-z

Christensen, R. D., Bahr, T. M., Wong, R. J., Vreman, H. J., Bhutani, V. K. , & Stevenson, D. K. (2023). A "Gold Standard" Test for Diagnosing and Quantifying Hemolysis in Neonates and Infants. J Perinatol . https://doi.org/10.1038/s41372-023-01730-4

Blanks, K. J. H., Musaba, M. W., Ren, L., Burgoine, K., Mukunya, D., Clarke, A., . . . & Darmstadt, G. L. (2023). Neonatal emollient therapy and massage practices in Africa: a scoping review. Int Health . https://doi.org/10.1093/inthealth/ihad052

Crawford, N., Prendergast, D., Oehlert, J. W., Shaw, G. M. , Stevenson, D. K. , Rappaport, N., Sirota, M., . . . & Sondheimer, N. (2023). Corrigendum to Divergent Patterns of Mitochondrial and Nuclear Ancestry Are Associated with the Risk for Preterm Birth [The Journal of Pediatrics 194(2018):40-46.e4]. J Pediatr , 261 , 113345. https://doi.org/10.1016/j.jpeds.2023.01.017

October ,  November ,  December

quarter : 35

year-to-date : 165

Nawathe, P. A., Kessler, D. O., Yurasek, G., Sawyer, T. L., Halamek, L. P. , Stone, K., Ramachandra, G., . . . & Calhoun, A. (2023). The Need for Simulation-Based Procedural Skills Training to Address Proposed Changes in Accreditation Council for Graduate Medical Education Requirements for Pediatric Residency Programs. Simul Healthc , 18 (6), 416-418. https://doi.org/10.1097/SIH.0000000000000757

Anderson, C. L., Toole, R., Schmidt, C., & Darmstadt, G. L. (2023). Strengthening theories of change in women's group interventions to improve learning. J Glob Health , 13 , 04098. https://doi.org/10.7189/jogh.13.04098

Yoon, J., Phibbs, C. S. , Ong, M. K., Vanneman, M. E., Chow, A., Redd, A., Kizer, K. W., . . . & Zhang, Y. (2023). Outcomes of Veterans Treated in Veterans Affairs Hospitals vs Non-Veterans Affairs Hospitals. JAMA Netw Open , 6 (12), e2345898. https://doi.org/10.1001/jamanetworkopen.2023.45898

DeZure, C. (2023). Updated Clinical Practice Guidelines for Management of Hyperbilirubinemia in Infants Born at 35 Weeks or More Gestation. Pediatr Ann , 52 (12), e436-e439. https://doi.org/10.3928/19382359-20231016-07

Krzyzanski, W., Wintermark, P., Annaert, P., Groenendaal, F., Sahin, S., Oncel, M. Y., Armangil, D., . . . Frymoyer, A. , Chock, V. Y. , . . . & Allegaert, K. (2023). A Population Model of Time-Dependent Changes in Serum Creatinine in (Near)term Neonates with Hypoxic-Ischemic Encephalopathy During and After Therapeutic Hypothermia. AAPS J , 26 (1), 4. https://doi.org/10.1208/s12248-023-00851-0

Berkowitz, R. L., Kan, P., Gao, X., Hailu, E. M., Board, C., Lyndon, A., Mujahid, M., & Carmichael, S. L. (2023). Assessing the relationship between census tract rurality and severe maternal morbidity in California (1997-2018). J Rural Health . https://doi.org/10.1111/jrh.12814

El Ayadi, A. M., Lyndon, A., Kan, P., Mujahid, M. S., Leonard, S. A., Main, E. K., & Carmichael, S. L. (2024). Trends and Disparities in Severe Maternal Morbidity Indicator Categories during Childbirth Hospitalization in California from 1997 to 2017. Am J Perinatol . https://doi.org/10.1055/a-2223-3520

Malaker, R., Hasanuzzaman, M., Hooda, Y., Rahman, H., Chandra Das, R., Kanon, N., Saha, S., . . . Darmstadt, G. L. , . . . & Saha, S. K. (2024). Effectiveness of ten-valent pneumococcal conjugate vaccine on invasive pneumococcal disease among children <2 years old: A prospective population-based study in rural Bangladesh. Vaccine , 42 (2), 255-262. https://doi.org/10.1016/j.vaccine.2023.12.007

Leonard, S. A., Phibbs, C. S. , Main, E. K., Kozhimannil, K. B., & Bateman, B. T. (2024). In Reply. Obstet Gynecol , 143 (1), e18-e19. https://doi.org/10.1097/AOG.0000000000005457

Razdan, S., Davis, A. S. , Tidmarsh, G., Hintz, S. R. , Grimm, P. C., & Chock, V. Y. (2024). Angiotensin-II Use for Refractory Hypotension in an Infant With Bilateral Renal Agenesis. Pediatrics , 153 (1). https://doi.org/10.1542/peds.2023-062128

Veazie, P., Intrator, O., Kinosian, B., & Phibbs, C. S. (2023). Better performance for right-skewed data using an alternative gamma model. BMC Med Res Methodol , 23 (1), 298. https://doi.org/10.1186/s12874-023-02113-1

Petersen, J. M., Kahrs, J. C., Adrien, N., Wood, M. E., Olshan, A. F., Smith, L. H., Howley, M. M., . . . Shaw, G. M. , . . . & National Birth Defects Prevention Study. (2023). Bias analyses to investigate the impact of differential participation: Application to a birth defects case-control study. Paediatr Perinat Epidemiol . https://doi.org/10.1111/ppe.13026

Molloy, E. J., El-Dib, M., Soul, J., Juul, S., Gunn, A. J., Bender, M., Gonzalez, F., . . . Bonifacio, S. L. , Newborn Brain Society Guidelines & Publications Committee. (2023). Neuroprotective therapies in the NICU in preterm infants: present and future (Neonatal Neurocritical Care Series). Pediatr Res . https://doi.org/10.1038/s41390-023-02895-6

Freccero, A., Scala, M. , McLeod, K. A., Donahue, B., Webb, M., Briggs, M., Najm, I., . . . & Nasr, A. (2024). The Safety of Body Wraps on Skin-to-Skin Care in the Neonatal Population: A Pilot Study. Adv Neonatal Care , 24 (1), E11-E19. https://doi.org/10.1097/ANC.0000000000001133

Golob, J. L., Oskotsky, T. T., Tang, A. S., Roldan, A., Chung, V., Ha, C. W. Y., Wong, R. J., . . . Stevenson, D. K. , . . . & Sirota, M. (2024). Microbiome preterm birth DREAM challenge: Crowdsourcing machine learning approaches to advance preterm birth research. Cell Rep Med , 5 (1), 101350. https://doi.org/10.1016/j.xcrm.2023.101350

Kaluarachchi, D. C., Rysavy, M. A., Carper, B. A., Chock, V. Y. , Laughon, M. M., Backes, C. H., Colaizy, T. T., . . . & McNamara, P. J. (2024). Secular Trends in Patent Ductus Arteriosus Management in Infants Born Preterm in the National Institute of Child Health and Human Development Neonatal Research Network. J Pediatr , 266 , 113877. https://doi.org/10.1016/j.jpeds.2023.113877

Liu, L., Wu, Y., Xian, X., Feng, J., Mao, Y., Balakrishnan, S., Weber, A. M., Darmstadt, G. L. , . . . & Rozelle, S. (2023). In-Hospital Formula Feeding Hindered Exclusive Breastfeeding: Breastfeeding Self-Efficacy as a Mediating Factor. Nutrients , 15 (24). https://doi.org/10.3390/nu15245074

Bhutani, V. K. , Vidavalur, R., & Wong, R. J. (2023). Advances to diminish global newborn kernicterus mortality. J Perinatol . https://doi.org/10.1038/s41372-023-01862-7

Razdan, S., Hedli, L. C., Sigurdson, K., Profit, J. , & Morton, C. H. (2023). Disparity drivers, potential solutions, and the role of a health equity dashboard in the neonatal intensive care unit: a qualitative study. J Perinatol . https://doi.org/10.1038/s41372-023-01856-5

Williford, E. M., Yang, W., Howley, M. M., Ma, C., Collins, R. T., Weber, K. A., Heinke, D., . . . Shaw, G. M. , & National Birth Defects Prevention Study. (2024). Factors associated with infant sex and preterm birth status for selected birth defects from the National Birth Defects Prevention Study, 1997-2011. Birth Defects Res , 116 (1), e2294. https://doi.org/10.1002/bdr2.2294

Glass, H. C., Numis, A. L., Comstock, B. A., Gonzalez, F. F., Mietzsch, U., Bonifacio, S. L. , Massey, S., . . . Van Meurs, K. P. , . . . & Wusthoff, C. J. (2023). Association of EEG Background and Neurodevelopmental Outcome in Neonates With Hypoxic-Ischemic Encephalopathy Receiving Hypothermia. Neurology , 101 (22), e2223-e2233. https://doi.org/10.1212/WNL.0000000000207744

Zhao, H., Wong, R. J., & Stevenson, D. K. (2023). The placental vasculature is affected by changes in gene expression and glycogen-rich cells in a diet-induced obesity mouse model. PLoS One , 18 (11), e0294185. https://doi.org/10.1371/journal.pone.0294185

Variane, G. F. T., Dahlen, A., Pietrobom, R. F. R., Rodrigues, D. P., Magalhaes, M., Mimica, M. J., Llaguno, N. S., . . . & Van Meurs, K. P. (2023). Remote Monitoring for Seizures During Therapeutic Hypothermia in Neonates With Hypoxic-Ischemic Encephalopathy. JAMA Netw Open , 6 (11), e2343429. https://doi.org/10.1001/jamanetworkopen.2023.43429

Dubner, S. E., Rickerich, L., Bruckert, L., Poblaciones, R. V., Sproul, D., Scala, M. , Feldman, H. M., & Travis, K. E. (2023). Early, low-dose hydrocortisone and near-term brain connectivity in extremely preterm infants. Pediatr Res . https://doi.org/10.1038/s41390-023-02903-9

Dizon, M. P., Kizer, K. W., Ong, M. K., Phibbs, C. S. , Vanneman, M. E., Wong, E. P., Zhang, Y., & Yoon, J. (2023). Differences in use of Veterans Health Administration and non-Veterans Health Administration hospitals by rural and urban Veterans after access expansions. J Rural Health . https://doi.org/10.1111/jrh.12812

Mietzsch, U., Kolnik, S. E., Wood, T. R., Natarajan, N., Gonzalez, F. F., Glass, H., Mayock, D. E., Bonifacio, S. L. , Van Meurs, K. , . . . & Group, H. T. S. (2023). Evolution of the Sarnat exam and association with 2-year outcomes in infants with moderate or severe hypoxic-ischaemic encephalopathy: a secondary analysis of the HEAL Trial. Arch Dis Child Fetal Neonatal Ed . https://doi.org/10.1136/archdischild-2023-326102

Weigel, N., Hintz, S. , Kaplinski, M., Barth, R., Balakrishnan, K., Panelli, D., Ma, M., & Chitkara, R. (2023). Prenatal Diagnosis and Postnatal Management of a Fetal Pericardial Mass. Neoreviews , 24 (10), e683-e689. https://doi.org/10.1542/neo.24-10-e683

Lin, Y. C., Ni, J., Swaminathan, G., Khalid, A., Barakat, M. T., Frymoyer, A. R. , Tsai, C. Y., . . . & Husain, S. Z. (2023). Rectal administration of tacrolimus protects against post-ERCP pancreatitis in mice. Pancreatology , 23 (7), 777-783. https://doi.org/10.1016/j.pan.2023.09.080

Qu, F., Brough, S. C., Michno, W., Madubata, C. J., Hartmann, G. G., Puno, A., Drainas, A. P., . . . Pasca, A. M. , & Sage, J. (2023). Crosstalk between small-cell lung cancer cells and astrocytes mimics brain development to promote brain metastasis. Nat Cell Biol , 25 (10), 1506-1519. https://doi.org/10.1038/s41556-023-01241-6

Lapcharoensap, W., Bennett, M., Xu, X., Lee, H. C., Profit, J. , & Dukhovny, D. (2024). Quality, outcome, and cost of care provided to very low birth weight infants in California. J Perinatol , 44 (2), 224-230. https://doi.org/10.1038/s41372-023-01792-4

DeZure, C. (2023). Race-Based Medicine Is Racist. Pediatr Ann , 52 (10), e365-e367. https://doi.org/10.3928/19382359-20230829-05

Bonifacio, S. L. , & de Vries, L. S. (2023). Scalp Swelling, a Proxy for "Birth Trauma," Is Not Associated With Neonatal Brain Injury. Neurology , 101 (23), 1037-1038. https://doi.org/10.1212/WNL.0000000000208025

Serenska, A., Sarnquist, C. C., & Darmstadt, G. L. (2023). Variation in rates of sexual assault crisis counsellor usage during forensic examination in California: an observational study. BMJ Open , 13 (10), e072635. https://doi.org/10.1136/bmjopen-2023-072635

Anjur, K. I., & Darmstadt, G. L. (2023). Separation of Maternal and Newborn Care in US Hospitals: A Systemic Threat to Survival, Health and Well-Being. Health Syst Reform , 9 (1), 2267255. https://doi.org/10.1080/23288604.2023.2267255

Rios Coronado, P. E., Zanetti, D., Zhou, J., Naftaly, J. A., Prabala, P., Kho, P. F., Martinez Jaimes, A. M., . . . Pasca, A. M. , . . . & Assimes, T. L. (2023). CXCL12 regulates coronary artery dominance in diverse populations and links development to disease. medRxiv . https://doi.org/10.1101/2023.10.27.23297507

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Women in Neonatology: 2022

Loading... Editorial 10 October 2023 Editorial: Women in Neonatology 2022 Britt Nakstad  and  Ju-Lee Oei 674 views 0 citations

neonatal research topics 2022

Original Research 19 September 2023 Comparison of simultaneous auscultation and ultrasound for clinical assessment of bowel peristalsis in neonates Archana Priyadarshi ,  8 more  and  Sheryl Rogerson 1,333 views 0 citations

Original Research 14 June 2023 Regional references vs. international standards for assessing weight and length by gestational age in Lithuanian neonates Ruta Morkuniene ,  6 more  and  Janina Tutkuviene 1,158 views 0 citations

Review 15 May 2023 Leveraging the placenta to advance neonatal care Karen K. Mestan ,  5 more  and  Mana Parast 1,776 views 2 citations

Loading... Review 28 April 2023 Neonatologist-performed point-of-care abdominal ultrasound: What have we learned so far? Archana Priyadarshi ,  7 more  and  Mark Tracy 3,605 views 0 citations

Review 25 April 2023 Neonatal warming devices: What can be recommended for low-resource settings when skin-to-skin care is not feasible? Michiko Kyokan ,  2 more  and  Riccardo E. Pfister 2,574 views 0 citations

Original Research 16 March 2023 Use of eye-tracking to evaluate human factors in accessing neonatal resuscitation equipment and medications for advanced resuscitation: A simulation study Linda Gai Rui Chen  and  Brenda Hiu Yan Law 1,282 views 1 citations

Loading... Systematic Review 16 January 2023 Fetal–neonatal exposure to antibiotics and NEC development: A systematic review and meta-analysis Daphne H. Klerk ,  3 more  and  Elisabeth M. W. Kooi 2,827 views 5 citations

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Editorial: Women in Neonatology 2022

Britt nakstad.

1 Department of Paediatrics and Adolescent Health, University of Botswana, Gaborone, Botswana

2 Division of Paediatric and Adolescent Medicine, Institute of Clinical Medicine, University of Oslo, Oslo, Norway

3 Department of Newborn Care, Royal Hospital for Women, Randwick, NSW, Australia

4 Faculty of Medicine and Healthy, School, of Paediatrics, University of New South Wales, Randwick, NSW, Australia

Editorial on the Research Topic Women in Neonatology 2022

The Frontiers Research Topic of Women in Neonatology 2022 is an article collection in Frontiers in Pediatrics that aims to support gender equity, and hopefully raise awareness and promote the strengths of women in research, education, clinical care, and advocacy in the field of neonatal-perinatal medicine. Our community is richer and possibilities greater when we each actively advocate for and work towards equitable, diverse, and inclusive collaborations in the clinical setting and in research related to neonatology. We also sought to support and encourage the next generation of women and girls to pursue careers in research and to raise the experience necessary for future leadership. The purpose of this mission is driven by the recognition that gender equality in science is essential to ensure sustainable development as highlighted by UNESCO. Currently, less than 30% of scientists are women and to truly reduce this disparity, women must be encouraged to engage in STEM (Science, Technology, Engineering and Mathematics) careers ( https://uis.unesco.org/en/topic/women-science ).

In this collection of articles, the first or last author is a woman with expertise in neonatology. We received 11 submissions of which 4 were rejected. This collection includes 7 articles demonstrating the diversity of neonatology-related research led by women.

Chen and Law use visual attention analysis to study human factors in neonatal resuscitation preparations. They perform a 2-site randomized cross-over simulation study with eye-tracking glasses and randomize two methods to prepare epinephrine doses. Post-simulation, participants complete surveys and semi-structured interviews while viewing eye-tracked videos of their performance. Eye-tracked simulations provide human factors assessment of emergency neonatal code carts and epinephrine preparation and may help to choose the best technique.

Klerk et al. present a systematic review and meta-analysis on whether exposure to antibiotics is associated with a risk of necrotizing enterocolitis (NEC) in preterms. They search MEDLINE and EMBASE between 1990 and 2021 and find 370 papers acceptable for screening of outcomes. Their findings suggest an association between third-trimester maternal antibiotics and decreased risk of NEC. However, an increased risk of NEC was associated with prolonged use of empirical antibiotics that are known to reduce and unfavorably change microbiota diversity. The authors also find that prolonging empiric antibiotic treatment after birth could be associated with an increased risk of NEC. Based on these results, they advise using empiric antibiotics for as short a duration as possible and specifically, for newborn infants, to evaluate the need for guidelines beyond 36–48 h.

Kyokan et al. review evidence-based guidance for healthcare workers and stakeholders in choosing the most appropriate warming devices for clinically unstable neonates whose parents or family members cannot offer skin-to-skin care. The authors conduct a rapid review that includes a search for systematic reviews as well as randomized and quasi-randomized controlled trials that include searches for neonatal thermal care guidelines for the use of warming devices in low-resource settings. The search also includes requirements for resources and specifications of warming devices used in the nursery. The authors find no differences in the effectiveness of radiant warmers, incubators, and heated water-filled mattresses in maintaining body temperature but find that insensible water loss increases with radiant warmers. Seven guidelines covering the use of neonatal warming devices show no consensus about the choice of warming methods for clinically unstable neonates. They point out that radiant warmers allow fast access to the baby during the delivery period but in the unit, warming mattresses are more effective and economical as they are low-cost, effective, and low-electricity consumption devices that can be used for prolonged periods. For convalescing infants, incubators are best, especially for very premature infants where there is a prolonged risk of large insensible water loss for several weeks.

Mestan et al. review evidence to determine the relationship between placental dysfunction and placental injury impact on the fetus and newborn infant. This is a topic of growing interest in neonatal disease research. A search in Pubmed on the placenta and neonatal outcomes shows the publication of 5,741 papers and almost half during the last 7 years. The authors summarize the most common neonatal diagnoses that have been associated with placental dysfunction and discuss how recent technological advances may allow a shift to use valuable information from the placenta to guide neonatal management more effectively and to improve neonatal outcomes. The authors propose new ways of clinical management in which information from the placenta, with evaluation of the placenta histology as well through closely related biomarkers in maternal blood/urine, cord blood, and postnatal biospecimens, can be related to neonatal management. They conclude that opportunities to advance neonatal care using information related to the placenta with more rapid delivery of information to clinicians in NICU settings would lead to a rapidly evolving approach to bedside diagnosis and more timely management of multiple problems in the NICU.

Morkuniene et al. compare the applicability of regional and global standards to the Lithuanian newborn population by sex and gestational age, based on the prevalence of small or large for gestational age (SGA/LGA). They perform a retrospective analysis from 1995 to 2015 (618,235 newborns of 24–42 gestational weeks). They conclude that the regional population-based growth references represent the Lithuanian neonatal weight and length much more accurately than the global standard INTERGROWTH21st (IG-21, https://intergrowth21.tghn.org/ ), which provides the prevalence rates for SGA/LGA that differ from the true values.

Priyadarshi et al. review point-of-care bowel ultrasound appearances of the neonatal bowel in necrotizing enterocolitis (NEC) and provide several photos and figures to ease the reading and understanding. Taken together this is a useful tool for clinicians. The authors compare NEC findings to those seen in midgut-volvulus, obstructive intestinal conditions such as milk-curd obstruction, and slow gut motility in preterm infants on continuous positive airway pressure (CPAP) for CPAP belly syndrome. Priyadarshi et al. argue that bowel sonography is helpful when the diagnosis is unclear and NEC cannot be excluded. They propose that NEC is often over-diagnosed, due to a lack of useful biomarkers and the fact that the clinical presentation is similar to other neonatal conditions like sepsis. Thus, the assessment of the bowel using real-time ultrasound would allow clinicians to determine the timing of re-initiation of feeds and would also be reassuring based on specific typical bowel characteristics visualized on the ultrasound.

A second article from Priyadarshi et al. assesses, through prospective observations, bowel health in newborn infants between 27 and 43 weeks gestation. They compare conventional bowel sound auscultation using recordings with an electronic stethoscope, continuous 60-s recordings of bowel sound at a set region over the abdomen, to real-time bowel motility visualized by bowel ultrasound. Both methods are performed in 30 neonates on full enteral feeds without bowel pathology. A second investigator, blinded to the auscultation findings by the first investigator, conducts bowel ultrasound images using the same 12l Linear US probe. All recordings are analyzed for bowel peristalsis by the two methods. The authors find no correlation and different median time of peristalsis with ultrasound (58%), compared to acoustic assessment (88.3%, p  < 0.002). Their findings call for better innovative methods to characterize bowel sounds in neonates, by integrating acoustic mapping with sonographic detection of bowel peristalsis, maybe using artificial intelligence.

This article collection is inspiring, informative, and substantially advances knowledge. It offers unique views of many aspects of neonatal care, theory, research, and methodology. Most importantly, it is a representation of the possibilities that women bring to the field of research and clinical experience in neonatology, one of the most research-active areas in pediatrics. This is a diverse and cross-cultural collection but may under-represent the potential of women in the global neonatal research community. We encourage women, especially those in lower-resourced settings and from countries where English is not the primary language, to actively advocate for and work towards equitable, diverse, and inclusive environments to advance clinical work and research in newborn medicine.

Author contributions

BN: Conceptualization, Writing – original draft. JO: Conceptualization, Writing – original draft.

Conflict of interest

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

The author(s) declared that they were an editorial board member of Frontiers, at the time of submission. This had no impact on the peer review process and the final decision.

Publisher's note

All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.

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Back to Journals » Research and Reports in Neonatology

neonatal research topics 2022

Research and Reports in Neonatology

Issn: 1179-9935.

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neonatal research topics 2022

Number of Seizures and Associated Factors Among Neonates with Perinatal Asphyxia Admitted to Neonatal Intensive Care Unit in Selected Comprehensive Specialized Hospitals of Amhara Region, Northwest Ethiopia,2023. A Poisson Regression Analysis

Gedefaw GD, Lakew AM, Gebreegzabiher ZA, Daka DT, Hailu MK, Wondie WT, Ayenew ME, Zemariam AB, Legesse BT, Worku DT, Abate AT

Research and Reports in Neonatology 2024 , 14:97-108

Published Date: 31 May 2024

Cerebral Near‐Infrared Spectroscopy Use in Neonates: Current Perspectives

Vesoulis ZA, Sharp DP, Lalos N, Swofford DP, Chock VY

Research and Reports in Neonatology 2024 , 14:85-95

Published Date: 10 May 2024

Mortality Among Low Birth Weight Neonates on Parenteral Feeding: A Prospective Follow-Up Study

Mislu E, Arage MW, Kumsa H, Terefe A

Research and Reports in Neonatology 2024 , 14:67-84

Published Date: 3 May 2024

Vitamin D Status of Preterm Newborns at Approximately 4 Weeks of Age in Shenzhen, China: A Retrospective Observational Cohort Study Conducted Across Two Centers

Guo Y, Yu Z, Tu H, Zheng B, Li J, Liu Y

Research and Reports in Neonatology 2024 , 14:59-66

Published Date: 6 March 2024

Obstacles to the Early Diagnosis and Management of Patent Ductus Arteriosus

Gowda SH, Philip R, Weems MF

Research and Reports in Neonatology 2024 , 14:43-57

Published Date: 29 February 2024

Congenital Malaria in a 20-Day-Old Neonate: A Case Report and Literature Review

Regasa MT, Shibiru T, Tilahun T, Bayisa G, Negari GK

Research and Reports in Neonatology 2024 , 14:39-42

Published Date: 26 February 2024

Ethmocephaly, the Rarest Sub-Type of Holoprosencephaly: A Case Report

Geta G, Mesfin T, Tsegaye M, Bobe T, Bikila B, Hailu FC, Dejene T

Research and Reports in Neonatology 2024 , 14:35-38

Published Date: 2 February 2024

Prevalence, Prevention and Management of Bronchopulmonary Dysplasia

Gilfillan MA, Mejia MJ, Bhandari V

Research and Reports in Neonatology 2024 , 14:1-33

Published Date: 4 January 2024

Hydrops fetalis: Incidence, Etiologies, Management Strategies, and Outcomes

Younge T, Ottolini KM, Al-Kouatly HB, Berger SI

Research and Reports in Neonatology 2023 , 13:81-92

Published Date: 20 December 2023

The Global Crisis of Congenital Syphilis: Vulnerable and Disenfranchised Women Most at Risk

Moore A, Freyne B, Nourse C

Research and Reports in Neonatology 2023 , 13:65-79

Published Date: 7 December 2023

Updated Perspectives on the Diagnosis and Management of Neonatal Invasive Candidiasis

Daniel K, Greenberg RG, Boutzoukas A, Katakam L

Research and Reports in Neonatology 2023 , 13:45-63

Published Date: 9 November 2023

Magnitude of Neonatal Admission Diagnosis and Associated Factors at Selected Hospitals in Wollo, Northeast Ethiopia

Asmamaw SD, Getachew S, Demeke T, Hankarso H, Alemnew B, Wedajo S, Molla A

Research and Reports in Neonatology 2023 , 13:29-44

Published Date: 8 November 2023

Neonatal Hydrometrocolpos Secondary to Imperforate Hymen Presented with Acute Urinary Retention: Case Report

Tegene D, Assefa T, Edris A

Research and Reports in Neonatology 2023 , 13:23-28

Published Date: 2 November 2023

neonatal research topics 2022

Antenatal Kratom Exposure: Literature Review and Clinical Management Recommendations

Research and Reports in Neonatology 2023 , 13:15-21

Published Date: 4 October 2023

Lived Experience of Mothers Having Preterm Newborns in a Neonatal Intensive Care Unit at Wolaita Sodo University Comprehensive Specialized Hospital Southern Ethiopia: A Phenomenological Study

Mimani Minuta W, Lera T, Haile D, Badacho AS, Bekele B, Gezume Ganta A, Nigussie Bolado G, Bashe B

Research and Reports in Neonatology 2023 , 13:1-14

Published Date: 2 August 2023

Examining Practice Variation Used for Packed Red Blood Cell Transfusions for Preterm Infants in Neonatal Intensive Care Units Across the United States

Everhart KC, Donevant SB, Iskersky VN, Wirth MD, Dail RB

Research and Reports in Neonatology 2022 , 12:43-48

Published Date: 7 October 2022

Neonatal Sucking Blister and Sucking Pads: Coexisting Simultaneously in a 24 Hour Old Newborn

Arega G, Admasse SD, Alemneh D

Research and Reports in Neonatology 2022 , 12:39-41

Published Date: 23 August 2022

Saving the Lives of Asphyxiated Newborns in Public Health Facilities: An Implementation Research

Shinde S, Tiruneh F, Abdissa D

Research and Reports in Neonatology 2022 , 12:31-38

Published Date: 4 August 2022

Determinants of Low Birth Weight Among Newborns Delivered in Silte Zone Public Health Facilities, Southern Ethiopia: A Case-Control Study

Seid S, Wondafrash B, Gali N, Ali A, Mohammed B, Kedir S

Research and Reports in Neonatology 2022 , 12:19-29

Published Date: 2 July 2022

neonatal research topics 2022

Advancing Clinical Decision Support Systems for the Management of Neonatal Nutrition: Barriers to Implementation

neonatal research topics 2022

Falciglia GH, Sierra-Fernandez H, Freeman M, Healy D, Wicks JS, Robinson DT

Research and Reports in Neonatology 2022 , 12:11-18

Published Date: 20 June 2022

Parental Satisfaction with Neonatal Intensive Care Unit Services and Associated Factors in Jimma University Medical Center, Ethiopia

Adal Z, Atomsa G, Tulu G

Research and Reports in Neonatology 2022 , 12:1-10

Published Date: 27 April 2022

Acute Management of Intraperitoneal Extravasation of Total Parenteral Nutrition (TPN) in a Very Preterm Infant: Case Report and Literature Review

Majid A, Barrett J, Meyer MP

Research and Reports in Neonatology 2021 , 11:77-81

Published Date: 27 November 2021

Impacts of Hypoglycemia in At-Risk Infants on Admissions to Level-3 Neonatal Units in a Tertiary-Care Hospital

Alasaad H, Beyyumi E, Zoubeidi T, Khan N, Abu-Sa’da O, Khassawneh M, Souid AK

Research and Reports in Neonatology 2021 , 11:67-75

Published Date: 16 November 2021

Determinants of Perinatal Mortality in Public Hospitals of Iluu Abbaa Boor Oromia Region, South West Ethiopia, 2019: Unmatched Case–Control Study

Geda A, Shemsu S, Debalke R

Research and Reports in Neonatology 2021 , 11:57-66

Published Date: 3 June 2021

The Effect of Admission Hypothermia for Neonatal Death Among Neonates Admitted to Neonatal Intensive Care Unit at Sheik Hassan Yabare Jigjiga University Referral Hospital in Jigjiga City, Somali Region, Eastern Ethiopia

Ibrahim AM, Farah AM, Osman MO, Hashi A

Research and Reports in Neonatology 2021 , 11:43-55

Published Date: 16 April 2021

Prevalence and Determinants of Appropriate Child Feeding Practice Among Mothers Having Children with and without Diarrhea Aged 6–23 Months in Debre Berhan Town, Ethiopia

Research and Reports in Neonatology 2021 , 11:35-42

Published Date: 1 March 2021

Preterm Birth and Associated Factors Among Mothers Who Gave Birth in Fafen Zone Public Hospitals, Somali Regional State, Eastern Ethiopia

Muhumed II, Kebira JY, Mabalhin MO

Research and Reports in Neonatology 2021 , 11:23-33

Published Date: 23 February 2021

Determinants of Neonatal Hypothermia Among Babies Born in Public Hospitals of West Shewa Zone of Oromia Regional State, Ethiopia: Unmatched Case–Control Study

Seifu B, Belema D, Mamo K, Bulto GA

Research and Reports in Neonatology 2021 , 11:13-21

Published Date: 22 February 2021

Magnitude and Determinants of Immediate Adverse Neonatal Outcomes Among Babies Born by Cesarean Section in Public Hospitals in Harari Region, Eastern Ethiopia

Abdullahi YY, Assefa N, Roba HS

Research and Reports in Neonatology 2021 , 11:1-12

Published Date: 12 February 2021

Penile Injury During Ritual Circumcision

Ahmed F, Al-Wageeh S, Al-Shami E, Al-Naggar K, Askarpour MR, Naji M

Research and Reports in Neonatology 2020 , 10:95-99

Published Date: 24 November 2020

Perlman Syndrome with Deletion of DIS3L2 Gene

Salameh K, Viswanathan B, Nawaz Z, Habboub L, Tomerak A, Pattuvalappil R

Research and Reports in Neonatology 2020 , 10:89-93

Published Date: 23 October 2020

Knowledge Outcome of Helping Babies Breathe Training in Southern Nations, Nationalities and People’s Region, Ethiopia: A Pre- and Post-Test Study

Gamtessa LC, Kebede KM

Research and Reports in Neonatology 2020 , 10:81-88

Published Date: 2 October 2020

Bronchopulmonary Dysplasia: An Overview

Gisondo CM, Donn SM

Research and Reports in Neonatology 2020 , 10:67-79

Published Date: 25 September 2020

Growth Velocity and Factors Associated with Poor Postnatal Growth Rate Among Preterm Infants at KCMC: A Prospective Cohort Study

Mlay IE, Mchaile DN, Shayo AM

Research and Reports in Neonatology 2020 , 10:59-66

Published Date: 23 September 2020

Mother’s Knowledge of Neonatal Danger Signs and Health-Seeking Practices and Associated Factors in Debretabor, Northwest Ethiopia: A Community-Based Cross-Sectional Study

Kebede AA, Cherkos EA, Taye EB

Research and Reports in Neonatology 2020 , 10:47-58

Published Date: 10 September 2020

Poor Universal Coverage of Immediate Essential Newborn Care at Hospitals of Wollega Zones, The Case of Western Ethiopia

Kasaye HK, Yilma MT, Bobo FT, Fekadu G

Research and Reports in Neonatology 2020 , 10:37-46

Published Date: 9 September 2020

The Role of Plasma Lactate Dehydrogenase Testing in the Prediction of Severe Conditions in Newborn Infants: A Prospective Study

Van Anh TN, Kiem Hao T, Huu Hoang H

Research and Reports in Neonatology 2020 , 10:31-35

Published Date: 3 August 2020

Individualizing Oral Feeding Assessment and Therapies in the Newborn

Azuma D, Maron JL

Research and Reports in Neonatology 2020 , 10:23-30

Published Date: 20 May 2020

Neonatal (and Infant) Coarctation of the Aorta: Management Challenges

neonatal research topics 2022

Research and Reports in Neonatology 2020 , 10:11-22

Published Date: 18 February 2020

Time to Death and its Predictors among Neonates Admitted in the Intensive Care Unit of the University of Gondar Comprehensive Specialized Hospital, Northwest Ethiopia

Gudayu TW, Zeleke EG, Lakew AM

Research and Reports in Neonatology 2020 , 10:1-10

Published Date: 29 January 2020

Pulmonary function and systolic blood pressure in very low birth weight infants at 34–36 weeks of corrected age

Gievers LL, Jenkins RD, Laird A, Macedo MC, Schilling D, McEvoy CT

Research and Reports in Neonatology 2019 , 9:21-30

Published Date: 13 September 2019

Neonatal sepsis biomarkers: where are we now?

Gilfillan M, Bhandari V

Research and Reports in Neonatology 2019 , 9:9-20

Published Date: 14 March 2019

Neonatal sepsis and associated factors among newborns in hospitals of Wolaita Sodo Town, Southern Ethiopia

Mersha A, Worku T, Shibiru S, Bante A, Molla A, Seifu G, Huka G, Abrham E, Teshome T

Research and Reports in Neonatology 2019 , 9:1-8

Published Date: 17 January 2019

Incontinentia pigmenti in a term neonate: an atypical presentation

Gottimukkala SB, Jagalasar M, Sethuraman G, Kitchanan S

Research and Reports in Neonatology 2018 , 8:65-67

Published Date: 24 October 2018

Quantification of nutritive sucking among preterm and full-term infants

neonatal research topics 2022

Scherman A, Wiedrick J, Lang WC, Rdesinski RE, Lapidus J, McEvoy C, Abu-Shamsieh A, Buckley S, Rogers B, Buist N

Research and Reports in Neonatology 2018 , 8:53-63

Published Date: 8 October 2018

Current perspectives and practices of newborn vitamin K administration in low and middle income countries

Coffey PS, Gerth-Guyette E

Research and Reports in Neonatology 2018 , 8:45-51

Published Date: 5 April 2018

Acute bilirubin encephalopathy and its progression to kernicterus: current perspectives

Usman F, Diala UM, Shapiro SM, Le Pichon JB, Slusher TM

Research and Reports in Neonatology 2018 , 8:33-44

Published Date: 7 March 2018

Managing neonatal bowel obstruction: clinical perspectives

neonatal research topics 2022

Desoky SM, Kylat RI, Udayasankar U, Gilbertson-Dahdal D

Research and Reports in Neonatology 2018 , 8:19-32

Published Date: 5 February 2018

Trend of head circumference as a predictor of microcephaly among term infants born at a regional center in Malaysia between 2011-2015

Sutan R, Yeong ML, Mahdy ZA, Shuhaila A, Rohana J, Ishak S, Shamsuddin K, Ismail A, Idris IB, Sulong S

Research and Reports in Neonatology 2018 , 8:9-17

Published Date: 25 January 2018

Neonatal periventricular leukomalacia: current perspectives

Ahya KP, Suryawanshi P

Research and Reports in Neonatology 2018 , 8:1-8

Published Date: 10 January 2018

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  • Introduction
  • Conclusions
  • Article Information

a Patients could be excluded based on more than 1 criterion.

b Enrolled in the non–renal agenesis (other cause of fetal kidney failure) group of the RAFT trial, in which recruitment is ongoing.

eAppendix 1. RAFT centers and participants

eAppendix 2. Technical details of serial amnioinfusions

eTable. Postnatal respiratory and dialysis support in neonates and infants

Trial Protocol

Statistical Analysis Plan

Data Sharing Statement

  • Bilateral Renal Agenesis—Interpreting the RAFT Trial JAMA Editorial December 5, 2023 Cynthia Gyamfi-Bannerman, MD, MS; Krishelle Marc-Aurele, MD; Karen Mestan, MD, MS

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Miller JL , Baschat AA , Rosner M, et al. Neonatal Survival After Serial Amnioinfusions for Bilateral Renal Agenesis : The Renal Anhydramnios Fetal Therapy Trial . JAMA. 2023;330(21):2096–2105. doi:10.1001/jama.2023.21153

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Neonatal Survival After Serial Amnioinfusions for Bilateral Renal Agenesis : The Renal Anhydramnios Fetal Therapy Trial

  • 1 Center for Fetal Therapy, Department of Gynecology and Obstetrics, Johns Hopkins University, Baltimore, Maryland
  • 2 Department of Obstetrics and Gynecology, Stanford University School of Medicine, Stanford, California
  • 3 Center for Fetal Diagnosis and Treatment, Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania
  • 4 The Fetal Center, Department of Obstetrics and Gynecology, University of Texas Health Center, Houston
  • 5 Division of Maternal and Fetal Medicine, Department of Obstetrics and Gynecology, Mayo Clinic, Rochester, Minnesota
  • 6 Colorado Fetal Care Center, Children’s Hospital of Colorado, Aurora
  • 7 Department of Obstetrics and Gynecology, Keck School of Medicine, University of Southern California, Los Angeles
  • 8 Department of Obstetrics and Gynecology, University of California, San Francisco
  • 9 Department of Obstetrics and Gynecology, Columbia University Irving Medical Center, New York, New York
  • 10 Division of Cardiology, Department of Pediatrics, University of California, San Francisco
  • 11 Division of Neonatology, Department of Pediatrics and Adolescent Medicine, Mayo Clinic, Rochester, Minnesota
  • 12 Division of Neonatology, Department of Pediatrics, Johns Hopkins University, Baltimore, Maryland
  • 13 Division of Brain Injury Outcomes, Johns Hopkins University, Baltimore, Maryland
  • 14 Division of Maternal-Fetal Medicine, Department of Gynecology and Obstetrics, Johns Hopkins University, Baltimore, Maryland
  • 15 Tufts Clinical and Translational Science Institute, Division of Newborn Medicine, Tufts Children’s Hospital, Tufts University, Boston, Massachusetts
  • 16 Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland
  • 17 Division of Pediatric Nephrology, Johns Hopkins University School of Medicine, Baltimore, Maryland
  • 18 Division of Pediatric Nephrology and Hypertension, McGovern School at the University of Texas Health Science Center, Houston
  • 19 Berman Institute of Bioethics, Johns Hopkins University School of Medicine, Baltimore, Maryland
  • Editorial Bilateral Renal Agenesis—Interpreting the RAFT Trial Cynthia Gyamfi-Bannerman, MD, MS; Krishelle Marc-Aurele, MD; Karen Mestan, MD, MS JAMA

Question   In pregnancies complicated by anhydramnios due to fetal bilateral renal agenesis, do serial amnioinfusions instituted before 26 weeks’ gestation mitigate lethal pulmonary hypoplasia in neonates?

Findings   In this nonrandomized clinical trial, 82% of live-born infants survived to 14 days of life or longer and placement of dialysis access, but longer-term neonatal survival was reduced. Serial amnioinfusions were not associated with severe maternal complications.

Meaning   Prenatal serial amnioinfusions can mitigate neonatal lethal pulmonary hypoplasia in neonates with bilateral renal agenesis, but infants face substantial morbidity independent of lung function.

Importance   Early anhydramnios during pregnancy, resulting from fetal bilateral renal agenesis, causes lethal pulmonary hypoplasia in neonates. Restoring amniotic fluid via serial amnioinfusions may promote lung development, enabling survival.

Objective   To assess neonatal outcomes of serial amnioinfusions initiated before 26 weeks’ gestation to mitigate lethal pulmonary hypoplasia.

Design, Setting, and Participants   Prospective, nonrandomized clinical trial conducted at 9 US fetal therapy centers between December 2018 and July 2022. Outcomes are reported for 21 maternal-fetal pairs with confirmed anhydramnios due to isolated fetal bilateral renal agenesis without other identified congenital anomalies.

Exposure   Enrolled participants initiated ultrasound-guided percutaneous amnioinfusions of isotonic fluid before 26 weeks’ gestation, with frequency of infusions individualized to maintain normal amniotic fluid levels for gestational age.

Main Outcomes and Measures   The primary end point was postnatal infant survival to 14 days of life or longer with dialysis access placement.

Results   The trial was stopped early based on an interim analysis of 18 maternal-fetal pairs given concern about neonatal morbidity and mortality beyond the primary end point despite demonstration of the efficacy of the intervention. There were 17 live births (94%), with a median gestational age at delivery of 32 weeks, 4 days (IQR, 32-34 weeks). All participants delivered prior to 37 weeks’ gestation. The primary outcome was achieved in 14 (82%) of 17 live-born infants (95% CI, 44%-99%). Factors associated with survival to the primary outcome included a higher number of amnioinfusions ( P  = .01), gestational age greater than 32 weeks ( P  = .005), and higher birth weight ( P  = .03). Only 6 (35%) of the 17 neonates born alive survived to hospital discharge while receiving peritoneal dialysis at a median age of 24 weeks of life (range, 12-32 weeks).

Conclusions and Relevance   Serial amnioinfusions mitigated lethal pulmonary hypoplasia but were associated with preterm delivery. The lower rate of survival to discharge highlights the additional mortality burden independent of lung function. Additional long-term data are needed to fully characterize the outcomes in surviving neonates and assess the morbidity and mortality burden.

Trial Registration   ClinicalTrials.gov Identifier: NCT03101891

Bilateral renal agenesis is the most severe congenital anomaly of the fetal urinary tract, with a prevalence of approximately 1 in 3000 births. With this condition, fetal anuria leads to absence of amniotic fluid (anhydramnios) by the second trimester, when placental transudate is no longer sufficient to sustain amniotic fluid volume. 1 Quiz Ref ID This early-onset anhydramnios causes depressurization of the fetal airways, impairing pulmonary development and resulting in uniformly lethal pulmonary hypoplasia at birth. 2

Case observations in monoamniotic twins discordant for bilateral renal agenesis demonstrated that preservation of adequate amniotic fluid by the twin with normally functioning kidneys can result in adequate pulmonary development for both fetuses. This observation provided evidence that installation of intrauterine amniotic fluid as a fetal intervention might promote lung development, enabling postnatal respiratory survival in congenital bilateral renal agenesis. 2 - 6 In 1994, the first publication of serial amnioinfusions in a pregnancy complicated by fetal bilateral renal agenesis described survival without lethal pulmonary hypoplasia at birth. However, the neonate died at 23 days of life after unsuccessful dialysis. 7 In a subsequent report, amnioinfusions resulted in live birth without life-limiting pulmonary hypoplasia, thereby allowing successful institution of long-term dialysis and, eventually, kidney transplant. 8 , 9 Although these reports indicate that survival is possible with congenital bilateral renal agenesis after serial amnioinfusions, the safety, feasibility, and efficacy of serial amnioinfusions for this indication have not been established. 8

In August 2016, the National Institute of Diabetes and Digestive and Kidney Diseases and the Eunice Kennedy Shriver National Institute of Child Health and Human Development sponsored a workshop to define knowledge gaps related to anhydramnios secondary to severe congenital anomalies of the kidneys and urinary tract, including bilateral renal agenesis, and proposed a research agenda. 10 In the absence of data to inform an evidence-based approach to prenatal management of anhydramnios, the workshop report concluded that hypotheses regarding the safety and efficacy of amnioinfusions should be tested in the setting of institutional review board (IRB)–approved research. 10 The Renal Anhydramnios Fetal Therapy (RAFT) trial aimed to assess neonatal outcomes after serial amnioinfusions and to test the hypothesis that neonatal pulmonary survival without lethal pulmonary hypoplasia is possible after serial amnioinfusions in pregnancies complicated by anhydramnios from fetal anuria. Herein, we report the outcomes for participants with fetal bilateral renal agenesis.

This nonrandomized, open-label, prospective clinical trial was conducted at 9 fetal intervention centers in the United States (a list of sites is provided in eAppendix 1 in Supplement 1 ). The other centers within the North American Fetal Therapy Network agreed not to perform serial amnioinfusions for potentially eligible participants while the trial was ongoing. The trial design was previously described, 11 and the protocol (see Supplement 2 and Supplement 3 for trial protocol and statistical analysis plan, respectively) was approved by the Johns Hopkins Medicine IRB, which acted as the central IRB for all sites under a reliance agreement.

The RAFT trial data and safety monitoring board (DSMB) consists of 3 maternal-fetal medicine specialists (2 from the United States and 1 from Canada), 1 biostatistician, and 1 ethicist (eAppendix 1 in Supplement 1 ). The DSMB is convened every 6 months to review both maternal safety and neonatal outcome data.

To participate, RAFT centers were required to have a maternal-fetal medicine specialist with experience performing amnioinfusion procedures for oligohydramnios or anhydramnios (minimum of 15 amnioinfusion procedures performed by the maternal-fetal surgeon), as well as neonatology, pediatric surgery, and nephrology expertise to place dialysis access and perform dialysis in small (<2 kg) neonates. RAFT was designed with 2 parallel, noncomparative trial groups: an intervention group for patients electing serial amnioinfusions and an expectant management group for those electing only observational data collection throughout pregnancy and after delivery ( Figure ). Within each group, patients were further categorized by the underlying cause of anhydramnios: (1) fetal bilateral renal agenesis (initial recruitment goal of 35 maternal-fetal pairs) or (2) other causes of fetal kidney failure, including multicystic dysplastic kidneys or severe lower urinary tract outflow obstruction (recruitment goal of 35 maternal-fetal pairs). As noted above, this report presents the outcomes in the bilateral renal agenesis cohort only.

Individuals interested in the trial were prescreened by telephone and, if potentially eligible, they were offered a screening visit at a RAFT site. The Figure details screening and enrollment for the trial. Inclusion criteria were a maternal age of at least 18 years, singleton gestation with bilateral renal agenesis and anhydramnios, completed multidisciplinary consultations, ability to begin amnioinfusions by 26 weeks’ gestation, willingness to receive prenatal care and deliver at a RAFT center for those enrolled in the intervention group, and willingness to have postnatal infant care at a RAFT center until discharge home receiving long-term dialysis. Exclusion criteria were presence of any additional extrarenal congenital fetal anomalies, given the likelihood that they suggest a multisystem syndrome or could complicate neonatal dialysis provision; any significant pathogenic or likely significant pathogenic findings on karyotype or microarray; or obstetric contraindications to amnioinfusions (chorioamnionitis, placental abruption, preterm prelabor rupture of membranes [PPROM], cervical length <25 mm, severe maternal medical condition in pregnancy [including but not limited to uncontrolled diabetes, refractory hypertension, or other conditions known to increase risk of infection, poor placental function, or preterm delivery], maternal depression as assessed by a Beck Depression Inventory 12 score ≥17 refractory to treatment, or technical limitation precluding amnioinfusions).

In addition to counseling with a maternal-fetal medicine specialist, eligible parents received multidisciplinary counseling from a neonatologist, pediatric nephrologist, pediatric kidney transplant specialist, pediatric surgeon, licensed clinical social worker, and genetic counselor. Prenatal counseling is designed to inform potential participants, as much as possible, of the likely postnatal and lifetime clinical course of a newborn with end-stage kidney disease, and includes the potential limitation that a very small, premature, or ill neonate may not be a candidate for placement of dialysis access due to practical limitations. 13 The informed consent process may be conducted over several in-person visits to allow sufficient time for all questions to be addressed and verify voluntary participation. In accordance with US federal regulations regarding research involving a pregnant person and fetus and offering the prospect of direct benefit solely to the fetus, both parents were required to provide written informed consent to study participation. Participants could select the intervention group with serial amnioinfusions or the expectant management group. A preenrollment amnioinfusion was performed to exclude rupture of membranes as an etiology for anhydramnios and to allow for a more detailed sonographic fetal evaluation. Pregnant individuals enrolling in the expectant management group had the option to waive the diagnostic amnioinfusion.

Participants received ultrasound-guided percutaneous amnioinfusions of isotonic fluid (normal saline or lactated Ringer) with antibiotics every 2 to 12 days using a 20-gauge or 22-gauge needle with local anesthesia for comfort. The timing and volume of fluid instilled at each amnioinfusion ranged from 300 mL to 800 mL at the discretion of treating clinicians, with the goal of maintaining a normal amniotic fluid index for gestational age (eAppendix 2 in Supplement 1 ). The amnioinfusion interventions were conducted in the outpatient clinic or in the labor and delivery unit, with hospital admission only for specific indications such as prelabor rupture of membranes or preterm labor. Amnioinfusions were stopped if a participant experienced prelabor rupture of membranes. All participants had 2 fetal magnetic resonance imaging studies and 2 fetal echocardiograms during the study period: once during screening to identify any extrarenal anomalies not apparent on ultrasound, and the second at the 32-week assessment visit if the pregnancy was ongoing. The second magnetic resonance imaging was performed to assess the fetal brain as well as lung volumes, and the second echocardiogram was to assess fetal pulmonary vascular response to maternal hyperoxygenation for future exploratory analyses.

Delivery timing and mode were determined by obstetric indications. Newborns were admitted to the neonatal intensive care unit. Neonatal management, including initiation of kidney replacement therapy, was guided by local practice, individual patient needs, and shared decision-making with parents. For participants enrolled in the expectant management group, delivery could occur at the RAFT center or at a home hospital, if desired by the participant, and palliative neonatal care was provided according to the local protocol.

The primary outcome was a composite of neonatal survival to at least 14 days of life and placement of dialysis access. This was chosen as a surrogate for demonstrating both the absence of lethal pulmonary hypoplasia and the size and clinical stability required to allow initial management of end-stage kidney disease in a neonate. We report 3 of 5 prespecified secondary outcomes, 1 maternal and 2 neonatal/infant. Maternal pregnancy complications including PPROM and preterm labor were used to assess the safety and feasibility of the intervention. Neonatal/infant secondary outcomes included survival to hospital discharge receiving long-term dialysis and survival to kidney transplant. Exploratory outcomes included respiratory and dialysis support at 30, 60, and 90 days of life and neonatal survival at 30, 60, and 90 days of life, at hospital discharge, and at transplant. To understand infant morbidity associated with the intervention, specific aspects of infants’ medical course were captured, including need for invasive respiratory support, mode and duration of dialysis, and medical complications encountered during the initial hospitalization and after discharge, if applicable.

Sample size determination for the RAFT trial was based on the primary outcome of survival to at least 14 days of life and placement of dialysis access in the intervention group. For efficacy of serial amnioinfusions, we used exact methods to calculate 95% CIs around survival proportions from 0.2 to 0.8. A sample size of 35 maternal-fetal pairs in the intervention group was sufficient to show that the proportion of infants surviving to at least 14 days of life with dialysis access was greater than 30% (assuming the observed rate in the study is ≥50%). Normally distributed continuous variables are summarized as means with SDs and nonnormally distributed variables as medians with IQRs. Binary or categorical variables are summarized as frequencies and percentages. For each analysis, neonates were grouped into 2 categories based on the primary outcome (survival and nonsurvival to ≥14 days of life). Demographic and clinical characteristics were compared between the 2 groups using univariate analysis with the t test or Wilcoxon rank sum test for continuous variables depending on the normality of distribution, and the χ 2 or Fisher exact test for binary or categorical variables. For safety events, maternal adverse events and serious adverse events were recorded. Overall frequency and percentage per variable are reported for both events and participants. Neonatal respiratory support and dialysis type are reported as frequencies and percentages for all time points.

In response to investigator observations of long-term mortality and morbidity among infants surviving past the short-term primary end point, an interim analysis was performed after accrual of half of the planned sample size and presented to the DSMB. The boundaries for early stopping of the trial due to efficacy were ±4.3326 (corresponding to an α = .00001473). We report the 95% CI for survival at the primary outcome time of 14 days. For secondary outcomes, a 2-sided P  < .05 was considered statistically significant.

From December 2018 to July 2022, a total of 321 individuals underwent prescreening, of which 122 (38%) progressed to a screening visit at a RAFT site and 49 (15%) were eligible for screening for the bilateral renal agenesis group ( Figure ). Twenty-one (43%) of the screened individuals met inclusion criteria for enrollment in the bilateral renal agenesis group and provided written informed consent to participate; 18 (86%) underwent serial amnioinfusions and 3 (14%) participated in the expectant management group ( Table 1 ). On July 16, 2022, following the interim data analysis, the DSMB recommended suspending recruitment into the bilateral renal agenesis group due to the efficacy of the intervention based on the primary outcome variable, and concern that secondary infant outcomes including morbidity and mortality represented a high degree of burden. This report presents the results of the 21 maternal-fetal participant pairs.

In the expectant management group, all 3 pregnancies resulted in live birth and neonatal death within 12 hours due to severe pulmonary hypoplasia. In the amnioinfusion group, 17 pregnancies (94%) resulted in live birth at a median gestational age of 32 weeks, 4 days, and all participants delivered before 37 weeks’ gestation. There was 1 fetal demise at 24 weeks that was associated with PPROM after the second amnioinfusion. A total of 14 of 17 (82%; 95% CI, 44%-99%) live-born neonates who had amnioinfusions survived to at least 14 days and had placement of dialysis access.

Because neonatal survival without the intervention was 0%, no direct survival comparisons were made between neonates born to participants in the intervention group and those in the expectant management group. Factors associated with survival to the primary outcome were a greater number of amnioinfusions, a longer interval between the first amnioinfusion and PPROM, gestational age at birth of 32 weeks or greater, and higher birth weight ( Table 2 ).

No serious maternal adverse events occurred beyond hospitalization or needing to stop the intervention due to pregnancy complications. Maternal and pregnancy complications that were related to amnioinfusions included PPROM (61%), chorioamniotic membrane separation (28%), and vaginal bleeding (22%) ( Table 1 ).

Six (35%) of 17 live-born infants survived to discharge home from the hospital receiving long-term dialysis at a median of 24 weeks of age (range, 13-32 weeks). Two subsequently died; 1 due to infectious complications of dialysis at 2 years of age and 1 following cardiac arrest at home at 4 months of age. Three (50%) had strokes, 2 of whom remain long-term survivors. Seizure was the most common clinical symptom associated with stroke, and the pattern and timing of stroke differed among affected individuals ( Table 3 ). As of this report, no surviving individuals had undergone kidney transplant. Although all surviving individuals are transplant candidates, time and intensive nutritional support are required for growth to a size to allow surgical placement of donor kidney (minimum weight of approximately 10 kg). In addition, most infants with bilateral renal agenesis lack a lower urinary tract, which complicates planning for posttransplant urinary outflow management.

Survival to 30 days of age was identical to survival to at least 14 days (82%) but decreased over time, with 52% (9/17) and 47% (8/17) of infants surviving at 60 and 90 days, respectively. Sepsis (n = 6) was cited as the most common contributing cause of death in the clinical records ( Table 3 ). One infant had total intestinal aganglionosis identified postnatally and died at 6 months of age.

Table 3 summarizes the postnatal course, complications, and cause of death (if applicable) in infants with bilateral renal agenesis. All infants who had long-term dialysis access placed had peritoneal dialysis catheters placed, but multiple modes of kidney replacement therapy were listed for many. Reasons for exposure to multiple dialysis modes include infant size too small or clinical status too unstable to accommodate peritoneal dialysis catheter placement soon after birth, or peritoneal dialysis catheter malfunction. Available autopsy reports are included in Table 3 .

The eTable in Supplement 1 describes respiratory and dialysis support for hospitalized infants at each survival time point. Because intubation status was recorded only on the day of assessment, information on infants who may have been extubated and reintubated between time points is not captured. Multiple dialysis modes were used over time, and at some time points more than 1 dialysis mode was used simultaneously.

Assessing the relative safety and efficacy of an intervention with regard to both pregnant and neonatal participants adds an element of complexity to fetal intervention trials in general, as does the need to assess both short- and longer-term neonatal outcomes. Quiz Ref ID In the present multicenter trial involving singleton pregnancies with bilateral renal agenesis, serial amnioinfusions initiated before 26 weeks’ gestation mitigated lethal pulmonary hypoplasia in newborns and was associated with survival to at least 14 days of life and placement of dialysis access in 82% of neonates. However, survival beyond 14 days was lower, with only 35% of live-born infants surviving to hospital discharge receiving long-term dialysis, and none had undergone kidney transplant at the time of this report. Quiz Ref ID Although the results demonstrate the efficacy of the intervention to allow lung development, a significant degree of uncertainty remains regarding the longer-term burden of morbidity and mortality in surviving neonates. Notable maternal complications included PPROM and preterm delivery. All pregnancies in the intervention group and 2 of 3 in the expectant management group delivered at less than 37 weeks’ gestation. There were no severe maternal obstetric complications.

RAFT is a unique fetal intervention trial because of the involvement of 2 major organ systems. Neonates with bilateral renal agenesis who successfully survive from a pulmonary standpoint still lack functional kidneys and a lower urinary tract, may have disruption of renin-angiotensin-aldosterone pathways in the absence of kidney tissue, which may contribute to difficulty with blood pressure regulation, and require permanent life-sustaining kidney replacement therapy with dialysis and, eventually, kidney transplant. Reflecting this complexity, fewer than half (6/14) of infants who survived to the primary outcome were discharged home from the hospital. This survival rate is substantially lower than reported survival for infants receiving dialysis overall. Data from the US Renal Data System registry of infants starting peritoneal dialysis before 1 month of age from 2000 to 2014 reported 1- and 5-year survival as 86.1% and 74.6%, respectively, but these data do not account for infants who died before hospital discharge or prior to the initiation of long-term dialysis. 14 Claes et al 15 recently published neonatal survival data for a cohort of 213 infants who are perhaps more, but not completely, comparable with RAFT neonates; those born with kidney failure (not restricted to bilateral renal agenesis) at 52 US children’s hospitals whose data were collected via the Children’s Hospital Association Pediatric Health Information System database. In this study, mortality during the initial hospitalization was reported to be 23.9%. Mortality rates differed by birth weight, with 43.8% mortality among infants weighing less than 1800 g, 22.1% among those weighing 1800 to 2500 g, and 22.5% among those weighing more than 2500 g. 15 In the RAFT trial, 83% of newborns weighed less than 2500 g and similarly, lower birth weight was also associated with higher mortality. The higher mortality rate before hospital discharge suggests that infants born without kidneys experience life-limiting complications at a higher rate than infants with kidney failure from all causes.

Although this trial was not designed to evaluate secondary outcomes of neonatal morbidities, stroke was a notable complication observed in 2 of the 4 infants who remained long-term survivors at the time of this report, as well as in at least 2 neonates who died prior to hospital discharge ( Table 3 ). Several pathophysiologic mechanisms predispose patients with end-stage kidney failure to stroke, including acid-base imbalance, impaired cerebral autoregulation, and endothelial and platelet dysfunction, 16 but no data for neonatal stroke incidence and characteristics after initiation of dialysis exist for comparison. This observation was cited by the DSMB in their recommendation to stop recruitment into the bilateral renal agenesis group of the trial. The DSMB acknowledged that efficacy was demonstrated by achievement of the defined primary outcome in a statistically significant proportion of neonates, but raised concern for potential harm given the disparity between short- and long-term infant survival and the burden of morbidity in longer-term survivors, especially stroke. Further investigation of this complication is ongoing. This highlights an additional complexity associated with this fetal intervention; achieving longer-term survival in a novel cohort of neonates allows description of potential comorbidities that have been previously unrecognized.

At its inception, the need to assess outcomes for infants beyond respiratory survival alone and long-term morbidity for surviving neonates lacking kidneys was recognized as a critical component of the RAFT trial. In March 2017, a multidisciplinary conference was convened to describe the complex ethical concerns associated with use of serial amnioinfusions for bilateral renal agenesis. 13 Among the ethical concerns highlighted were the need for extensive and nondirected multidisciplinary counseling for potential maternal patients, the need to assess outcomes for infants beyond respiratory survival alone, quality of life for surviving neonates lacking kidneys and requiring lifelong care for end-stage kidney disease, the impact on families, and potential moral distress among health care personnel who must balance parental hope with perceived infant discomfort and distress. 13

Fetal intervention trials in general pose complex ethical challenges because both fetal and maternal risks and benefits must be considered. The potential hope offered to an expectant parent must be balanced with the potential lifelong burden associated with a chronic, complex medical condition. Invasive fetal interventions may be justified when the alternative to no intervention is a lethal perinatal outcome 13 ; in the case of bilateral renal agenesis, expected neonatal mortality is 100% without fetal intervention. In one paradigm, a potential parent and future child’s well-being may be closely aligned, especially when a single compromised organ system may be “corrected” via fetal intervention. However, the intervention in the RAFT trial can at best correct only the respiratory component of a severe pediatric chronic illness that will result in prolonged (and likely multiple) intensive care admissions, and the benefit of this to a potential child is less clear. Studies have also shown that parental quality of life is negatively affected by pediatric intensive care admissions and pediatric chronic illnesses 17 ; a qualitative exploration of the extent of this impact on enrolled families is planned. It is critical for future studies that long-term developmental outcomes be assessed in neonates who survive due to prenatal amnioinfusion treatment.

This trial had several strengths. It assessed the potential of a standardized intervention to ameliorate the fatal neonatal pulmonary hypoplasia associated with anhydramnios due to bilateral renal agenesis, while also assessing maternal safety. It was conducted based on a predefined ethical framework that defined critical exploratory secondary outcomes, including long-term neonatal survival to hospital discharge and to kidney transplant and quality of life. 13 The data generated from the trial to date will inform decision-making for affected families and clinicians considering offering this intervention as part of clinical prenatal care, as well as future research priorities in long-term follow-up of neonatal survivors.

This trial had several limitations. First, there was a notable lack of diversity among participants enrolled in RAFT. Zero participants identified as Black or African American, 11% with Hispanic ethnicity, and 94% as White. This lack of diversity in participants obviously limits the generalizability of the findings. Two potential socioeconomic barriers to enrollment include a requirement for adequate insurance coverage and the requirement to have both prenatal and postnatal care provided at 1 of the 9 RAFT centers, which in many cases requires family flexibility and resources to relocate for participation. A second limitation is small sample size. Although the initial target for recruitment was 35 maternal-fetal pairs with bilateral renal agenesis, enrollment was halted at 18. The trial was not powered to assess the secondary outcomes, including survival to hospital discharge and pediatric morbidities of end-stage kidney disease. Third, the limits of prenatal phenotyping should be acknowledged. Families considering amnioinfusions must be counseled that any additional organ system anomalies will further complicate already complex postnatal care. If additional abnormalities are identified postnatally, shared decision-making with parents may be necessary to determine if aggressive management of end-stage kidney disease should continue. Fourth, postnatal management of neonates was purposefully not standardized across the study sites for multiple reasons, including center differences in neonatal surgical approaches to placement of dialysis access and available modes of hemodialysis when needed. Advances in neonatal hemodialysis have occurred since the start of the trial, so this impact on survival cannot be estimated. Because all centers had multidisciplinary teams with the capability to provide neonatal intensive care and kidney replacement therapy, results of this trial should not be generalized to centers without these capabilities or to patients that do not meet eligibility criteria. Fifth, collection of longitudinal quality-of-life data from infants who survive to initial hospital discharge is ongoing in both groups of the RAFT trial and will be explored in future reports, but because infants must survive to hospital discharge before these data are collected, data available to date remain limited.

In summary, this study demonstrates that serial amnioinfusions initiated before 26 weeks’ gestation mitigated lethal pulmonary hypoplasia in the majority of neonates with bilateral renal agenesis. Survival to hospital discharge and beyond receiving peritoneal dialysis was substantially lower than survival to the short-term primary outcome and was strongly associated with gestational age at birth and birth weight, highlighting the burden of mortality independent of lung function for infants lacking kidneys. Because additional long-term data are needed to more fully characterize the outcomes in surviving neonates and assess the morbidity and mortality burden, this intervention is best offered with careful, multidisciplinary prenatal counseling in centers with collaborative multidisciplinary teams, including palliative care, with the capability to provide neonatal intensive care and kidney replacement therapy, and in the context of ongoing research.

Corresponding Author: Meredith A. Atkinson, MD, MHS, Division of Pediatric Nephrology, Johns Hopkins University School of Medicine, 200 N Wolfe St, Room 3064, Baltimore, MD 21287 ( [email protected] ).

Accepted for Publication: September 28, 2023.

Author Contributions: Drs J. Miller and Atkinson had full access to all of the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis.

Concept and design: J. Miller, Baschat, Rosner, Blumenfeld, Zaretsky, Gonzalez, R. Miller, Moon-Grady, Keiser, Jelin, Davis, Warren, Hanley, Atkinson.

Acquisition, analysis, or interpretation of data: J. Miller, Baschat, Rosner, Blumenfeld, Moldenhauer, Johnson, Schenone, Chmait, Gonzalez, R. Miller, Moon-Grady, Bendel-Stenzel, Avadhani, Hanley, Watkins, Samuels, Sugarman, Atkinson.

Drafting of the manuscript: J. Miller, Baschat, Blumenfeld, Schenone, Chmait, R. Miller, Keiser, Avadhani, Hanley, Watkins, Atkinson.

Critical review of the manuscript for important intellectual content: Baschat, Rosner, Blumenfeld, Moldenhauer, Johnson, Schenone, Zaretsky, Chmait, Gonzalez, R. Miller, Moon-Grady, Bendel-Stenzel, Keiser, Avadhani, Jelin, Davis, Warren, Hanley, Watkins, Samuels, Sugarman, Atkinson.

Statistical analysis: Avadhani, Watkins, Atkinson.

Obtained funding: Gonzalez, Davis, Hanley, Atkinson.

Administrative, technical, or material support: Baschat, Rosner, Blumenfeld, Johnson, Schenone, Zaretsky, Bendel-Stenzel, Keiser, Jelin, Davis, Warren, Watkins, Samuels.

Supervision: J. Miller, Baschat, Rosner, Schenone, Gonzalez, R. Miller, Bendel-Stenzel, Davis, Warren, Hanley, Atkinson.

Conflict of Interest Disclosures: Dr Samuels reported receipt of research funding from Travere Pharmaceuticals. Dr Sugarman reported receipt of personal fees from Merck KGaA, IQVIA, Aspen Neurosciences, Merck, and Biogen; receipt of meeting travel support from Merck KGaA and IQVIA; and holding stock options in Aspen Neurosciences. No other disclosures were reported.

Funding/Support: Research reported in this publication was supported by the Eunice Kennedy Shriver National Institute of Child Health and Human Development of the National Institutes of Health under award R01HD100540.

Role of the Funder/Sponsor: The funding organization had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; or decision to submit the manuscript for publication.

Data Sharing Statement: See Supplement 4 .

Additional Contributions: We acknowledge the late Eric B. Jelin, MD, who was a consummate pediatric surgeon and original principal investigator of the RAFT trial and who dedicated his life to caring for patients with congenital anomalies and their families. We thank the families who graciously participated in this study, along with the staff at each participating site. We acknowledge the North American Fetal Therapy Network executive board and the scientific review committee for contributing to the development of the multicenter protocol, and all of its members for supporting and directing potentially eligible participants to the trial and working group meeting; the Johns Hopkins University–Tufts Trial Innovation Center and the BIOS Clinical Trials Coordinating Center for consultation during the protocol development stage and trial management; the data and safety monitoring board (Elizabeth Thom, PhD [2017-2021], Laurence McCullough, PhD [2017-2022], Richard Brown, MD [2017-2023], Kathryn Drennan, MD [2017-2023], Patricia Santiago-Munoz, MD [2017-2023], Janet Malek, PhD [2022-2023], and Stephanie Leonard, PhD [2021-2023]); the Neonatology Working Group for their work evaluating practice patterns of neonatal management across sites and working toward developing a framework for practice guidelines (Kristin McKenna, MD, MPH, Valerie Chock, MD, Susan Hintz, MD, MS, Alexis Davis, MD, Suzanne Lopez, MD, Amir Khan, MD, and all RAFT site neonatology teams); the Nephrology Working Group for their collaboration in optimizing postnatal dialysis care (Christian Hanna, MD, MS, Rita Swinford, MD, and all RAFT site pediatric nephrology teams); the fetal echocardiography laboratory at the University of California, San Francisco, for blinded review of fetal echocardiograms; and Megan Singleton, JD, MBE, Human Research Protection Program, Johns Hopkins University School of Medicine, for her guidance in human subjects protection and advice from the beginning of trial design.

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May 21, 2024 — Researchers used 3D brain tissue structures called organoids to test a potential therapy for a rare disorder called Timothy syndrome.

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Six-in-ten U.S. adults say gun violence is a very big problem in the country today, up 9 percentage points from spring 2022.

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The pda, will we ever know what to do.

There are a few trials on-going, or near completion or, as this one, just published, that should give us insight into what to do about an open ductus in the very preterm. This trial has major limitations, but does give … Continue reading →

Not Neonatology: Oh Canada…. Warbler

Still on my trip to Ecuador, where I saw my first ever Canada Warbler. I know it is just a name, but it was most pleasing to find this bird, which does indeed migrate to Canada each year but I … Continue reading →

Not neonatology: a trip to Ecuador

A break in blogging for a couple of weeks, while I take a trip to Ecuador, with the main purpose of birdwatching and photography. Ecuador is the country with the greatest avian biodiversity in the world, and with and amazingly … Continue reading →

How much protein should we provide to the preterm in the first days of life?

Extremely preterm infants become catabolic rapidly after birth, with the sudden interruption of their trans-placental nutrient supply to the fetus, who becomes a baby that has tiny stores of fat or glycogen. We progressed in neonatology from starving preterm babies … Continue reading →

It’s Raining Antibiotics

Early onset sepsis is a serious condition with a substantial morbidity, and, thankfully, a relatively low mortality in recent years. Prompt recognition and early treatment are essential, but early clinical signs and risk factors tend to be non-specific. As a … Continue reading →

Do omega 3 fatty acids make preterm babies smarter?

It seems that they do, perhaps a little bit! There are now a confusing array of trials of supplementation of polyunsaturated fatty acids in preterm infants. They have compared various control diets to differing PUFA supplements. Many of them have … Continue reading →

Making intubation safer for the most fragile babies

Many, many years ago, when I was a young trainee physician, we learned almost everything “on the job”. I can’t remember the first patient I intubated, but there were no mannequins, and no simulations, the phrase “see one, do one, … Continue reading →

Time to stop placebo injections in neonatal research projects

Randomized controlled trials are the bedrock of evidence-based medicine. If a treatment has a good theoretical rationale, and preclinical data showing efficacy, the only way to prove efficacy in the human is to randomise patients to the treatment, compared to … Continue reading →

Protein pump inhibitors cause coeliac disease and asthma, and they are unnecessary.

OK, that title is perhaps slightly too definite, the publications that I wanted to discuss are observational studies, which can only prove associations, but it would be hard to perform the prospective controlled trials that would be necessary to prove … Continue reading →

Reducing pain from retinopathy screening

Retinopathy screening is undoubtedly painful for preterm babies, formal evaluation with PIPP scores routinely exceed 10 during screening, and may exceed 14, meaning moderate to severe pain. As a planned procedure there is always opportunity for pre-emptive analgesia prior to … Continue reading →

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Historic $35M fine announced against company that surrendered 4,000 beagles

The fine is the largest ever for animal welfare and clean water violations.

The Department of Justice and Environmental Protection Agency announced the largest ever fine under the Animal Welfare Act on Monday, totaling more than $35 million in criminal fines, donations and costs to upgrade their operations to be paid by a company that surrendered 4,000 beagles from a dog breeding facility in Virginia in 2022 .

In 2022, the DOJ secured the surrender of more than 4,000 dogs from a facility that bred and sold animals for research, saying the operators failed to meet minimum standards for humane treatment of the animals.

PHOTO: Priceless Pets volunteer Mary Green of Chino Hills, places new collars on some of the 200 beagles who were among 4,000 dogs freed from a Virginia breeding facility, moments after the dogs arrived in two trailers at Priceless Pets on July 23, 2022.

"Envigo compounded the heartbreaking nature of its animal welfare crimes by committing egregious Clean Water Act violations that undermined public health and the wellbeing of the animals in their care," David M. Uhlmann, assistant administrator of EPA's Office of Enforcement and Compliance Assurance, said in a statement.

"Everyone victimized in this precedent-setting animal welfare case deserved better: the workers, the beagles, the environment and the community," he said. "Envigo deserves every dollar of its record fine."

PHOTO: A veterinary technician carry beagles into Paw Prints Animal Hospital on Aug. 08, 2022 in Waldorf, Md.

The Animal Welfare Act is a federal law that sets minimum standards of care for animals in captivity, being used for research or educational settings, or being sold to the public. The dog breeding facility in Cumberland, Virginia, which is now closed, was cited for failing to provide adequate veterinary care to the animals in its facility as well as failing to meet requirements for adequate housing, food, and sanitation.

Many of the dogs rescued from the breeding facility in 2022 were adopted into new homes .

MORE: All 4,000 beagles now rescued from breeding facility under federal investigation

The parent company, Inotiv Inc, will now pay $35 million and be subject to a compliance monitor and increased standards for their operations, according to an EPA press release . One of the companies responsible for the facility, Envigo Global Services, pleaded guilty to conspiracy to violate the Clean Water Act for failing to operate wastewater treatment at the dog breeding facility and exposing dogs and people working in the facility to water that was contaminated with fecal matter and was released into a local waterway.

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Another company, Envigo RMS, pleaded guilty to conspiracy to violate the Animal Welfare Act by failing to provide veterinary care, adequate staffing and safe living conditions for the animals in the facility.

PHOTO: Marc Gup, a volunteer with the Animal Refuge League in Westbrook greets two beagles being unloaded from a Wings of Rescue plane at the Portland International Jetport on Sept. 4, 2022.

Inotiv Inc. is a company that provides services to support "nonclinical and analytical drug discovery and development services," including animal breeding, according to its website . In a statement on its website, the company said the agreement announced Monday will resolve the investigation into the facility.

"Inotiv's top priority has always been -- and remains -- practicing appropriate standards of animal welfare for our animals, while supporting the scientific objectives of the studies conducted. We strive to maintain facilities that are compliant with applicable federal, state, and local laws and regulations and consistent with our core value to always do the right thing. That is why we worked to reach this agreement, and why we have agreed to go above and beyond those legal requirements," the company said in the statement.

About $22 million of the payment is a criminal fine, about $3 million will be given to the Humane Society of the United States and Virginia Animal Fighting Taskforce, $3.5 million will be donated to the National Fish and Wildlife Foundation for ecosystem restoration and another $7 million will be used to update their facilities to higher standards than required under the Animal Welfare Act.

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  1. Neonatology

    Genetic testing in the neonatal ICU. First-line whole-genome sequencing may lead to more-focused clinical management for infants with a suspected genetic disease. Karen O'Leary. Research ...

  2. February 2022

    Advances in Neonatal Care takes a unique and dynamic approach to the original research and clinical practice articles it publishes. Addressing the practice challenges faced every day—caring for the 40,000-plus low-birth-weight infants in Level II and Level III NICUs each year—the journal promotes evidence-based care and improved outcomes for the tiniest patients and their families.

  3. March

    Hydrocortisone, with backup dexamethasone, to prevent Bronchopulmonary Dysplasia. Posted on28 March 2022by Keith Barrington. A trial that has been awaited for a while has just been published (Watterberg KL, et al. Hydrocortisone to Improve Survival without Bronchopulmonary Dysplasia. N Engl J Med. 2022;386 (12):1121-31).

  4. Advances in Neonatal Care

    2022 Clinical Article of the Year: Purposeful Language Exposure by Neonatal Nurses and Caregivers in the NICU. Ne wnam, Katherine M. et al. October 2021 - Volume 21 - Issue 5 - p 407-417. 2021 Research Article of the Year: Physiological Stability in Very Preterm Infants During Skin-to-Skin Contact as Assessed by Near-Infrared Spectroscopy ...

  5. Frontiers in Pediatrics

    KIRAN MORE. 6,800 views. 6 articles. Explores the field of fetal and neonatal medicine, aiming for reports that provide a valid and clear message for scientists and clinicians.

  6. Editorial: Case reports in neonatology 2022

    Editorial on the Research Topic Case reports in neonatology 2022. This Research Topic publishes high-quality case reports and case series in the field of neonatology, ranging from lethal poisoning, adverse drug reactions, congenital pathologies, neonatal metabolic disease, survival and care practices of periviable births to malignancies in newborns (Baptiste et al. Cheng et al. Gaertner et al ...

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    JAMA Network Open. Research. May 28, 2024. This diagnostic study examines whether the neonatal lung ultrasonography score has equivalent accuracy to predict surfactant need in neonates born late preterm and later as in neonates born more prematurely. Pediatrics Radiology Pulmonary Medicine.

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    The Impact of Comprehensive Fetal Care on Mortality of Children With Congenital Diaphragmatic Hernia when Delivery is Co-located in a Pediatric Hospital. J Pediatr Surg. 2023 Sep 27:S0022-3468 (23)00577-8. doi: 10.1016/j.jpedsurg.2023.09.039. Epub ahead of print. PMID: 37914590.

  9. Case Reports in Neonatology 2022

    Case Reports in Neonatology 2022. This Research Topic highlights high-quality Case Reports in Neonatology. Our Case Reports aim to highlight unique cases of patients that present with an unexpected/unusual diagnosis, treatment outcome, or clinical course. Case Reports provide insight into the differential diagnosis, decision making, and ...

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    6 July 2022. Two-year neurodevelopmental data for preterm infants born over an 11-year period in England and Wales, 2008-2018: a retrospective study using the National Neonatal Research Database. Emily van Blankenstein, Tia Sodiwala, Julia Lanoue, Neena Modi, Sabita N Uthaya, Cheryl Battersby. 19 February 2024.

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  12. Current Issue : Advances in Neonatal Care

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    Growing shares of Americans view both gun violence and violent crime as very big national problems. 49% of U.S. adults say gun ownership increases safety by allowing law-abiding citizens to protect themselves; an identical share says it reduces safety by giving too many people access to firearms and increasing misuse. short readsApr 26, 2023.

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  29. Historic $35M fine announced against company that surrendered 4,000

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